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Journal Article
International immunopharmacology, ISSN 1567-5769, 11/2013, Volume 17, Issue 3, pp. 638 - 650
Signaling | Receptors | Inflammation | Kinases | Neutrophils | Pharmacology & Pharmacy | Immunology | Life Sciences & Biomedicine | Science & Technology | Signal Transduction - immunology | Animals | Receptors, Cell Surface - immunology | Humans | Neutrophils - immunology | Selectins - immunology | Mycoses | Lectins | Fc receptors | Integrins | Index Medicus | FcR, Fc-receptor | GPI, glycosylphosphatidylinositol anchor | CLEC, C-type lectin | OSCAR, osteoclast-associated receptor | PKB, protein kinase B | DAG, diacyl-glycerol | Tyk2, tyrosine protein kinase 2 | VCAM-1, vascular cell adhesion molecule 1 | ICAM-1, intercellular adhesion molecule 1 | FADD, Fas-associated protein with death domain | IκB, inhibitor of NF-κB | GM-CSF, granulocyte | MyD88, myeloid differentiation protein 88 | TNF, tumor necrosis factor | LTβ, lymphotoxin β | TRADD, TNFR1-associated death domain protein | Abl, Abelson leukemia proto-oncogene | SLP-76, SH2 domain-containing leukocyte protein of 76 kDa | CALDAG-GEFI, calcium and DAG-regulated guanine nucleotide exchange factor I | IL, interleukin | Src, Rous sarcoma virus proto-oncogene | IRF, IFN regulatory factor | RIG, retinoic acid-inducible gene | PLC, phospholipase C | TCR, T-cell receptor | IKK, IκB kinase | ITAM, immunoreceptor tyrosine-based activation motif | CARD, caspase activation and recruitment domain | IP3, inositol-tris-phosphate | CHO, Chinese hamster ovary cells | MKK, MAP kinase kinase | fMLP, formly-Met-Leu-Phe | TRAF, TNF receptor-associated factor | MIP, macrophage inflammatory protein | Rac, Ras-related C3 botulinum toxin substrate | monocyte colony-stimulating factor | PIP3, phosphatidylinositol-3-phosphate | VLA-4, very late antigen 4 (α4β1 integrin) | PAF, platelet activating factor | STAT, signal transducer and activator of transcription | TAK, TGFβ-activated kinase 1 | Mac-1, macrophage antigen 1 (αMβ2 integrin) | FcRγ, Fc-receptor γ-chain | Asc, apoptosis-associated speck-like protein containing a CARD | cIAP, cellular inhibitor of apoptosis | BCR, B-cell receptor | Fgr, Gardner–Rasheed feline sarcoma proto-oncogene | VASP, vasodilator-stimulated phosphoprotein | Hck, hematopoietic cell kinase | TGFβ, transforming growth factor β | Rap, Ras-related protein | SHP-1, SH2 domain-containing protein tyrosine phosphatase 1 | Syk, spleen tyrosine kinase | GPCR, G protein-coupled receptor | G-CSF, granulocyte colony-stimulating factor | TREM, triggering receptor expressed on myeloid cells | DISC, death-inducing signaling complex | MDL-1, myeloid DAP12-associating lectin 1 | C3G, Crk SH3 domain-binding guanine nucleotide exchange factor (RapGEF1) | NF-κB, nuclear factor κB | ERM, ezrin-radixin-moesin | Epac1, exchange protein activated by cyclic AMP 1 | LTB4, leukotriene B4 | Mcl, macrophage C-type lectin | SAP130, Sin3A-associated protein of 130 kDa | SH2, Src-homology 2 domain | MAP kinase, mitogen-activated protein kinase | PSGL-1, P-selectin glycoprotein ligand | PI3K, phoshoinositide-3-kinase | ADAP, adhesion and degranulation promoting adapter protein (Fyb, SLAP-130) | NLRP3, NOD-like receptor family, pyrin domain containing 3 | MDA5, melanoma differentiation-associated protein 5 | TLR, Toll-like receptor | GRK, GPCR kinase | LAD, leukocyte adhesion deficiency | MAPKAP-kinase, MAP kinase-associated protein kinase | ZAP-70, ζ-chain-associated protein of 70 kDa | TRAIL, TNF-related apoptosis-inducing ligand | JNK, c-Jun N-terminal kinase | LFA-1, lymphocyte function-associated receptor 1 (αLβ2 integrin) | ROS, reactive oxygen species | RIP3, receptor-interacting serine-threonine protein kinase 3 | DAP12, DNAX activating protein 12 | IFN, interferon | PIR, paired immunoglobulin-like receptor | PKC, protein kinase C | PAK, p21-activated kinase | ESL-1, E-selectin ligand 1 | GAP, GTPase activating protein | ERK, extracellular signal-regulated kinase | SOCS, suppressor of cytokine signaling | JAK, Janus kinase | RANK, receptor activator of NF-κB | IRAK, IL-1 receptor-associated kinase | NOD, nucleotide-binding oligomerization domain containing protein | CEACAM3, carcinoembryonic antigen-related cell adhesion molecule 3 (CD66b)
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 05/2018, Volume 128, Issue 5, pp. 2042 - 2047
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 12/2007, Volume 282, Issue 50, pp. 36223 - 36229
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Mycobacterium tuberculosis - immunology | Ubiquitin - metabolism | NF-kappa B - metabolism | Nod2 Signaling Adaptor Protein - genetics | Ubiquitination - drug effects | TNF Receptor-Associated Factor 6 - genetics | Toll-Like Receptors - metabolism | Receptor-Interacting Protein Serine-Threonine Kinases - immunology | Macrophages - microbiology | MAP Kinase Kinase Kinases - genetics | Toll-Like Receptors - immunology | Myeloid Differentiation Factor 88 - genetics | Ubiquitin-Protein Ligases - metabolism | Nod2 Signaling Adaptor Protein - immunology | Ubiquitin-Conjugating Enzymes - genetics | MAP Kinase Kinase Kinases - metabolism | Ubiquitin - genetics | MAP Kinase Kinase Kinases - immunology | Mice, Knockout | Acetylmuramyl-Alanyl-Isoglutamine - pharmacology | Macrophages - metabolism | Nod2 Signaling Adaptor Protein - metabolism | Signal Transduction - drug effects | Ubiquitin-Conjugating Enzymes - metabolism | Toll-Like Receptors - genetics | I-kappa B Kinase - immunology | Mice | Ubiquitin-Protein Ligases - genetics | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Adjuvants, Immunologic - pharmacology | NF-kappa B - immunology | TNF Receptor-Associated Factor 6 - immunology | Extracellular Signal-Regulated MAP Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - genetics | Enzyme Activation - immunology | Signal Transduction - immunology | Ubiquitin-Protein Ligases - immunology | I-kappa B Kinase - metabolism | Myeloid Differentiation Factor 88 - immunology | Receptor-Interacting Protein Serine-Threonine Kinase 2 | Ubiquitin-Conjugating Enzymes - immunology | Tuberculosis - metabolism | Macrophages - immunology | Cells, Cultured | Ubiquitination - immunology | I-kappa B Kinase - genetics | Enzyme Activation - drug effects | Tuberculosis - immunology | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Animals | NF-kappa B - genetics | Tuberculosis - genetics | TNF Receptor-Associated Factor 6 - metabolism | Myeloid Differentiation Factor 88 - metabolism | Ubiquitin - immunology | Index Medicus
Journal Article
Immunity (Cambridge, Mass.), ISSN 1074-7613, 04/2017, Volume 46, Issue 4, pp. 635 - 648
myeloid cells | SYK | RIPK3 | MLKL | autoinflammation | Ptpn6 | IL-1β | IL-1α | MyD88 | SHP1 | TAK1 | necrosis | RIPK1 | Life Sciences & Biomedicine | Immunology | Science & Technology | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - immunology | Phosphorylation | Interleukin-1alpha - immunology | Skin Diseases - genetics | Humans | Immunoblotting | Interleukin-1alpha - metabolism | Syk Kinase - immunology | Signal Transduction - immunology | Inflammation - metabolism | Flow Cytometry | Syk Kinase - genetics | HEK293 Cells | Myeloid Differentiation Factor 88 - immunology | Interleukin-1alpha - genetics | Receptor-Interacting Protein Serine-Threonine Kinases - immunology | Skin Diseases - metabolism | MAP Kinase Kinase Kinases - genetics | Receptors, Interleukin-1 - immunology | Myeloid Differentiation Factor 88 - genetics | Skin Diseases - immunology | Inflammation - immunology | MAP Kinase Kinase Kinases - metabolism | Signal Transduction - genetics | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - genetics | MAP Kinase Kinase Kinases - immunology | Mice, Knockout | Receptors, Interleukin-1 - metabolism | Models, Immunological | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Syk Kinase - metabolism | Animals | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - metabolism | Inflammation - genetics | Mutation | Myeloid Differentiation Factor 88 - metabolism | Disease | SHP-1 protein | Crosstalk | Interleukin | Licenses | Interleukin 1 receptors | Kinases | Phosphatase | Inflammatory diseases | Proteins | Coding | Rodents | Interleukin 1 | Post-translation | Bone marrow | Skin diseases | Tumor necrosis factor-TNF | Protein-tyrosine kinase | Activation analysis | Immune system | Tyrosine | TAK1 protein | Neutrophils | Leukocytes (neutrophilic) | Inflammation | Roles | Scaffolding | Point mutation | MyD88 protein | Syk protein | Index Medicus
Journal Article
Nature immunology, ISSN 1529-2908, 03/2015, Volume 16, Issue 4, pp. 354 - 365
Life Sciences & Biomedicine | Immunology | Science & Technology | Inflammation - pathology | Interleukin-1 - genetics | RNA, Small Interfering - genetics | RNA-Binding Proteins - genetics | Humans | Receptors, Interleukin-1 - genetics | NF-kappa B - immunology | Receptor Protein-Tyrosine Kinases - immunology | Proto-Oncogene Proteins c-fyn - genetics | Signal Transduction - immunology | TOR Serine-Threonine Kinases - genetics | PTEN Phosphohydrolase - immunology | RNA, Small Interfering - immunology | Receptors, Interleukin-1 - deficiency | Leukocytes, Mononuclear - immunology | c-Mer Tyrosine Kinase | Interleukin-1 - immunology | Interleukin-18 Receptor alpha Subunit - genetics | Proto-Oncogene Proteins - immunology | Proto-Oncogene Proteins c-fyn - immunology | STAT3 Transcription Factor - genetics | Cell Line | PTEN Phosphohydrolase - genetics | Interleukin-18 Receptor alpha Subunit - immunology | Leukocytes, Mononuclear - drug effects | MAP Kinase Kinase Kinases - genetics | Receptors, Interleukin-1 - immunology | RNA-Binding Proteins - immunology | Gene Expression Regulation | Mice, Transgenic | Proto-Oncogene Proteins - genetics | Inflammation - immunology | Immunity, Innate | MAP Kinase Kinase Kinases - immunology | Interleukin-18 Receptor alpha Subunit - antagonists & inhibitors | Leukocytes, Mononuclear - pathology | TOR Serine-Threonine Kinases - immunology | Animals | NF-kappa B - genetics | Receptor Protein-Tyrosine Kinases - genetics | Lipopolysaccharides - pharmacology | Inflammation - genetics | Protein Binding | Mice | STAT3 Transcription Factor - immunology | Receptors, Interleukin-1 - antagonists & inhibitors | Index Medicus
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 08/2014, Volume 124, Issue 8, pp. 3566 - 3578
Journal Article