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Oncotarget, ISSN 1949-2553, 04/2018, Volume 9, Issue 30, pp. 21444 - 21458
The PI3Kα signaling pathway is frequently hyper-activated in breast cancer (BrCa), as a result of mutations/amplifications in oncogenes (e.g. ), decreased... 
Breast cancer | MAP3K1 | CRISPR gene editing | PIK3CA | Luminal A
Journal Article
Gene, ISSN 0378-1119, 11/2019, Volume 718, pp. 144072 - 144072
Disorders of sex development (DSDs) are congenital conditions in which chromosomal, gonadal and sex is atypical. It is difficult to diagnose and manage... 
MAP3K1 | Disorders of sex development | SRY | Whole exome sequencing | 46,XY complete gonadal dysgenesis | Index Medicus
Journal Article
Developmental Biology, ISSN 0012-1606, 08/2018, Volume 440, Issue 2, pp. 129 - 136
Morphogenesis is a complex and highly coordinated process orchestrated by temporal spatial activity of developmental pathways. How the different pathways... 
Embryonic eyelid closure | DKK2, JNK | MAP3K1 | Canonical Wnt signaling | Wntless | ACTIVATED PROTEIN-KINASE | MEKK1 | CLOSURE | DEVELOPMENTAL BIOLOGY | GLYCOGEN-SYNTHASE KINASE-3-BETA | MORPHOGENESIS | EYELID DEVELOPMENT | GENE | WNT/BETA-CATENIN | CELL-MIGRATION | C-JUN | Index Medicus | canonical Wnt signaling | JNK | DKK2
Journal Article
European Journal of Human Genetics, ISSN 1018-4813, 2019, Volume 27, Issue 6, pp. 869 - 878
Roma are a socially and culturally distinct isolated population with genetically divergent subisolates, residing mainly across Central, Southern, and Eastern... 
SURVIVAL | CYTOARCHITECTURE | POPULATION | GJB2 | W24X MUTATION | MAP3K1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENETICS & HEREDITY | HEALTH | Calponin | Hearing | USH2A protein | Preservation | Etiology | Hair cells | Homology | Scaling | Genetic diversity | Hearing impairment | Population genetics | Multidimensional scaling
Journal Article
Clinical Dysmorphology, ISSN 0962-8827, 2018, Volume 27, Issue 1, pp. 4 - 5
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 05/2019, Volume 113, pp. 108760 - 108760
MicroRNAs (miRNAs) are a class of small non-coding RNAs that are closely associated with carcinogenesis. Accumulating data indicate that miR-196b participates... 
Human choriocarcinoma cell | MAP3K1 | Hydatidiform mole | miR-196b | Migration | Proliferation | Invasion | MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATED PROTEIN-KINASE | METASTASIS | MEKK1 | OVARIAN-CANCER | MICRORNA-196B | GROWTH | MIR-675 | DISEASE | PHARMACOLOGY & PHARMACY | EXPRESSION
Journal Article
Lancet, The, ISSN 0140-6736, 2010, Volume 375, Issue 9732, pp. 2143 - 2151
Journal Article
世界胃肠病学杂志:英文版(电子版), ISSN 1007-9327, 2015, Issue 19, pp. 5867 - 5876
AIM To investigate the underlying molecularmechanisms of miR-451 to inhibit proliferation ofesophageal carcinoma cell line EC9706.METHODS: Assays for cell... 
squamous | kinase | inhibitor | Esophageal | carcinoma;MiR-451 | Proliferation | cell | Cyclin-dependent | 2D;MAP3K1
Journal Article
SpringerPlus, ISSN 2193-1801, 12/2016, Volume 5, Issue 1, pp. 1 - 12
Recent investigations have highlighted that therapeutic artificial microRNAs could be promising candidates for cancer therapy through the modulation of tumor... 
Breast cancer | MAP3K1 | Artificial miRNA | Metastasis | Tumor growth | CELLS | ACTIVATED PROTEIN-KINASE | RAS | MULTIDISCIPLINARY SCIENCES | P38 MAPK | KAPPA-B | MICRORNAS | INHIBITION | INTERFERENCE | EXPRESSION
Journal Article
by Yang, J and Zheng, W and Xu, Z and Chen, JF
ONCOTARGETS AND THERAPY, ISSN 1178-6930, 2019, Volume 12, pp. 6843 - 6855
Background: For patients with gastric cancer (GC), adjuvant chemotherapy is a standard therapy. However, the responses to the treatment are quite different.... 
adjuvant chemotherapy | SIGNALING PATHWAYS | ACTIVATION | gastric cancer | PROGNOSIS | OXALIPLATIN | MECHANISMS | DRUG-RESISTANCE | MAP3K1 rs889312 | biomarker | GENE POLYMORPHISMS | CISPLATIN | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | INHIBITORS | single-nucleotide polymorphism | MAPK PATHWAY | Adjuvant chemotherapy | Biomarker | Gastric cancer | Genetic polymorphism
Journal Article
Journal Article
International journal of cancer. Journal international du cancer, ISSN 0020-7136, 2/2009, Volume 124, Issue 3, pp. 729 - 733
Recent genome-wide scans identified several novel breast cancer risk alleles, including variants of the FGFR2 , MAP3K1 , and LSP1 genes, and a study of... 
MAP3K1 | LSP1 | genetic susceptibility | ovarian cancer | FGFR2
Journal Article
SpringerPlus, 12/2016, Volume 4, Issue 1, pp. 1 - 12
Recent investigations have highlighted that therapeutic artificial microRNAs could be promising candidates for cancer therapy through the modulation of tumor... 
MAP3K1 | Addiction | Tumor growth | Science | medium spiny neurons | behaviour | Breast cancer | Artificial miRNA | Metastasis | Science, general
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 10/2012, Volume 135, Issue 3, pp. 715 - 724
Journal Article