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Genes and Cancer, ISSN 1947-6019, 2011, Volume 2, Issue 3, pp. 195 - 209
The extracellular signal-regulated kinase 1/2 (ERK1/2) cascade is a central signaling pathway that regulates a wide variety of stimulated cellular processes,... 
Nucleus | MEK | Mitochondria | Golgi | MAPK | ERK | mitochondria | Monographs | nucleus
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 2007, Volume 1773, Issue 8, pp. 1213 - 1226
The ERK signaling cascade is a central MAPK pathway that plays a role in the regulation of various cellular processes such as proliferation, differentiation,... 
MEK | MAPK | Signaling specificity | ERK | signaling specificity | ACTIVATED PROTEIN-KINASE | EXTRACELLULAR-REGULATED KINASE | EARLY GENE-PRODUCTS | CYTOPLASMIC LOCALIZATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ERK MAP KINASE | CELL-CYCLE CONTROL | NUCLEAR TRANSLOCATION | PHOSPHORYLATION SITES | CELL BIOLOGY | PTP-SL | EPIDERMAL-GROWTH-FACTOR | Methyl ethyl ketone
Journal Article
The Plant Journal, ISSN 0960-7412, 08/2010, Volume 63, Issue 4, pp. 599 - 612
Plants recognize potential microbial pathogens through microbial‐associated molecular patterns (MAMPs) and activate a series of defense responses, including... 
MAPK cascade | MAMP | rice | gene expression | phytoalexin | DEFENSE RESPONSES | NICOTIANA-BENTHAMIANA | ARABIDOPSIS-THALIANA | ACTIVATED PROTEIN-KINASE | PHYTOALEXIN BIOSYNTHESIS | PLANT-DISEASE RESISTANCE | PLANT SCIENCES | HYPERSENSITIVE CELL-DEATH | HYDROGEN-PEROXIDE | TRANSCRIPTION FACTOR | GIBBERELLIN METABOLISM | Reactive Oxygen Species - metabolism | Sesquiterpenes - metabolism | Oligonucleotide Array Sequence Analysis | Oryza - metabolism | Immunoblotting | Plant Diseases - microbiology | Chitin - physiology | Gene Expression Profiling | Immunity, Innate | Reverse Transcriptase Polymerase Chain Reaction | MAP Kinase Signaling System | Host-Pathogen Interactions | Plant Proteins - genetics | Lignin - biosynthesis | Spectrometry, Mass, Electrospray Ionization | Oryza - genetics | Fungi - physiology | Oryza - microbiology | Gene Expression Regulation, Plant | Mitogen-Activated Protein Kinases - genetics | Plant Diseases - genetics | Plant Proteins - metabolism | Diterpenes - metabolism | Mitogen-Activated Protein Kinases - metabolism | Glucose metabolism | Lignin | Phytoalexin | Cell death | Chitin | Universities and colleges | Gene expression | Protein kinases | Plant metabolites | Rice | Signal transduction | Plant diseases | Metabolites | Plant biology | Defense mechanisms | Biosynthesis | Kinases | Pathogens | Phytoalexins | Reactive oxygen species | Translation | Cell division | Antimicrobial agents | MAP kinase | diterpenes | Secondary metabolites | Glycolysis | phenylpropanoids | Index Medicus | Original
Journal Article
Journal Article
Apoptosis, ISSN 1360-8185, 12/2008, Volume 13, Issue 12, pp. 1450 - 1464
Withaferin A (WA) is present abundantly in Withania somnifera, a well-known Indian medicinal plant. Here we demonstrate how WA exhibits a strong... 
Biochemistry, general | Withaferin A | Transcription factors | Myeloid leukemia | Oncology | Virology | Cell Biology | Biomedicine | Acute lymphoblastic leukemia | Cancer Research | Activation of p38 MAPK | Apoptosis | Mitochondrial death cascade | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEAT-SHOCK | INDUCTION | CHILDREN | CELL BIOLOGY | INHIBITION | ASHWAGANDHA | ACUTE LYMPHOBLASTIC-LEUKEMIA | WITHANIA-SOMNIFERA | LEISHMANIA-DONOVANI | EXPRESSION | RNA, Small Interfering - genetics | MAP Kinase Signaling System - physiology | Leukemia - pathology | Ergosterol - chemistry | Apoptosis - drug effects | Humans | Leukemia - metabolism | Membrane Potential, Mitochondrial - drug effects | Ergosterol - analogs & derivatives | Dose-Response Relationship, Drug | Proto-Oncogene Proteins c-bcl-2 - metabolism | Caspases - metabolism | Ergosterol - pharmacology | Molecular Structure | p38 Mitogen-Activated Protein Kinases - metabolism | Cell Survival - drug effects | Plants, Medicinal - chemistry | Tumor Cells, Cultured - drug effects | bcl-2-Associated X Protein - metabolism | p38 Mitogen-Activated Protein Kinases - genetics | Mitochondria - metabolism | Mitochondria - drug effects | Caspase Inhibitors | Poly(ADP-ribose) Polymerases - metabolism | Animals | Withanolides | Mice | Enzyme Activation | Medicine, Traditional | RNA, Small Interfering - metabolism | Cytochrome c | Chemotherapy | RNA | Chemical plants | Medicine, Botanic | Leukemia | Heat shock proteins | Medicine, Herbal | DNA binding proteins | Protein kinases | Cancer | Index Medicus
Journal Article
Trends in Plant Science, ISSN 1360-1385, 07/2015, Volume 20, Issue 7, pp. 405 - 407
Journal Article
Archives of Toxicology, ISSN 0340-5761, 2/2013, Volume 87, Issue 2, pp. 259 - 268
Journal Article
Archives of Biochemistry and Biophysics, ISSN 0003-9861, 11/2012, Volume 527, Issue 2, pp. 113 - 118
Journal Article
Leukemia, ISSN 0887-6924, 02/2017, Volume 31, Issue 2, pp. 446 - 458
Journal Article