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Journal of Clinical Investigation, ISSN 0021-9738, 12/2012, Volume 122, Issue 12, pp. 4555 - 4568
Increased mucus production is a common cause of morbidity and mortality in inflammatory airway diseases, including asthma, chronic obstructive pulmonary... 
MEDICINE, RESEARCH & EXPERIMENTAL | OBSTRUCTIVE PULMONARY-DISEASE | ACTIVATED PROTEIN-KINASE | BRONCHIAL EPITHELIAL-CELLS | HUMAN MUC5AC MUCIN | P38 MAPK | MEMBRANE-PROTEIN | LUNG-DISEASE | ASTHMA | VIRAL-INFECTION | RATIONAL DESIGN | Respiratory System - pathology | Interleukin-13 - physiology | Epithelial Cells - drug effects | Humans | Crystallography, X-Ray | Chloride Channels - genetics | Gene Knockdown Techniques | MAP Kinase Signaling System | Epithelial Cells - secretion | Pyrazoles - chemistry | Mitogen-Activated Protein Kinase 13 - antagonists & inhibitors | RNA Interference | Drug Design | Mitogen-Activated Protein Kinase 13 - chemistry | Mitogen-Activated Protein Kinase 13 - metabolism | Mucins - metabolism | Mitogen-Activated Protein Kinase 13 - genetics | Pulmonary Disease, Chronic Obstructive - metabolism | Binding Sites | Pyrazoles - pharmacology | Naphthalenes - chemistry | Cells, Cultured | Gene Expression Regulation | Models, Molecular | Mucus - secretion | Respiratory System - secretion | Naphthalenes - pharmacology | Chloride Channels - metabolism | Secretory Pathway - drug effects | Hydrogen Bonding | Protein Binding | Kinetics | Chloride Channels - physiology | Mucins - genetics | Respiratory mucosa | Interleukins | Genetic aspects | Research | Gene expression | Properties | Airway (Medicine) | Mitogen-activated protein kinases | Index Medicus | Abridged Index Medicus | Epithelial cells | Mortality | Cystic fibrosis | Mucus | Drug development | Inflammatory diseases | Morbidity | Asthma | Signal transduction | Molecular modelling | chloride channels (calcium-gated) | Chloride channels | Respiratory tract diseases | Chronic obstructive pulmonary disease
Journal Article
Journal Article
Journal Article
eLife, ISSN 2050-084X, 01/2017, Volume 6
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 08/2011, Volume 49, Issue 8, pp. 1745 - 1752
► The inhibitory effects of fucoidan on LPS-induced pro-inflammatory mediators in BV2 microglia were investigated. ► Fucoidan inhibited production of NO and... 
PGE2 | NF-κB | Fucoidan | Akt | MAPK | PATHWAYS | FOOD SCIENCE & TECHNOLOGY | ANTICOAGULANT | NEUROTOXICITY | ANTITUMOR | PGE | NF-kappa B | DISEASES | POLYSACCHARIDES | NITRIC-OXIDE | TOXICOLOGY | RECEPTORS | EXPRESSION | MOLECULAR-MECHANISMS | Tumor Necrosis Factor-alpha - metabolism | Microglia - metabolism | Plant Extracts - pharmacology | Tumor Necrosis Factor-alpha - genetics | Fucus - chemistry | JNK Mitogen-Activated Protein Kinases - metabolism | NF-kappa B - metabolism | Interleukin-1beta - genetics | Lipopolysaccharides - adverse effects | Proto-Oncogene Proteins c-akt - genetics | Cyclooxygenase 2 - genetics | Interleukin-1beta - metabolism | Chemokine CCL2 - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | JNK Mitogen-Activated Protein Kinases - genetics | Proto-Oncogene Proteins c-akt - metabolism | Microglia - cytology | Rabbits | NF-kappa B - antagonists & inhibitors | Microglia - drug effects | Anti-Inflammatory Agents - pharmacology | Nitric Oxide - antagonists & inhibitors | Down-Regulation | Cells, Cultured | p38 Mitogen-Activated Protein Kinases - genetics | Chemokine CCL2 - genetics | Polysaccharides - pharmacology | Dinoprostone - metabolism | Animals | Mitogen-Activated Protein Kinases - antagonists & inhibitors | NF-kappa B - genetics | Nitric Oxide Synthase Type II - genetics | Cyclooxygenase 2 - metabolism | Mitogen-Activated Protein Kinases - genetics | Mice | Dinoprostone - antagonists & inhibitors | Nitric Oxide - metabolism | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Mitogen-Activated Protein Kinases - metabolism | Nitric Oxide Synthase Type II - metabolism | Index Medicus
Journal Article
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 2018, Volume 43, Issue 2, pp. 362 - 372
Journal Article
Cancer Research, ISSN 0008-5472, 09/2015, Volume 75, Issue 17, pp. 3623 - 3635
Journal Article
Journal Article