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amino acid sequence (2) 2
animals (2) 2
biochemistry & molecular biology (2) 2
cell line (2) 2
enzyme activation (2) 2
erk, extracellular-signal-regulated kinase (2) 2
humans (2) 2
life sciences (2) 2
life sciences & biomedicine (2) 2
mapk, mitogen-activated protein kinase (2) 2
mapkap-k, mapk-activated protein kinase (2) 2
msk, mitogen- and stress-activated protein kinase (2) 2
phosphorylation (2) 2
research article (2) 2
rsk, p90 ribosomal s6 kinase (2) 2
science & technology (2) 2
3-phosphoinositide-dependent protein kinase 1 (1) 1
[sdv.neu]life sciences [q-bio]/neurons and cognition [q-bio.nc] (1) 1
aicar, aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (1) 1
ampk, amp-activated protein kinase (1) 1
anti-cancer drugs (1) 1
atf2, activating transcription factor 2 (1) 1
atm, ataxia telangiectasia mutated (1) 1
brsk, brain-specific kinase (1) 1
cak, cyclin-dependent kinase-activating kinase (1) 1
calcium/calmodulin dependent kinase (1) 1
camk (1) 1
camk, calmodulin-dependent kinase (1) 1
camkk, camk kinase (1) 1
camp and calcium responsive element (1) 1
camp and calcium responsive element binding protein (1) 1
camp-dependent kinase (1) 1
cbp (1) 1
cdk, cyclin-dependent protein kinase (1) 1
central nervous system (1) 1
chk, checkpoint kinase (1) 1
ck, casein kinase (1) 1
cns (1) 1
constitutive transcription factor (1) 1
cre (1) 1
creb (1) 1
creb binding protein (1) 1
csk, c-terminal src kinase (1) 1
ctf (1) 1
dmem, dulbecco's modified eagle's medium (1) 1
drug design (1) 1
drug discovery (1) 1
dyrk, dual-specificity tyrosine-phosphorylated and -regulated kinase (1) 1
ef2k, elongation-factor-2 kinase (1) 1
egf, epidermal growth factor (1) 1
eph-a2, ephrin a2 receptor (1) 1
erk (1) 1
extracellular-signal regulated kinase (1) 1
extracellular-signal-regulated kinase (1) 1
fgf-r, fibroblast-growth-factor receptor (1) 1
fkbp, fk506-binding protein (1) 1
fmk, fluoromethylketone (1) 1
gak, cyclin g-associated kinase (1) 1
gsk3, glycogen synthase kinase 3 (1) 1
gst, glutathione s-transferase (1) 1
gst, glutathione transferase (1) 1
hek-293 cells, human embryonic kidney 293 cells (1) 1
hek-293 cells, human embryonic kidney-293 cells (1) 1
hipk, homeodomain-interacting protein kinase (1) 1
his6, hexahistidine (1) 1
ieg (1) 1
igf-1, insulin-like growth factor-1 (1) 1
ikk, inhibitory κb kinase (1) 1
il-1, interleukin 1 (1) 1
immediate early gene (1) 1
inducible transcription factor (1) 1
inhibitor specificity (1) 1
itf (1) 1
jnk, c-jun n-terminal kinase (1) 1
kinase profiling (1) 1
lck, lymphocyte cell-specific protein-tyrosine kinase (1) 1
long-term potentiation (1) 1
lps, lipopolysaccharide (1) 1
ltp (1) 1
maldi–tof, matrix-assisted laser-desorption ionization–time of flight (1) 1
mapk (1) 1
mapk-activated protein kinase (1) 1
mapkap-k (1) 1
mark, microtubule-affinity-regulating kinase (1) 1
mbp, myelin basic protein (1) 1
mef, mouse embryonic fibroblast (1) 1
melk, maternal embryonic leucine-zipper kinase (1) 1
mitogen- and stress-activated protein kinase (1) 1
mitogen-activated protein kinase (1) 1
mitogen-activated protein kinase 1 - metabolism (1) 1
mitogen-activated protein kinase 3 - metabolism (1) 1
mitogen-activated protein kinases - antagonists & inhibitors (1) 1
mitogen-activated protein kinases - metabolism (1) 1
mitogens (1) 1
mkk1, mapk kinase-1 (1) 1
mms, methyl methanesulfonate (1) 1
mnk, mapk-integrating protein kinase (1) 1
molecular sequence data (1) 1
msk2 (1) 1
mst, mammalian homologue ste20-like kinase (1) 1
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Biochemical journal, ISSN 1470-8728, 12/2007, Volume 408, Issue 3, pp. 297 - 315
The specificities of 65 compounds reported to be relatively specific inhibitors of protein kinases have been profiled against a panel of 70-80 protein kinases... 
Drug discovery | Kinase profiling | Protein kinase | Anti-cancer drugs | Inhibitor specificity | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Amino Acid Sequence | Cell Line | Phosphorylation | Recombinant Proteins - antagonists & inhibitors | Animals | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Humans | Drug Design | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | Mitogen-Activated Protein Kinases - metabolism | Spodoptera | Index Medicus | Yes1, Yamaguchi sarcoma viral oncogene homologue 1 | CSK, C-terminal Src kinase | Lck, lymphocyte cell-specific protein-tyrosine kinase | EGF, epidermal growth factor | FGF-R, fibroblast-growth-factor receptor | PAK, p21-activated protein kinase | PDK, 3-phosphoinositide-dependent protein kinase | PI3K, phosphatidylinositol (phosphoinositide) 3-kinase | NEK, NIMA (never in mitosis in Aspergillus nidulans)-related kinase | RSK, p90 ribosomal S6 kinase | HEK-293 cells, human embryonic kidney-293 cells | VEGF, vascular endothelial growth factor (vasoendothelial growth factor) | EF2K, elongation-factor-2 kinase | CK, casein kinase | PTEN, phosphatase and tensin homologue deleted on chromosome 10 | ERK, extracellular-signal-regulated kinase | ATM, ataxia telangiectasia mutated | drug discovery | SRPK, serine-arginine protein kinase | IL-1, interleukin 1 | MNK, MAPK-integrating protein kinase | ROCK, Rho-dependent protein kinase | CaMKK, CaMK kinase | GST, glutathione transferase | MKK1, MAPK kinase-1 (also called MEK1, MAPK or ERK kinase 1) | GAK, cyclin G-associated kinase | inhibitor specificity | FMK, fluoromethylketone | MST, mammalian homologue Ste20-like kinase | PKA, cAMP-dependent protein kinase | FKBP, FK506-binding protein | PPAR, peroxisome-proliferator-activated receptor | IKK, inhibitory κB kinase | PH, pleckstrin homology | MBP, myelin basic protein | AICAR, aminoimidazole-4-carboxamide-1-β-D-ribofuranoside | MAPKAP-K, MAPK-activated protein kinase | Sf21, Spodoptera frugiperda (fall armyworm) 21 | MARK, microtubule-affinity-regulating kinase | PIM, provirus integration site for Moloney murine leukaemia virus | LPS, lipopolysaccharide | MSK, mitogen- and stress-activated protein kinase | anti-cancer drugs | MAPK, mitogen-activated protein kinase | MELK, maternal embryonic leucine-zipper kinase | His6, hexahistidine | CAK, cyclin-dependent kinase-activating kinase | Eph-A2, Ephrin A2 receptor | PLK, polo-like kinase | ATF2, activating transcription factor 2 | PKD, protein kinase D | Src, sarcoma kinase | AMPK, AMP-activated protein kinase | MMS, methyl methanesulfonate | CHK, checkpoint kinase | JNK, c-Jun N-terminal kinase | TORC1, mTOR (mammalian target of rapamycin)–raptor (regulatory associated protein of mTOR) complex | protein kinase | BRSK, brain-specific kinase | RIP2, receptor-interacting protein 2 | kinase profiling | IGF-1, insulin-like growth factor-1 | S6K1, S6 kinase 1 | DYRK, dual-specificity tyrosine-phosphorylated and -regulated kinase | HIPK, homeodomain-interacting protein kinase | ZMP, aminoimidazole-4-carboxamide-1-β-D-ribofuranoside monophosphate | PRAK, p38-regulated activated kinase | PKC, protein kinase C | Src-I1, Src inhibitor 1 | TANK, TRAF (tumour-necrosis-factor-receptor-associated factor)-family-member-associated nuclear factor κB activator | NFAT, nuclear factor for activated T-cells | PHK, phosphorylase kinase | GSK3, glycogen synthase kinase 3 | PKB, protein kinase B (also called Akt) | CaMK, calmodulin-dependent kinase | CDK, cyclin-dependent protein kinase | NDRG, N-myc downstream-regulated gene | SmMLCK, smooth-muscle myosin light-chain kinase | TBK1, TANK-binding kinase 1 | PRK, protein kinase C-related kinase | SGK, serum- and glucocorticoid-induced kinase
Journal Article
Biochemical journal, ISSN 0264-6021, 04/2005, Volume 387, Issue 2, pp. 507 - 517
MSK1 (mitogen- and stress-activated protein kinase) is a kinase activated in cells downstream of both the ERK1/2... 
MSK2 | Mitogen- and stress-activated protein kinase (MSK1) | 3-Phosphoinositide-dependent protein kinase 1 (PDK1) | P38 | Extracellular-signal-regulated kinase (ERK) | P90 ribosomal S6 kinase (RSK) | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Amino Acid Sequence | Cell Line | Phosphorylation | Mutagenesis, Site-Directed | Humans | Molecular Sequence Data | Ribosomal Protein S6 Kinases, 90-kDa - chemistry | Ribosomal Protein S6 Kinases, 90-kDa - metabolism | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Enzyme Activation | Mitogens | Mitogen-Activated Protein Kinase 1 - metabolism | Index Medicus | mitogen- and stress-activated protein kinase (MSK1) | 3-phosphoinositide-dependent protein kinase 1 (PDK1) | PDK1, 3-phosphoinositide-dependent protein kinase 1 | GST, glutathione S-transferase | HEK-293 cells, human embryonic kidney 293 cells | RSK, p90 ribosomal S6 kinase | extracellular-signal-regulated kinase (ERK) | ERK, extracellular-signal-regulated kinase | MALDI–TOF, matrix-assisted laser-desorption ionization–time of flight | PEI, polyethyleneimine | p38 | DMEM, Dulbecco's modified Eagle's medium | MAPKAP-K, MAPK-activated protein kinase | MEF, mouse embryonic fibroblast | PH domain, pleckstrin homology domain | MSK, mitogen- and stress-activated protein kinase | p90 ribosomal S6 kinase (RSK) | PIP3, phosphatidylinositol 3,4,5-trisphosphate | MAPK, mitogen-activated protein kinase | PKA, PKB, PKC and PKG, protein kinases A, B, C and G respectively | TFA, trifluoroacetic acid
Journal Article
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