X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (58) 58
phosphorylation (50) 50
humans (47) 47
animals (39) 39
protein-serine-threonine kinases - metabolism (37) 37
mark (33) 33
biochemistry & molecular biology (31) 31
mark/par-1 (28) 28
protein-serine-threonine kinases - genetics (27) 27
polarity (20) 20
alzheimers-disease (17) 17
cell biology (16) 16
tau (16) 16
alzheimer's disease (15) 15
neurosciences (15) 15
par-1 (14) 14
tau proteins - metabolism (14) 14
microtubule-associated proteins (13) 13
amino acid sequence (12) 12
mice (12) 12
microtubules (12) 12
kinases (11) 11
molecular sequence data (11) 11
protein-kinase (11) 11
rats (11) 11
alzheimer disease - metabolism (10) 10
cell line (10) 10
cytoskeleton (10) 10
kinase (10) 10
signal transduction (10) 10
cancer (9) 9
cell polarity (9) 9
establishment (9) 9
microtubules - metabolism (9) 9
protein kinases (9) 9
proteins (9) 9
analysis (8) 8
family (8) 8
lkb1 (8) 8
models, molecular (8) 8
protein (8) 8
protein binding (8) 8
protein-serine-threonine kinases - chemistry (8) 8
tau-protein (8) 8
ubiquitin-associated domains (8) 8
affinity-regulating kinase (7) 7
ampk (7) 7
cells (7) 7
cells, cultured (7) 7
drosophila (7) 7
female (7) 7
hek293 cells (7) 7
localization (7) 7
male (7) 7
microtubule (7) 7
mutation (7) 7
neurons (7) 7
protein-serine-threonine kinases - antagonists & inhibitors (7) 7
protein-serine-threonine kinases - physiology (7) 7
activated protein-kinase (6) 6
activation (6) 6
alzheimer’s disease (6) 6
article (6) 6
binding sites (6) 6
biophysics (6) 6
brain (6) 6
enzyme activation (6) 6
gene expression (6) 6
life sciences (6) 6
microtubule-associated proteins - metabolism (6) 6
recombinant proteins - metabolism (6) 6
research article (6) 6
substrate specificity (6) 6
alzheimer disease - drug therapy (5) 5
ampk, amp-activated protein kinase (5) 5
binding (5) 5
cell differentiation (5) 5
cho cells (5) 5
cricetinae (5) 5
crystallography, x-ray (5) 5
gene (5) 5
growth (5) 5
mark2 (5) 5
neurodegeneration (5) 5
neurofibrillary tangles (5) 5
paired helical filaments (5) 5
protein kinases - metabolism (5) 5
sequence homology, amino acid (5) 5
serine (5) 5
tau protein (5) 5
alzheimer disease (4) 4
alzheimer disease - pathology (4) 4
amp-activated protein kinase (4) 4
amp-activated protein kinases - metabolism (4) 4
brain - metabolism (4) 4
brsk, brain-specific kinase (4) 4
c-elegans par-1 (4) 4
catalytic domain (4) 4
chemistry, medicinal (4) 4
cloning (4) 4
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Journal Article
Journal Article
The Journal of endocrinology, ISSN 0022-0795, 5/2013, Volume 217, Issue 2, pp. R13 - R23
During spermatogenesis, spermatids derived from meiosis simultaneously undergo extensive morphological transformation, to become highly specialized and... 
Testis | microtubule | spermatogenesis | seminiferous epithelial cycle | spermiogenesis | spermatid adhesion | MARKs
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2008, Volume 283, Issue 27, pp. 18873 - 18882
MARK/Par-1, a kinase family with diverse functions particularly in inducing cell polarity, can phosphorylate microtubule-associated proteins in their repeat... 
TAU-PROTEIN | ALZHEIMER-LIKE STATE | PAR-1 | UBIQUITIN-ASSOCIATED DOMAINS | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MARK/PAR-1 | DISEASE | NEURONAL POLARITY | SAD KINASES | ESTABLISHMENT
Journal Article
Journal Article
Biochemical Journal, ISSN 0264-6021, 12/2007, Volume 408, Issue 3, pp. 297 - 315
The specificities of 65 compounds reported to be relatively specific inhibitors of protein kinases have been profiled against a panel of 70-80 protein kinases.... 
Drug discovery | Kinase profiling | Protein kinase | Anti-cancer drugs | Inhibitor specificity | RHO-ASSOCIATED KINASE | TUMOR PROGRESSION | FAMILY-MEMBERS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL-PROLIFERATION | protein kinase | P38 MAP KINASE | CYCLIN-DEPENDENT KINASES | RECEPTOR TYROSINE KINASES | drug discovery | kinase profiling | SB 203580 | anti-cancer drugs | ISOFORMS IN-VITRO | P90 RSK | inhibitor specificity | Amino Acid Sequence | Cell Line | Phosphorylation | Recombinant Proteins - antagonists & inhibitors | Animals | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Humans | Drug Design | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | Mitogen-Activated Protein Kinases - metabolism | Spodoptera | Index Medicus | Yes1, Yamaguchi sarcoma viral oncogene homologue 1 | CSK, C-terminal Src kinase | Lck, lymphocyte cell-specific protein-tyrosine kinase | EGF, epidermal growth factor | FGF-R, fibroblast-growth-factor receptor | PAK, p21-activated protein kinase | PDK, 3-phosphoinositide-dependent protein kinase | PI3K, phosphatidylinositol (phosphoinositide) 3-kinase | NEK, NIMA (never in mitosis in Aspergillus nidulans)-related kinase | RSK, p90 ribosomal S6 kinase | HEK-293 cells, human embryonic kidney-293 cells | VEGF, vascular endothelial growth factor (vasoendothelial growth factor) | EF2K, elongation-factor-2 kinase | CK, casein kinase | PTEN, phosphatase and tensin homologue deleted on chromosome 10 | ERK, extracellular-signal-regulated kinase | ATM, ataxia telangiectasia mutated | SRPK, serine-arginine protein kinase | IL-1, interleukin 1 | MNK, MAPK-integrating protein kinase | ROCK, Rho-dependent protein kinase | CaMKK, CaMK kinase | GST, glutathione transferase | MKK1, MAPK kinase-1 (also called MEK1, MAPK or ERK kinase 1) | GAK, cyclin G-associated kinase | FMK, fluoromethylketone | MST, mammalian homologue Ste20-like kinase | PKA, cAMP-dependent protein kinase | FKBP, FK506-binding protein | PPAR, peroxisome-proliferator-activated receptor | IKK, inhibitory κB kinase | PH, pleckstrin homology | MBP, myelin basic protein | AICAR, aminoimidazole-4-carboxamide-1-β-D-ribofuranoside | MAPKAP-K, MAPK-activated protein kinase | Sf21, Spodoptera frugiperda (fall armyworm) 21 | MARK, microtubule-affinity-regulating kinase | PIM, provirus integration site for Moloney murine leukaemia virus | LPS, lipopolysaccharide | MSK, mitogen- and stress-activated protein kinase | MAPK, mitogen-activated protein kinase | MELK, maternal embryonic leucine-zipper kinase | His6, hexahistidine | CAK, cyclin-dependent kinase-activating kinase | Eph-A2, Ephrin A2 receptor | PLK, polo-like kinase | ATF2, activating transcription factor 2 | PKD, protein kinase D | Src, sarcoma kinase | AMPK, AMP-activated protein kinase | MMS, methyl methanesulfonate | CHK, checkpoint kinase | JNK, c-Jun N-terminal kinase | TORC1, mTOR (mammalian target of rapamycin)–raptor (regulatory associated protein of mTOR) complex | BRSK, brain-specific kinase | RIP2, receptor-interacting protein 2 | IGF-1, insulin-like growth factor-1 | S6K1, S6 kinase 1 | DYRK, dual-specificity tyrosine-phosphorylated and -regulated kinase | HIPK, homeodomain-interacting protein kinase | ZMP, aminoimidazole-4-carboxamide-1-β-D-ribofuranoside monophosphate | PRAK, p38-regulated activated kinase | PKC, protein kinase C | Src-I1, Src inhibitor 1 | TANK, TRAF (tumour-necrosis-factor-receptor-associated factor)-family-member-associated nuclear factor κB activator | NFAT, nuclear factor for activated T-cells | PHK, phosphorylase kinase | GSK3, glycogen synthase kinase 3 | PKB, protein kinase B (also called Akt) | CaMK, calmodulin-dependent kinase | CDK, cyclin-dependent protein kinase | NDRG, N-myc downstream-regulated gene | SmMLCK, smooth-muscle myosin light-chain kinase | TBK1, TANK-binding kinase 1 | PRK, protein kinase C-related kinase | SGK, serum- and glucocorticoid-induced kinase
Journal Article
Biochemical Journal, ISSN 0264-6021, 04/2010, Volume 427, Issue 1, pp. 69 - 78
More than 200 phosphorylated 14-3-3-binding sites in the literature were analysed to define 14-3-3 specificities, identify relevant protein kinases, and give... 
Evolution | 14-3-3 protein | Disrupted-in-schizophrenia 1 (DISC1) | calmodulin-dependent protein kinase | AGC protein kinase | NEURONAL MIGRATION | SIGNALING PATHWAYS | MEMBRANE H+-ATPASE | REGULATING 14-3-3 BINDING | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | EUKARYOTIC PROTEIN-KINASES | evolution | NUCLEAR-LOCALIZATION | EXOENZYME-S | STRUCTURAL BASIS | Ca2+/calmodulin-dependent protein kinase | disrupted-in-schizophrenia 1 (DISC1) | ENDOPLASMIC-RETICULUM | Protein Kinases - metabolism | Phosphorylation | Immunoprecipitation | Humans | RNA, Messenger - genetics | Cells, Cultured | Computational Biology | Kidney - cytology | RNA, Messenger - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | 14-3-3 Proteins - metabolism | Nerve Tissue Proteins - metabolism | Kidney - metabolism | Carrier Proteins - metabolism | Protein Binding | Binding Sites | Dimerization | Calcium-Calmodulin-Dependent Protein Kinases - metabolism | 14-3-3 Proteins - genetics | Index Medicus | Bcl-2-associated death promoter | AANAT, serotonin acetyltransferase | FOXO, Forkhead box O | KLC, kinesin light chain | CDK5, cyclin-dependent kinase 5 | HEK, human embryonic kidney | MARK, microtubule affinity-regulating kinase | AMPK, AMP-activated protein kinase | EST, expressed sequence tag | PKB, protein kinase B | RSK, ribosomal S6 kinase | CaMK, Ca2 | GLUT4, glucose transporter 4 | protein kinase G | GST, glutathione transferase | HDAC, histone deacetylase | HAP1A, Huntingtin-associated protein 1A | DIG, digoxigenin | PKC, protein kinase C | BAD, Bcl-XL | PP2A, protein phosphatase 2A | DSTT, Division of Signal Transduction Therapy | HA, haemagglutinin | AGC, protein kinase A | Ca2 | PI4K, phosphoinositide 4-kinase | DISC1, disrupted-in-schizophrenia 1 | protein kinase C family kinase | YAP1, yes-associated protein 1
Journal Article