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Biochemical and Biophysical Research Communications, ISSN 0006-291X, 03/2008, Volume 367, Issue 4, pp. 906 - 911
Mutations in mitochondrial DNA have been associated with cardiovascular disease. We report here the clinical, genetic, and molecular characterization of one... 
Hypertension | Chinese | Mitochondrial DNA | Mutation | Maternally inherited | tRNA metabolism
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 2008, Volume 367, Issue 4, pp. 906 - 911
Mutations in mitochondrial DNA have been associated with cardiovascular disease. We report here the clinical, genetic, and molecular characterization of one... 
Hypertension | Chinese | Mitochondrial DNA | Mutation | tRNA metabolism | Maternally inherited
Journal Article
by Jiang, PP and Wang, M and Xue, L and Xiao, Y and Yu, JL and Wang, H and Yao, J and Liu, H and Peng, YY and Liu, HQ and Li, HY and Chen, Y and Guan, MX
MOLECULAR AND CELLULAR BIOLOGY, ISSN 0270-7306, 07/2016, Volume 36, Issue 14, pp. 1920 - 1930
In this report, we investigated the pathophysiology of a novel hypertension-associated mitochondrial tRNA(Ala) 5655A -> G (m.5655A -> G) mutation. The... 
MATERNALLY INHERITED HYPERTENSION | DNA MUTATION | SUPEROXIDE-PRODUCTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISEASE | HAN CHINESE FAMILIES | DEAFNESS | HEREDITARY OPTIC NEUROPATHY | HEALTH | IDENTIFICATION | 4435A-GREATER-THAN-G MUTATION | CELL BIOLOGY
Journal Article
by Li, HY and Geng, JW and Yu, H and Tang, XW and Yang, XJ and Xue, L
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ISSN 0006-291X, 01/2018, Volume 495, Issue 1, pp. 574 - 581
Mitochondrial DNA mutations are one of the molecular genetic bases of hypertension. Here, we performed clinical, genetic and mutational evaluation, molecular... 
Hypertension | PHYLOGENY | DNA MUTATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | FAMILY | MATERNALLY INHERITED HYPERTENSION | DISEASES | BIOPHYSICS | METABOLISM | Chinese Han | TRNA(MET) | DEAFNESS | Mutation | HEREDITARY OPTIC NEUROPATHY | TRANSFER-RNA | Mitochondrial tRNA
Journal Article
by Chen, X and He, XY and Zhu, C and Zhang, YS and Li, ZB and Liu, YQ and Zhang, YX and Yin, T and Li, Y
BMC MEDICAL GENETICS, ISSN 1471-2350, 07/2019, Volume 20, Issue 1, pp. 121 - 7
BackgroundThe mitochondrial genotype 5178 cytosine/adenine (5178 C>A) within the NADH dehydrogenase subunit-2 gene (ND2) was proved to associate with longevity... 
Hypertension | TRNA(ILE) | Interaction | ALCOHOL-CONSUMPTION | PREVALENCE | NADH dehydrogenase subunit 2 | BLOOD-PRESSURE | MATERNALLY INHERITED HYPERTENSION | Mitochondria | METABOLISM | DNA | MUTATION | GENETICS & HEREDITY | A/C POLYMORPHISM | Variation | ASSOCIATION | NAD (Coenzyme) | Genetic aspects | Research | Genetic susceptibility | Medicine, Experimental | Medical research | Risk factors
Journal Article
by Wang, L and Dong, ZB and Lin, WH and Gao, RR and Chen, CM and Xu, JZ
MOLECULAR MEDICINE REPORTS, ISSN 1791-2997, 11/2017, Volume 16, Issue 5, pp. 6029 - 6033
Mitochondrial DNA mutations have been reported to be associated with essential hypertension. The present study reported the clinical and molecular features of... 
MEDICINE, RESEARCH & EXPERIMENTAL | Chinese family | essential hypertension | IDENTIFICATION | COMPLETE NUCLEOTIDE-SEQUENCE | GENOME | MATERNALLY INHERITED HYPERTENSION | ONCOLOGY | DNA | DISEASE | TRNA(MET) | mitochondrial | T4363C mutation | transfer RNA(Gln)
Journal Article
by Jia, ZD and Zhang, Y and Li, Q and Ye, ZZ and Liu, YQ and Fu, CZ and Cang, XH and Wang, M and Guan, MX
NUCLEIC ACIDS RESEARCH, ISSN 0305-1048, 02/2019, Volume 47, Issue 4, pp. 2056 - 2074
The tissue specificity of mitochondrial tRNA mutations remains largely elusive. In this study, we demonstrated the deleterious effects of tRNA(Thr) 15927G>A... 
MATERNALLY INHERITED HYPERTENSION | PHENOTYPIC MANIFESTATION | COMPLEX I | DNA MUTATION | OXIDATIVE STRESS | MG37 MODIFICATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | 12S RIBOSOMAL-RNA | BIOCHEMICAL-EVIDENCE | NUCLEAR MODIFIER | 4435A-GREATER-THAN-G MUTATION
Journal Article
by Yu, SS and Du, JM and Tang, ZD and He, ZF
MOLECULAR MEDICINE REPORTS, ISSN 1791-2997, 04/2017, Volume 15, Issue 4, pp. 1832 - 1836
Mutations in mitochondrial (mt) transfer (t) RNA (mt-tRNA) have been reported to serve important roles in hypertension. To determine the underlying molecular... 
MEDICINE, RESEARCH & EXPERIMENTAL | Chinese family | A4401G | CARDIOMYOPATHY | COMPLETE NUCLEOTIDE-SEQUENCE | GENOME | MATERNALLY INHERITED HYPERTENSION | GENE | ONCOLOGY | G5821A | DNA | transfer RNA mutation | hypertension
Journal Article
by Xu, YH and Chen, XM and Huang, HL and Liu, WT
INTERNATIONAL HEART JOURNAL, ISSN 1349-2365, 01/2017, Volume 58, Issue 1, pp. 95 - 99
Mutations in mitochondrial DNA are associated with the pathogenesis of essential hypertension. We report here the clinical, genetic, and molecular... 
MATERNALLY INHERITED HYPERTENSION | PATHOGENESIS | Variants | TRANSFER-RNA MUTATIONS | CARDIAC & CARDIOVASCULAR SYSTEMS | Pedigree | DNA | DISEASE | T7511C MUTATION | Blood pressure | DEAFNESS | mt-tRNA
Journal Article
by Yin, S.L and Lan, C and Pei, H and Zhu, Z.Q
Genetics and Molecular Research, ISSN 1676-5680, 12/2015, Volume 14, Issue 4, pp. 17692 - 17698
Journal Article
by Lu, Y and Xiao, TH and Zhang, F and Chen, YM and Liu, YQ and Li, Y and Chen, YD and Li, ZB and Guan, MX
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ISSN 0006-291X, 11/2014, Volume 454, Issue 4, pp. 500 - 504
Journal Article
Current Opinion in Cardiology, ISSN 0268-4705, 05/2017, Volume 32, Issue 3, pp. 267 - 274
Journal Article
by Liu, YQ and Li, Y and Gao, JL and Zhu, C and Lan, YF and Yang, J and Li, ZB and Guan, MX and Chen, YD
BMC MEDICAL GENETICS, ISSN 1471-2350, 07/2014, Volume 15
Background: Hypertension is a very common cardiovascular disease influenced by multiple genetic and environmental factors. More recently, there are some... 
Hypertension | tRNA | PREVENTION | JOINT NATIONAL COMMITTEE | GENOME | MATERNALLY INHERITED HYPERTENSION | ORGANIZATION | Mitochondria | DNA | SEQUENCE | DISEASE | GENETICS & HEREDITY | Mutation | HIGH BLOOD-PRESSURE
Journal Article
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