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NUCLEIC ACIDS RESEARCH, ISSN 0305-1048, 08/2019, Volume 47, Issue 14, pp. 7247 - 7261
Scaffold/matrix attachment regions (S/MARs) are DNA elements that serve to compartmentalize the chromatin into structural and functional domains. These... 
ORGANIZATION | DNA-BINDING | SMAR1 | NUCLEAR-MATRIX | CHROMATIN LOOPS | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | GENE-EXPRESSION | MUTANT P53 | INCREASE TRANSGENE EXPRESSION | CANCER | Computational Biology
Journal Article
Scientific Reports, ISSN 2045-2322, 05/2016, Volume 6, Issue 1, p. 26446
We previously demonstrated that the characteristic sequence of matrix attachment regions (MARs) allows transgenes to be maintained episomally in CHO cells. In... 
CHO-CELL LINES | ELEMENT | HUMAN GENOME | REPLICATION | NUCLEAR-MATRIX | TRANSGENE EXPRESSION | NONVIRAL VECTOR | DNA | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | MITOTIC STABILITY | Ubiquitin | Cell culture | Cytomegalovirus | Transfection | Sarcoma | Matrix attachment regions | Phosphoglycerate kinase | Transgenes | Promoters | Expression vectors
Journal Article
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 02/2017, Volume 7, Issue 1, p. 42805
Matrix attachment regions (MARs) are cis-acting DNA elements that can increase transgene expression levels in a CHO cell expression system. To investigate the... 
ELEMENTS | SOMATIC MAMMALIAN-CELLS | IMPACT | RECOMBINANT PROTEINS | MULTIDISCIPLINARY SCIENCES | DIFFERENT PROMOTERS | HIGH PRODUCER | GENE-EXPRESSION | CHO-CELLS | LEVEL | LINES | Flow cytometry | Cytomegalovirus | Geneticin | Transfection | Green fluorescent protein | Matrix attachment regions | Interferon | Transgenes | Promoters | Deoxyribonucleic acid--DNA
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2012, Volume 7, Issue 7, p. e40617
In tumor progression definite alterations in nuclear matrix (NM) protein composition as well as in chromatin structure occur. The NM interacts with chromatin... 
ORGANIZATION | LAMIN SCAFFOLD | CHROMATIN LOOPS | SATB1 | PROGNOSIS | BIOLOGY | ARCHITECTURE | GENE-REGULATION | PROTEOMIC ANALYSIS | EXPRESSION | DOMAINS | Blotting, Southwestern | Prostatic Neoplasms - metabolism | Prostatic Neoplasms - pathology | Heterogeneous-Nuclear Ribonucleoprotein U - metabolism | Phosphorylation | Matrix Attachment Region Binding Proteins - metabolism | Humans | Nuclear Matrix-Associated Proteins - metabolism | Male | Blotting, Western | DNA, Neoplasm - chemistry | Lamin Type B - metabolism | Protein Transport | Poly(ADP-ribose) Polymerases - metabolism | Matrix Attachment Regions | Antibody Specificity - immunology | Base Sequence | Cell Line, Tumor | Protein Binding | Cell Differentiation | Nucleic Acid Conformation | RNA-Binding Proteins - metabolism | Chromatin | Analysis | Nucleotide sequencing | Binding proteins | Cell differentiation | Prostate cancer | Protein binding | DNA sequencing | Oxidative stress | Prostate carcinoma | Pathogenesis | Lung cancer | Differentiation (biology) | Genomes | Metastasis | ADP | Matrix methods | Carcinogenesis | Gene sequencing | Complexity | Proteins | Genotype & phenotype | Carcinogens | Protein composition | Ribose | Mathematical analysis | Cell cycle | Deoxyribonucleic acid--DNA | Phenotypes | Nucleotide sequence | Amino acid sequence | Poly(ADP-ribose) polymerase | Breast cancer | Gene expression | Laser microscopy | Polymerase | Androgens | Microscopy | Matrix attachment regions | Prostate | Cancer | Deoxyribonucleic acid | DNA
Journal Article
International Journal of Cancer, ISSN 0020-7136, 10/2015, Volume 137, Issue 7, pp. 1574 - 1586
Journal Article