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Annals of the Rheumatic Diseases, ISSN 0003-4967, 06/2018, Volume 77, Issue Suppl 2, p. 1326
BackgroundEarly diagnosis of rheumatoid arthritis (RA) is crucial but recognition of its disease activity and prognosis can help tailor treatment for patients... 
Stromelysin 1 | Cytokines | Matrix metalloproteinase | Patients | Synovial fluid | 14-3-3 protein | Rheumatoid arthritis | Biomarkers | Extracellular matrix | Amyloid | Metalloproteinase | Health risk assessment | Enzyme-linked immunosorbent assay | Regulatory proteins
Journal Article
Circulation Research, ISSN 0009-7330, 06/2001, Volume 88, Issue 12, pp. 1291 - 1298
Diabetes mellitus (DM) is a primary risk factor for cardiovascular disease. Although recent studies have demonstrated an important role for extracellular... 
Oxidative stress | Gelatinase | Remodeling | Atherosclerosis | Endothelium | atherosclerosis | endothelium | remodeling | PROTEIN-KINASE-C | CARDIAC & CARDIOVASCULAR SYSTEMS | COLONY-STIMULATING FACTOR | MECHANISM | ANGIOGENESIS | NECROSIS-FACTOR-ALPHA | IN-VITRO | ENDOTHELIAL-CELLS | gelatinase | PERIPHERAL VASCULAR DISEASE | DYSFUNCTION | HEMATOLOGY | EXPRESSION | oxidative stress | ADHESION MOLECULE-1 VCAM-1 | Endothelium, Vascular - cytology | Reactive Oxygen Species - metabolism | Muscle, Smooth, Vascular - metabolism | Diabetes Mellitus, Experimental - enzymology | Streptozocin | Oxidative Stress - physiology | Endothelium, Vascular - drug effects | Male | Insulin - blood | RNA, Messenger - metabolism | Matrix Metalloproteinase 9 - metabolism | Cattle | Matrix Metalloproteinase 9 - genetics | Aorta | Diabetes Mellitus, Experimental - chemically induced | Disease Models, Animal | Muscle, Smooth, Vascular - drug effects | Promoter Regions, Genetic | Matrix Metalloproteinase 2 - metabolism | Cells, Cultured | Enzyme Inhibitors - pharmacology | Rats | Blood Glucose | Glucose - pharmacology | Protein Kinase C - antagonists & inhibitors | Antioxidants - pharmacology | Macrophages - cytology | Muscle, Smooth, Vascular - cytology | Rats, Sprague-Dawley | Hyperglycemia - metabolism | Macrophages - metabolism | Animals | Endothelium, Vascular - metabolism | Glucose - metabolism | Macrophages - drug effects | Mice | Index Medicus
Journal Article
Journal Article
Journal Article
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 09/2013, Volume 67, pp. 325 - 334
Thirty-three 1,2,4-triazolo[1,5- ][1,3,5]triazin-5,7-dione and its 5-thioxo analogues were designed and synthesized which contained different substituents at -... 
1,2,4-Triazolo[1,5-a][1,3,5]triazine | Mixed-type inhibition | Breast cancer | Anti-angiogenesis | SAR | Thymidine phosphorylase inhibitors | BREAST-CARCINOMA | 3-AMINO-1,2,4-TRIAZOLES | CHEMISTRY, MEDICINAL | TUMOR ANGIOGENESIS | CANCER | NUCLEOSIDE DERIVATIVES | INHIBITORS | EXPRESSION | ENDOTHELIAL GROWTH-FACTOR | Triazoles - chemistry | Vascular Endothelial Growth Factors - antagonists & inhibitors | Humans | Structure-Activity Relationship | Enzyme Inhibitors - chemical synthesis | Dose-Response Relationship, Drug | Matrix Metalloproteinase 9 - metabolism | Enzyme Inhibitors - chemistry | Biomarkers, Tumor - metabolism | Triazines - chemistry | Triazoles - chemical synthesis | Molecular Structure | Biomarkers, Tumor - antagonists & inhibitors | Angiogenesis Inhibitors - chemical synthesis | Thymidine Phosphorylase - antagonists & inhibitors | Matrix Metalloproteinase 9 - biosynthesis | Triazines - pharmacology | Enzyme Inhibitors - pharmacology | Angiogenesis Inhibitors - pharmacology | Triazoles - pharmacology | Triazines - chemical synthesis | Vascular Endothelial Growth Factors - biosynthesis | Cell Line, Tumor | Vascular Endothelial Growth Factors - metabolism | Kinetics | Thymidine Phosphorylase - metabolism | Biomarkers, Tumor - biosynthesis | Angiogenesis Inhibitors - chemistry | Antimitotic agents | Drugstores | Antineoplastic agents | Vascular endothelial growth factor | Index Medicus
Journal Article
Journal Article
2012, 1. Aufl., EXS, ISBN 303480363X, Volume no. 103., x, 285
Matrix metalloproteinases (MMPs) are proteolytic enzymes that are involved in many physiological and pathological processes. The field of MMP research is very... 
Metalloproteinases | Inhibitors | Biology, life sciences | Pharmacology
Book
Journal Article
Neuron, ISSN 0896-6273, 10/2012, Volume 76, Issue 2, pp. 396 - 409
Adhesive contact between pre- and postsynaptic neurons initiates synapse formation during brain development and provides a natural means of transsynaptic... 
RELEASE PROBABILITY | AMPA RECEPTORS | TISSUE-PLASMINOGEN ACTIVATOR | NMDA RECEPTORS | VISUAL-CORTEX | MATRIX-METALLOPROTEINASE | CELL-ADHESION MOLECULES | LONG-TERM POTENTIATION | NEUROSCIENCES | INHIBITORY SYNAPSE FORMATION | PLASTICITY | Electric Stimulation | Synaptic Transmission - genetics | Dark Adaptation - genetics | Status Epilepticus - chemically induced | Dendrites - ultrastructure | Green Fluorescent Proteins - genetics | Pilocarpine - toxicity | Matrix Metalloproteinase 9 - metabolism | Muscarinic Agonists - toxicity | Excitatory Amino Acid Agents - pharmacology | Synaptic Transmission - drug effects | Excitatory Postsynaptic Potentials - genetics | Organ Culture Techniques | Disease Models, Animal | Animals, Newborn | Glutamic Acid - pharmacology | Enzyme Inhibitors - pharmacology | Mice, Transgenic | Signal Transduction - genetics | Mutation - genetics | Cell Adhesion Molecules, Neuronal - genetics | Microscopy, Confocal | Patch-Clamp Techniques | Signal Transduction - drug effects | Luminescent Proteins - genetics | Mice | Synaptic Transmission - physiology | Cercopithecus aethiops | Neurons - cytology | Threonine - metabolism | Cerebral Cortex - cytology | Excitatory Postsynaptic Potentials - drug effects | Transfection | Potassium Chloride - pharmacology | Threonine - genetics | Neurons - physiology | Female | Cell Adhesion Molecules, Neuronal - metabolism | Neurons - drug effects | Plant Lectins - genetics | Dendrites - metabolism | Biotinylation | Vesicular Glutamate Transport Protein 1 - metabolism | Mice, Inbred C57BL | Cells, Cultured | Electroporation | Photons | Hippocampus - cytology | Pregnancy | Animals | Neural Cell Adhesion Molecules - metabolism | Quaternary Ammonium Compounds - metabolism | Signal Transduction - physiology | Plant Lectins - metabolism | Pyridinium Compounds - metabolism | Luminescent Proteins - metabolism | Methyl aspartate | Neurons | Neurosciences | Proteins | Studies | Brain | Autism | Net losses | Kinases | Index Medicus | Adhesives
Journal Article