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Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 4974 - 18
Compact myelin comprises most of the dry weight of myelin, and its insulative nature is the basis for saltatory conduction of nerve impulses. The major dense... 
MULTIPLE-SCLEROSIS | ACTIN | MACROMOLECULES | LIPID VESICLES | MULTIDISCIPLINARY SCIENCES | ALTERED PEPTIDE LIGAND | DYNAMICS | MBP | MODEL | PLASMA-MEMBRANE | REVEALS | Proteins | Atomic force microscopy | Nerve conduction | Lipid membranes | Myelination | Multiple sclerosis | Demyelinating diseases | Neutron scattering | Demyelination | Electron microscopy | Sclerosis | Myelin basic protein | Index Medicus | Life Sciences
Journal Article
Proteins: Structure, Function, and Bioinformatics, ISSN 0887-3585, 07/2017, Volume 85, Issue 7, pp. 1336 - 1350
The molecular details of the association between the human Fyn‐SH3 domain, and the fragment of 18.5‐kDa myelin basic protein (MBP) spanning residues S38–S107... 
molecular recognition fragment (MoRF) | poly‐proline type II (PPII) | Fyn‐SH3 | amphipathic α‐helix | myelin basic protein (MBP) | intrinsically disordered protein (IDP) | molecular dynamics (MD) simulations | GROMACS | amphipathic α-helix | poly-proline type II (PPII) | Fyn-SH3 | BIOCHEMISTRY & MOLECULAR BIOLOGY | IMMUNODOMINANT EPITOPE | POSTTRANSLATIONAL MODIFICATIONS | amphipathic -helix | AZE AZETIDINE-2-CARBOXYLIC ACID | INTRINSICALLY DISORDERED PROTEINS | FYN TYROSINE KINASE | BIOPHYSICS | MULTIPLE-SCLEROSIS | CRK N-SH3 DOMAIN | STATE NMR-SPECTROSCOPY | CENTRAL-NERVOUS-SYSTEM | MESSENGER-RNA TRANSPORT | Protein Structure, Tertiary | Amino Acid Sequence | Protein Conformation, alpha-Helical | Peptides - chemistry | Humans | Phosphorylcholine - analogs & derivatives | Molecular Dynamics Simulation | Proline - chemistry | src Homology Domains | Thermodynamics | Animals | Protein Conformation, beta-Strand | Myelin Basic Protein - chemistry | Water - chemistry | Phosphorylcholine - chemistry | Protein Binding | Mice | Molecular Docking Simulation | Proto-Oncogene Proteins c-fyn - chemistry | Lipid Bilayers - chemistry | Binding Sites | Dimyristoylphosphatidylcholine - chemistry | Unithiol - chemistry | Molecular dynamics | Proline | Phospholipids | Myelin proteins | Proteins | Peptides | Myelin | Docking | Fuzzy | Myelin basic protein | Sheets | Fyn protein | Index Medicus
Journal Article
Brain, Behavior, and Immunity, ISSN 0889-1591, 2016, Volume 56, pp. 378 - 389
Highlights • MBP84-104 peptide, injected into an intact nerve, produces long-lasting pain. • IL-6 is the top-induced cytokine by MBP84-104, regardless of T... 
Psychiatry | Allergy and Immunology | Allodynia | Female pain | Gabapentin | Myelin | Adaptive immunity | T cells | Myelin basic protein | Chronic pain | Mechanical hypersensitivity | Neuropathic pain | Interleukin 6 | Cacna2d1 | Nude rat | Autoimmunity and pain | MBP | Interferon | DORSAL-ROOT GANGLIA | IMMUNOLOGY | PERIPHERAL-NERVE INJURY | CONSTRICTION INJURY | MECHANICAL PAIN HYPERSENSITIVITY | SCIATIC-NERVE | GENE-EXPRESSION | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | ALTERED PEPTIDE LIGAND | NEUROSCIENCES | SATELLITE GLIAL-CELLS | Hyperalgesia - chemically induced | Lidocaine - pharmacology | Spinal Cord - metabolism | Genomics | Peptide Fragments - pharmacology | Rats, Nude | Myelin Basic Protein - administration & dosage | Female | Myelin Basic Protein - pharmacology | Sciatic Nerve - drug effects | Interleukin-6 - metabolism | Peptide Fragments - administration & dosage | Rats | gamma-Aminobutyric Acid - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Calcium Channel Blockers - pharmacology | Rats, Sprague-Dawley | Cyclooxygenase Inhibitors - pharmacology | Animals | Hyperalgesia - drug therapy | Cyclohexanecarboxylic Acids - pharmacology | Interleukin-6 - immunology | Voltage-Gated Sodium Channel Blockers - pharmacology | Dizocilpine Maleate - pharmacology | Amines - pharmacology | Ketorolac - pharmacology | Index Medicus
Journal Article
Neuroscience Letters, ISSN 0304-3940, 05/2019, Volume 701, pp. 8 - 13
The myelin basic protein (MBP) gene is a complex gene which codes for several distinct forms of MBP. The various forms of MBP are functionally involved in the... 
Neuroprotection | Proteomic variation | Genetic variation | Myelin basic protein | Peromyscus leucopus | CELLS | ISOFORM | NEUROSCIENCES | CALCIUM INFLUX | GENE | PRODUCTS | MBP | LYME-DISEASE | EXPRESSION | Nervous system diseases | Analysis | Protein structure prediction | Mice | Information management | Single nucleotide polymorphisms | T cells | Myelin proteins | Neurophysiology
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 01/2018, Volume 143, pp. 621 - 631
Journal Article
Journal Article
Journal of Neuroscience Methods, ISSN 0165-0270, 01/2019, Volume 311, pp. 235 - 238
Objective of our work was to develop a sequential double nonfluorescent immunostaining method which allows the selective identification of myelinated motor... 
Nerve | Conduit | ChAT | MBP | Gap-lesion | Paraffin | Immunostaining | Biomaterials | SCIATIC-NERVE | REGENERATION | BIOCHEMICAL RESEARCH METHODS | NEUROSCIENCES | Viral antibodies | Antibodies | Choline | Myelin proteins
Journal Article
Journal of Neuroimmunology, ISSN 0165-5728, 2006, Volume 177, Issue 1, pp. 27 - 39
The pathogenic mechanisms that contribute to multiple sclerosis (MS) include leukocyte chemotaxis into the central nervous system (CNS) and the production of... 
Signaling | Multiple sclerosis | MBP | CXCL12 | Chemokines | signaling | multiple sclerosis | CHEMOKINE RECEPTOR CXCR4 | HUMAN-ENDOTHELIAL-CELLS | LYMPHOCYTE CHEMOATTRACTANT | FACTOR-I | IMMUNOLOGY | chemokines | CEREBROSPINAL-FLUID | VASCULAR ENDOTHELIUM | NEUROSCIENCES | AUTOIMMUNE ENCEPHALOMYELITIS | CELL-DERIVED FACTOR | NEURONAL CELLS | CENTRAL-NERVOUS-SYSTEM | Central Nervous System - metabolism | Wallerian Degeneration - pathology | Chemokine CCL2 - immunology | Humans | Middle Aged | Astrocytes - pathology | Central Nervous System - pathology | Male | MAP Kinase Signaling System - immunology | Central Nervous System - immunology | Myelin Sheath - metabolism | Astrocytes - immunology | Interleukin-1 - immunology | Aged, 80 and over | Adult | Female | Chemokine CCL2 - metabolism | Myelin Basic Protein - pharmacology | Interleukin-8 - metabolism | Macrophages - immunology | Multiple Sclerosis - metabolism | Chemokine CXCL12 | Interleukin-1 - metabolism | Myelin Basic Protein - metabolism | Myelin Sheath - immunology | Myelin Sheath - pathology | Wallerian Degeneration - metabolism | Cells, Cultured | Axons - metabolism | Receptors, CXCR4 - drug effects | Interleukin-1 - pharmacology | Myelin Basic Protein - immunology | Receptors, CXCR4 - metabolism | Wallerian Degeneration - immunology | Endothelial Cells - immunology | Macrophages - metabolism | MAP Kinase Signaling System - drug effects | Receptors, CXCR4 - immunology | Axons - pathology | Adolescent | Chemokines, CXC - metabolism | Multiple Sclerosis - immunology | Multiple Sclerosis - pathology | Axons - immunology | Chemotaxis, Leukocyte - immunology | Interleukin-8 - immunology | Chemokine CCL2 - drug effects | Astrocytes - metabolism | Brain damage | Macrophages | T cells | Neurons | Myelin proteins | Index Medicus
Journal Article