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Journal of Animal Science, ISSN 0021-8812, 12/2018, Volume 96, pp. 139 - 139
The whole-genome scanning may contribute the greater accuracy for the expected inbreeding level evaluation for using animals, which have a high estimated... 
Breeding | Melanocortin MC4 receptors | Genomes | Breeding of animals | Homozygosity | Progeny | Animals | Genotyping | Cattle | Pedigree | Quality control | Inbreeding | Mutation | Chromosomes
Journal Article
by Turcot, Valérie and Lu, Yingchang and Highland, Heather M and Schurmann, Claudia and Justice, Anne E and Fine, Rebecca S and Bradfield, Jonathan P and Esko, Tõnu and Giri, Ayush and Graff, Mariaelisa and Guo, Xiuqing and Hendricks, Audrey E and Karaderi, Tugce and Lempradl, Adelheid and Locke, Adam E and Mahajan, Anubha and Marouli, Eirini and Sivapalaratnam, Suthesh and Young, Kristin L and Alfred, Tamuno and Feitosa, Mary F and Masca, Nicholas G. D and Manning, Alisa K and Medina-Gomez, Carolina and Mudgal, Poorva and Ng, Maggie C. Y and Reiner, Alex P and Vedantam, Sailaja and Willems, Sara M and Winkler, Thomas W and Abecasis, Gonçalo and Aben, Katja K and Alam, Dewan S and Alharthi, Sameer E and Allison, Matthew and Amouyel, Philippe and Asselbergs, Folkert W and Auer, Paul L and Balkau, Beverley and Bang, Lia E and Barroso, Inês and Bastarache, Lisa and Benn, Marianne and Bergmann, Sven and Bielak, Lawrence F and Blüher, Matthias and Boehnke, Michael and Boeing, Heiner and Boerwinkle, Eric and Böger, Carsten A and Bork-Jensen, Jette and Bots, Michiel L and Bottinger, Erwin P and Bowden, Donald W and Brandslund, Ivan and Breen, Gerome and Brilliant, Murray H and Broer, Linda and Brumat, Marco and Burt, Amber A and Butterworth, Adam S and Campbell, Peter T and Cappellani, Stefania and Carey, David J and Catamo, Eulalia and Caulfield, Mark J and Chambers, John C and Chasman, Daniel I and Chen, Yii-Der I and Chowdhury, Rajiv and Christensen, Cramer and Chu, Audrey Y and Cocca, Massimiliano and Cook, James P and Corley, Janie and Corominas Galbany, Jordi and Cox, Amanda J and Crosslin, David S and Cuellar-Partida, Gabriel and D'Eustacchio, Angela and Danesh, John and Davies, Gail and Bakker, Paul I. W and Groot, Mark C. H and Mutsert, Renée and Deary, Ian J and Dedoussis, George and Demerath, Ellen W and Heijer, Martin and Hollander, Anneke I and Ruijter, Hester M and Dennis, Joe G and Denny, Josh C and Angelantonio, Emanuele and Drenos, Fotios and Du, Mengmeng and Dubé, Marie-Pierre and Dunning, Alison M and Easton, Douglas F and Edwards, Todd L and ... and Chd Exome Consortium and EPIC InterAct Consortium and Global Lipids Genetic Consortium and GoT2D Genes Consortium and MAGIC Investigators and Understanding Soc Sci Grp and ReproGen Consortium and Interval Study and Epic-Cvd Consortium and ExomeBP Consortium and T2D-Genes Consortium and INTERVAL Study and EPIC-CVD Consortium and EPIC InterAct Consortium and CHD Exome+ Consortium and Understanding Society Scientific Group and The MAGIC Investigators and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Enheten för biobanksforskning and Allmänmedicin and Umeå universitet and Medicin
Nature Genetics, ISSN 1061-4036, 01/2018, Volume 50, Issue 1, pp. 26 - 35
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 8157 - 13
Accumulating evidence has suggested that farnesoid X receptor (FXR) agonists, such as obeticholic acid (OCA) are therapeutically useful for non-alcoholic... 
Metabolic rate | Animal models | p53 Protein | Liver | Body weight | Melanocortin | Melanocortin MC4 receptors | Insulin | Steatosis | Cell activation | Fatty liver | Hepatocytes | Cell death | Rodents | Fibrosis | Bile
Journal Article
Psychopharmacology, ISSN 0033-3158, 9/2016, Volume 233, Issue 17, pp. 3269 - 3277
Anxiety disorders are the most common mental disorders in the USA. Characterized by feelings of uncontrollable apprehension, they are accompanied by physical,... 
Animal model | Neurosciences | Biomedicine | Depression | Anxiety | HPA axis | Pharmacology/Toxicology | Psychiatry | Neuropeptide | Stress | MC4 | CORTICOTROPIN-RELEASING HORMONE | SYSTEM | PSYCHIATRY | STRESS-INDUCED ANOREXIA | BEHAVIOR | IMMOBILIZATION STRESS | MC4 RECEPTOR | ELEVATED PLUS-MAZE | NEUROSCIENCES | BED NUCLEUS | FEMALE RATS | ETHANOL INTAKE | PHARMACOLOGY & PHARMACY | Hypothalamo-Hypophyseal System - drug effects | Receptors, Melanocortin - antagonists & inhibitors | Central Amygdaloid Nucleus - drug effects | Pituitary-Adrenal System - drug effects | Pituitary-Adrenal System - metabolism | Melanocyte-Stimulating Hormones - pharmacology | Rats | Male | Receptor, Melanocortin, Type 4 - metabolism | Basolateral Nuclear Complex - metabolism | Emotions - drug effects | Hypothalamo-Hypophyseal System - metabolism | Receptor, Melanocortin, Type 4 - drug effects | Animals | Anxiety Disorders | Neurotransmitter Agents - pharmacology | Pituitary Adenylate Cyclase-Activating Polypeptide - pharmacology | Behavior, Animal - drug effects | Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - metabolism | Central Amygdaloid Nucleus - metabolism | Corticosterone - blood | Basolateral Nuclear Complex - drug effects | Cell receptors | Polypeptides | Causes of | Physiological aspects | Health aspects | Amygdala (Brain) | Neuropeptides | Mental depression | Neuropsychology | Anxieties | anxiety | neuropeptide | depression | animal model
Journal Article
Molecular Neurobiology, ISSN 0893-7648, 2/2018, Volume 55, Issue 2, pp. 1396 - 1404
Journal Article
Molecular Neurobiology, ISSN 0893-7648, 6/2018, Volume 55, Issue 6, pp. 4984 - 4997
Journal Article
by Loos, Ruth J. F and Lindgren, Cecilia M and Li, Shengxu and Wheeler, Eleanor and Hua Zhao, Jing and Prokopenko, Inga and Inouye, Michael and Freathy, Rachel M and Attwood, Antony P and Beckmann, Jacques S and Berndt, Sonja I and Bergmann, Sven and Bennett, Amanda J and Bingham, Sheila A and Bochud, Murielle and Brown, Morris and Cauchi, Stéphane and Connell, John M and Cooper, Cyrus and Davey Smith, George and Day, Ian and Dina, Christian and De, Subhajyoti and Dermitzakis, Emmanouil T and Doney, Alex S. F and Elliott, Katherine S and Elliott, Paul and Evans, David M and Sadaf Farooqi, I and Froguel, Philippe and Ghori, Jilur and Groves, Christopher J and Gwilliam, Rhian and Hadley, David and Hall, Alistair S and Hattersley, Andrew T and Hebebrand, Johannes and Heid, Iris M and Herrera, Blanca and Hinney, Anke and Hunt, Sarah E and Jarvelin, Marjo-Riitta and Johnson, Toby and Jolley, Jennifer D. M and Karpe, Fredrik and Keniry, Andrew and Khaw, Kay-Tee and Luben, Robert N and Mangino, Massimo and Marchini, Jonathan and McArdle, Wendy L and McGinnis, Ralph and Meyre, David and Munroe, Patricia B and Morris, Andrew D and Ness, Andrew R and Neville, Matthew J and Nica, Alexandra C and Ong, Ken K and O'Rahilly, Stephen and Owen, Katharine R and Palmer, Colin N. A and Papadakis, Konstantinos and Potter, Simon and Pouta, Anneli and Qi, Lu and Randall, Joshua C and Rayner, Nigel W and Ring, Susan M and Sandhu, Manjinder S and Scherag, André and Sims, Matthew A and Song, Kijoung and Soranzo, Nicole and Speliotes, Elizabeth K and Syddall, Holly E and Teichmann, Sarah A and Timpson, Nicholas J and Tobias, Jonathan H and Uda, Manuela and Ganz Vogel, Carla I and Wallace, Chris and Waterworth, Dawn M and Weedon, Michael N and Willer, Cristen J and Wraight, Vicki L and Yuan, Xin and Zeggini, Eleftheria and Hirschhorn, Joel N and Strachan, David P and Ouwehand, Willem H and Caulfield, Mark J and Samani, Nilesh J and Frayling, Timothy M and Vollenweider, Peter and Waeber, Gerard and Mooser, Vincent and Deloukas, Panos and McCarthy, Mark I and Wareham, Nicholas J and ... and Diabetes Genetics Initiative and SardiNIA Study and FUSION and Prostate Lung Colorectal Ovarian and KORA and Wellcome Trust Case Control Consor and Nurses' Health Study and Wellcome Trust Case Control Consortium and Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial and The Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial and The Wellcome Trust Case Control Consortium and The SardiNIA Study and Diabetes - klinisk obesitasforskning and Genomik, diabetes och endokrinologi and Lund University and Genomics, Diabetes and Endocrinology and Diabetes - Clinical Obesity and Lunds universitet
Nature Genetics, ISSN 1061-4036, 06/2008, Volume 40, Issue 6, pp. 768 - 775
To identify common variants influencing body mass index (BMI), we analyzed genome-wide association data from 16,876 individuals of European descent. After... 
FTO GENE | GENETICS & HEREDITY | MELANOCORTIN-4 RECEPTOR GENE | EARLY-ONSET OBESITY | FRAMESHIFT MUTATION | DOMINANT | ADULT OBESITY | EXPRESSION | CHILDHOOD | DEFICIENCY | GENOME-WIDE ASSOCIATION | Meta-Analysis as Topic | Humans | Middle Aged | Alpha-Ketoglutarate-Dependent Dioxygenase FTO | Male | Body Weight - genetics | Obesity - genetics | Case-Control Studies | Genetic Variation | Proteins | Adult | Female | Child | Body Mass Index | Genetic Predisposition to Disease | Cross-Sectional Studies | Receptor, Melanocortin, Type 4 - genetics | Adiposity - genetics | Linkage Disequilibrium | Obesity - pathology | Randomized Controlled Trials as Topic | Obesity - epidemiology | Adolescent | Alleles | Aged | Polymorphism, Single Nucleotide | Chromosomes, Human, Pair 18 - genetics | Genome, Human | Quantitative Trait Loci | Cohort Studies | Obesity | Body mass index | Genetic variation | Physiological aspects | Genetic aspects | Diagnosis | Research | Risk factors | Medical research | Biomedical research | Body fat | Health services | Genetics | Birth weight | Adults | Progeny | Integration | Pedigree | Data processing | Melanocortin MC4 receptors | Single-nucleotide polymorphism | Children | Mutation | Population levels | Clinical Medicine | Näringslära | Hälsovetenskap | Endokrinologi och diabetes | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Nutrition and Dietetics | Endocrinology and Diabetes | Health Sciences
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Journal Article