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General and Comparative Endocrinology, ISSN 0016-6480, 12/2019, Volume 284, p. 113239
Neuropeptide Y (NPY) is the most powerful central neuropeptide implicated in feeding regulation via its receptors. Understanding the role of NPY system is... 
MC4R | Feeding regulation | NPY receptors | NPY | CART
Journal Article
Cell Metabolism, ISSN 1550-4131, 02/2019, Volume 29, Issue 2, pp. 488 - 500.e2
Obesity is a heterogeneous phenotype that is crudely measured by body mass index (BMI). There is a need for a more precise yet portable method of phenotyping... 
rare variants | MC4R | human genetics | metabolomics | health | obesity | polygenic risk scores | ANALYSIS REVEALS | PROFILE | GLUCOSE | MEN | ENDOCRINOLOGY & METABOLISM | RESISTANCE | BODY-MASS INDEX | METABOLICALLY HEALTHY | CORTISOL | CELL BIOLOGY | Obesity | Medical colleges | Metabolites | Health aspects | Epidemiology | Genomics
Journal Article
Endocrinology, ISSN 0013-7227, 09/2005, Volume 146, Issue 9, pp. 3739 - 3747
Journal Article
Trends in Molecular Medicine, ISSN 1471-4914, 02/2019, Volume 25, Issue 2, pp. 136 - 148
The melanocortin-4 receptor (MC4R) – embedded in the leptin–melanocortin pathway – is activated by proopiomelanocortin (POMC)-derived neuropeptides such as α-... 
MC4R | treatment | mutation | obesity | signalling | MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | Y GASTRIC BYPASS | PREVALENCE | INTRACELLULAR FREE CALCIUM | CELL BIOLOGY | SLEEVE GASTRECTOMY | GENE | BARIATRIC SURGERY | MC4R AGONIST | FRAMESHIFT MUTATION | METABOLIC-RATE
Journal Article
Medycyna Weterynaryjna, ISSN 0025-8628, 2019, Volume 75, Issue 1, pp. 50 - 53
The aim of the study was to analyze sexual activities of gilts representing various genotype groups in the RBP4 and MC4R locus. Observations of gilt behaviour... 
Mc4r gene | Sow sex activity | Gene polymorphism | Pulawy breed | MC4R | GENE | MC4R gene | gene polymorphism | VETERINARY SCIENCES | POLYMORPHISM | TRAITS | ASSOCIATION | sow sex activity
Journal Article
Nutrition, ISSN 0899-9007, 11/2019, Volume 67-68, p. 110547
Obesity is a multifactorial, complex, and public health problem worldwide. Interaction between genes and environment as associated with diet may predispose an... 
FTO | MC4R | Ghrelin | Leptin | Gene–diet interaction | CCK | Nutrigenetic
Journal Article
Cell metabolism, ISSN 1550-4131, 12/2013, Volume 18, Issue 6
The melanocortin receptor 4 (MC4R) is a well-established mediator of body weight homeostasis. However, the neurotransmitter(s) that mediate MC4R function... 
MC4R | feeding | energy expenditure | Sim1 | glutamate | obesity
Journal Article
by Morris, Andrew P and Voight, Benjamin F and Teslovich, Tanya M and Ferreira, Teresa and Segrè, Ayellet V and Steinthorsdottir, Valgerdur and Strawbridge, Rona J and Khan, Hassan and Grallert, Harald and Mahajan, Anubha and Prokopenko, Inga and Kang, Hyun Min and Dina, Christian and Esko, Tonu and Fraser, Ross M and Kanoni, Stavroula and Kumar, Ashish and Lagou, Vasiliki and Langenberg, Claudia and Luan, Jian'An and Lindgren, Cecilia M and Müller-Nurasyid, Martina and Pechlivanis, Sonali and Rayner, N. William and Scott, Laura J and Wiltshire, Steven and Yengo, Loic and Kinnunen, Leena and Rossin, Elizabeth J and Raychaudhuri, Soumya and Johnson, Andrew D and Dimas, Antigone S and Loos, Ruth J.F and Vedantam, Sailaja and Chen, Han and Florez, Jose C and Fox, Caroline and Liu, Ching-Ti and Rybin, Denis and Couper, David J and Kao, Wen Hong L and Li, Man and Cornelis, Marilyn C and Kraft, Peter and Sun, Qi and Van Dam, Rob M and Stringham, Heather M and Chines, Peter S and Fischer, Krista and Fontanillas, Pierre and Holmen, Oddgeir L and Hunt, Sarah E and Jackson, Anne U and Kong, Augustine and Lawrence, Robert and Meyer, Julia and Perry, John R.B and Platou, Carl G.P and Potter, Simon and Rehnberg, Emil and Robertson, Neil and Sivapalaratnam, Suthesh and Stančáková, Alena and Stirrups, Kathleen and Thorleifsson, Gudmar and Tikkanen, Emmi and Wood, Andrew R and Almgren, Peter and Atalay, Mustafa and Benediktsson, Rafn and Bonnycastle, Lori L and Burtt, Noël and Carey, Jason and Charpentier, Guillaume and Crenshaw, Andrew T and Doney, Alex S.F and Dorkhan, Mozhgan and Edkins, Sarah and Emilsson, Valur and Eury, Elodie and Forsen, Tom and Gertow, Karl and Gigante, Bruna and Grant, George B and Groves, Christopher J and Guiducci, Candace and Herder, Christian and Hreidarsson, Astradur B and Hui, Jennie and James, Alan and Jonsson, Anna and Rathmann, Wolfgang and Klopp, Norman and Kravic, Jasmina and Krjutškov, Kaarel and Langford, Cordelia and Leander, Karin and Lindholm, Eero and Lobbens, Stéphane and MäNnistö, Satu and ... and Meta-Anal Glucose Insulin-Related and Genetic Invest ANthropometric and Wellcome Trust Case Control and Asian Genetic Epidemiology and S Asian Type 2 Diabet SAT2D and DIAbet Genetics Replication and the DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium and Kardiovaskulär forskning - hypertoni and Cardiovascular Research - Hypertension and Lund University and Genomics, Diabetes and Endocrinology and Internmedicin - epidemiologi and EpiHealth: Epidemiology for Health and Genomik, diabetes och endokrinologi and Internal Medicine - Epidemiology and Lunds universitet and EXODIAB: Excellence in Diabetes Research in Sweden
Nature Genetics, ISSN 1061-4036, 09/2012, Volume 44, Issue 9, pp. 981 - 990
Journal Article
Small Ruminant Research, ISSN 0921-4488, 04/2015, Volume 125, pp. 26 - 33
The melanocortin-4 receptor (MC4R) is a G-protein coupled receptor superfamily member, which has been implicated in regulating food intake, energy balance and... 
MC4R | Sheep | SNP | Haplotype | Growth traits
Journal Article
Genetics in Medicine, ISSN 1098-3600, 09/2016, Volume 18, Issue 9, pp. 906 - 913
Purpose: Geisinger Health System (GHS) provides an ideal platform for Precision Medicine. Key elements are the integrated health system, stable patient... 
genetic association | genomics | electronic health records | biobank | COMMON VARIANTS | TCF7L2 | ASSOCIATION ANALYSIS | FTO GENE | RISK | MC4R | OBESITY | REPLICATION | GENETICS & HEREDITY | WEIGHT | CONFERS | Phenotype | Public Health | Biological Specimen Banks | Humans | Biomedical Research | Genotype | Electronic Health Records | Precision Medicine
Journal Article
Journal of Mazandaran University of Medical Sciences, ISSN 1735-9279, 08/2018, Volume 28, Issue 163, pp. 10 - 23
Journal Article
Journal Article