X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
science & technology (1503) 1503
apoptosis (1364) 1364
life sciences & biomedicine (1270) 1270
humans (1119) 1119
mcl-1 (1111) 1111
mcl-1 protein (844) 844
oncology (644) 644
proteins (576) 576
cell line, tumor (575) 575
cancer (538) 538
apoptosis - drug effects (523) 523
animals (466) 466
cell biology (466) 466
proto-oncogene proteins c-bcl-2 - metabolism (429) 429
myeloid cell leukemia sequence 1 protein (414) 414
bcl-2 protein (374) 374
mice (325) 325
myeloid cell leukemia sequence 1 protein - metabolism (316) 316
cell death (311) 311
leukemia (307) 307
biochemistry & molecular biology (300) 300
female (288) 288
antineoplastic agents - pharmacology (268) 268
kinases (266) 266
signal transduction (266) 266
gene expression (265) 265
proto-oncogene proteins c-bcl-2 - genetics (256) 256
cell survival (247) 247
tumors (235) 235
bcl-x protein (232) 232
science & technology - other topics (231) 231
hemic and lymphatic diseases (230) 230
mitochondria (229) 229
phosphorylation (228) 228
multidisciplinary sciences (226) 226
myeloid cell leukemia sequence 1 protein - genetics (226) 226
research article (210) 210
medicine (206) 206
cell cycle (205) 205
bcl-2 (203) 203
chemotherapy (193) 193
science (193) 193
cell proliferation (179) 179
male (177) 177
analysis (173) 173
caspase (169) 169
research (168) 168
cancer therapies (166) 166
health aspects (161) 161
bax protein (157) 157
cell proliferation - drug effects (153) 153
pharmacology & pharmacy (153) 153
cell survival - drug effects (152) 152
hematology (150) 150
apoptosis - genetics (142) 142
cytotoxicity (141) 141
biology (140) 140
flow cytometry (135) 135
proto-oncogene proteins c-bcl-2 - antagonists & inhibitors (134) 134
genetic aspects (130) 130
sulfonamides - pharmacology (130) 130
signal transduction - drug effects (129) 129
xenografts (128) 128
care and treatment (124) 124
neoplasms (122) 122
inhibition (118) 118
breast cancer (115) 115
caspase-3 (113) 113
xenograft model antitumor assays (113) 113
drug synergism (111) 111
akt protein (110) 110
mutation (110) 110
blotting, western (109) 109
medical prognosis (109) 109
apoptosis regulatory proteins - metabolism (107) 107
drug resistance (105) 105
inhibitors (105) 105
lymphomas (104) 104
gene expression regulation, neoplastic - drug effects (102) 102
apoptosis - physiology (101) 101
myeloid cell leukemia sequence 1 protein - antagonists & inhibitors (101) 101
cell growth (99) 99
lung cancer (99) 99
tumor cells, cultured (99) 99
middle aged (98) 98
transcription (98) 98
gene expression regulation, neoplastic (97) 97
mice, nude (97) 97
multiple myeloma (96) 96
mcl‐1 (95) 95
neoplasm proteins - metabolism (95) 95
signaling (95) 95
tumor cell lines (95) 95
bcl-xl (94) 94
rna interference (94) 94
down-regulation (93) 93
lymphocytes b (92) 92
anticancer properties (91) 91
immunology (91) 91
transfection (89) 89
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (1890) 1890
Chinese (95) 95
French (16) 16
Japanese (8) 8
Korean (3) 3
German (2) 2
Czech (1) 1
Danish (1) 1
Norwegian (1) 1
Portuguese (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Cell death and differentiation, ISSN 1476-5403, 11/2017, Volume 25, Issue 1, pp. 27 - 36
Impaired apoptosis plays a central role in cancer development and limits the efficacy of conventional cytotoxic therapies. Deepening understanding of how... 
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Drugs | Medical research | Arbiters | Therapy | Chronic lymphatic leukemia | Bcl-2 protein | Leukemia | Clinical trials | Cytotoxicity | Drug development | Survival | Mcl-1 protein | Mimicry | Proteins | Sketches | Cancer | Apoptosis | Index Medicus | Review
Journal Article
FEBS letters, ISSN 0014-5793, 07/2010, Volume 584, Issue 14, pp. 2981 - 2989
Apoptosis, an essential and basic biological phenomenon, is regulated in a complex manner by a multitude of factors. Myeloid cell leukemia 1 (Mcl-1), an... 
Post-translational modification | Phosphorylation | Myeloid cell leukemia 1 | Apoptosis | granzyme B | Bcl-2 homologous antagonist killer | MULE | JNK | HIF-1α | BFL-1/A1 | NF-κB | p53 upregulated modulator of apoptosis | CHX | GM-CSF | GrB | checkpoint 1 protein | cAMP response element binding protein | cyclin dependent kinase 1 | BCL-XL | Mir-29b | β-TrCP | Bcl-2 homology | proliferating cell nuclear antigen | extracellular regulated protein kinase | PEST | STAT response element | Bcl-2-associated protein X | CRE | micro inhibiting RNA 29b | BH3 interacting domain death agonist | proline/glutamic acid/serine/threonine | ERK | beta transducin-containing protein | Pin-1 | PCNA | MCL-1 | SRE | nuclear factor kappa B | C-Jun N-terminal kinase | peptidyl-prolyl cis-trans isomerase NIMA interacting protein 1 | BCL-2 | signal transducers and activators of transcription | CREB | BID | interleukin | B-cell lymphoma 2 | MCL-1 ubiquitin ligase | cAMP response element | hypoxia-inducible factor 1α | Bcl-2 like protein X | VEGF | BAK | Bcl-2 related protein A1 | cycloheximide | STAT | vascular endothelial growth factor | CHK-1 | granulocyte–macrophage colony-stimulating factor | BAX | PUMA | CDK-1 | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Myeloid Progenitor Cells - metabolism | Humans | Leukemia, Myeloid - genetics | Apoptosis - genetics | Leukemia - metabolism | Protein Structure, Tertiary - genetics | Lymphoma, B-Cell - genetics | Proteins - genetics | Proteins - metabolism | Myeloid Cells - metabolism | Protein Processing, Post-Translational | Dimerization | B-Lymphocytes - metabolism | Leukemia - genetics | Ubiquitin | Ligases | Cyclohexane | Proline | Lymphomas | Macrophage colony stimulating factor | Tumor proteins | Glutamate | Vascular endothelial growth factor | Protein binding | Index Medicus
Journal Article
Clinical cancer research, ISSN 1557-3265, 11/2017, Volume 23, Issue 21, pp. 6567 - 6579
Purpose: The mechanisms accounting for anticancer activity of AZD9291 (osimertinib or TAGRISSO), an approved third-generation EGFR inhibitor, in EGFR-mutant... 
Life Sciences & Biomedicine | Oncology | Science & Technology | Apoptosis - drug effects | Humans | ErbB Receptors - genetics | Myeloid Cell Leukemia Sequence 1 Protein - metabolism | Protein Kinase Inhibitors - adverse effects | Proteolysis - drug effects | Aniline Compounds - administration & dosage | Carcinoma, Non-Small-Cell Lung - pathology | ErbB Receptors - antagonists & inhibitors | Carcinoma, Non-Small-Cell Lung - genetics | Bcl-2-Like Protein 11 - genetics | Myeloid Cell Leukemia Sequence 1 Protein - genetics | Xenograft Model Antitumor Assays | Protein Kinase Inhibitors - administration & dosage | Drug Resistance, Neoplasm - genetics | Animals | Bcl-2-Like Protein 11 - metabolism | MAP Kinase Signaling System - drug effects | Acrylamides - administration & dosage | Mice | Carcinoma, Non-Small-Cell Lung - drug therapy | Mutation | Aniline Compounds - adverse effects | Acrylamides - adverse effects | Drug Resistance, Neoplasm - drug effects | Drugs | Flow cytometry | Biotechnology | Phosphorylation | Animal models | Lung cancer | Drug development | Western blotting | Anticancer properties | Degradation | Proteins | Modulation | Xenografts | Epidermal growth factor receptors | Extracellular signal-regulated kinase | Non-small cell lung carcinoma | siRNA | Gene expression | Mcl-1 protein | Cytometry | Sensitivity | Inhibitors | Experimental design | Cell number | Antitumor activity | In vivo methods and tests | Annexin V | BIM protein | Cancer | Apoptosis | Index Medicus | Mcl-1 | MEK | Bim | apoptosis | EGFR inhibitors | AZD9291 | acquired resistance
Journal Article
Journal Article
PloS one, ISSN 1932-6203, 12/2013, Volume 8, Issue 12
The incorrect version of the figure represents miR-26a expression analysis in 20 breast cancer specimens and 15 normal breast tissues. (2013) Correction:... 
Migration | Breast cancer | Mcl-1 protein
Journal Article