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dna replication (192) 192
index medicus (183) 183
cell biology (117) 117
biochemistry & molecular biology (107) 107
mcm2-7 helicase (105) 105
cell cycle proteins - metabolism (87) 87
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complex (51) 51
article (49) 49
deoxyribonucleic acid--dna (49) 49
saccharomyces cerevisiae proteins - metabolism (49) 49
minichromosome maintenance proteins - metabolism (48) 48
phosphorylation (48) 48
dna helicase (45) 45
genetics & heredity (45) 45
protein binding (45) 45
dna helicases - metabolism (42) 42
dormant origins (42) 42
initiation (42) 42
excess mcm2-7 (40) 40
dna-replication (39) 39
helicase (39) 39
cdc45 (37) 37
chromatin (36) 36
eukaryotic dna-replication (36) 36
cell cycle proteins - genetics (34) 34
chromatin - metabolism (34) 34
nuclear proteins - metabolism (34) 34
replication origin (34) 34
saccharomyces cerevisiae - genetics (34) 34
minichromosome maintenance proteins (33) 33
multidisciplinary sciences (33) 33
replication (33) 33
saccharomyces cerevisiae - metabolism (33) 33
cell-cycle (32) 32
research (32) 32
origin recognition complex (31) 31
biology (29) 29
dna biosynthesis (29) 29
cell cycle proteins - chemistry (28) 28
dna - metabolism (28) 28
analysis (27) 27
cancer (27) 27
mutation (27) 27
protein (27) 27
structural basis (27) 27
molecular biology (26) 26
dna replication - physiology (25) 25
mcm2-7 complex (25) 25
dna replication - genetics (24) 24
mice (24) 24
minichromosome maintenance proteins - genetics (24) 24
dna damage (23) 23
human-cells (23) 23
polymerase-alpha (23) 23
s phase (23) 23
yeast (23) 23
physiological aspects (22) 22
chromosomal proteins, non-histone - metabolism (21) 21
orc (21) 21
saccharomyces cerevisiae proteins - genetics (21) 21
amino acid sequence (20) 20
biochemistry (20) 20
dna-binding proteins - chemistry (20) 20
eukaryotes (20) 20
genetic aspects (20) 20
genetics (20) 20
gins (20) 20
models, molecular (20) 20
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binding (19) 19
developmental biology (19) 19
dna-binding proteins - genetics (19) 19
genomes (19) 19
minichromosome maintenance proteins - chemistry (19) 19
cmg helicase (18) 18
protein-serine-threonine kinases - metabolism (18) 18
replication initiation (18) 18
saccharomyces cerevisiae proteins - chemistry (18) 18
xenopus egg extracts (18) 18
activation (17) 17
biophysics (17) 17
cell division (17) 17
kinases (17) 17
molecular sequence data (17) 17
origin dna (17) 17
cyclin-dependent kinases (16) 16
mcm2–7 (16) 16
mechanism (16) 16
minichromosome maintenance complex component 7 (16) 16
atp-hydrolysis (15) 15
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1. Full Text Bidirectional eukaryotic DNA replication is established by quasi-symmetrical helicase loading
by Coster, Gideon and Diffley, John F. X
Science, ISSN 0036-8075, 07/2017, Volume 357, Issue 6348, pp. 314 - 318
Bidirectional replication from eukaryotic DNA replication origins requires the loading of two ring-shaped minichromosome maintenance (MCM) helicases around DNA... 
MCM2-7 HELICASE | CHROMOSOME | ORIGINS | COMPLEX | ACTIVATION | INITIATION | MULTIDISCIPLINARY SCIENCES | ARCHITECTURE | SITES | SACCHAROMYCES-CEREVISIAE | BINDING | DNA Helicases - metabolism | Replication Origin | Saccharomyces cerevisiae - genetics | Minichromosome Maintenance Proteins - metabolism | Saccharomyces cerevisiae Proteins - metabolism | DNA Replication | Origin Recognition Complex - metabolism | Binding Sites | DNA replication | Nucleotide sequencing | Observations | Methods | DNA sequencing | Translocation | Origins | Yeast | Nucleotide sequence | Archaea | Hexamers | Replication initiation | Origin recognition complex | Gene sequencing | DNA biosynthesis | DNA helicase | Eukaryotes | Replication origins | Replication | Binding sites | Recognition | Deoxyribonucleic acid--DNA
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2. Full Text A key role for Ctf4 in coupling the MCM2‐7 helicase to DNA polymerase α within the eukaryotic replisome
by Gambus, Agnieszka and van Deursen, Frederick and Polychronopoulos, Dimitrios and Foltman, Magdalena and Jones, Richard C and Edmondson, Ricky D and Calzada, Arturo and Labib, Karim
The EMBO Journal, ISSN 0261-4189, 10/2009, Volume 28, Issue 19, pp. 2992 - 3004
The eukaryotic replisome is a crucial determinant of genome stability, but its structure is still poorly understood. We found previously that many regulatory... 
DNA polymerase α | replisome progression complex | GINS | MCM2‐7 | Ctf4 | MCM2-7 | DNA polymerase a | Replisome progression complex | SISTER-CHROMATID COHESION | CATALYTIC SUBUNIT | FISSION YEAST | BUDDING YEAST | BIOCHEMISTRY & MOLECULAR BIOLOGY | TOPOISOMERASE-I | DNA polymerase alpha | SACCHAROMYCES-CEREVISIAE | S-PHASE CHECKPOINT | CHROMOSOMAL DNA | CELL BIOLOGY | GINS COMPLEX | REPLICATION FORK PROGRESSION | Saccharomyces cerevisiae - genetics | Cell Cycle Proteins - metabolism | Chromosomal Proteins, Non-Histone | DNA Replication | Nuclear Proteins - metabolism | Minichromosome Maintenance Complex Component 7 | DNA - metabolism | DNA-Binding Proteins - metabolism | Saccharomyces cerevisiae - cytology | Saccharomyces cerevisiae - metabolism | Cell Cycle | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | DNA Polymerase I - metabolism | Fungal Proteins - metabolism
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3. Full Text Conserved mechanism for coordinating replication fork helicase assembly with phosphorylation of the helicase
by Irina Bruck and Daniel L. Kaplan
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2015, Volume 112, Issue 36, pp. 11223 - 11228
Dbf4-dependent kinase (DDK) phosphorylates minichromosome maintenance 2 (Mcm2) during S phase in yeast, and Sld3 recruits cell division cycle 45 (Cdc45) to... 
DNA replication | BUDDING YEAST | MULTIDISCIPLINARY SCIENCES | EUKARYOTIC DNA-REPLICATION | CYCLIN-DEPENDENT KINASE | SINGLE-STRANDED-DNA | SLD3 | kinase | initiation | CDC45 | S-PHASE | MCM2-7 COMPLEX | helicase | PROTEINS | phosphorylation | Phosphorylation | Saccharomyces cerevisiae - genetics | Humans | Minichromosome Maintenance Proteins - metabolism | Cell Cycle Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | DNA Replication | Nuclear Proteins - metabolism | Minichromosome Maintenance Complex Component 2 - genetics | Signal Transduction - genetics | Minichromosome Maintenance Complex Component 2 - metabolism | Saccharomyces cerevisiae Proteins - genetics | DNA-Binding Proteins - genetics | Blotting, Western | DNA-Binding Proteins - metabolism | Saccharomyces cerevisiae - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Cell Cycle Proteins - genetics | Protein Binding | Minichromosome Maintenance Proteins - genetics | Mutation | Nuclear Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Saccharomyces cerevisiae - growth & development | Physiological aspects | Observations | Helicases | Phosphotransferases | Biological Sciences
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4. Full Text Structural basis of Mcm2-7 replicative helicase loading by ORC-Cdc6 and Cdt1
by Yuan, Zuanning and Riera, Alberto and Bai, Lin and Sun, Jingchuan and Nandi, Saikat and Spanos, Christos and Chen, Zhuo Angel and Barbon, Marta and Rappsilber, Juri and Stillman, Bruce and Speck, Christian and Li, Huilin
Nature Structural and Molecular Biology, ISSN 1545-9993, 03/2017, Volume 24, Issue 3, pp. 316 - 324
To initiate DNA replication, the origin recognition complex (ORC) and Cdc6 load an Mcm2-7 double hexamer onto DNA. Without ATP hydrolysis, ORC-Cdc6 recruits... 
ORC | ATPASE ACTIVITY | PROTEIN | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | ORC/CDC6/MCM2-7 COMPLEX | DNA-REPLICATION | ORIGIN RECOGNITION | CELL BIOLOGY | BIOPHYSICS | QUATERNARY STRUCTURE | BINDING | Minichromosome Maintenance Proteins - metabolism | Protein Multimerization | Cell Cycle Proteins - ultrastructure | DNA, Fungal - chemistry | Minichromosome Maintenance Proteins - chemistry | Cell Cycle Proteins - chemistry | DNA-Binding Proteins - metabolism | Minichromosome Maintenance Proteins - ultrastructure | Saccharomyces cerevisiae - metabolism | Mass Spectrometry | Protein Domains | Binding Sites | Saccharomyces cerevisiae Proteins - ultrastructure | Protein Structure, Secondary | Cell Cycle Proteins - metabolism | Models, Molecular | DNA Replication | Nucleotides - metabolism | DNA-Binding Proteins - chemistry | Cryoelectron Microscopy | DNA-Binding Proteins - ultrastructure | Replication Origin | DNA, Fungal - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Saccharomyces cerevisiae Proteins - chemistry | DNA replication | Molecular structure | Genetic research | Research | Properties | Helicases | Testing | Molecular biology | Deoxyribonucleic acid--DNA | Topology
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5. Full Text CMG helicase and DNA polymerase ε form a functional 15-subunit holoenzyme for eukaryotic leading-strand DNA replication
by Lance D. Langston and Dan Zhang and Olga Yurieva and Roxana E. Georgescu and Jeff Finkelstein and Nina Y. Yao and Chiara Indiani and Mike E. O'Donnell
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2014, Volume 111, Issue 43, pp. 15390 - 15395
DNA replication in eukaryotes is asymmetric, with separate DNA polymerases (Pol) dedicated to bulk synthesis of the leading and lagging strands. Pol α/primase... 
Circles | Yeasts | DNA replication | Gels | DNA | Mass spectroscopy | Lesions | Gin | Saccharomyces cerevisiae | Protein subunits | Polymerase | Helicase | Replication fork | CMG | MCM2-7 HELICASE | COMPLEX | BUDDING YEAST | REPLISOME | polymerase | GINS | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | SACCHAROMYCES-CEREVISIAE | CHROMOSOMAL DNA | IN-VITRO | replication fork | helicase | NONCATALYTIC SUBUNIT | Substrate Specificity | DNA Replication | DNA Helicases - isolation & purification | DNA Polymerase II - metabolism | DNA, Circular - metabolism | Protein Subunits - metabolism | DNA Helicases - metabolism | Holoenzymes - metabolism | Time Factors | Models, Biological | Saccharomyces cerevisiae Proteins - metabolism | Saccharomyces cerevisiae - enzymology | Chromatography, Gel | Biological Sciences
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6. Full Text A Ctf4 trimer couples the CMG helicase to DNA polymerase alpha in the eukaryotic replisome
by Simon, AC and Zhou, JC and Perera, RL and van Deursen, F and Evrin, C and Ivanova, ME and Kilkenny, ML and Renault, L and Kjaer, S and Matak-Vinkovic, D and Labib, K and Costa, A and Pellegrini, L
NATURE, ISSN 0028-0836, 06/2014, Volume 510, Issue 7504, pp. 293 - 293
Efficient duplication of the genome requires the concerted action of helicase and DNA polymerases at replication forks(1) to avoid stalling of the replication... 
SISTER-CHROMATID COHESION | MCM2-7 HELICASE | COMPLEX | ACTIVATION | REPLICATION | PROTEIN | METABOLISM | GINS | MULTIDISCIPLINARY SCIENCES | STOICHIOMETRY | PROGRESSION | Minichromosome Maintenance Proteins - metabolism | Protein Multimerization | Molecular Sequence Data | Multienzyme Complexes - metabolism | Crystallography, X-Ray | Saccharomyces cerevisiae - ultrastructure | DNA Helicases - ultrastructure | DNA-Directed DNA Polymerase - chemistry | Minichromosome Maintenance Proteins - chemistry | Protein Subunits - metabolism | DNA-Binding Proteins - metabolism | Protein Structure, Quaternary | Conserved Sequence | Saccharomyces cerevisiae Proteins - ultrastructure | Amino Acid Sequence | DNA Helicases - chemistry | Catalytic Domain | Models, Molecular | DNA Replication | Nuclear Proteins - metabolism | DNA Polymerase I - chemistry | Microscopy, Electron | Nuclear Proteins - chemistry | DNA-Binding Proteins - chemistry | Saccharomyces cerevisiae - chemistry | Amino Acid Motifs | Multienzyme Complexes - chemistry | DNA-Binding Proteins - ultrastructure | DNA Helicases - metabolism | DNA Polymerase I - ultrastructure | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Protein Subunits - chemistry | DNA-Directed DNA Polymerase - metabolism | DNA Polymerase I - metabolism | Saccharomyces cerevisiae Proteins - chemistry
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7. Full Text A unique DNA entry gate serves for regulated loading of the eukaryotic replicative helicase MCM2-7 onto DNA
by Samel, Stefan A and Fernández-Cid, Alejandra and Sun, Jingchuan and Riera, Alberto and Tognetti, Silvia and Carmen Herrera, M and Li, Huilin and Speck, Christian
Genes and Development, ISSN 0890-9369, 2014, Volume 28, Issue 15, pp. 1653 - 1666
The regulated loading of the replicative helicase minichromosome maintenance proteins 2-7 (MCM2-7) onto replication origins is a prerequisite for replication... 
pre-RC | Genomic stability | DNA replication | DNA licensing | Replicative helicase | Cancer | CELL NUCLEAR ANTIGEN | genomic stability | BUDDING YEAST | FACTOR-C | ACTIVE-SITES | DEVELOPMENTAL BIOLOGY | SACCHAROMYCES-CEREVISIAE | ORC/CDC6/MCM2-7 COMPLEX | ORIGIN DNA | CELL BIOLOGY | HEXAMERIC HELICASE | replicative helicase | GENETICS & HEREDITY | cancer | BINDING | ATP-HYDROLYSIS | Saccharomyces cerevisiae - genetics | Minichromosome Maintenance Proteins - metabolism | Multiprotein Complexes - genetics | Minichromosome Maintenance Proteins - chemistry | Protein Subunits - metabolism | Hydrolysis | Minichromosome Maintenance Proteins - ultrastructure | Multiprotein Complexes - ultrastructure | Multiprotein Complexes - chemistry | Cell Cycle | Chromosomes, Fungal - metabolism | Adenosine Triphosphate - metabolism | Replication Origin - physiology | DNA, Fungal - metabolism | Saccharomyces cerevisiae - enzymology | Minichromosome Maintenance Proteins - genetics | Protein Subunits - chemistry | Enzyme Activation | Protein Subunits - genetics | Stability | Health aspects | DNA | Analysis | Genomics | Research Paper
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8. Full Text Cryo-EM structure of a helicase loading intermediate containing ORC-Cdc6-Cdt1-MCM2-7 bound to DNA
by Sun, Jingchuan and Evrin, Cecile and Samel, Stefan A and Fernández-Cid, Alejandra and Riera, Alberto and Kawakami, Hironori and Stillman, Bruce and Speck, Christian and Li, Huilin and Brookhaven National Lab. (BNL), Upton, NY (United States)
Nature Structural and Molecular Biology, ISSN 1545-9993, 08/2013, Volume 20, Issue 8, pp. 944 - 951
In eukaryotes, the Cdt1-bound replicative helicase core MCM2-7 is loaded onto DNA by the ORC-Cdc6 ATPase to form a prereplicative complex (pre-RC) with an... 
MCM2-7 HELICASE | ATPASE ACTIVITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | CMG COMPLEX | ELECTRON-MICROSCOPY | EUKARYOTIC CELLS | SACCHAROMYCES-CEREVISIAE | PROTEIN COMPLEX | CELL BIOLOGY | IN-VITRO | CONFORMATIONAL-CHANGES | BIOPHYSICS | REPLICATION ORIGIN RECOGNITION | Immunoprecipitation | Mutagenesis, Site-Directed | Chromosomal Proteins, Non-Histone - metabolism | Cell Cycle Proteins - metabolism | Models, Molecular | Origin Recognition Complex - chemistry | DNA, Fungal - chemistry | Origin Recognition Complex - metabolism | DNA-Binding Proteins - chemistry | Saccharomyces cerevisiae - chemistry | Cell Cycle Proteins - chemistry | Cryoelectron Microscopy | DNA-Binding Proteins - metabolism | Multiprotein Complexes - chemistry | DNA Replication - physiology | Image Processing, Computer-Assisted | Cloning, Molecular | DNA, Fungal - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Protein Conformation | Chromosomal Proteins, Non-Histone - chemistry | Saccharomyces cerevisiae Proteins - chemistry | Crystals | Physiological aspects | Research | Nucleotide sequencing | Structure | Helicases | DNA-ligand interactions | DNA sequencing | Enzymes | Molecular biology | Deoxyribonucleic acid--DNA | Crystal structure | BASIC BIOLOGICAL SCIENCES
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9. Full Text Selective Bypass of a Lagging Strand Roadblock by the Eukaryotic Replicative DNA Helicase
by Fu, Yu V and Yardimci, Hasan and Long, David T and Guainazzi, Angelo and Bermudez, Vladimir P and Hurwitz, Jerard and van Oijen, Antoine and Schärer, Orlando D and Walter, Johannes C
Cell, ISSN 0092-8674, 2011, Volume 146, Issue 6, pp. 931 - 941
The eukaryotic replicative DNA helicase, CMG, unwinds DNA by an unknown mechanism. In some models, CMG encircles and translocates along one strand of DNA while... 
MCM2-7 HELICASE | HEXAMERIC HELICASE | MINICHROMOSOME MAINTENANCE PROTEIN | COMPLEX | ORIGIN | CDC45 | MECHANISM | STRUCTURAL BASIS | INITIATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | INTERSTRAND CROSS-LINK | CELL BIOLOGY | DNA Helicases - metabolism | Animals | Xenopus - metabolism | Models, Biological | DNA, Single-Stranded - metabolism | S Phase | DNA Replication | DNA - metabolism | Amphibians | DNA | Analysis
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10. Full Text Cdc45 (cell division cycle protein 45) guards the gate of the Eukaryote Replisome helicase stabilizing leading strand engagement
by Tatjana Petojevic and James J. Pesavento and Alessandro Costa and Jingdan Liang and Zhijun Wang and James M. Berger and Michael R. Botchan
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2015, Volume 112, Issue 3, pp. E249 - E258
DNA replication licensing is now understood to be the pathway that leads to the assembly of double hexamers of minichromosome maintenance (Mcm2–7) at origin... 
CMG helicase | DNA replication | RecJ fold | Cdc45 | Mcm2/5 gate | MCM2-7 HELICASE | FORK | MECHANISM | MULTIDISCIPLINARY SCIENCES | FUNCTIONAL INSIGHTS | DNA-REPLICATION | GINS COMPLEX | REQUIRES | BINDING | REPLICATIVE HEXAMERIC HELICASE | REVEALS | Cell Cycle Proteins - chemistry | Sequence Homology, Amino Acid | Amino Acid Sequence | DNA Helicases - metabolism | Molecular Sequence Data | DNA - metabolism | Cell Cycle Proteins - physiology | Fluorescent Dyes | Physiological aspects | Cell division | DNA binding proteins | Observations | Helicases | Biological Sciences | 5 gate | PNAS Plus | Mcm2
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11. Full Text Activation of the replicative DNA helicase: breaking up is hard to do
by Boos, Dominik and Frigola, Jordi and Diffley, John FX
Current Opinion in Cell Biology, ISSN 0955-0674, 2012, Volume 24, Issue 3, pp. 423 - 430
The precise duplication of the eukaryotic genome is accomplished by carefully coordinating the loading and activation of the replicative DNA helicase so that... 
Internal Medicine | MCM2-7 HELICASE | MINICHROMOSOME MAINTENANCE PROTEIN | IN-VITRO | BUDDING YEAST | STRUCTURAL BASIS | S-PHASE | EUKARYOTIC CELLS | SINGLE-STRANDED-DNA | CDK-DEPENDENT PHOSPHORYLATION | SACCHAROMYCES-CEREVISIAE | CELL BIOLOGY | Cell Cycle - genetics | DNA Helicases - chemistry | Humans | Cell Cycle Proteins - metabolism | DNA Replication | Nuclear Proteins - metabolism | Minichromosome Maintenance Complex Component 2 | DNA Helicases - metabolism | Replication Origin | Cell Cycle Proteins - genetics | Enzyme Activation | Nuclear Proteins - genetics | DNA Helicases - physiology | Proteins | DNA | DNA helicase | Replication origins | Reviews | Cdc45 protein | Cell cycle | MCM2-7 protein | Genomes | G1 phase
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12. Full Text Single-Molecule Studies of Origin Licensing Reveal Mechanisms Ensuring Bidirectional Helicase Loading
by Ticau, Simina and Friedman, Larry J and Ivica, Nikola A and Gelles, Jeff and Bell, Stephen P
Cell, ISSN 0092-8674, 04/2015, Volume 161, Issue 3, pp. 513 - 525
Loading of the ring-shaped Mcm2–7 replicative helicase around DNA licenses eukaryotic origins of replication. During loading, Cdc6, Cdt1, and the... 
MCM2-7 HELICASE | COMPLEX | ACTIVATION | INITIATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | MICROSCOPY | ATP-HYDROLYSIS | DNA-REPLICATION | CELL BIOLOGY | Saccharomyces cerevisiae - cytology | Saccharomyces cerevisiae - metabolism | Cell Cycle Proteins - isolation & purification | Minichromosome Maintenance Proteins - isolation & purification | Minichromosome Maintenance Proteins - metabolism | Cell Cycle Proteins - metabolism | Fluorescence Resonance Energy Transfer | Saccharomyces cerevisiae - enzymology | DNA Replication | Origin Recognition Complex - metabolism | Proteins | Fluorescence | DNA-ligand interactions
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13. Full Text The mechanism of DNA unwinding by the eukaryotic replicative helicase
by Burnham, DR and Kose, HB and Hoyle, RB and Yardimci, H
NATURE COMMUNICATIONS, ISSN 2041-1723, 05/2019, Volume 10, Issue 1, pp. 2159 - 14
Accurate DNA replication is tightly regulated in eukaryotes to ensure genome stability during cell division and is performed by the multi-protein replisome. At... 
MCM2-7 HELICASE | FORCE | SINGLE-MOLECULE | HIGH-THROUGHPUT | CMG HELICASE | MULTIDISCIPLINARY SCIENCES | DYNAMICS | TIME | STERIC EXCLUSION | STRAND | REVEALS | DNA biosynthesis | DNA helicase | Eukaryotes | Drosophila | Random walk | Cdc45 protein | Cell division | Unwinding | Replication | Genomes | Deoxyribonucleic acid--DNA | Recombinant
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14. Full Text Cryo-EM structures of the eukaryotic replicative helicase bound to a translocation substrate
by Abid Ali, Ferdos and Renault, Ludovic and Gannon, Julian and Gahlon, Hailey L and Kotecha, Abhay and Zhou, Jin Chuan and Rueda, David and Costa, Alessandro
Nature Communications, ISSN 2041-1723, 02/2016, Volume 7, Issue 1, p. 10708
The Cdc45-MCM-GINS (CMG) helicase unwinds DNA during the elongation step of eukaryotic genome duplication and this process depends on the MCM ATPase function.... 
HEXAMERIC HELICASE | MCM2-7 HELICASE | COMPLEX | ARCHAEAL MCM | MECHANISM | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | ELECTRON-MICROSCOPY | FUNCTIONAL INSIGHTS | PROTEINS | DNA-REPLICATION | Cryoelectron Microscopy | DNA - genetics | DNA Helicases - metabolism | Eukaryota - genetics | DNA Replication | DNA - ultrastructure | DNA - metabolism | DNA Helicases - ultrastructure | Eukaryota - ultrastructure | Eukaryota - enzymology
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