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1. Full Text A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase α within the eukaryotic replisome
by Edmondson, Ricky D and van Deursen, Frederick and Jones, Richard C and Calzada, Arturo and Labib, Karim and Polychronopoulos, Dimitrios and Gambus, Agnieszka and Foltman, Magdalena
The EMBO journal, ISSN 0261-4189, 10/2009, Volume 28, Issue 19, pp. 2992 - 3004
DNA polymerase α | replisome progression complex | GINS | MCM2‐7 | Ctf4 | MCM2-7 | DNA polymerase a | Replisome progression complex | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Saccharomyces cerevisiae - genetics | Cell Cycle Proteins - metabolism | Chromosomal Proteins, Non-Histone | DNA Replication | Nuclear Proteins - metabolism | Minichromosome Maintenance Complex Component 7 | DNA - metabolism | DNA-Binding Proteins - metabolism | Saccharomyces cerevisiae - cytology | Saccharomyces cerevisiae - metabolism | Cell Cycle | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | DNA Polymerase I - metabolism | Fungal Proteins - metabolism | Index Medicus
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2. Full Text Activation of the replicative DNA helicase: breaking up is hard to do
by Boos, Dominik and Frigola, Jordi and Diffley, John FX
Current opinion in cell biology, ISSN 0955-0674, 2012, Volume 24, Issue 3, pp. 423 - 430
Internal Medicine | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cell Cycle - genetics | DNA Helicases - chemistry | Humans | Cell Cycle Proteins - metabolism | DNA Replication | Nuclear Proteins - metabolism | Minichromosome Maintenance Complex Component 2 | DNA Helicases - metabolism | Replication Origin | Cell Cycle Proteins - genetics | Enzyme Activation | Nuclear Proteins - genetics | DNA Helicases - physiology | Proteins | DNA | Index Medicus | DNA helicase | Replication origins | Reviews | Cdc45 protein | Cell cycle | MCM2-7 protein | Genomes | G1 phase
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3. Full Text Dynamic loading and redistribution of the Mcm2‐7 helicase complex through the cell cycle
by Powell, Sara K and MacAlpine, Heather K and Prinz, Joseph A and Li, Yulong and Belsky, Jason A and MacAlpine, David M
The EMBO journal, ISSN 0261-4189, 02/2015, Volume 34, Issue 4, pp. 531 - 543
DNA replication | chromatin | Mcm2‐7 | cell cycle | Chromatin | Cell cycle | Mcm2-7 | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cell Cycle - genetics | Animals | RNA Interference | Drosophila | Minichromosome Maintenance Proteins - metabolism | Cells, Cultured | Fluorescent Antibody Technique | Cell Cycle - physiology | Minichromosome Maintenance Proteins - genetics | Drosophila Proteins - genetics | Drosophila Proteins - metabolism | Blotting, Western | Genomes | Mutation | Insects | Cyclin-dependent kinases | Index Medicus
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4. Full Text Mcm10 regulates DNA replication elongation by stimulating the CMG replicative helicase
by Lõoke, Marko and Maloney, Michael F and Bell, Stephen P
Genes & development, ISSN 0890-9369, 02/2017, Volume 31, Issue 3, pp. 291 - 305
Cdc45/Mcm2-7/GINS | DNA replication fork | Cell cycle | Reconstituted DNA replication | S. cerevisiae | Genetics & Heredity | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | Amino Acid Sequence | DNA Helicases - chemistry | Saccharomyces cerevisiae - genetics | Minichromosome Maintenance Proteins - metabolism | DNA Replication | Nuclear Proteins - metabolism | Saccharomyces cerevisiae Proteins - genetics | DNA-Binding Proteins - genetics | Transcription Elongation, Genetic | DNA-Binding Proteins - metabolism | Saccharomyces cerevisiae - metabolism | Sequence Homology, Amino Acid | DNA Helicases - metabolism | Replication Origin | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Minichromosome Maintenance Proteins - genetics | Nuclear Proteins - genetics | Saccharomyces cerevisiae - growth & development | DNA replication | Research | Oligosaccharides | Helicases | DNA-ligand interactions | Index Medicus | Mcm2–7 | cell cycle | GINS | Research Paper | reconstituted DNA replication | Cdc45
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5. Full Text DNA binding polarity, dimerization, and ATPase ring remodeling in the CMG helicase of the eukaryotic replisome
by Costa, Alessandro and Renault, Ludovic and Swuec, Paolo and Petojevic, Tatjana and Pesavento, James J and Ilves, Ivar and MacLellan-Gibson, Kirsty and Fleck, Roland A and Botchan, Michael R and Berger, James M
eLife, ISSN 2050-084X, 08/2014, Volume 3, Issue 2014, pp. 1 - 17
replication fork | DNA replication | helicase | motor proteins | AAA+ ATPase | Mcm2-7 | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Minichromosome Maintenance Proteins - metabolism | Protein Multimerization | Eukaryotic Cells - metabolism | Drosophila Proteins - metabolism | Minichromosome Maintenance Proteins - chemistry | Protein Subunits - metabolism | Cell Cycle Proteins - chemistry | DNA-Binding Proteins - metabolism | Drosophila melanogaster - metabolism | Multiprotein Complexes - metabolism | Adenosine Triphosphate - metabolism | Protein Structure, Quaternary | Repressor Proteins - metabolism | Protein Structure, Tertiary | Repressor Proteins - chemistry | Chromosomal Proteins, Non-Histone - metabolism | DNA, Single-Stranded - metabolism | RNA-Binding Proteins - chemistry | Cell Cycle Proteins - metabolism | RNA Splicing Factors | Adenosine Triphosphatases - metabolism | Models, Molecular | DNA Replication | DNA - metabolism | Drosophila Proteins - chemistry | Microscopy, Electron | DNA-Binding Proteins - chemistry | Adenosine Triphosphate - analogs & derivatives | DNA, Single-Stranded - chemistry | Multiprotein Complexes - ultrastructure | DNA - chemistry | Multiprotein Complexes - chemistry | Animals | Protein Binding | Adenosine Triphosphatases - chemistry | Protein Subunits - chemistry | Adenosine Triphosphate - chemistry | Chromosomal Proteins, Non-Histone - chemistry | RNA-Binding Proteins - metabolism | Medical research | Single-stranded DNA | Hexamers | Electron microscopy | DNA biosynthesis | DNA helicase | Handedness | Microscopy | Insects | Cdc45 protein | Cell cycle | Polarity | Dimerization | Deoxyribonucleic acid--DNA | Adenosine triphosphatase | Index Medicus
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6. Full Text Cell-Cycle-Regulated Interaction between Mcm10 and Double Hexameric Mcm2-7 Is Required for Helicase Splitting and Activation during S Phase
by Quan, Yun and Xia, Yisui and Liu, Lu and Cui, Jiamin and Li, Zhen and Cao, Qinhong and Chen, Xiaojiang S and Campbell, Judith L and Lou, Huiqiang
Cell reports (Cambridge), ISSN 2211-1247, 12/2015, Volume 13, Issue 11, pp. 2576 - 2586
DNA replication | cell cycle | Mcm10 | helicase activation | Mcm2-7 | Helicase activation | Cell cycle | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Saccharomyces cerevisiae - metabolism | Chromatin - metabolism | Cell Cycle Checkpoints | G1 Phase | DNA, Single-Stranded - metabolism | Minichromosome Maintenance Proteins - metabolism | S Phase | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Minichromosome Maintenance Proteins - genetics | Saccharomyces cerevisiae Proteins - genetics | Index Medicus
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7. Full Text Incorporation into the prereplicative complex activates the Mcm2-7 helicase for Cdc7-Dbf4 phosphorylation
by Francis, Laura I and Randell, John C. W and Takara, Thomas J and Uchima, Lilen and Bell, Stephen P
Genes & development, ISSN 0890-9369, 03/2009, Volume 23, Issue 5, pp. 643 - 654
DNA replication | Kinase targeting | Prereplication complex | Cdc7 | Dbf4 | Mcm2-7 | Genetics & Heredity | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | Phosphorylation | Saccharomyces cerevisiae - genetics | Cell Cycle Proteins - metabolism | Chromosomal Proteins, Non-Histone | Nuclear Proteins - metabolism | Minichromosome Maintenance Complex Component 7 | DNA-Binding Proteins - metabolism | Saccharomyces cerevisiae - metabolism | DNA Replication - physiology | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Protein-Serine-Threonine Kinases - metabolism | Fungal Proteins - metabolism | Index Medicus | Mcm2–7 | kinase targeting | Research Paper | prereplication complex
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8. Full Text Helicase loading: How to build a MCM2-7 double-hexamer
by Riera, Alberto and Tognetti, Silvia and Speck, Christian
Seminars in cell & developmental biology, ISSN 1084-9521, 06/2014, Volume 30, pp. 104 - 109
Helicase | DNA replication | Pre-RC | MCM2-7 | Licensing | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | Genomic Instability | Animals | Replication Origin | Humans | Minichromosome Maintenance Proteins - metabolism | Protein Multimerization | Protein Structure, Quaternary | Models, Molecular | DNA Replication | Minichromosome Maintenance Proteins - chemistry | Index Medicus
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9. Full Text MCM-BP regulates unloading of the MCM2-7 helicase in late S phase
by Nishiyama, Atsuya and Frappier, Lori and Méchali, Marcel
Genes & development, ISSN 0890-9369, 01/2011, Volume 25, Issue 2, pp. 165 - 175
Xenopus | Chromatin | DNA replication | MCM2-7 | MCM-BP | Cell cycle | Genetics & Heredity | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | Chromatin - metabolism | Chromosomal Proteins, Non-Histone - metabolism | Humans | Cell Cycle Proteins - metabolism | Gene Silencing | Minichromosome Maintenance Complex Component 2 | Protein Transport | DNA Helicases - metabolism | Animals | Carrier Proteins - metabolism | Cell Nucleus - metabolism | Protein Binding | S Phase - physiology | Xenopus Proteins - metabolism | HeLa Cells | RNA, Small Interfering - metabolism | Index Medicus | Life Sciences | Genetics | MCM2–7 | cell cycle | Research Paper | chromatin
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