X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
mct8 (71) 71
index medicus (65) 65
humans (50) 50
endocrinology & metabolism (49) 49
animals (40) 40
herndon-dudley-syndrome (37) 37
male (35) 35
monocarboxylic acid transporters - genetics (35) 35
monocarboxylate transporter-8 (32) 32
mutation (27) 27
mutations (27) 27
thyroid hormones - metabolism (27) 27
mice (26) 26
metabolism (23) 23
thyroid hormone (23) 23
allan-herndon-dudley syndrome (22) 22
hormones (22) 22
psychomotor retardation (22) 22
monocarboxylic acid transporters - metabolism (21) 21
thyroid-hormone transporter (20) 20
mental retardation, x-linked - genetics (19) 19
thyroid hormones (19) 19
brain (18) 18
mct8 deficiency (18) 18
mct8 gene (18) 18
membrane transport proteins - genetics (18) 18
muscle hypotonia - genetics (18) 18
gene (17) 17
mice, knockout (16) 16
monocarboxylate transporter 8 (16) 16
muscular atrophy - genetics (16) 16
thyroxine (16) 16
blood-brain-barrier (15) 15
female (15) 15
phenotype (15) 15
thyroid (15) 15
triiodothyronine - blood (14) 14
expression (13) 13
membrane transport proteins - metabolism (13) 13
physiological aspects (13) 13
thyroid gland (13) 13
article (12) 12
cell biology (12) 12
child (12) 12
child, preschool (12) 12
thyroxine - blood (12) 12
brain - metabolism (11) 11
deficiency (11) 11
deiodinase (11) 11
hypothyroidism (11) 11
linked psychomotor retardation (11) 11
triiodothyronine - metabolism (11) 11
identification (10) 10
organic anion transporter (10) 10
pediatrics (10) 10
abridged index medicus (9) 9
blood-brain (9) 9
iodide peroxidase - metabolism (9) 9
mental retardation, x-linked - diagnosis (9) 9
muscle hypotonia - diagnosis (9) 9
muscular atrophy - diagnosis (9) 9
thyroid hormone transporter (9) 9
allan–herndon–dudley syndrome (8) 8
genetics & heredity (8) 8
infant (8) 8
mental retardation (8) 8
mice deficient (8) 8
models, biological (8) 8
neurosciences (8) 8
pedigree (8) 8
proteins (8) 8
receptor (8) 8
thyroid gland - metabolism (8) 8
thyroxine - metabolism (8) 8
brain-development (7) 7
clinical neurology (7) 7
clinical phenotype (7) 7
congenital hypothyroidism (7) 7
gene expression (7) 7
intellectual disability - genetics (7) 7
monocarboxylic acid transporters - deficiency (7) 7
protein binding (7) 7
triiodothyronine (7) 7
biochemistry & molecular biology (6) 6
biological transport - genetics (6) 6
cell membrane - metabolism (6) 6
deiodinases (6) 6
endocrine system (6) 6
endocrinology (6) 6
functional-characterization (6) 6
genetic aspects (6) 6
magnetic resonance imaging (6) 6
monocarboxylic acid transporters - physiology (6) 6
neurons (6) 6
oatp1c1 (6) 6
organic anion transporters - metabolism (6) 6
paroxysmal dyskinesia (6) 6
thyrotropin (6) 6
triiodothyroacetic acid (6) 6
type-2 iodothyronine deiodinase (6) 6
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Endocrinology, ISSN 0022-0795, 2017, Volume 232, Issue 2, pp. 259 - 272
Journal Article
Metabolic Brain Disease, ISSN 0885-7490, 12/2019, Volume 34, Issue 6, pp. 1565 - 1575
Mutations in the thyroid hormone transporter MCT8 cause severe intellectual and motor disability and abnormal serum thyroid function tests, a syndrome known as... 
Biochemistry, general | Neurology | Neurosciences | Cerebral calcifications | Biomedicine | Metabolic Diseases | MCT8 deficiency | Thyroid hormone transporter | Oncology | Thyroid hormone | Leukoencephalopathy | MCT8 | Phenotypes | Basal ganglia | Trafficking | Thyroid gland | Hypothyroidism | Ganglia | Proteins | Genotype & phenotype | Genetic analysis | Fibroblasts | Mutation | Transporter | Thyroid
Journal Article
Endocrinology, ISSN 0013-7227, 10/2010, Volume 151, Issue 10, pp. 5053 - 5062
Journal Article
European Journal of Endocrinology, ISSN 0804-4643, 10/2011, Volume 165, Issue 4, pp. 555 - 561
Journal Article
Journal of Clinical Endocrinology and Metabolism, ISSN 0021-972X, 05/2008, Volume 93, Issue 5, pp. 1854 - 1859
Context: In monocarboxylate transporter 8 (MCT8) gene deficiency, a syndrome combining thyroid and neurological abnormalities, the central nervous system has... 
HERNDON-DUDLEY-SYNDROME | BRAIN-TUMOR | ABNORMALITIES | CONGENITAL HYPOTHYROIDISM | INFANTS | MCT8 GENE | PHENOTYPE | MUTATIONS | UMCG Approved | THYROID-HORMONE TRANSPORTER | LINKED PSYCHOMOTOR RETARDATION | ENDOCRINOLOGY & METABOLISM
Journal Article
PLoS Genetics, ISSN 1553-7390, 09/2014, Volume 10, Issue 9, p. e1004615
The mechanisms and treatment of psychomotor retardation, which includes motor and cognitive impairment, are indefinite. The Allan-Herndon-Dudley syndrome... 
MYELIN BASIC-PROTEIN | GENETICS & HEREDITY | GENE-EXPRESSION | MCT8 GENE | SPINAL-CORD | HYPOCRETIN NEURONS | CENTRAL-NERVOUS-SYSTEM | OLIGODENDROCYTE DEVELOPMENT | MONOCARBOXYLATE TRANSPORTER-8 | BLOOD-BRAIN-BARRIER | THYROID-HORMONE TRANSPORTER | Neurogranin - genetics | Thyroid Hormones - pharmacology | Mental Retardation, X-Linked - drug therapy | Muscle Hypotonia - diagnosis | Muscle Hypotonia - etiology | Myelin Sheath - metabolism | Thyroid Hormone Receptors alpha - genetics | Mental Retardation, X-Linked - diagnosis | Muscular Atrophy - diagnosis | Hypothalamo-Hypophyseal System | Neurons - metabolism | Gene Order | Muscular Atrophy - etiology | Disease Models, Animal | Gene Targeting | Zinc Fingers | Animals, Genetically Modified | Mental Retardation, X-Linked - etiology | Zebrafish | Photoperiod | Gene Knockout Techniques | Muscular Atrophy - drug therapy | Thyroid Gland | Gene Expression Regulation - drug effects | Motor Activity - genetics | Phenotype | Animals | Muscle Hypotonia - drug therapy | Pseudopodia - metabolism | Pseudopodia - genetics | Monocarboxylic Acid Transporters - genetics | Mutation | Kruppel-Like Transcription Factors - genetics | Embryonic development | Neural circuitry | Neurogenesis | Analysis | Neurons | Rodents | Nervous system | Behavior | Paralysis | Grants | Velocity | Experiments | Embryos
Journal Article
EBioMedicine, ISSN 2352-3964, 11/2017, Volume 25, Issue C, pp. 122 - 135
Journal Article
Journal Article
Clinical Nuclear Medicine, ISSN 0363-9762, 06/2013, Volume 38, Issue 6, pp. e276 - e278
ABSTRACTTwo siblings with psychomotor retardation, congenital hypotonia, spasticity, and no speech acquisition underwent MRI and Tc ethyl cysteinate dimer... 
Thyroid hormone | Cerebral blood flow | Monocarboxylate transporter 8 deficiency | MCT8 | SPECT
Journal Article
CLINICAL NUCLEAR MEDICINE, ISSN 0363-9762, 06/2013, Volume 38, Issue 6, pp. E276 - E278
Two siblings with psychomotor retardation, congenital hypotonia, spasticity, and no speech acquisition underwent MRI and Tc-99m ethyl cysteinate dimer SPECT... 
thyroid hormone | GENE | monocarboxylate transporter 8 deficiency | MUTATION | cerebral blood flow | CLINICAL PHENOTYPE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | MCT8 | SPECT | THYROID-HORMONE TRANSPORTER
Journal Article
REVISTA DE NEUROLOGIA, ISSN 0210-0010, 06/2013, Volume 56, Issue 12, pp. 615 - 622
Introduction. MCT8 is a specific transporter for the 14 and T3 thyroid hormones that allows their entry in the brain and other organs. Mutations in MCT8... 
Allan-Herndon-Dudley syndrome | HERNDON-DUDLEY-SYNDROME | Delayed myelination | Pelizaeus-Merzbacher disease | Leukodystrophy | CLINICAL NEUROLOGY | RETARDATION | GENE | DISEASE | Thyroid hormone transporter | Thyroid hormones | MUTATIONS | SLC16A2 | EXPRESSION | MCT8 | BRAIN | Muscle Hypotonia - surgery | Genetic Diseases, X-Linked - surgery | Monocarboxylic Acid Transporters - deficiency | Humans | Mental Retardation, X-Linked - surgery | Nystagmus, Pathologic - genetics | Child, Preschool | Thyroxine - blood | Male | Mental Retardation, X-Linked - drug therapy | Intellectual Disability - genetics | Muscle Hypotonia - diagnosis | Mental Retardation, X-Linked - genetics | Genetic Diseases, X-Linked - drug therapy | Biological Transport | Mental Retardation, X-Linked - diagnosis | Muscular Atrophy - diagnosis | Genetic Diseases, X-Linked - genetics | Monocarboxylic Acid Transporters - chemistry | Monocarboxylic Acid Transporters - physiology | Diagnosis, Differential | Dystonic Disorders - genetics | Muscle Hypotonia - genetics | Mental Retardation, X-Linked - pathology | Muscular Atrophy - pathology | Anticonvulsants - therapeutic use | Exons - genetics | Genotype | Muscular Atrophy - genetics | Pelizaeus-Merzbacher Disease - diagnosis | Muscular Atrophy - drug therapy | Genetic Diseases, X-Linked - diagnosis | Cord Blood Stem Cell Transplantation | Muscular Atrophy - surgery | Triiodothyronine - blood | Magnetic Resonance Imaging | Muscle Hypotonia - pathology | Point Mutation | Muscle Hypotonia - drug therapy | Brain - pathology | Genetic Diseases, X-Linked - pathology | Monocarboxylic Acid Transporters - genetics | Amino Acid Substitution
Journal Article
Journal Article
European Thyroid Journal, ISSN 2235-0640, 07/2012, Volume 1, Issue 2, pp. 72 - 79
Thyroid hormone (TH) metabolism and action via binding to nuclear receptors are intracellular events that require the passage of TH across the plasma membrane.... 
Basic Thyroidology / Review | Allan-Herndon-Dudley syndrome | Basic Thyroidology | Monocarboxylate transporter 8 (Mct8, Slc16a2) | Mct10 | Deiodinases | Oatp1c1 | Review
Journal Article
Journal Article