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Seminars in cancer biology, ISSN 1044-579X, 07/2019
Apoptosis and autophagy play seminal roles in maintaining organ homeostasis. Apoptosis represents canonical type I programmed cell death. Autophagy is viewed... 
Journal Article
by Deng, LL and Fan, J and Ding, YD and Yang, X and Huang, B and Hu, ZG
JOURNAL OF CANCER, ISSN 1837-9664, 2020, Volume 11, Issue 5, pp. 1017 - 1026
Background: Breast cancer is a heterogeneous disease with high aggression and novel targeted therapeutic strategies are required. Oncolytic vaccinia virus is... 
ADENOVIRAL TRANSFER | CELLS | MDA-7/IL-24 | ONCOLYTIC POXVIRUS | breast cancer | gene therapy | apoptosis | DIFFERENTIATION-ASSOCIATED GENE-7 | ANTITUMOR-ACTIVITY | interleukin-24 | oncolytic vaccinia virus | IN-VITRO | ONCOLOGY | GROWTH | MDA-7 IL-24
Journal Article
Immunological Investigations, ISSN 0882-0139, 05/2018, Volume 47, Issue 4, pp. 335 - 350
Induction of apoptosis or quiescent hepatic stellate cells (HSCs) can be an attractive molecular strategy due to the importance of activation of HSCs during... 
senescence | LX-2 | human hepatic stellate cells | IL-24/mda-7 | RGD peptide | Apoptosis | MDA-7/IL-24 | ACTIVATION | LIVER FIBROSIS | PROLIFERATION | IL-24 | IMMUNOLOGY | HEPATOCELLULAR-CARCINOMA | GENES | mda-7 | EXTRACELLULAR-MATRIX | MDA-7 IL-24 | EXPRESSION
Journal Article
MOLECULAR CANCER RESEARCH, ISSN 1541-7786, 11/2019, Volume 17, Issue 11, pp. 2221 - 2232
Nuclear receptor 4A1 (NR4A1, Nur77) is overexpressed in rhabdomyosarcoma (RMS), and inactivation of NR4A1 (siNR4A1) or treatment with the NR4A1 antagonist... 
ALVEOLAR | SURVIVAL | APOPTOSIS | MDA-7/IL-24 | GENE | ONCOLOGY | PANCREATIC-CANCER CELL | NUCLEAR RECEPTORS | PERK-DEPENDENT REGULATION | EXPRESSION | CHILDHOOD | CELL BIOLOGY
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2008, Volume 121, Issue 5, pp. 1108 - 1111
Cytokines are involved in virtually every aspect of immunity and inflammation. A cascade of responses evolves after cytokine activation, although optimal... 
Allergy and Immunology | cytokine | IL-10–related cytokines | IL-10-related cytokines | IFN-LAMBDA | MDA-7/IL-24 | RECEPTOR | PROLIFERATION | INDUCTION | IMMUNOLOGY | INTERLEUKIN-20 | ALLERGY | ASTHMA | POTENTIAL ROLE | T-CELLS | Signal Transduction - physiology | Animals | Interleukins - physiology | Humans | Cytokines - physiology | Interleukin-10 - physiology | Psoriasis | Cytokines | Kinases | Genes | Immune system
Journal Article
Oncogene, ISSN 0950-9232, 11/2003, Volume 22, Issue 54, pp. 8758 - 8773
Subtraction hybridization identified melanoma differentiation associated gene-7, mda-7, in the context of terminally differentiated human melanoma cells. Based... 
mda-7/IL-24 | Bcl-2 protein family | Prostate cancer | Apoptosis | Cancer gene therapy
Journal Article
Journal Article
Journal Article
Molecular Cancer, ISSN 1476-4598, 01/2017, Volume 16, Issue 1, p. 17
Journal Article
Translational Oncology, ISSN 1936-5233, 03/2019, Volume 12, Issue 3, pp. 453 - 461
The interleukin-24 (IL-24), a member of the IL-10–related cytokine gene family, is well known for its tumor suppressor activity in a broad spectrum of human... 
MELANOMA DIFFERENTIATION | APOPTOSIS | MDA-7/IL-24 | IRGD | ONCOLOGY | CELL
Journal Article
Planta Medica, ISSN 0032-0943, 03/2019, Volume 85, Issue 5, pp. 394 - 405
Abstract Damulin B, a dammarane-type saponin from steamed Gynostemma pentaphyllum , exhibits the strongest activity against human lung carcinoma A549 cells... 
Biological and Pharmacological Activity | MATRIX | MDA-7/IL-24 | CHEMISTRY, MEDICINAL | damulinB | STATISTICS | MITOCHONDRIA | MEDIATED APOPTOSIS | PLANT SCIENCES | lung cancer | Curcubitaceae | SAPONINS | PATHWAY | INTEGRATIVE & COMPLEMENTARY MEDICINE | saponin | Gynostemma pentaphyllum | PHARMACOLOGY & PHARMACY | CYTOCHROME-C RELEASE | PROTEINS | cytotoxicity | CYCLE
Journal Article
Journal Article
Advances in Cancer Research, ISSN 0065-230X, 01/2018, Volume 138, pp. 143 - 182
Journal Article
by Zhang, Y and Liu, Y and Xu, YC
FRONTIERS IN ONCOLOGY, ISSN 2234-943X, 12/2019, Volume 9, p. 1401
Interleukin (IL)-24 plays a potential anti-tumor activity in colorectal cancer in a dose-dependent manner. However, the immunoregulatory role of IL-24 to... 
T lymphocytes | anti-tumor | MDA-7/IL-24 | colorectal cancer | ONCOLOGY | immunoregulation | CANCER STATISTICS | DIFFERENTIATION | IL-24 | ANTICANCER IMMUNITY | interleukin-24 | MODULATION | Adenocarcinoma | Care and treatment | Interleukins | T cells | Colorectal cancer
Journal Article
OncoImmunology, ISSN 2162-402X, 05/2019, Volume 8, Issue 5, p. e1577126
CYTL1 is a novel cytokine that was first identified in CD34 + hematopoietic cells. We previously prepared recombinant CYTL1 and verified that it chemoattracted... 
cytokine | CYTL1 | tumor metastasis | STAT3 | MIGRATION | MDA-7/IL-24 | PROTEIN | CYTOKINE-LIKE 1 | PROLIFERATION | IMMUNOLOGY | PEPTIDE | CARTILAGE | INVASION | ONCOLOGY | SIGNALING PATHWAY | EXPRESSION
Journal Article