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European Journal of Immunology, ISSN 0014-2980, 11/2013, Volume 43, Issue 11, pp. 2930 - 2942
Tumor growth coincides with an accumulation of myeloid‐derived suppressor cells ( MDSC s), which exert immune suppression and which consist of two main... 
Polymorphonuclear MDSC (PMN‐MDSC) | T‐cell activation | Monocytic myeloid‐derived suppressor cell (MO‐MDSC) | CD8 | Nitric oxide | + | T‐cell suppression | Polymorphonuclear MDSC (PMN-MDSC) | Monocytic myeloid-derived suppressor cell (MO-MDSC) | T-cell suppression | T-cell activation | CTL SUPPRESSION | SUBPOPULATIONS | IFN-GAMMA | SELECTIN | IMMUNOLOGY | CD8(+) T-cell activation | NITRIC-OXIDE | DIFFERENTIATION | BEARING MICE | TRANSCRIPTION FACTOR | EXPRESSION | CD8(+) T-cell suppression | ANTIGEN | Up-Regulation | Cell Proliferation | Antigens, CD - biosynthesis | Membrane Glycoproteins - biosynthesis | Lectins, C-Type - biosynthesis | fas Receptor - biosynthesis | L-Selectin - biosynthesis | Receptor, Macrophage Colony-Stimulating Factor - metabolism | STAT5 Transcription Factor - metabolism | Signal Transduction - immunology | Lymphocyte Activation - immunology | STAT1 Transcription Factor - metabolism | Interferon Regulatory Factor-1 | Myeloid Cells - immunology | Antigens, Ly - metabolism | Female | Granzymes - biosynthesis | Interleukin-2 - metabolism | Cell Line | Mice, Inbred C57BL | Neutrophils - immunology | Hyaluronan Receptors - biosynthesis | Mice, Knockout | Cell Adhesion - immunology | Animals | Apoptosis - immunology | Interleukin-2 Receptor alpha Subunit - metabolism | Neoplasms - immunology | Mice | Antigens, Differentiation, T-Lymphocyte - biosynthesis | CD11b Antigen - metabolism | CD8-Positive T-Lymphocytes - immunology | Nitric Oxide - metabolism | Interferon-gamma - biosynthesis | T cells | Tumors | Cytotoxicity | T cell receptors | Immunology | Index Medicus
Journal Article
Methods in Enzymology, ISSN 0076-6879, 2019
Despite advances in uncovering the molecular mechanisms that mediate glioma progression and the implementation of novel therapeutic modalities, patients'... 
MDSCs | Immunosuppression | T-cell inhibition | Tumor microenvironment
Journal Article
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 70, pp. 114554 - 114567
Although myeloid-derived suppressor cells (MDSCs) have been demonstrated to contribute to tumor initiation, progression and metastasis, however, which MDSC... 
MDSCs | Breast cancer | T cells exhaustion | EMT | CXCR2 | Tumor metastasis | RECRUITMENT | METASTASIS | MECHANISM | STATISTICS | breast cancer | CXCR2(+) MDSCs | CELL BIOLOGY | EPITHELIAL-MESENCHYMAL TRANSITION | CROSS-TALK | RESISTANCE | tumor metastasis | SUPPRESSOR-CELLS | BLOCKADE | TUMOR-GROWTH
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 11/2019, Volume 143, pp. 260 - 274
Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease characterized by multi-organ injury. However, whether myeloid-derived... 
MDSCs | Senescence | TLR7 | Dihidroartemisinin | Systemic lupus erythematosus | Nrf2 | Index Medicus
Journal Article
Journal Article
Journal of immunology (Baltimore, Md. : 1950), ISSN 0022-1767, 7/2018, Volume 201, Issue 1, pp. 264 - 277
Tumor cells respond to IFNγ of activated T cells to up-regulate PD-L1 in the tumor microenvironment as an adaptive immune resistance mechanism. Tumor cells... 
MDSCs | PD-L1 | autocrine Type I interferon | IFNAR1
Journal Article
by Zhang, GB and Huang, HT and Zhu, YB and Yu, GH and Gao, X and Xu, YY and Liu, CP and Hou, JQ and Zhang, XG
ONCOIMMUNOLOGY, ISSN 2162-402X, 02/2015, Volume 4, Issue 2, pp. e977164 - e977164
Myeloid-derived suppressor cells (MDSC) potently inhibit antitumor immune responses, and thereby promoti tumor progression and metastasis. However, the nature... 
non-small cell lung cancer | CARCINOMA PATIENTS | ACTIVATION | MDSC | Tumor microenvironment | Treg | TUMOR | IMMUNOLOGY | CANCER | MELANOMA | ONCOLOGY | B7-H3 | MICE | EXPRESSION | T-CELLS | BLOOD
Journal Article
OncoImmunology, ISSN 2162-4011, 06/2017, Volume 6, Issue 6, pp. e1320011 - e1320011
CD39/CD73-adenosine pathway has been recently defined as an important tumor-induced immunosuppressive mechanism. We here documented a fraction of CD11b + CD33... 
CD39 | MDSCs | TGF-β | CD73 | NSCLC
Journal Article
European journal of immunology, ISSN 0014-2980, 6/2018, Volume 48, Issue 6, pp. 1059 - 1073
Endometriosis affects women in reproductive age with unclear immunological mechanism. Myeloid-derived suppressor cells (MDSCs) are a heterogeneous group of... 
chemokine | myeloid-derived suppressor cells (MDSCs) | angiogenesis | endometriosis | immunosuppression
Journal Article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, ISSN 1422-0067, 04/2019, Volume 20, Issue 8, p. 1916
Journal Article
Cancer Letters, ISSN 0304-3835, 11/2014, Volume 354, Issue 2, pp. 407 - 416
Pancreatic cancer is an aggressive malignancy and unresponsive to conventional chemotherapies. Here, the anti-inflammatory and anti-tumor effects of embelin on... 
MDSCs | Inflammation | Embelin | Pancreatic cancer | IL-6
Journal Article
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 09/2019, Volume 203, Issue 5, pp. 1095 - 1103
Myeloid-derived suppressor cells (MDSCs) are immature suppressive cells found in tumors and immunological niches. In this article, we highlight the ability of... 
MDSCS | TGF-BETA | CD4(+) T-CELLS | INTESTINAL TUMORIGENESIS | GENERATION | MICE | DIFFERENTIATION | ACCUMULATION | IMMUNOLOGY | PROGRESSION | TH17 CELLS
Journal Article
International Immunopharmacology, ISSN 1567-5769, 07/2011, Volume 11, Issue 7, pp. 779 - 779
Journal Article
The FEBS Journal, ISSN 1742-464X, 08/2017, Volume 284, Issue 15, pp. 2410 - 2424
Myeloid‐derived suppressor cells ( MDSC s), including granulocytic (G)‐ MDSC s and monocytic (M)‐ MDSC s, play a critical role in tumor‐induced T cell... 
miR‐30a | SOCS | MDSC | B cell lymphoma | miR-30a | SOCS3 | M-MDSCs | G-MDSCs | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | STAT3 | MYELOID CELLS | MICRORNA-155 | MESENCHYMAL STEM-CELLS | DEFICIENCY | GROWTH | NON-HODGKIN-LYMPHOMA | SUPPRESSOR-CELLS | TUMOR MICROENVIRONMENT | Neoplasm Transplantation | Up-Regulation | MicroRNAs - antagonists & inhibitors | Lymphoma, B-Cell - therapy | Arginase - metabolism | Gene Expression Regulation, Neoplastic | Monocyte-Macrophage Precursor Cells - immunology | MicroRNAs - metabolism | CD4-Positive T-Lymphocytes - pathology | Neoplasm Proteins - metabolism | Monocyte-Macrophage Precursor Cells - metabolism | CD4-Positive T-Lymphocytes - immunology | Myeloid-Derived Suppressor Cells - cytology | Lymphoma, B-Cell - immunology | Cell Differentiation | 3' Untranslated Regions | Neoplasm Proteins - genetics | Spleen - pathology | Myeloid-Derived Suppressor Cells - metabolism | Granulocyte Precursor Cells - immunology | Myeloid-Derived Suppressor Cells - pathology | Lymphoma, B-Cell - metabolism | Myeloid-Derived Suppressor Cells - immunology | Granulocyte Precursor Cells - metabolism | Bone Marrow Cells - pathology | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Arginase - genetics | Suppressor of Cytokine Signaling 3 Protein - genetics | Granulocyte Precursor Cells - pathology | Immunosuppression | Monocyte-Macrophage Precursor Cells - pathology | Animals | Lymphoma, B-Cell - pathology | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Suppressor of Cytokine Signaling 3 Protein - metabolism | Lymphomas | RNA | T cells | Cell differentiation | Analysis | Transcription | MiRNA | Arginase | Lymphocytes T | Gene expression | Suppressor cells | Lymphoma | Immunological tolerance | Monocytes | Molecular modelling | Transfection | SOCS-3 protein | 3' Untranslated regions | Lymphocytes B | Ribonucleic acids | Rodents | Janus kinase | Differentiation | B-cell lymphoma | Index Medicus
Journal Article