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Neurobiology of disease, ISSN 0969-9961, 08/2014, Volume 68, Issue 100, pp. 66 - 77
Abstract Rett syndrome (RTT) is a rare neurodevelopmental disorder affecting almost exclusively females, caused in the overwhelming majority of the cases by... 
Neurology | Lipid peroxidation | Oxidative stress | Brain damage | Neurodevelopmental disorder | Murine models | Rett syndrome | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Arachidonic Acid - metabolism | Rett Syndrome - complications | Gas Chromatography-Mass Spectrometry | Mice, Inbred C57BL | Neuroprostanes - metabolism | Oxidative Stress - physiology | Male | Mice, Transgenic | Aldehydes - metabolism | Mutation - genetics | Methyl-CpG-Binding Protein 2 - genetics | Animals | Isoprostanes - metabolism | Analysis of Variance | Nestin - genetics | Brain Injuries - blood | Female | Mice | Brain Injuries - etiology | Rett Syndrome - blood | Rett Syndrome - genetics | Brain Injuries - pathology | Disease Models, Animal | Docosahexaenoic Acids - metabolism | Models | Analysis | Protein binding | Index Medicus | Organic chemistry | Chemical Sciences | OS, oxidative stress | Mecp2 | y, hemizygous null mice | NPBI, non-protein-bound iron | Mecp2, methyl-CpG-binding protein 2 — mouse protein | CRE, Cre-Recombinase | AdA, adrenic acid | AUs, arbitrary units | ARA, arachidonic acid | 4-HNE PAs, 4-HNE protein adducts | PSV, Preserved Speech Variant | Mecp2, methyl-CpG-binding protein 2 — mouse gene | wt, wild type | wt-Cre, wild type expressing Cre recombinase | MECP2, methyl-CpG-binding protein 2 — human gene | y, symptomatic Mecp2 308-mutated hemizygous males | ROS, reactive oxygen species | F2-IsoPs, F2-isoprostanes | MeCP2, methyl-CpG-binding protein 2 — human protein | y, Lox | F2-dihomo-IsoPs, F2-dihomo-isoprostanes | 4-HNE PAs, 4-hydroxy-2-nonenal protein adducts | Mecp2 stop | y NestinCre, rescued Lox | ASDs, autism spectrum disorders | F4-NeuroPs, F4-neuroprostanes | Mecp2 308 | stop pre-symptomatic hemizygous mice | x, symptomatic Mecp2 308-mutated females | DHA, docosahexaenoic acid | PUFAs, polyunsaturated fatty acids | BDNF, brain-derived neurotrophic factor | IsoPs, isoprostanes | RTT, Rett syndrome | stop mice (Mecp2 reactivated in the nervous tissue) | 4-HNE, 4-hydroxy-2-nonenal
Journal Article
Molecular neurobiology, ISSN 1559-1182, 12/2018, Volume 56, Issue 7, pp. 5188 - 5201
Journal Article
Molecular neurobiology, ISSN 0893-7648, 7/2019, Volume 56, Issue 7, pp. 4838 - 4854
Journal Article
Epigenetics, ISSN 1559-2308, 10/2014, Volume 1, Issue 4, pp. 172 - 182
Mutations in MECP2, encoding methyl CpG binding protein 2 (MeCP2), cause most cases of Rett syndrome (RTT), an X-linked neurodevelopmental disorder. Both RTT... 
Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | DNA methylation | Autism | MeCP2 | Neurodevelopmental disorders | Rett syndrome | Biochemistry & Molecular Biology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Index Medicus
Journal Article
Journal Article
REVIEW ARTICLE - Neurological, genetic and epigenetic features of Rett syndrome, 10/2004
Rett syndrome (RTT) is a severe neurodevelopmental disorder associated with mutations in the X-linked gene encoding methyl-CpG-binding protein 2 (MECP2).... 
Neurology | Pediatrics | Rett syndrome, MECP2 mutations, X chromosome inactivation, genotype-phenotype correlations. pn04037
Journal
F1000 research, ISSN 2046-1402, 03/2018, Volume 7, pp. 398 - 398
Rett Syndrome is a severe neurological disorder mainly due to mutations in the methyl-CpG-binding protein 2 gene ( ). Mecp2 is known to play a role in... 
Mecp2 | Treatment | Rett syndrome | Chromatin | Animal models | Transcription | Neuropathology | Intellectual disabilities | Medical innovations | Gene regulation | Clinical trials | Studies | Proteins | Genotype & phenotype | Molecular modelling | Methyl-CpG binding protein | MeCP2 protein | DNA methylation | Ataxia | Mutation | Gene therapy | Deoxyribonucleic acid--DNA | CpG islands
Journal Article
Brain, behavior, and immunity, ISSN 0889-1591, 02/2017, Volume 60, pp. 106 - 116
Rett syndrome (RTT) is a neurodevelopmental disorder caused by loss-of-function mutations in the gene encoding MeCP2, an epigenetic modulator that binds the... 
MeCP2 | CR1 | Rett syndrome | Microglia
Journal Article