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Molecular Cancer Therapeutics, ISSN 1535-7163, 05/2018, Volume 17, Issue 5, pp. 1024 - 1038
Ligation of OX40 (CD134, TNFRSF4) on activated T cells by its natural ligand (OX40L, CD252, TNFSF4) enhances cellular survival, proliferation, and effector... 
EFFECTOR | ONCOLOGY | BLOCKS | EXPANSION | REGULATORY T-CELLS | COSTIMULATION | SUPPRESSION | CD134 | CUTTING EDGE | Recombinant Fusion Proteins - immunology | T-Lymphocytes, Regulatory - metabolism | Receptors, OX40 - agonists | OX40 Ligand - genetics | Recombinant Fusion Proteins - pharmacology | Immunoglobulin Fc Fragments - metabolism | OX40 Ligand - metabolism | Humans | Protein Multimerization - immunology | Macaca mulatta | Receptors, OX40 - immunology | T-Lymphocytes, Regulatory - immunology | Lymphocyte Activation - immunology | Receptors, OX40 - metabolism | Immunoglobulin Fc Fragments - immunology | T-Lymphocytes - metabolism | Immunoglobulin G - immunology | HEK293 Cells | Female | Cytotoxicity, Immunologic - drug effects | Cytokines - immunology | Cytokines - metabolism | Recombinant Fusion Proteins - chemistry | Animals | Immunoglobulin G - genetics | OX40 Ligand - immunology | Lymphocyte Activation - drug effects | Cell Line, Tumor | T-Lymphocytes - immunology | Cytotoxicity, Immunologic - immunology | Immunoglobulin Fc Fragments - genetics | Immunoglobulin G - metabolism | Cytolytic activity | Cell proliferation | Toxicity | CD8 antigen | Cytotoxicity | Lymphocytes T | Immunity | Proteins | Receptors | Cell growth | Lymphocytes | Peripheral blood | Primates | CD25 antigen | Fusion protein | Recombinant | Immunological memory | Memory cells | Cell survival | Cytokines | Immunomodulation | T cell receptors | CD134 antigen | CD4 antigen | Fc receptors | Ox40L protein | Lymphocytes B | Tumor necrosis factor | Ligands | Tumors | OX40 | fusion protein | OX40 ligand | MEDI6383 | immunotherapy
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