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Developmental Biology, ISSN 0012-1606, 2006, Volume 297, Issue 1, pp. 238 - 248
Palatal fusion is a complex, multi-step developmental process; the consequence of failure in this process is cleft palate, one of the most common birth defects... 
TGF-β signaling | Palatogenesis | Irf6 | Proliferation | Medial edge epithelium (MEE) | Epithelial–mesenchymal transformation (EMT) | Apoptosis | Epithelial-mesenchymal transformation (EMT) | CONDITIONAL INACTIVATION | DIFFERENTIAL EXPRESSION | proliferation | palatogenesis | apoptosis | DEVELOPMENTAL BIOLOGY | SUBMUCOUS CLEFT-PALATE | epithelial-mesenchymal transformation (EMT) | MESENCHYMAL TRANSFORMATION | MATRIX METALLOPROTEINASES | TGF-beta signaling | TOOTH DEVELOPMENT | CRANIAL NEURAL CREST | CRANIOFACIAL DEVELOPMENT | TRANSFORMING GROWTH FACTOR-BETA-3 | medial edge epithelium (MEE) | DEVELOPMENTAL EXPRESSION | Receptors, Transforming Growth Factor beta - genetics | Cell Proliferation | Signal Transduction | Protein-Serine-Threonine Kinases | Interferon Regulatory Factors - metabolism | Interferon Regulatory Factors - genetics | Mice, Transgenic | Cleft Palate - genetics | Mesoderm - cytology | Palate - embryology | Epithelium - embryology | Animals | Transforming Growth Factor beta - genetics | Receptors, Transforming Growth Factor beta - metabolism | Gene Expression Regulation, Developmental | Epithelium - physiology | Mice | Apoptosis - physiology | Palate - cytology | Transforming Growth Factor beta3 | Transforming Growth Factor beta - metabolism | Disease Models, Animal | Palate | Biochemistry | Research | Mammals | Growth | Developmental biology | Birth defects | Transforming growth factors | Epithelium | Analysis
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 07/2009, Volume 107, Issue 4, pp. 818 - 825
TGF‐β3, TβR‐I, and TGF‐β‐activated Smad2 has been suggested to be a series of signaling molecules for secondary palate fusion. In this article, we show that a... 
TGF‐β3 | apoptosis | βig‐h3 | medial edge epithelium (MEE) | RGD | palate | cleft | antisense | Cleft | Antisense | Palate | Medial edge epithelium (MEE) | TGF-β3; βig-h3 | Apoptosis | APOPTOSIS | CLEFT-PALATE | MEDIAL EDGE EPITHELIUM (MEE) | DEFECTS | TGF-beta 3 | SECONDARY PALATE | INTEGRIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTISENSE | PALATE | IDENTIFICATION | CELL-DEATH | CELL BIOLOGY | ADHESION | MUTANT MICE | CLEFT | CRANIAL SUTURE MORPHOGENESIS | EXPRESSION | beta ig-h3
Journal Article
DEVELOPMENT, ISSN 0950-1991, 01/1998, Volume 125, Issue 1, pp. 95 - 105
Epithelial-mesenchymal transformation plays an important role in the disappearance of the midline line epithelial seam in rodent palate, leading to confluence... 
CELLS | DIFFERENTIAL EXPRESSION | FUSION | INVITRO | ORGAN-CULTURE | medial edge epithelium | DEVELOPMENTAL BIOLOGY | carboxyfluorescein | EPIDERMAL GROWTH-FACTOR | craniofacial morphogenesis | chicken palate development | RETINOIC ACID | AVIAN SECONDARY PALATE | EMBRYONIC HEART | epithelial-mesenchymal transformation | TGF-BETA RECEPTOR | TGF beta
Journal Article
Developmental Dynamics, ISSN 1058-8388, 07/1997, Volume 209, Issue 3, pp. 255 - 260
Studies on transforming growth factor β3 (TGF‐β3) deficient mice have shown that TGF‐β3 plays a critical role in palatogenesis. These null mutant mice have... 
palatal fusion | TGF‐β3 null mutation | medial edge epithelial cells | Medial edge epithelial cells | Palatal fusion | TGF-β3 null mutation
Journal Article
DEVELOPMENTAL DYNAMICS, ISSN 1058-8388, 07/1997, Volume 209, Issue 3, pp. 255 - 260
Studies on transforming growth factor beta 3 (TGF-beta 3) deficient mice have shown that TGF-beta 3 plays a critical role in palatogenesis. These null mutant... 
CLEFT-PALATE | DIFFERENTIAL EXPRESSION | TGF-BETA | PALATOGENESIS | K HY DEVELOPMENTAL BIOLOGY | DEVELOPMENTAL BIOLOGY | palatal fusion | FATE | TGF-beta 3 null mutation | medial edge epithelial cells
Journal Article
Journal Article
JOURNAL OF CELLULAR PHYSIOLOGY, ISSN 0021-9541, 06/2015, Volume 230, Issue 6, pp. 1212 - 1225
The periderm is a flat layer of epithelium created during embryonic development. During palatogenesis, the periderm forms a protective layer against premature... 
MESENCHYMAL TRANSFORMATION | MEDIAL EDGE EPITHELIUM | CLEFT-PALATE | PHYSIOLOGY | DIFFERENTIAL EXPRESSION | SEAM DISINTEGRATION | GROWTH | MOUSE | GENE-EXPRESSION | IRF6 | P63 | CELL BIOLOGY
Journal Article
HUMAN MOLECULAR GENETICS, ISSN 0964-6906, 11/2009, Volume 18, Issue 21, pp. 4171 - 4179
Craniofacial defects involving the lip and/or palate are among the most common human birth defects. X-linked cleft palate and ankyloglossia results from... 
TBX22 MUTATIONS | LIP | PLAYERS | EXPRESSION ANALYSIS | FUSION | FREQUENT CAUSE | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | GENETICS & HEREDITY | T-BOX GENE | MEDIAL-EDGE EPITHELIUM | CHARGE-SYNDROME
Journal Article
Cold Spring Harbor Perspectives in Biology, ISSN 1943-0264, 11/2017, Volume 9, Issue 11, p. a022269
Journal Article
DEVELOPMENTAL BIOLOGY, ISSN 0012-1606, 02/2011, Volume 350, Issue 2, pp. 511 - 519
The canonical Wnt/beta-catenin signaling plays essential role in development and diseases. Previous studies have implicated the canonical Wnt/beta-catenin... 
MEDIAL EDGE EPITHELIUM | CLEFT-PALATE | Cleft palate | SECONDARY PALATE | DEVELOPMENTAL BIOLOGY | Wnt/beta-catenin signaling | Palate fusion | E-CADHERIN | BETA-CATENIN | TOOTH | Tgf-beta 3 | HAIR-FOLLICLES | MICE | WNT | SONIC-HEDGEHOG
Journal Article