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Nature, ISSN 0028-0836, 03/2011, Volume 471, Issue 7340, pp. 591 - 596
Members of the tumour necrosis factor (TNF) receptor superfamily have important functions in immunity and inflammation. Recently linear ubiquitin chains... 
RHEUMATOID-ARTHRITIS | KAPPA-B ACTIVATION | CHRONIC PROLIFERATIVE DERMATITIS | K11-LINKED POLYUBIQUITINATION | STRUCTURAL BASIS | MULTIDISCIPLINARY SCIENCES | MICE | CHAINS | TNF | NEMO | MEDIATED REGULATION | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Inflammation - pathology | Skin - cytology | Skin - metabolism | Humans | Tumor Necrosis Factor-alpha - genetics | Ubiquitin - metabolism | NF-kappa B - metabolism | Tumor Necrosis Factor-alpha - deficiency | Multiprotein Complexes - metabolism | Inflammation - metabolism | Nerve Tissue Proteins - chemistry | Ubiquitination | CD40 Ligand - metabolism | I-kappa B Kinase - metabolism | Interleukin-1beta - metabolism | Carrier Proteins - chemistry | Receptors, Tumor Necrosis Factor - deficiency | Skin - pathology | Receptors, Tumor Necrosis Factor - genetics | Skin - immunology | Receptors, Tumor Necrosis Factor - metabolism | Cell Line | Signal Transduction | Ubiquitin - chemistry | Ubiquitin-Protein Ligases - metabolism | Immunity - immunology | Ubiquitin-Protein Ligases - chemistry | Nerve Tissue Proteins - genetics | Ubiquitin-Protein Ligase Complexes - chemistry | Nerve Tissue Proteins - metabolism | Multiprotein Complexes - chemistry | Phenotype | Animals | Carrier Proteins - metabolism | Ubiquitin-Protein Ligase Complexes - metabolism | Inflammation - prevention & control | Mice | Transcription Factors | Prevention | Tumor necrosis factor | Genes | Physiological aspects | Inflammation | Genetic aspects | Cellular signal transduction | Research | Ubiquitin-proteasome system | Proteins | Mutation | Disease | Apoptosis | Recruitment
Journal Article
by Tang, Y and Joo, D and Liu, GN and Tu, HL and You, J and Jin, JP and Zhao, XQ and Hung, MC and Lin, X
JOURNAL OF BIOLOGICAL CHEMISTRY, 12/2018, Volume 293, Issue 52, pp. 20062 - 20072
The linear ubiquitin chain assembly complex (LUBAC) regulates NF-B activation by modifying proteins with linear (M1-linked) ubiquitination chains. Although... 
RNF31 | tumor necrosis factor (TNF) | ACTIVATION | PROTEIN | cell death | cFLIP | BIOCHEMISTRY & MOLECULAR BIOLOGY | apoptosis | RECEPTOR | MEDIATED APOPTOSIS | LUBAC | caspase | CELL-DEATH | ubiquitylation (ubiquitination) | TUMOR-NECROSIS-FACTOR | SHARPIN | C-FLIP | EMBRYONIC LETHALITY | linear ubiquitination | NF-KAPPA-B
Journal Article
Scientific Reports, ISSN 2045-2322, 10/2016, Volume 6, Issue 1, p. 36135
Journal Article
Current Rheumatology Reports, ISSN 1523-3774, 7/2018, Volume 20, Issue 7, pp. 1 - 6
The nuclear factor κB (NF-κB) pathway is tightly regulated through multiple posttranslational mechanisms including ubiquitination. Mutations in these... 
Medicine & Public Health | Autoinflammatory disease | Rheumatology | NF-kB | OTULIN | Relopathy | LUBAC | A20 | CHAIN ASSEMBLY COMPLEX | ZINC-FINGER 7 | RHEUMATOLOGY | CELL-DEATH | NF-kappa B | MEDIATED LINEAR UBIQUITINATION | IKK-BETA SUBUNIT | IMMUNE-RESPONSES | POLYUBIQUITIN CHAINS | LIGASE COMPLEX | NF-KAPPA-B | SIGNALING COMPLEXES | Ubiquitin | Medicine, Experimental | Enzymes | Medical research
Journal Article
PLoS Pathogens, ISSN 1553-7366, 04/2015, Volume 11, Issue 4, p. e1004877
Journal Article