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1. Full Text Direct reprogramming of human fibroblasts toward a cardiomyocyte-like state
by Fu, Ji-Dong and Stone, Nicole R and Liu, Lei and Spencer, C. Ian and Qian, Li and Hayashi, Yohei and Delgado-Olguin, Paul and Ding, Sheng and Bruneau, Benoit G and Srivastava, Deepak
Stem cell reports, ISSN 2213-6711, 09/2013, Volume 1, Issue 3, pp. 235 - 247
Cell & Tissue Engineering | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Embryonic Stem Cells - metabolism | MEF2 Transcription Factors - genetics | Embryonic Stem Cells - cytology | Humans | T-Box Domain Proteins - biosynthesis | Gene Expression Regulation, Developmental - genetics | Cell Differentiation - genetics | Nuclear Proteins - biosynthesis | Trans-Activators - genetics | MEF2 Transcription Factors - biosynthesis | Trans-Activators - biosynthesis | Nuclear Proteins - genetics | Cellular Reprogramming - genetics | Fibroblasts - metabolism | GATA4 Transcription Factor - biosynthesis | Signal Transduction | GATA4 Transcription Factor - genetics | Transcription Factors - biosynthesis | Transcription Factors - genetics | DNA-Binding Proteins - genetics | T-Box Domain Proteins - genetics | Cell Lineage | Animals | Myocytes, Cardiac - metabolism | Mice | DNA-Binding Proteins - biosynthesis | Transforming Growth Factor beta - metabolism | Index Medicus
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2. Full Text Genome-wide identification of post-translational modulators of transcription factor activity in human B cells
by Rajbhandari, Presha and Shen, Qiong and Margolin, Adam A and Wang, Kai and Klein, Ulf and Dalla-Favera, Riccardo and Alvarez, Mariano J and Califano, Andrea and Nemenman, Ilya and Saito, Masumichi and Basso, Katia and Bisikirska, Brygida C and Lim, Wei Keat
Nature biotechnology, ISSN 1087-0156, 09/2009, Volume 27, Issue 9, pp. 829 - 837
Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Biotechnology | Biological and medical sciences | Diverse techniques | Molecular and cellular biology | Phosphorylation | Homeodomain Proteins - metabolism | Humans | Protein Processing, Post-Translational - genetics | Basic Helix-Loop-Helix Transcription Factors - metabolism | Microarray Analysis | Protein Stability | Histone Deacetylase 1 - genetics | B-Lymphocytes - metabolism | MEF2 Transcription Factors | Protein-Serine-Threonine Kinases - metabolism | Cell Line | Reproducibility of Results | Basic Helix-Loop-Helix Transcription Factors - genetics | Myogenic Regulatory Factors - genetics | Signal Transduction | MADS Domain Proteins - genetics | Protein-Serine-Threonine Kinases - genetics | B-Lymphocytes - physiology | Myogenic Regulatory Factors - metabolism | Transcription Factors - genetics | Proto-Oncogene Proteins c-myc - metabolism | Homeodomain Proteins - genetics | MADS Domain Proteins - metabolism | Transcription Factors - metabolism | Systems Biology - methods | Algorithms | Cell Line, Tumor | Models, Genetic | Proto-Oncogene Proteins c-myc - genetics | Histone Deacetylase 1 - metabolism | Post-translational modification | Transcription factors | Physiological aspects | Genetic aspects | B cells | Research | Properties | Signal transduction | Cellular biology | Genomics | Index Medicus
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3. Full Text MEF2 transcription factors are key regulators of sprouting angiogenesis
by Sacilotto, Natalia and Chouliaras, Kira M and Nikitenko, Leonid L and Lu, Yao Wei and Fritzsche, Martin and Wallace, Marsha D and Nornes, Svanhild and García-Moreno, Fernando and Payne, Sophie and Bridges, Esther and Liu, Ke and Biggs, Daniel and Ratnayaka, Indrika and Herbert, Shane P and Molnár, Zoltán and Harris, Adrian L and Davies, Benjamin and Bond, Gareth L and Bou-Gharios, George and Schwarz, John J and De Val, Sarah
Genes & development, ISSN 0890-9369, 10/2016, Volume 30, Issue 20, pp. 2297 - 2309
Dll4 regulation | MEF2 transcription factors | HLX regulation | Sprouting angiogenesis | Genetics & Heredity | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | MEF2 Transcription Factors - genetics | Humans | Intracellular Signaling Peptides and Proteins - metabolism | Vascular Endothelial Growth Factor A - metabolism | Retina - embryology | Gene Expression Regulation, Developmental | MEF2 Transcription Factors - chemistry | Membrane Proteins - metabolism | Protein Interaction Domains and Motifs | Intracellular Signaling Peptides and Proteins - genetics | Endothelial Cells - physiology | Histone Deacetylases - genetics | Signal Transduction | Membrane Proteins - genetics | Neovascularization, Physiologic - genetics | Cells, Cultured | Histone Deacetylases - metabolism | Zebrafish | Animals | Endothelial Cells - cytology | Embryo, Nonmammalian | MEF2 Transcription Factors - metabolism | Neovascularization, Pathologic - genetics | Enhancer Elements, Genetic - genetics | Mice | Endothelial Cells - enzymology | Transcription factors | Research | Neovascularization | Gene expression | Index Medicus | Research Paper | sprouting angiogenesis
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4. Full Text Mfn2 downregulation in excitotoxicity causes mitochondrial dysfunction and delayed neuronal death
by Martorell‐Riera, Alejandro and Segarra‐Mondejar, Marc and Muñoz, Juan P and Ginet, Vanessa and Olloquequi, Jordi and Pérez‐Clausell, Jeús and Palacín, Manuel and Reina, Manuel and Puyal, Julien and Zorzano, Antonio and Soriano, Francesc X
The EMBO journal, ISSN 0261-4189, 10/2014, Volume 33, Issue 20, pp. 2388 - 2407
neuron | excitotoxicity | transcriptional regulation | mitochondrial dynamics | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Dynamins - metabolism | MEF2 Transcription Factors - genetics | Calcium - metabolism | Humans | Homeostasis | Male | Mitochondrial Proteins - genetics | Mitochondrial Dynamics - physiology | Mitochondrial Proteins - metabolism | Cell Death | Neurons - physiology | Models, Animal | Membrane Proteins - metabolism | bcl-2-Associated X Protein - genetics | Cell Line | Membrane Proteins - genetics | Down-Regulation | Cells, Cultured | Gene Expression Regulation | bcl-2-Associated X Protein - metabolism | Dynamins - genetics | Rats | Rats, Sprague-Dawley | Animals | MEF2 Transcription Factors - metabolism | Mutation | Mitochondria - physiology | Mitochondria | Mitochondrial DNA | Toxicity | Neurons | Index Medicus | Neurodegenerative Diseases | Malalties neurodegeneratives | Mitocondris
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5. Full Text MEF2 transcription factors: Developmental regulators and emerging cancer genes
by Pon, Julia R and Marra, Marco A
Oncotarget, ISSN 1949-2553, 2016, Volume 7, Issue 3, pp. 2297 - 2312
MEF2 | Transcription factor | Developmental biology | Gene regulation | Cancer | Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cell Differentiation - genetics | Oncogenes - genetics | Cell Proliferation - genetics | MEF2 Transcription Factors - genetics | Animals | Neoplasms - genetics | Humans | Gene Expression Regulation, Developmental - genetics | Mice | Gene Expression Regulation, Neoplastic - genetics | Index Medicus
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6. Full Text MEF2C Transcription Factor Controls Chondrocyte Hypertrophy and Bone Development
by Arnold, Michael A and Kim, Yuri and Czubryt, Michael P and Phan, Dillon and McAnally, John and Qi, Xiaoxia and Shelton, John M and Richardson, James A and Bassel-Duby, Rhonda and Olson, Eric N
Developmental cell, ISSN 1534-5807, 2007, Volume 12, Issue 3, pp. 377 - 389
DEVBIO | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Cell physiology | Molecular and cellular biology | Cell differentiation, maturation, development, hematopoiesis | Chondrocytes - cytology | Cercopithecus aethiops | Gene Expression Regulation, Developmental - genetics | Male | Hypertrophy - metabolism | Cell Differentiation - genetics | Dwarfism - metabolism | Bone and Bones - metabolism | Cartilage - cytology | Hypertrophy - genetics | Female | Dwarfism - physiopathology | Chondrocytes - metabolism | MEF2 Transcription Factors | Osteogenesis - genetics | Bone and Bones - cytology | Cartilage - embryology | Histone Deacetylases - genetics | Myogenic Regulatory Factors - genetics | Neovascularization, Physiologic - genetics | Myogenic Regulatory Factors - metabolism | Mice, Transgenic | Cartilage - metabolism | Mutation - genetics | Dwarfism - genetics | Animals | Mice | Bone Development - genetics | Bone and Bones - embryology | COS Cells | Index Medicus
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7. Full Text Induction of diverse cardiac cell types by reprogramming fibroblasts with cardiac transcription factors
by Nam, Young-Jae and Lubczyk, Christina and Bhakta, Minoti and Zang, Tong and Fernandez-Perez, Antonio and McAnally, John and Bassel-Duby, Rhonda and Olson, Eric N and Munshi, Nikhil V
Development (Cambridge), ISSN 0950-1991, 11/2014, Volume 141, Issue 22, pp. 4267 - 4278
Direct reprogramming | Mouse | Pacemaker | Cardiomyocyte | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Immunohistochemistry | MEF2 Transcription Factors - genetics | Fibroblasts - physiology | Heart - embryology | DNA Primers - genetics | Basic Helix-Loop-Helix Transcription Factors - metabolism | Cell Differentiation - physiology | Real-Time Polymerase Chain Reaction | Fibroblasts - metabolism | Green Fluorescent Proteins - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | GATA4 Transcription Factor - metabolism | Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels - metabolism | Myocytes, Cardiac - cytology | Embryonic Induction - physiology | GATA4 Transcription Factor - genetics | Transcription Factors - genetics | T-Box Domain Proteins - genetics | T-Box Domain Proteins - metabolism | Action Potentials - physiology | Transcription Factors - metabolism | Animals | Analysis of Variance | Myocytes, Cardiac - physiology | MEF2 Transcription Factors - metabolism | Fibroblasts - cytology | Mice | Index Medicus | Stem Cells and Regeneration
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8. Full Text Tissue-specific splicing of a ubiquitously expressed transcription factor is essential for muscle differentiation
by Sebastian, Soji and Faralli, Hervé and Yao, Zizhen and Rakopoulos, Patricia and Palii, Carmen and Cao, Yi and Singh, Kulwant and Liu, Qi-Cai and Chu, Alphonse and Aziz, Arif and Brand, Marjorie and Tapscott, Stephen J and Dilworth, F.Jeffrey
Genes & development, ISSN 0890-9369, 02/2013, Volume 27, Issue 11, pp. 1247 - 1259
Mef2 | Alternative splicing | Ash2l | Gene expression | Hdac | PKA signaling | Genetics & Heredity | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | Alternative Splicing | Genome - genetics | DNA-Binding Proteins - metabolism | Cell Differentiation - genetics | Myogenic Regulatory Factors - chemistry | Organ Specificity - genetics | Phosphorylation - genetics | Protein Isoforms - metabolism | Chromatin Immunoprecipitation | Muscles - metabolism | MEF2 Transcription Factors | Cyclic AMP-Dependent Protein Kinases - metabolism | Myogenic Regulatory Factors - genetics | Gene Expression Regulation - genetics | Myogenic Regulatory Factors - metabolism | Exons - genetics | Nuclear Proteins - metabolism | Signal Transduction - genetics | Mutation - genetics | Transcription Factors - metabolism | Animals | Muscles - enzymology | Mice | Transcription, Genetic - genetics | Muscles - cytology | Protein Isoforms - genetics | Physiological aspects | Muscle cells | Chromatin | Analysis | Index Medicus | alternative splicing | Ash2L | Research Paper | gene expression | HDAC
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