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American Journal of Medical Genetics, Part A, ISSN 1552-4825, 03/2016, Volume 170, Issue 3, pp. 688 - 693
Journal Article
Circulation Research, ISSN 0009-7330, 06/2013, Volume 113, Issue 1, pp. 22 - 31
RATIONALE:The peptide ligand apelin and its receptor APJ constitute a signaling pathway with numerous effects on the cardiovascular system, including... 
HDAC4 | MEF2A | HDAC5 | MEF2C | Developmental biology | APJ | G proteins | Ga13 | Apelin | VASCULAR DEVELOPMENT | CARDIAC & CARDIOVASCULAR SYSTEMS | EMBRYONIC-DEVELOPMENT | developmental biology | G13 | ENDOGENOUS PEPTIDE LIGAND | TRANSCRIPTION FACTOR MEF2C | DEPENDENT NUCLEAR EXPORT | CARDIAC DEVELOPMENT | BLOOD-PRESSURE | IMMUNOCYTOCHEMICAL LOCALIZATION | PROTEIN-COUPLED RECEPTOR | PERIPHERAL VASCULAR DISEASE | KRUPPEL-LIKE FACTOR-2 | HEMATOLOGY | Phosphorylation | Male | Endocardium - metabolism | Intercellular Signaling Peptides and Proteins - physiology | Genes, Lethal | Gene Expression Regulation, Developmental | Female | Transcription, Genetic | Active Transport, Cell Nucleus | Fetal Heart - abnormalities | Cardiovascular System - embryology | MEF2 Transcription Factors | Receptors, G-Protein-Coupled - physiology | GTP-Binding Protein alpha Subunits, G12-G13 - physiology | Kruppel-Like Transcription Factors - biosynthesis | Signal Transduction | Endocardium - embryology | Mice, Inbred C57BL | Cardiovascular Abnormalities - genetics | Histone Deacetylases - metabolism | Myogenic Regulatory Factors - physiology | Cardiovascular Abnormalities - embryology | Adipokines | Mice, Knockout | Animals | Receptors, G-Protein-Coupled - deficiency | Endothelium, Vascular - metabolism | Apelin Receptors | Mice | Protein Processing, Post-Translational | Receptors, G-Protein-Coupled - genetics | Kruppel-Like Transcription Factors - genetics | Gα13
Journal Article
BBA - Gene Regulatory Mechanisms, ISSN 1874-9399, 2010, Volume 1799, Issue 5, pp. 429 - 441
Ca /calmodulin-dependent protein kinase II (CaMKII) and calcineurin (CaN) are positive regulators of cardiac hypertrophy, but the nature of cross-talk between... 
MEF2c | GATA4 | CaMKII | Calcineurin | Hypertrophy
Journal Article
Journal of Steroid Biochemistry and Molecular Biology, ISSN 0960-0760, 11/2016, Volume 164, pp. 277 - 280
Transcribed from the gene, sclerostin is an osteocyte-derived negative regulator of bone formation that inhibits osteoblastogenesis via antagonism of the Wnt... 
ECR5 | MEF2C | SOST | BAC | Osteocyte
Journal Article
Journal of Steroid Biochemistry and Molecular Biology, ISSN 0960-0760, 2015, Volume 148, pp. 132 - 137
Myogenic enhancer factor2 (Mef2) consists of a family of transcription factors involved in morphogenesis of skeletal, cardiac and smooth muscle cells. Among... 
AML | Monocytic differentiation | C/EBBβ | Mef2C | CD14 | Vitamin D | HL60 CELLS | VITAMIN-D | DNA-BINDING | ACTIVATION | PHOSPHORYLATION | MACROPHAGES | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION FACTOR MEF2C | D-3-INDUCED DIFFERENTIATION | ESTABLISHMENT | MAPK PATHWAYS | C/EBB beta | ENDOCRINOLOGY & METABOLISM
Journal Article
Clinical Chemistry and Laboratory Medicine (CCLM), ISSN 1434-6621, 02/2018, Volume 56, Issue 3, pp. 502 - 511
Journal Article
Molecular Cell, ISSN 1097-2765, 03/2018, Volume 69, Issue 6, pp. 1017 - 1027.e6
Journal Article
Journal Article
Circulation, ISSN 0009-7322, 08/2017, Volume 136, Issue 13, pp. 1233 - 1246
BACKGROUND—Correct gene expression programming of the cardiomyocyte underlies the normal functioning of the heart. Alterations to this can lead to the loss of... 
Heart failure | Heterochromatin | Epigenomics | Mouse | Histone methylation | EHMT2 protein | MEF2C protein | Hypertrophy | heart failure | METHYLATION | COMPLEX | CARDIAC & CARDIOVASCULAR SYSTEMS | CHROMATIN | hypertrophy | HEART-FAILURE | TRANSCRIPTION | epigenomics | EARLY EMBRYOGENESIS | EHMT2 protein, mouse | heterochromatin | histone methylation | MEF2C protein, mouse | CARDIAC-HYPERTROPHY | GENE-EXPRESSION | PERIPHERAL VASCULAR DISEASE | MICE | WEB SERVER | MEF2 Transcription Factors - genetics | Heart - physiology | Cardiomegaly - pathology | Male | Polycomb-Group Proteins - metabolism | Histone-Lysine N-Methyltransferase - antagonists & inhibitors | RNA - isolation & purification | Heterochromatin - metabolism | Transcription, Genetic | Epigenesis, Genetic - drug effects | RNA - metabolism | Histone-Lysine N-Methyltransferase - genetics | Myocytes, Cardiac - cytology | Mice, Inbred C57BL | Cells, Cultured | Enzyme Inhibitors - pharmacology | RNA - chemistry | Heart - diagnostic imaging | Mice, Knockout | Stroke Volume | Up-Regulation - drug effects | Animals | Myocytes, Cardiac - drug effects | Sequence Analysis, RNA | Histone-Lysine N-Methyltransferase - metabolism | Heart - drug effects | MEF2 Transcription Factors - metabolism | Myocytes, Cardiac - metabolism | Polycomb-Group Proteins - chemistry | Mice | Histones - metabolism | Cardiomegaly - metabolism
Journal Article