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Pathology - Research and Practice, ISSN 0344-0338, 10/2019, Volume 215, Issue 10, p. 152558
Glioma is a common and fatal intracranial tumor. Both miR-377 and lncRNA MEG3 are tumor suppressors. This study was performed to investigate the association... 
lncRNA MEG3 | microRNA-377 | Glioma | Migration | Invasion | GASTRIC-CANCER | GROWTH | IncRNA MEG3 | MIR-1297 | PATHOLOGY | P53
Journal Article
Oncology Reports, ISSN 1021-335X, 07/2018, Volume 40, Issue 1, pp. 39 - 48
The prognosis of patients with gastric cancer remains poor mainly due to distant metastasis. Maternally expressed gene 3 (MEG3), a long non-coding RNA... 
Cell Mobility | Epithelial-mesenchymal transition | Gastric cancer | MEG3/miR-21 | MEG3 | MIGRATION | gastric cancer | cell mobility | PROLIFERATION | REGULATING MIR-21 | MICRORNA-21 | ONCOLOGY | PATHWAY | GROWTH | RESISTANCE | epithelial-mesenchymal transition | miR-21 | PROMOTES | EXPRESSION | NONCODING RNA MEG3
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 01/2020, Volume 521, Issue 2, pp. 368 - 374
Chronic obstructive pulmonary disease (COPD) is a prevalent disease worldwide, mainly caused by cigarette smoking. Maternally expressed gene 3 (MEG3) functions... 
MEG3 | CSE | Inflammation | 16HBE | Proliferation | miR-218 | Apoptosis
Journal Article
Experimental Neurology, ISSN 0014-4886, 03/2020, Volume 325, p. 113139
Inflammasome contributes to ischemic brain injury by inducing pyroptosis and inflammation. The aim of this study is to unravel the mechanism of long non-coding... 
MEG3 | Cerebral ischemia-reperfusion injury | AIM2 | Pyroptosis | miR-485
Journal Article
Gene, ISSN 0378-1119, 01/2017, Volume 596, pp. 1 - 8
Journal Article
HEPATOLOGY, ISSN 0270-9139, 02/2017, Volume 65, Issue 2, pp. 604 - 615
Bile acids (BAs) play critical physiological functions in cholesterol homeostasis, and deregulation of BA metabolism causes cholestatic liver injury. The long... 
NUCLEAR RECEPTOR SHP | HOMEOSTASIS | ACTIVATION | PROTEIN | LNCRNA MEG3 | GENES | RESISTANCE | TARGETS | DIFFERENTIATION | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 02/2020, Volume 121, Issue 2, pp. 1801 - 1810
Valvulopathy is a familiar heart disease, which fearfully harms the health of the body. We studied the effects and mechanism of long noncoding RNA maternally... 
MEG3 | inflammatory damage | valvulopathy | TNF‐α | miR‐101a
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 04/2015, Volume 116, Issue 4, pp. 542 - 550
Journal Article
by Liu, Y and Yue, PR and Zhou, T and Zhang, FZ and Wang, HX and Chen, XQ
BIOMEDICINE & PHARMACOTHERAPY, ISSN 0753-3322, 09/2018, Volume 105, pp. 1232 - 1239
Background: Long non-coding RNA (LncRNA) MEG3 has been demonstrated as a tumor suppressor in various cancers, including thyroid carcinoma (TC). However, the... 
MEG3 | MEDICINE, RESEARCH & EXPERIMENTAL | APOPTOSIS | lncRNA | METASTASIS | PROMOTES CELL-PROLIFERATION | CATENIN | INVASION | Thyroid carcinoma I-1 radioactivity | PROSTATE-CANCER | miR-182 | PHARMACOLOGY & PHARMACY | SUPPRESSES | EXPRESSION | NONCODING RNA MEG3
Journal Article
European Review for Medical and Pharmacological Sciences, ISSN 1128-3602, 2018, Volume 22, Issue 23, pp. 8315 - 8323
The aim of this study was to explore whether maternally expressed gene 3 (MEG3) could facilitate the proliferation and migration of oral squamous cell... 
Cell proliferation | MEG3 | OSCC | MiR-21 | Cell migration
Journal Article
by Zhang, LL and Hu, D and Zou, LH
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, ISSN 1128-3602, 12/2018, Volume 22, Issue 23, pp. 8315 - 8323
OBJECTIVE: The aim of this study was to explore whether maternally expressed gene 3 (MEG3) could facilitate the proliferation and migration of oral squamous... 
MEG3 | Cell proliferation | OSCC | APOPTOSIS | METASTASIS | MiR-21 | PHARMACOLOGY & PHARMACY | PROLIFERATION | CANCER | Cell migration | NONCODING RNA MEG3
Journal Article
Neurochemistry International, ISSN 0197-0186, 01/2020, Volume 132, p. 104602
Oxidative stress (OS) is accused in pathogenesis of many diseases, including liver cirrhosis by many mechanisms. One of them is the disturbance of long non... 
MEG3 | Cirrhosis | Neuropathy | PAR2 | N-acetylcysteine
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 09/2018, Volume 504, Issue 1, pp. 123 - 128
Paclitaxel (PTX) is a first-line chemotherapy drug for advanced non-small cell lung cancer (NSCLC). The long-chain non-coding RNA maternally expressed gene 3... 
MEG3 | NSCLC | Paclitaxel | A549 | P53 | METASTASIS | BIOPHYSICS | STATISTICS | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROLIFERATION | CARCINOMA | NONCODING RNA MEG3 | Chemotherapy | Anopheles | RNA | Analysis | Genetic research | Lung cancer, Non-small cell | Tumor proteins | Apoptosis | Cancer
Journal Article
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, ISSN 1874-9399, 07/2019, p. 194396
Journal Article
by He, YQ and Luo, YH and Liang, BY and Ye, L and Lu, GX and He, WM
ONCOTARGET, ISSN 1949-2553, 09/2017, Volume 8, Issue 42, pp. 73282 - 73295
LncRNAs are emerging as integral functional and regulatory components of normal biological activities and are now considered as critically involved in the... 
MEG3 | PROMOTER HYPERMETHYLATION | LNCRNA MEG3 | TUMOR-SUPPRESSOR GENE | DOWN-REGULATION | apoptosis | AFFECTS CELL-PROLIFERATION | COMPETING ENDOGENOUS RNA | CELL BIOLOGY | maternally expressed gene 3 | GROWTH-FACTOR-BETA | long noncoding RNAs | LONG NONCODING RNA | IMPRINTED GENE | cancer | DECREASED EXPRESSION
Journal Article
by Dong, X and Wang, J and Li, T and Xu, YP and Li, SY
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, ISSN 1128-3602, 12/2018, Volume 22, Issue 23, pp. 8265 - 8272
OBJECTIVE: LncRNA MEG3 is involved in the pathogenesis of several types of cancers. While its participation and function network in colorectal (CR)... 
MEG3 | PREDICTS | TGF-beta 1 | Colorectal adenocarcinoma | SPHK1 | POOR-PROGNOSIS | RAS MUTATIONS | PHARMACOLOGY & PHARMACY | CANCER | NONCODING RNA MEG3
Journal Article
by Huang, MD and Hou, JK and Wang, YF and Xie, M and Wei, CC and Nie, FQ and Wang, ZX and Sung, M
MOLECULAR THERAPY, ISSN 1525-0016, 04/2017, Volume 25, Issue 4, pp. 1014 - 1026
Long noncoding RNAs (1ncRNAs) have emerged as important regulators in a variety of human diseases, including cancers. However, the biological function of these... 
TRANSCRIPTION FACTORS | MEG3 | MEDICINE, RESEARCH & EXPERIMENTAL | PROMOTES CELL-PROLIFERATION | STATISTICS | DOWN-REGULATION | P53 | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | POOR-PROGNOSIS | GROWTH | GENETICS & HEREDITY | EXPRESSION | BINDING
Journal Article
European Review for Medical and Pharmacological Sciences, ISSN 1128-3602, 2019, Volume 23, Issue 5, pp. 2062 - 2068
OBJECTIVE: Dysregulation of long non-coding RNAs (lncRNAs) is associated with human carcinogenesis. The aim of the study is to explore the biological functions... 
MEG3 | Epithelial-mesenchymal transition | Cell invasion | Laryngeal squamous cell carcinoma | MIGRATION | PHARMACOLOGY & PHARMACY | CANCER | PROGRESSION | NONCODING RNA MEG3
Journal Article
Experimental and Molecular Pathology, ISSN 0014-4800, 04/2019, Volume 107, pp. 102 - 109
Diabetic retinopathy (DR) is the serious complication of diabetes, which could lead to blindness. Inflammation and apoptosis are hallmark of DR, but mechanism... 
Diabetic retinopathy | Inflammation | miR-34a | lncRNA-MEG3 | SIRT1 | CERNA | PROLIFERATION | PATHOLOGY | CROSSTALK | NF-KAPPA-B | CANCER | NONCODING RNA MEG3 | Analysis | Blindness | Glucose | Ophthalmology | Dextrose | Apoptosis
Journal Article
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