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1. Full Text Spindle asymmetry drives non-Mendelian chromosome segregation
by Akera, Takashi and Chmátal, Lukáš and Trimm, Emily and Yang, Karren and Aonbangkhen, Chanat and Chenoweth, David M and Janke, Carsten and Schultz, Richard M and Lampson, Michael A
Science (American Association for the Advancement of Science), ISSN 0036-8075, 11/2017, Volume 358, Issue 6363, pp. 668 - 672
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Oocytes - cytology | Chromosome Segregation | Microtubules - metabolism | Tyrosine - metabolism | Animals | Spindle Apparatus - metabolism | Oocytes - metabolism | Female | cdc42 GTP-Binding Protein - metabolism | Meiosis | Mice | Gametes | Cdc42 protein | Meiotic drive | Cortex | Cell division | Machinery | Eggs | Signaling | Molecular modelling | Asymmetry | Genetics | Chromosomes | Index Medicus | Life Sciences | Subcellular Processes | Cellular Biology | Reproductive Biology
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2. Full Text PLK1 regulates spindle association of phosphorylated eukaryotic translation initiation factor 4E-binding protein and spindle function in mouse oocytes
by Severance, Ashley L and Latham, Keith E
American Journal of Physiology: Cell Physiology, ISSN 0363-6143, 11/2017, Volume 313, Issue 5, pp. C501 - C515
Phosphorylation | Meiosis | Eukaryotic initiation factor 4E-binding protein 1 | Chromosome segregation | Translational control | Oocyte meiotic spindle | Physiology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Phosphorylation - physiology | Proto-Oncogene Proteins - antagonists & inhibitors | Protein-Serine-Threonine Kinases - physiology | Mice, Inbred C57BL | Cells, Cultured | Phosphoproteins - antagonists & inhibitors | Phosphoproteins - metabolism | Hydrazones - pharmacology | Cell Cycle Proteins - antagonists & inhibitors | Animals | Oocytes - physiology | Adaptor Proteins, Signal Transducing - antagonists & inhibitors | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Proto-Oncogene Proteins - physiology | Female | Mice | Thiazoles - pharmacology | Adaptor Proteins, Signal Transducing - metabolism | Spindle Apparatus - physiology | Cell Cycle Proteins - physiology | Physiological aspects | Binding proteins | Phosphotransferases | Chromosomes | Genetic translation | Protein binding | TOR protein | Translation | Polo-like kinase 1 | Translation initiation | Rapamycin | Cells | Oocytes | Proteins | Eukaryotes | Rodents | Metaphase | Polo-like kinase | Cytoskeleton | Ataxia telangiectasia mutated protein | Initiation factor eIF-4E | Spindles | Binding sites | Index Medicus | oocyte meiotic spindle | meiosis | eukaryotic initiation factor 4E-binding protein 1 | translational control | chromosome segregation | phosphorylation
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3. Full Text Live birth derived from oocyte spindle transfer to prevent mitochondrial disease
by Zhang, John and Liu, Hui and Luo, Shiyu and Lu, Zhuo and Chávez-Badiola, Alejandro and Liu, Zitao and Yang, Mingxue and Merhi, Zaher and Silber, Sherman J and Munné, Santiago and Konstandinidis, Michalis and Wells, Dagan and Huang, Taosheng
Reproductive biomedicine online, ISSN 1472-6483, 2017, Volume 34, Issue 4, pp. 361 - 368
Obstetrics and Gynecology | Nuclear transfer | Mitochondria | Leigh syndrome | Meiotic spindle | Oocyte | Cytoplasm | Life Sciences & Biomedicine | Obstetrics & Gynecology | Reproductive Biology | Science & Technology | Oocytes - ultrastructure | Mitochondrial Replacement Therapy | Humans | Live Birth | Preimplantation Diagnosis | Leigh Disease - genetics | Sequence Analysis, DNA | Pregnancy | Fertilization in Vitro | Pedigree | Female | Heterozygote | Oocyte Donation | DNA, Mitochondrial - chemistry | Leigh Disease - prevention & control | Maternal Inheritance | Index Medicus
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4. Full Text Kif2a Scales Meiotic Spindle Size in Hymenochirus boettgeri
by Miller, Kelly E and Session, Adam M and Heald, Rebecca
Current biology, ISSN 0960-9822, 11/2019, Volume 29, Issue 21, pp. 3720 - 3727.e5
katanin | TPX2 | kif2a | Hymenochirus boettgeri | Xenopus laevis | Xenopus tropicalis | sub cellular scaling | egg extract | meiotic spindle | Biochemistry & Molecular Biology | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Index Medicus
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5. Full Text Translation regulator ballet in meiotic spindle
by Cormier, Patrick
Cell cycle (Georgetown, Tex.), ISSN 1538-4101, 04/2017, Volume 16, Issue 8, pp. 733 - 734
CDK1 | mTOR | 4E-BP1 | meiotic and mitotic spindle | mammalian oocyte | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Index Medicus | Life Sciences | Cellular Biology
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6. Full Text Oocyte meiotic spindle morphology is a predictive marker of blastocyst ploidy—a prospective cohort study
by Tilia, Liza and Chapman, Michael and Kilani, Suha and Cooke, Simon and Venetis, Christos
Fertility and sterility, ISSN 0015-0282, 01/2020, Volume 113, Issue 1, pp. 105 - 113.e1
blastocyst | Oocyte | meiotic spindle morphology | euploidy | Life Sciences & Biomedicine | Obstetrics & Gynecology | Reproductive Biology | Science & Technology | Index Medicus
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7. Full Text Alterations in oocyte mitochondrial number and function are related to spindle defects and occur with maternal aging in mice and humans
by Pasquariello, Rolando and Ermisch, Alison F and Silva, Elena and McCormick, Sue and Logsdon, Deirdre and Barfield, Jennifer P and Schoolcraft, William B and Krisher, Rebecca L
Biology of reproduction, ISSN 0006-3363, 04/2019, Volume 100, Issue 4, pp. 971 - 981
Aging | Oxidative stress | Mitochondria | Meiotic spindle | Oocyte | Life Sciences & Biomedicine | Reproductive Biology | Science & Technology | Antioxidants | Cysteine | Mitochondrial DNA | Ligases | Chromosomes | Analysis | Reproductive health | Eggs | Index Medicus
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8. Full Text Asymmetric Tyrosination of Spindle Microtubules Facilitates Selfish Inheritance
by Laloraya, Shikha
Trends in cell biology, ISSN 0962-8924, 06/2018, Volume 28, Issue 6, pp. 417 - 419
centromere | spindle asymmetry | selfish genetic element | meiotic drive | microtubule tyrosination | CENP-A | TTL | Cdc42 | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Female | Chromosome Segregation | Meiosis | Centromere | Humans | Microtubules | Proteins | Cell growth | Asymmetry | Biological evolution | Meiotic drive | Cell division | Genetics | Heredity | Chromosomes | Index Medicus
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9. Full Text Meeting the meiotic challenge: Specializations in mammalian oocyte spindle formation
by Severance, Ashley L and Latham, Keith E
Molecular reproduction and development, ISSN 1040-452X, 03/2018, Volume 85, Issue 3, pp. 178 - 187
aneuploidy | EIF4EBP1 | microtubule nucleation | oocyte meiotic spindle | meiosis | chromosome segregation | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Developmental Biology | Reproductive Biology | Science & Technology | Cell Biology | Phosphorylation | Chromatin | Polo-like kinase 1 | Centrosomes | Protein biosynthesis | Meiosis | Inactivation | Oocytes | Embryonic growth stage | Oogenesis | Specialization | Embryogenesis | Protein synthesis | Actin | Fertility | Spindles | Index Medicus
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10. Full Text Spindle tubulin and MTOC asymmetries may explain meiotic drive in oocytes
by Wu, Tianyu and Lane, Simon I. R and Morgan, Stephanie L and Jones, Keith T
Nature communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2952 - 11
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cytochalasin B - antagonists & inhibitors | Meiosis - physiology | Aurora Kinases - metabolism | Chromosome Segregation | Microinjections | Mice, Inbred C57BL | Microtubules - physiology | Nuclear Proteins - metabolism | Oocytes - cytology | Microtubule-Organizing Center - physiology | Animals | Oocytes - physiology | Centromere | Chromosomes - metabolism | Oocytes - drug effects | Female | Mice | Spindle Apparatus - physiology | Tubulin - physiology | Kinetochores - physiology | Kinetochores | Meiotic drive | Centromeres | Homology | Meiosis | Aurora kinase | Kinases | Oocytes | Genotype & phenotype | Tubulin | Asymmetry | Rodents | Chromosomes | Index Medicus
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