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Clinical & Experimental Immunology, ISSN 0009-9104, 06/2018, Volume 192, Issue 3, pp. 271 - 283
Head and neck squamous cell carcinoma (HNSCC) is a highly immunosuppressive malignancy. Exosomes in HNSCC patients' plasma are enriched in inhibitory cargo and... 
tumour‐derived exosomes (TEX) | disease progression | T cell‐derived exosomes | HNSCC | immune regulation | tumour-derived exosomes (TEX) | T cell-derived exosomes | HEAD | MELANOMA | REGULATORY T-CELLS | CANCER EXOSOMES | IMMUNOLOGY | EXPRESSION | Exosomes - metabolism | CD8-Positive T-Lymphocytes - cytology | OX40 Ligand - metabolism | CD4-Positive T-Lymphocytes - cytology | Humans | Middle Aged | Squamous Cell Carcinoma of Head and Neck - pathology | Cells, Cultured | CTLA-4 Antigen - metabolism | Male | Lewis X Antigen - metabolism | CD3 Complex - metabolism | B7-H1 Antigen - metabolism | Apoptosis - immunology | Flow Cytometry | Cyclooxygenase 2 - metabolism | Biomarkers, Tumor - metabolism | Adult | Female | Aged | COX-2 inhibitors | Squamous cell carcinoma | Analysis | Immunotherapy | Development and progression | T cells | Tumor proteins | Tumors | Enrichment | Plasma | Flow cytometry | CD8 antigen | Antibodies | Cytotoxicity | Lymphocytes T | Malignancy | Exosomes | Prostaglandin endoperoxide synthase | Proteins | Lymphocytes | Bioindicators | Neck | Head | Immunostimulation | Immunoregulation | CD3 antigen | T cell receptors | Disease control | Patients | Molecular chains | CD4 antigen | Immunosuppression | Ox40L protein | Tumor necrosis factor | Biomarkers | Head and neck cancer | Cancer | Apoptosis | Index Medicus | Original
Journal Article
Journal Article
by Hoshino, Ayuko and Costa-Silva, Bruno and Shen, Tang-Long and Rodrigues, Goncalo and Hashimoto, Ayako and Tesic Mark, Milica and Molina, Henrik and Kohsaka, Shinji and Di Giannatale, Angela and Ceder, Sophia and Singh, Swarnima and Williams, Caitlin and Soplop, Nadine and Uryu, Kunihiro and Pharmer, Lindsay and King, Tari and Bojmar, Linda and Davies, Alexander E and Ararso, Yonathan and Zhang, Tuo and Zhang, Haiying and Hernandez, Jonathan and Weiss, Joshua M and Dumont-Cole, Vanessa D and Kramer, Kimberly and Wexler, Leonard H and Narendran, Aru and Schwartz, Gary K and Healey, John H and Sandstrom, Per and Jørgen Labori, Knut and Kure, Elin H and Grandgenett, Paul M and Hollingsworth, Michael A and De Sousa, Maria and Kaur, Sukhwinder and Jain, Maneesh and Mallya, Kavita and Batra, Surinder K and Jarnagin, William R and Brady, Mary S and Fodstad, Oystein and Muller, Volkmar and Pantel, Klaus and Minn, Andy J and Bissell, Mina J and Garcia, Benjamin A and Kang, Yibin and Rajasekhar, Vinagolu K and Ghajar, Cyrus M and Matei, Irina and Peinado, Hector and Bromberg, Jacqueline and Lyden, David and Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States) and Weill Cornell Medicine, New York, NY (United States) and Memorial Sloan Kettering Cancer Center, New York, NY (United States) and Medicinska fakulteten and Region Östergötland and Kirurgiska kliniken US and Linköpings universitet and Institutionen för klinisk och experimentell medicin and Avdelningen för kliniska vetenskaper and Centrum för kirurgi, ortopedi och cancervård
Nature, ISSN 0028-0836, 11/2015, Volume 527, Issue 7578, pp. 329 - 335
Ever since Stephen Paget's 1889 hypothesis, metastatic organotropism has remained one of cancer's greatest mysteries. Here we demonstrate that exosomes from... 
CELLS | BONE METASTASES | VESICLES | BREAST-CANCER METASTASIS | MULTIDISCIPLINARY SCIENCES | IN-VIVO | GROWTH | NICHE | MICROVESICLES | PROTEINS | PROTEOMICS | Exosomes - metabolism | Tropism | Phosphorylation | Epithelial Cells - metabolism | Receptors, Vitronectin - antagonists & inhibitors | Humans | Lung - cytology | Integrin beta4 - metabolism | Integrins - metabolism | Brain - metabolism | Integrin alpha6beta1 - metabolism | S100 Proteins - genetics | Neoplasm Metastasis - prevention & control | Female | Kupffer Cells - metabolism | Lung - metabolism | Receptors, Vitronectin - metabolism | Epithelial Cells - cytology | Integrin alpha6beta4 - metabolism | Fibroblasts - metabolism | Biomarkers - metabolism | Brain - cytology | Kupffer Cells - cytology | Endothelial Cells - metabolism | Liver - metabolism | Mice, Inbred C57BL | Integrin alpha6beta4 - antagonists & inhibitors | Organ Specificity | Animals | Endothelial Cells - cytology | Neoplasm Metastasis - pathology | Cell Line, Tumor | Integrin beta Chains - metabolism | Fibroblasts - cytology | Liver - cytology | Mice | Genes, src | Integrins - antagonists & inhibitors | Complications and side effects | Development and progression | Cell organelles | Metastasis | Health aspects | Integrins | Tumors | Studies | Microscopy | Liver | Melanoma | Fibroblasts | Breast cancer | Chemokines | Index Medicus | mechanisms of disease | cancer microenvironment | BASIC BIOLOGICAL SCIENCES | metastasis | 60 APPLIED LIFE SCIENCES | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
Journal Article
Journal Article
Magnetic Resonance in Medicine, ISSN 0740-3194, 07/2015, Volume 74, Issue 1, pp. 266 - 271
PurposeExosomes are cell derived extracellular nanovesicles that relay molecular signals pertinent to both normal physiologic and disease processes. The... 
melanoma | nanomedicine | magnetic resonance imaging | exosome | lymph node | superparamagnetic iron oxide | STEM-CELLS | ELECTROPORATION | VESICLES | TUMOR EXOSOMES | DELIVERY | MAGNETOELECTROPORATION | TRACKING | SIRNA | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | TOOLS | Iron compounds | Magnetic resonance imaging | Ferric oxide | Melanoma
Journal Article
Nature Medicine, ISSN 1078-8956, 06/2012, Volume 18, Issue 6, pp. 883 - 891
Journal Article
Cancer Letters, ISSN 0304-3835, 2016, Volume 376, Issue 2, pp. 318 - 327
Journal Article