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Experimental Dermatology, ISSN 0906-6705, 06/2018, Volume 27, Issue 6, pp. 647 - 655
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 02/2016, Volume 246, pp. 20 - 29
Betulinic acid, a pentacyclic triterpene, and its derivatives are promising compounds for cancer treatment in humans. Melanoma is not only a problem for humans... 
NVX-207 | Flow cytometry | Cytotoxicity | Equine melanoma cell lines | Betulinic acid derivatives | APOPTOSIS | ACTIVATION | CANCER CELL | TRITERPENOIDS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEATH | TUMORS | GROWTH | PHARMACOLOGY & PHARMACY | TOXICOLOGY | SP TRANSCRIPTION FACTORS | NF-KAPPA-B | PHOSPHATIDYLSERINE | Chemotherapy | Safety and security measures | Analysis | Melanoma | Cancer
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 09/2018, Volume 19, Issue 9, p. 2583
Journal Article
Journal Article
Journal Article
British Journal of Cancer, ISSN 0007-0920, 10/2012, Volume 107, Issue 9, pp. 1488 - 1497
BACKGROUND: Glioblastoma multiforme (GBM) cells are resistant to anticancer drugs. Cancer stem cells (CSCs) are a key mediator of chemoresistance. We have... 
copper | GBM stem-like cells | disulfiram | gemcitabine | NFkB | reactive oxygen species | DRUG | SIGNALING PATHWAYS | ALDEHYDE DEHYDROGENASE | QUANTITATIVE-ANALYSIS | INHIBITION | ONCOLOGY | HUMAN-MELANOMA CELLS | PROMOTES SURVIVAL | NF-KAPPA-B | NF kappa B | BRAIN | Glioblastoma - enzymology | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Neoplastic Stem Cells - drug effects | Aldehyde Dehydrogenase - antagonists & inhibitors | Humans | Brain Neoplasms - pathology | Deoxycytidine - pharmacology | NF-kappa B - metabolism | Brain Neoplasms - metabolism | MAP Kinase Kinase 4 - metabolism | Neoplastic Stem Cells - pathology | Glioblastoma - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Aldehyde Dehydrogenase - metabolism | Brain Neoplasms - enzymology | NF-kappa B - antagonists & inhibitors | Copper - pharmacology | Brain Neoplasms - drug therapy | Drug Synergism | MAP Kinase Signaling System - drug effects | Glioblastoma - pathology | Cell Line, Tumor | Glioblastoma - drug therapy | Disulfiram - pharmacology | Neoplastic Stem Cells - enzymology | Deoxycytidine - analogs & derivatives | Cytotoxicity, Immunologic | glioblastoma multiforme | Reactive oxygen species | Chemoresistance | Cytotoxicity | Aldehyde dehydrogenase | Western blotting | Chemotherapy | NF- Kappa B protein | Antitumor agents | Reporter gene | Blood-brain barrier | c-Jun amino-terminal kinase | Stem cells | Disulfiram | Copper | glioblastoma cells | Apoptosis | Cancer | Translational Therapeutics | NFκB
Journal Article
REVISTA BRASILEIRA DE ANESTESIOLOGIA, ISSN 0034-7094, 11/2016, Volume 66, Issue 6, pp. 594 - 602
Background: Local anesthetics (LAs) are generally considered as safe, but cytotoxicity has been reported for several local anesthetics used in humans, which is... 
Flow cytometry | APOPTOSIS | Aminoamide local anesthetics | Cytotoxicity | BUPIVACAINE | Ropivacaine | DEATH | INDUCTION | NEUROTOXICITY | IN-VITRO | PRILOCAINE | ANESTHESIOLOGY | Lidocaine | Melanoma cell lines | MELPHALAN
Journal Article
Journal of Biological Inorganic Chemistry, ISSN 0949-8257, 2019, Volume 24, Issue 2, p. 223
Extraordinary progress in medicinal inorganic chemistry in the past few years led to the rational design of novel platinum compounds, as well as nonplatinum... 
Drug uptake | Stemness | Organotin(IV) compound | SBA-15 | A375 melanoma cell line
Journal Article
Cellular and Molecular Biology, ISSN 0145-5680, 2018, Volume 64, Issue 11, pp. 41 - 43
Dimethyl sulphoxide (DMSO) is widely used as a solvent in biomedical research, regularly in concentrations up to 1%. Nevertheless, little is known about the... 
Melanoma cell line | Metabolic activity | MTT | Dimethyl sulphoxide | Morphology | IN-VITRO | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | Melanoma - metabolism | Cell Line, Tumor | Cell Survival - drug effects | Dimethyl Sulfoxide - pharmacology | Microscopy, Phase-Contrast | Humans
Journal Article
Journal of Biological Regulators and Homeostatic Agents, ISSN 0393-974X, 04/2011, Volume 25, Issue 2, pp. 239 - 247
Journal Article
Bioorganic and Medicinal Chemistry Letters, ISSN 0960-894X, 03/2010, Volume 20, Issue 5, pp. 1573 - 1577
Journal Article
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, ISSN 0949-8257, 03/2019, Volume 24, Issue 2, pp. 223 - 234
Extraordinary progress in medicinal inorganic chemistry in the past few years led to the rational design of novel platinum compounds, as well as nonplatinum... 
Drug uptake | Stemness | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTICANCER AGENT | NOTCH | NANOCARRIERS | Organotin(IV) compound | MESOPOROUS SILICA NANOPARTICLES | BETA-CATENIN | IDENTIFICATION | CANCER | CHEMISTRY, INORGANIC & NUCLEAR | CISPLATIN | SENESCENCE | GENERATION | SBA-15 | A375 melanoma cell line
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 10/2008, Volume 14, Issue 20, pp. 6496 - 6504
Purpose: Survivin, a member of the inhibitor of apoptosis protein family, is an attractive target for cancer therapy. We have now investigated the effect of... 
non-small cell lung cancer | survivin | apoptosis | YM155 | DNA repair | ANTI-APOPTOSIS GENE | PROTEIN | INHIBITION | HISTONE H2AX PHOSPHORYLATION | ONCOLOGY | THERAPEUTIC TARGET | HUMAN-MELANOMA CELLS | DOWN-REGULATION | IONIZING-RADIATION | RADIATION SENSITIZATION | STRAND BREAKS | Carcinoma, Non-Small-Cell Lung - radiotherapy | Gamma Rays | Lung Neoplasms - drug therapy | Apoptosis - drug effects | Apoptosis - radiation effects | Microtubule-Associated Proteins - metabolism | Humans | Caspase 3 - metabolism | DNA Repair - radiation effects | Lung Neoplasms - radiotherapy | Immunoblotting | Lung Neoplasms - pathology | Neoplasm Proteins - antagonists & inhibitors | Neoplasm Proteins - metabolism | Radiation-Sensitizing Agents - therapeutic use | Female | Imidazoles - therapeutic use | Tumor Cells, Cultured | Histones - antagonists & inhibitors | Carcinoma, Non-Small-Cell Lung - pathology | Tumor Stem Cell Assay | Inhibitor of Apoptosis Proteins | Naphthoquinones - therapeutic use | Survival Rate | Combined Modality Therapy | Microtubule-Associated Proteins - antagonists & inhibitors | Survivin | Radiation Tolerance - drug effects | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Fluorescent Antibody Technique | Mice | Mice, Inbred BALB C | Carcinoma, Non-Small-Cell Lung - drug therapy | Histones - metabolism
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 2011, Volume 49, Issue 4, pp. 871 - 878
Honey is reported to contain various compounds such as phenols, vitamins and antioxidants. The present study investigates the anticancer potential of honey... 
Cytotoxicity | Lactate dehydrogenase | Annexin V | Tualang honey | Cancer cell lines | Apoptosis | DRUG | ASSAY | FOOD SCIENCE & TECHNOLOGY | CYCLE ARREST | PROLIFERATION | MECHANISMS | TOXICOLOGY | MELANOMA-CELLS | Honey | Membrane Potentials | Breast Neoplasms - pathology | Humans | Fluorescent Antibody Technique | Cell Line, Tumor | Female | Uterine Cervical Neoplasms - pathology
Journal Article