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PLoS ONE, ISSN 1932-6203, 03/2015, Volume 10, Issue 3, p. e0121788
Journal Article
Journal Article
F1000Research, ISSN 2046-1402, 2016, Volume 5, p. 368
Major histocompatibility complex (MHC) class II molecules present exogenously derived antigen peptides to CD4 T cells, driving activation of naïve T cells and... 
Autoimmunity | Leukocyte Signaling & Gene Expression | Cell Signaling & Trafficking Structures | Antigen Processing & Recognition | Membranes & Sorting | Cell Signaling | Control of Gene Expression | Genetics of the Immune System | Membrane Proteins & Energy Transduction
Journal Article
Frontiers in immunology, ISSN 1664-3224, 2017, Volume 8, p. 478
The initial infection and transmission of HIV-1 requires C-C chemokine receptor type 5 (CCR5). Here, we report that the membrane-proximal region (MPR, aa... 
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 04/2017, Volume 8
Journal Article
Vaccine, ISSN 0264-410X, 2017, Volume 35, Issue 20, pp. 2736 - 2744
Highlights • Secreted forms of HIV-1 gp41 ectodomain can be produced using mammalian cells. • Point mutations in gp41 MPER can increase secretion from... 
Allergy and Immunology | HIV-1 | DNA vaccine | Membrane-proximal external region | gp41 | Broadly neutralizing antibodies | MEDICINE, RESEARCH & EXPERIMENTAL | IMMUNE-RESPONSE | NEUTRALIZING ANTIBODIES | POTENT NEUTRALIZATION | HUMAN MONOCLONAL-ANTIBODY | BROAD | IMMUNOLOGY | VIRUS TYPE-1 ENVELOPE | EPITOPE | STRUCTURAL BASIS | PROTEINS | AGGREGATION | HIV Antibodies - blood | Vaccines, DNA - genetics | HIV Envelope Protein gp41 - genetics | Human Development | HIV Envelope Protein gp41 - immunology | Humans | Vaccines, Synthetic - genetics | AIDS Vaccines - immunology | Vaccines, DNA - immunology | Vaccines, Synthetic - immunology | HIV-1 - genetics | Vaccines, DNA - administration & dosage | HIV-1 - immunology | Animals | AIDS Vaccines - genetics | Female | Mice, Inbred BALB C | Vaccines, Synthetic - administration & dosage | AIDS Vaccines - administration & dosage | Vaccines | HIV (Viruses) | DNA | Cells | Protein binding | Proteins | Antigens | Gene mutations | Analysis | Cell culture | Medical research | Immunoglobulins | Glycoprotein gp41 | Peptides | Secretion | Cloning | Antibodies | Envelope protein | Viruses | DNA vaccines | Hydrophobicity | C-Terminus | Mutants | Mammalian cells | Conserved sequence | Clonal deletion | Immunogenicity | Human immunodeficiency virus--HIV | Mutation | Deoxyribonucleic acid--DNA
Journal Article
Current Opinion in HIV and AIDS, ISSN 1746-630X, 05/2017, Volume 12, Issue 3, pp. 250 - 256
PURPOSE OF REVIEWWe summarize the latest research on the progress to understand the neutralizing epitopes present within the membrane proximal external region... 
ECTODOMAIN REGION | 2F5 | INFECTIOUS DISEASES | FUSION | 10E8 | Gp41 | HIV-1 GP41 | 4E10 | TRANSMEMBRANE DOMAIN | IMMUNOLOGY | EPITOPE | STRUCTURAL BASIS | ENVELOPE | IMMUNODEFICIENCY-VIRUS TYPE-1 | membrane proximal external region | MONOCLONAL-ANTIBODIES | CRYO-EM STRUCTURE | Life Sciences | Biomolecules | Biochemistry, Molecular Biology
Journal Article
Vaccine, ISSN 0264-410X, 2013, Volume 31, Issue 46, pp. 5422 - 5429
Highlights • Chimeric BPV VLP vaccines were constructed to present HIV-1 MPER epitopes. • The induction of systemic and mucosal antibody responses was assessed... 
Allergy and Immunology | HIV-1 | Membrane-proximal external region | Vaccine | Mucosal | Neutralizing antibody | Bovine papillomavirus-like particle | MEDICINE, RESEARCH & EXPERIMENTAL | L1 PROTEIN | HUMAN MONOCLONAL-ANTIBODY | INDUCTION | IMMUNOLOGY | ORAL IMMUNIZATION | BROADLY NEUTRALIZING ANTIBODIES | CELLULAR IMMUNE-RESPONSES | IMMUNODEFICIENCY-VIRUS TYPE-1 | SURFACE-ANTIGEN | INFECTION | HIV Antibodies - blood | HIV Envelope Protein gp41 - genetics | Immunoglobulin G - blood | HIV Envelope Protein gp41 - immunology | AIDS Vaccines - immunology | Immunity, Mucosal | Vaccines, Synthetic - immunology | Papillomaviridae - genetics | Drug Carriers | Epitopes - immunology | Immunoglobulin A, Secretory - blood | Vaccines, Virus-Like Particle - genetics | Cattle | Female | HIV Antibodies - analysis | Administration, Oral | Vaccines, Synthetic - genetics | Immunoglobulin A, Secretory - analysis | Epitopes - genetics | HIV-1 - genetics | HIV-1 - immunology | Vaccines, Virus-Like Particle - administration & dosage | Animals | AIDS Vaccines - genetics | Vaccines, Virus-Like Particle - immunology | Mice | Mice, Inbred BALB C | Vaccines, Synthetic - administration & dosage | AIDS Vaccines - administration & dosage | HIV (Viruses) | Immunoglobulin G | Antigenic determinants | Mutation | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Rodents | neutralizing antibody | membrane-proximal external region | vaccine | bovine papillomavirus-like particle | mucosal
Journal Article