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2015, Chapman & Hall/CRC interdisciplinary statics series, ISBN 1466573171, xiv, 210
Presents the Terminology and Methods of Mendelian Randomization for Epidemiological Studies Mendelian randomization uses genetic instrumental variables to make inferences about causal effects based on observational data... 
Statistics as Topic | Statistical methods | Genetics, Medical | Genetic epidemiology | Epidemiologic Methods | Medical genetics | Medicine: General Issues | Statistical Theory & Methods | Statistics for the Biological Sciences | Epidemiology
Book
International journal of epidemiology, ISSN 1464-3685, 2018, Volume 47, Issue 4, pp. 1279 - 1288
Journal Article
International journal of epidemiology, ISSN 1464-3685, 2013, Volume 42, Issue 5, pp. 1497 - 1501
In Mendelian randomization (MR) studies, where genetic variants are used as proxy measures for an exposure trait of interest, obtaining adequate statistical power is frequently a concern due to the small amount of variation... 
Instrumental variable | Mendelian randomization | Power | Non-centrality parameter | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | instrumental variable | non-centrality parameter | GENES | EPIDEMIOLOGY | Sample Size | Statistics as Topic | Causality | Humans | Mendelian Randomization Analysis | Methodology
Journal Article
by Voight, Benjamin F and Peloso, Gina M and Orho-Melander, Marju and Frikke-Schmidt, Ruth and Barbalic, Maja and Jensen, Majken K and Hindy, George and Hólm, Hilma and Ding, Eric L and Johnson, Toby and Schunkert, Heribert and Samani, Nilesh J and Clarke, Robert and Hopewell, Jemma C and Thompson, John F and Li, Mingyao and Thorleifsson, Gudmar and Newton-Cheh, Christopher and Musunuru, Kiran and Pirruccello, James P and Saleheen, Danish and Chen, Li and Stewart, Alexandre FR and Schillert, Arne and Thorsteinsdottir, Unnur and Thorgeirsson, Gudmundur and Anand, Sonia and Engert, James C and Morgan, Thomas and Spertus, John and Stoll, Monika and Berger, Klaus and Martinelli, Nicola and Girelli, Domenico and McKeown, Pascal P and Patterson, Christopher C and Epstein, Stephen E and Devaney, Joseph and Burnett, Mary-Susan and Mooser, Vincent and Ripatti, Samuli and Surakka, Ida and Nieminen, Markku S and Sinisalo, Juha and Lokki, Marja-Liisa and Perola, Markus and Havulinna, Aki and de Faire, Ulf and Gigante, Bruna and Ingelsson, Erik and Zeller, Tanja and Wild, Philipp and de Bakker, Paul I W and Klungel, Olaf H and Maitland-van der Zee, Anke-Hilse and Peters, Bas J M and de Boer, Anthonius and Grobbee, Diederick E and Kamphuisen, Pieter W and Deneer, Vera H M and Elbers, Clara C and Onland-Moret, N Charlotte and Hofker, Marten H and Wijmenga, Cisca and Verschuren, WM Monique and Boer, Jolanda MA and van der Schouw, Yvonne T and Rasheed, Asif and Frossard, Philippe and Demissie, Serkalem and Willer, Cristen and Do, Ron and Ordovas, Jose M and Abecasis, Gonçalo R and Boehnke, Michael and Mohlke, Karen L and Daly, Mark J and Guiducci, Candace and Burtt, Noël P and Surti, Aarti and Gonzalez, Elena and Purcell, Shaun and Gabriel, Stacey and Marrugat, Jaume and Peden, John and Erdmann, Jeanette and Diemert, Patrick and Willenborg, Christina and König, Inke R and Fischer, Marcus and Hengstenberg, Christian and Ziegler, Andreas and Buysschaert, Ian and Lambrechts, Diether and Van de Werf, Frans and Fox, Keith A and El Mokhtari, Nour Eddine and Rubin, Diana and Schrezenmeir, Jürgen and Schreiber, Stefan and ...
The Lancet (British edition), ISSN 0140-6736, 2012, Volume 380, Issue 9841, pp. 572 - 580
Journal Article
Stroke, ISSN 0039-2499, 03/2018, Volume 49, Issue 4, pp. 820 - 827
.... Our aim was to investigate the causal role of LDL cholesterol, high-density lipoprotein cholesterol, and triglycerides in ischemic stroke and its subtypes through Mendelian randomization (MR). METHODS... 
HDL | Stroke | LDL | Triglycerides | Single nucleotide | Cholesterol | Polymorphism | MULTICENTER | CAROTID ATHEROSCLEROSIS | cholesterol, LDL | RISK | PCSK9 | triglycerides | DENSITY-LIPOPROTEIN-CHOLESTEROL | stroke | CLINICAL NEUROLOGY | CEREBROVASCULAR-DISEASE | polymorphism, single nucleotide | cholesterol, HDL | PLEIOTROPIC GENETIC-VARIANTS | PERIPHERAL VASCULAR DISEASE | ASSOCIATION | INSIGHTS | Intracranial Embolism - genetics | Multivariate Analysis | Cerebral Small Vessel Diseases - genetics | Intracranial Embolism - blood | Humans | Brain Ischemia - genetics | Intracranial Arteriosclerosis - genetics | Cholesterol, HDL - genetics | Stroke - genetics | Stroke - blood | Cholesterol, LDL - genetics | Brain Ischemia - blood | Mendelian Randomization Analysis | Triglycerides - blood | Cerebral Small Vessel Diseases - blood | Cholesterol, HDL - blood | Cholesterol, LDL - blood | Polymorphism, Single Nucleotide | Triglycerides - genetics | Causality | Intracranial Arteriosclerosis - blood | Stroke (Disease) | Prevention | Care and treatment | Cholesterol, HDL | Analysis | Genetic aspects | Single nucleotide polymorphisms | Research | Health aspects | 10071 | Original Contributions | 10178 | 10034 | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Kardiologi | Clinical Medicine | Cardiac and Cardiovascular Systems
Journal Article
Human molecular genetics, ISSN 1460-2083, 2014, Volume 23, Issue R1, pp. R89 - R98
Journal Article
Circulation, ISSN 0009-7322, 06/2017, Volume 135, Issue 24, pp. 2373 - 2388
Journal Article
Journal Article
by Holmes, Michael V and Asselbergs, Folkert W and Palmer, Tom M and Drenos, Fotios and Lanktree, Matthew B and Nelson, Christopher P and Dale, Caroline E and Padmanabhan, Sandosh and Finan, Chris and Swerdlow, Daniel I and Tragante, Vinicius and van Iperen, Erik P.A and Sivapalaratnam, Suthesh and Shah, Sonia and Elbers, Clara C and Shah, Tina and Engmann, Jorgen and Giambartolomei, Claudia and White, Jon and Zabaneh, Delilah and Sofat, Reecha and McLachlan, Stela and Doevendans, Pieter A and Balmforth, Anthony J and Hall, Alistair S and North, Kari E and Almoguera, Berta and Hoogeveen, Ron C and Cushman, Mary and Fornage, Myriam and Patel, Sanjay R and Redline, Susan and Siscovick, David S and Tsai, Michael Y and Karczewski, Konrad J and Hofker, Marten H and Verschuren, W. Monique and Bots, Michiel L and van der Schouw, Yvonne T and Melander, Olle and Dominiczak, Anna F and Morris, Richard and Ben-Shlomo, Yoav and Price, Jackie and Kumari, Meena and Baumert, Jens and Peters, Annette and Thorand, Barbara and Koenig, Wolfgang and Gaunt, Tom R and Humphries, Steve E and Clarke, Robert and Watkins, Hugh and Farrall, Martin and Wilson, James G and Rich, Stephen S and de Bakker, Paul I.W and Lange, Leslie A and Davey Smith, George and Reiner, Alex P and Talmud, Philippa J and Kivimäki, Mika and Lawlor, Debbie A and Dudbridge, Frank and Samani, Nilesh J and Keating, Brendan J and Hingorani, Aroon D and Casas, Juan P and on behalf of the UCLEB consortium and UCLEB Consortium and UCLEB consortium
European heart journal, ISSN 1522-9645, 2015, Volume 36, Issue 9, pp. 539 - 550
Journal Article