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1. Full Text Meperidine-induced QTc-interval prolongation: Prevalence, risk factors, and correlation to plasma drug and metabolite concentrations
by Keller, Guillermo Alberto and Etchegoyen, María Cecilia Villa and Fernández, Nicolás and Olivera, Nancy Mónica and Quiroga, Patricia Noemí and Diez, Roberto Alejandro and Girolamo, Guillermo Di
International journal of clinical pharmacology and therapeutics, ISSN 0946-1965, 2017, Volume 55, Issue 3, pp. 275 - 285
Adverse drug reaction | Arrhythmia | Torsade des pointes | Qt-interval prolongation | Meperidine | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Prevalence | Prospective Studies | Humans | Middle Aged | Argentina - epidemiology | Long QT Syndrome - chemically induced | Male | Renal Insufficiency - epidemiology | Long QT Syndrome - physiopathology | Heart Rate - drug effects | Long QT Syndrome - diagnosis | Analgesics, Opioid - adverse effects | Biotransformation | Aged, 80 and over | Electrocardiography | Female | Meperidine - blood | Action Potentials - drug effects | Meperidine - adverse effects | Analgesics, Opioid - blood | Risk Assessment | Long QT Syndrome - epidemiology | Risk Factors | Heart Conduction System - drug effects | Heart Conduction System - physiopathology | Analgesics, Opioid - pharmacokinetics | Meperidine - pharmacokinetics | Aged | Longitudinal Studies | Meperidine - analogs & derivatives | Index Medicus
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2. Full Text Intravenous remifentanil patient-controlled analgesia versus intramuscular pethidine for pain relief in labour (RESPITE): an open-label, multicentre, randomised controlled trial
by Wilson, Matthew J A and MacArthur, Christine and Hewitt, Catherine A and Handley, Kelly and Gao, Fang and Beeson, Leanne and Daniels, Jane and RESPITE Trial Collaborative Group and RESPITE Trial Collaborative Grp
The Lancet (British edition), ISSN 0140-6736, 08/2018, Volume 392, Issue 10148, pp. 662 - 672
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Piperidines - administration & dosage | Analgesia, Patient-Controlled - methods | Labor Pain - drug therapy | Outcome Assessment (Health Care) | Humans | Meperidine - administration & dosage | Analgesics, Opioid - pharmacology | Analgesia, Epidural - statistics & numerical data | Injections, Intramuscular | Meperidine - pharmacology | Remifentanil | Pregnancy | Young Adult | Administration, Intravenous | Analgesia, Obstetrical - methods | Patient Satisfaction - statistics & numerical data | Adolescent | Adult | Female | United Kingdom - epidemiology | Analgesia, Obstetrical - adverse effects | Care and treatment | Pain | Pregnant women | Analysis | Health care industry | Meperidine | Drug delivery systems | Pain perception | Intravenous administration | Narcotics | Vagina | Gestation | Minority & ethnic groups | Evidence-based medicine | Morbidity | Childbirth & labor | Studies | Analgesia | Randomization | Motivation | Quality | Pain management | Opioids | Index Medicus | Abridged Index Medicus
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3. Full Text Simultaneous quantitation of meperidine, normeperidine, tramadol, propoxyphene and norpropoxyphene in human plasma using solid‐phase extraction and gas chromatography/mass spectrometry: Method validation and application to cardiovascular safety of therapeutic doses
by Fernández, Nicolás and Olivera, Nancy Mónica and Keller, Guillermo Alberto and Diez, Roberto Alberto and Di Girolamo, Guillermo and Quiroga, Patricia Noemí
Rapid communications in mass spectrometry, ISSN 0951-4198, 09/2017, Volume 31, Issue 18, pp. 1519 - 1533
Spectroscopy | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Technology | Biochemical Research Methods | Chemistry, Analytical | Science & Technology | Meperidine - isolation & purification | Gas Chromatography-Mass Spectrometry - methods | Meperidine - adverse effects | Tramadol - blood | Analgesics, Opioid - blood | Dextropropoxyphene - adverse effects | Humans | Tramadol - adverse effects | Analgesics, Opioid - isolation & purification | Tramadol - isolation & purification | Dextropropoxyphene - analogs & derivatives | Analgesics, Opioid - adverse effects | Solid Phase Extraction - methods | Heart - drug effects | Dextropropoxyphene - blood | Dextropropoxyphene - isolation & purification | Drug Monitoring | Meperidine - analogs & derivatives | Meperidine - blood | Propoxyphene | Mass spectrometry | Health aspects | Methods | Chromatography | Plasma | Elution | Narcotics | Forensic engineering | Correlation coefficients | Ions | Blood plasma | Gas chromatography | Analgesics | Metabolites | Ionization | Correlation analysis | Linearity | Extraction | Scientific imaging | Deuteration | Monitoring | Prolongation | Plasmas (physics) | Index Medicus
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4. Full Text Muscarinic acetylcholine receptor binding affinities of pethidine analogs
by Lee, Na-Ra and Zhang, Xuan and Darna, Mahesh and Dwoskin, Linda P and Zheng, Guangrong
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 11/2015, Volume 25, Issue 22, pp. 5032 - 5035
Drug abuse | [3H]NMS binding affinity | Pethidine | Muscarinic acetylcholine receptors | H]NMS binding affinity | Cricetulus | Humans | Receptor, Muscarinic M3 - metabolism | Receptor, Muscarinic M5 - metabolism | Structure-Activity Relationship | Meperidine - chemical synthesis | Animals | Female | Ligands | Meperidine - analogs & derivatives | Receptor, Muscarinic M1 - metabolism | CHO Cells | Meperidine - metabolism | Meperidine | Index Medicus | drug abuse | pethidine | muscarinic acetylcholine receptors
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5. Pharmacokinetics of meperidine (pethidine) in rabbit oral fluid: Correlation with plasma concentrations after controlled administration
by Cao, Jie and Li, Yu and Du, Yan and Wang, Yu-Jin and Wu, Bin and Jia, Juan and Wei, Zhi-Wen and Yun, Ke-Ming and Liang, Wu and Wang, Ying-Yuan and Sun, Jun-Hong
Pharmazie, ISSN 0031-7144, 2018, Volume 73, Issue 6, pp. 324 - 328
Physical Sciences | Chemistry | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Chemistry, Multidisciplinary | Science & Technology | Rabbits | Gas Chromatography-Mass Spectrometry - methods | Reproducibility of Results | Meperidine - administration & dosage | Male | Drug Monitoring - methods | Analgesics, Opioid - analysis | Administration, Intravenous | Animals | Time Factors | Analgesics, Opioid - administration & dosage | Meperidine - analysis | Analgesics, Opioid - pharmacokinetics | Meperidine - pharmacokinetics | Meperidine - analogs & derivatives
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6. Full Text Comparison of efficacy of meperidine and fentanyl in terms of pain management and quality of life in patients with cervical cancer receiving intracavitary brachytherapy: a double-blind, randomized controlled trial
by Thanthong, Saengrawee and Rojthamarat, Sirikorn and Worasawate, Wipra and Vichitvejpaisal, Phongthara and Nantajit, Danupon and Ieumwananontachai, Nantakarn
Supportive care in cancer, ISSN 0941-4355, 08/2017, Volume 25, Issue 8, pp. 2531 - 2537
Fentanyl | Brachytherapy | Meperidine | Pain management | Quality of life | Health Care Sciences & Services | Oncology | Rehabilitation | Life Sciences & Biomedicine | Science & Technology | Fentanyl - administration & dosage | Meperidine - therapeutic use | Double-Blind Method | Fentanyl - therapeutic use | Humans | Middle Aged | Brachytherapy - methods | Meperidine - administration & dosage | Pain Management - methods | Analgesics, Opioid - pharmacology | Analgesics, Opioid - therapeutic use | Male | Uterine Cervical Neoplasms - drug therapy | Uterine Cervical Neoplasms - pathology | Fentanyl - pharmacology | Meperidine - pharmacology | Uterine Cervical Neoplasms - psychology | Young Adult | Analgesics, Opioid - administration & dosage | Aged, 80 and over | Adult | Female | Aged | Quality of Life - psychology | Medical personnel | Cancer patients | Care and treatment | Pain | Radioisotope brachytherapy | Clinical trials | Comparative analysis | Cervical cancer | Benzodiazepines | Comparative studies | Radiation therapy | Evidence-based medicine | Index Medicus
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7. Full Text Impact of cytochrome P450 variation on meperidine N-demethylation to the neurotoxic metabolite normeperidine
by Murray, Jessica L and Mercer, Susan L and Jackson, Klarissa D
Xenobiotica, ISSN 0049-8254, 02/2020, Volume 50, Issue 2, pp. 132 - 145
neurotoxic metabolite | reaction phenotyping | meperidine | genetic polymorphism | Cytochrome P450 | Pharmacology & Pharmacy | Toxicology | Life Sciences & Biomedicine | Science & Technology | Demethylation | Cholinesterase Inhibitors - metabolism | Humans | Cytochrome P-450 Enzyme System - metabolism | Mephenytoin | Cytochrome P-450 CYP2C19 - metabolism | Meperidine - analogs & derivatives | Meperidine - metabolism | Index Medicus | cytochrome P450
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8. Full Text Obstetric analgesia: a comparison of patient-controlled meperidine, remifentanil, and fentanyl in labour
by Douma, M.R and Verwey, R.A and Kam-Endtz, C.E and van der Linden, P.D and Stienstra, R
British journal of anaesthesia : BJA, ISSN 0007-0912, 02/2010, Volume 104, Issue 2, pp. 209 - 215
analgesia, obstetric | analgesics opioid, fentanyl | analgesia, patient-controlled | analgesics opioid, meperidine | analgesics opioid, remifentanil | Analgesics opioid, remifentanil | Analgesia, patient-controlled | Analgesics opioid, meperidine | Analgesics opioid, fentanyl | Analgesia, obstetric | Life Sciences & Biomedicine | Anesthesiology | Science & Technology | Biological and medical sciences | Anesthesia | Medical sciences | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy | Consciousness - drug effects | Fentanyl - administration & dosage | Meperidine - adverse effects | Piperidines - administration & dosage | Fentanyl - adverse effects | Analgesia, Patient-Controlled - methods | Double-Blind Method | Humans | Meperidine - administration & dosage | Oxygen - blood | Patient Satisfaction | Pregnancy | Pain Measurement - methods | Analgesics, Opioid - adverse effects | Analgesia, Obstetrical - methods | Analgesics, Opioid - administration & dosage | Piperidines - adverse effects | Adult | Analgesia, Patient-Controlled - adverse effects | Female | Analgesia, Obstetrical - adverse effects | Pregnancy Outcome | Pruritus - chemically induced | Index Medicus
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9. Full Text The effects of novel α 2 -adrenoreceptor agonist dexmedetomidine on shivering in patients underwent caesarean section
by Yu, Gaofeng and Yu, Gaofeng and Jin, Shangyi and Chen, Jinghui and Yao, Weifeng and Yao, Weifeng and Song, Xingrong
Bioscience reports, ISSN 0144-8463, 02/2019, Volume 39, Issue 2
caesarean delivery | dexmedetomidine | combined spinal-epidural anesthesia | shivering | meperidine | Anesthesia, Epidural - adverse effects | Dexmedetomidine - administration & dosage | Dexmedetomidine - therapeutic use | Meperidine - therapeutic use | Double-Blind Method | Humans | Meperidine - administration & dosage | Treatment Outcome | Pregnancy | Cesarean Section | Administration, Intravenous | Anesthesia, Spinal - adverse effects | Adrenergic alpha-2 Receptor Agonists - therapeutic use | Postoperative Care | Shivering - drug effects | Adult | Body Temperature Regulation - drug effects | Female
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10. Full Text Taking the alternative route: Women's experience of intranasal fentanyl, subcutaneous fentanyl or intramuscular pethidine for labour analgesia
by Fleet, Julie-Anne and Jones, Meril and Belan, Ingrid
Midwifery, ISSN 0266-6138, 10/2017, Volume 53, pp. 15 - 19
Fentanyl | Opioid | Analgesia | Labour | Pain relief | Pethidine | Life Sciences & Biomedicine | Nursing | Science & Technology | Fentanyl - administration & dosage | Analgesics - therapeutic use | Meperidine - therapeutic use | Labor Pain - drug therapy | Fentanyl - therapeutic use | Humans | Meperidine - administration & dosage | Pain Management - methods | Analgesics - administration & dosage | Fentanyl - pharmacology | Injections, Subcutaneous - standards | Meperidine - pharmacology | Patient Satisfaction | South Australia | Pregnancy | Administration, Intranasal - standards | Adult | Female | Qualitative Research | Injections, Intramuscular - standards | Drug-Related Side Effects and Adverse Reactions - psychology | Meperidine | Women | Care and treatment | Pain | Analysis | Physiological aspects | Health aspects | Midwives | Drug delivery systems | Narcotics | Nasal sprays | Sense of control | Childbirth & labor | Drug administration | Side effects | Analgesics | Postpartum women | Womens health | Pain management | Telephone surveys | Emotional responses | Autonomy | Patient satisfaction | Invasive | Content analysis | Quantitative analysis
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11. Full Text A comparison between remifentanil and meperidine for labor analgesia: A systematic review
by Leong, Wan Ling and Sng, Ban Leong and Sia, Alex Tiong Heng
Anesthesia and analgesia, ISSN 0003-2999, 2011, Volume 113, Issue 4, pp. 818 - 825
Life Sciences & Biomedicine | Anesthesiology | Science & Technology | Biological and medical sciences | Anesthesia | Medical sciences | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy | Meperidine - adverse effects | Meperidine - therapeutic use | Labor Pain - drug therapy | Humans | Analgesics, Opioid - therapeutic use | Treatment Outcome | Patient Selection | Pregnancy | Analgesics, Opioid - adverse effects | Analgesia, Obstetrical - methods | Piperidines - therapeutic use | Piperidines - adverse effects | Analgesics, Opioid - pharmacokinetics | Female | Meperidine - pharmacokinetics | Piperidines - pharmacokinetics | Odds Ratio | Pain Measurement | Index Medicus | Abridged Index Medicus
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12. Full Text Assisted sonocatalytic degradation of pethidine hydrochloride with some inorganic oxidants caused by CdS-coated ZrO.sub.2 composite
by Huang, Yingying and Zhang, Hongbo and Wei, Chunsheng and Li, Guanshu and Wu, Qiong and Wang, Jun and Song, Youtao
Separation and purification technology, ISSN 1383-5866, 01/2017, Volume 172, p. 202
Meperidine | Precipitation (Meteorology) | X-ray spectroscopy
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13. Full Text Sa1760 Risk Factors of Vital Sign Fluctuation During Screening Colonoscopy With Conscious Sedation Using Midazolam, Meperidine, or Combination of Both
by Bannno, Shigeo and Kato, Motohiko and Sakaguchi, Emi and Takada, Yoshiaki and Abe, Keiichiro and Hirata, Tetsu and Wada, Michiko and Takatori, Yusaku and Kinoshita, Satoshi and Takabayashi, Kaoru and Kikuchi, Miho and Kikuchi, Masahiro and Fujiyama, Youichi and Uraoka, Toshio
Gastrointestinal endoscopy, ISSN 0016-5107, 2016, Volume 83, Issue 5, pp. AB289 - AB290
Gastroenterology and Hepatology | Colonoscopy | Meperidine | Midazolam
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