Oncotarget, ISSN 1949-2553, 06/2018, Volume 9, Issue 48, pp. 28910 - 28920
Journal Article
FRONTIERS IN MICROBIOLOGY, ISSN 1664-302X, 10/2018, Volume 9
It is known that viruses can active the phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway in host cells to support cell survival and viral...
MOLECULAR CHARACTERIZATION | TRANSFORMATION | protein interaction | virus replication | KINASE | apoptosis | MICROBIOLOGY | ONCOPROTEIN MEQ | Marek's disease virus | NS1 PROTEIN | SIGNALING PATHWAY | INFECTION | PI3K/Akt signaling pathway | FIELD STRAIN | BINDING
MOLECULAR CHARACTERIZATION | TRANSFORMATION | protein interaction | virus replication | KINASE | apoptosis | MICROBIOLOGY | ONCOPROTEIN MEQ | Marek's disease virus | NS1 PROTEIN | SIGNALING PATHWAY | INFECTION | PI3K/Akt signaling pathway | FIELD STRAIN | BINDING
Journal Article
Journal of Virological Methods, ISSN 0166-0934, 10/2016, Volume 236, pp. 271 - 280
Marek’s disease (MD), is an economically important virus disease of poultry throughout the world. In this study, we for the first time reports development of a...
Dot-ELISA | Meq oncoprotein | Marek’s disease virus | Diagnosis | Poultry | Lymphoma
Dot-ELISA | Meq oncoprotein | Marek’s disease virus | Diagnosis | Poultry | Lymphoma
Journal Article
Journal of Virological Methods, ISSN 0166-0934, 10/2016, Volume 236, pp. 271 - 280
Marek's disease (MD), is an economically important virus disease of poultry throughout the world. In this study, we for the first time reports development of a...
Dot-ELISA | Meq oncoprotein | Marek's disease virus | Diagnosis | Poultry | Lymphoma | TRANSFORMATION | ANTIBODIES | ENCODES | ONCOPROTEIN | VIRUS MDV | BIOCHEMICAL RESEARCH METHODS | CHICKENS | NUCLEAR-LOCALIZATION | VIROLOGY | GENE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | INFECTION | LYMPHOCYTES | Enzyme-Linked Immunosorbent Assay - methods | Animals | Costs and Cost Analysis | Lymphoma - etiology | Time Factors | Marek Disease - diagnosis | Sensitivity and Specificity | Poultry Diseases - diagnosis | Marek Disease - complications | Oncogene Proteins, Viral - analysis | Poultry industry | Lymphomas | Research institutes | Enzyme-linked immunosorbent assay | Virus diseases | Antigens | Enzymes | Phosphatases | Development and progression
Dot-ELISA | Meq oncoprotein | Marek's disease virus | Diagnosis | Poultry | Lymphoma | TRANSFORMATION | ANTIBODIES | ENCODES | ONCOPROTEIN | VIRUS MDV | BIOCHEMICAL RESEARCH METHODS | CHICKENS | NUCLEAR-LOCALIZATION | VIROLOGY | GENE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | INFECTION | LYMPHOCYTES | Enzyme-Linked Immunosorbent Assay - methods | Animals | Costs and Cost Analysis | Lymphoma - etiology | Time Factors | Marek Disease - diagnosis | Sensitivity and Specificity | Poultry Diseases - diagnosis | Marek Disease - complications | Oncogene Proteins, Viral - analysis | Poultry industry | Lymphomas | Research institutes | Enzyme-linked immunosorbent assay | Virus diseases | Antigens | Enzymes | Phosphatases | Development and progression
Journal Article
Journal of Virology, ISSN 0022-538X, 09/2000, Volume 74, Issue 17, pp. 7980 - 7988
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley...
ICP4 HOMOLOG GENE | OPEN READING FRAMES | VIROLOGY | TRANSFORMED LYMPHOBLASTOID-CELLS | INVERTED REPEAT SEQUENCES | AMINO-ACID-SEQUENCES | SERIAL INVITRO PASSAGE | SHORT UNIQUE REGION | LATENCY-ASSOCIATED TRANSCRIPTS | HERPES-SIMPLEX VIRUS | SMOOTH-MUSCLE CELLS | Amino Acid Sequence | Cell Line | Genome, Viral | Molecular Sequence Data | DNA, Viral - analysis | Herpesvirus 2, Gallid - isolation & purification | Sequence Analysis, DNA | Marek Disease - virology | Herpesvirus 2, Gallid - pathogenicity | Sequence Alignment | Animals | Herpesvirus 2, Gallid - genetics | Virulence - genetics | Chickens | MD5 protein | pp38 protein | ICP4 protein | MDV093 protein | MDV097 protein | MEQ protein | pp24 protein | Pathogenesis and Immunity
ICP4 HOMOLOG GENE | OPEN READING FRAMES | VIROLOGY | TRANSFORMED LYMPHOBLASTOID-CELLS | INVERTED REPEAT SEQUENCES | AMINO-ACID-SEQUENCES | SERIAL INVITRO PASSAGE | SHORT UNIQUE REGION | LATENCY-ASSOCIATED TRANSCRIPTS | HERPES-SIMPLEX VIRUS | SMOOTH-MUSCLE CELLS | Amino Acid Sequence | Cell Line | Genome, Viral | Molecular Sequence Data | DNA, Viral - analysis | Herpesvirus 2, Gallid - isolation & purification | Sequence Analysis, DNA | Marek Disease - virology | Herpesvirus 2, Gallid - pathogenicity | Sequence Alignment | Animals | Herpesvirus 2, Gallid - genetics | Virulence - genetics | Chickens | MD5 protein | pp38 protein | ICP4 protein | MDV093 protein | MDV097 protein | MEQ protein | pp24 protein | Pathogenesis and Immunity
Journal Article
6.
Full Text
Expression of Marek's Disease Virus Oncoprotein Meq During Infection in the Natural Host
Virology, ISSN 0042-6822, 2017, Volume 503, pp. 103 - 113
Abstract Gallid herpesvirus 2 (Marek's disease virus, MDV) causes lymphoproliferative Marek's disease (MD), and is unique among alphaherpesviruses as the viral...
Infectious Disease | bacterial artificial chromosome | pathogenesis | oncogenesis | Gallid herpesvirus 2 | Meq | flow cytometry | latent infection | Marek's disease | TRANSFORMATION | ENCODES | PROTEIN | SUBSETS | VIROLOGY | GENE | PATHWAY | CHICKEN | RESISTANCE | LATENCY | MDV | Recombinant Proteins - metabolism | Cell Line | Chickens - virology | Herpesvirus 2, Gallid - immunology | Green Fluorescent Proteins - genetics | Recombinant Proteins - genetics | Poultry Diseases - virology | Chick Embryo | Oncogene Proteins, Viral - biosynthesis | Marek Disease - virology | CD4-Positive T-Lymphocytes - immunology | Herpesvirus 2, Gallid - pathogenicity | Animals | Herpesvirus 2, Gallid - genetics | Polymerase Chain Reaction | Cell Transformation, Viral - genetics | Oncogene Proteins, Viral - genetics | Health aspects | Genomics | Lymphomas
Infectious Disease | bacterial artificial chromosome | pathogenesis | oncogenesis | Gallid herpesvirus 2 | Meq | flow cytometry | latent infection | Marek's disease | TRANSFORMATION | ENCODES | PROTEIN | SUBSETS | VIROLOGY | GENE | PATHWAY | CHICKEN | RESISTANCE | LATENCY | MDV | Recombinant Proteins - metabolism | Cell Line | Chickens - virology | Herpesvirus 2, Gallid - immunology | Green Fluorescent Proteins - genetics | Recombinant Proteins - genetics | Poultry Diseases - virology | Chick Embryo | Oncogene Proteins, Viral - biosynthesis | Marek Disease - virology | CD4-Positive T-Lymphocytes - immunology | Herpesvirus 2, Gallid - pathogenicity | Animals | Herpesvirus 2, Gallid - genetics | Polymerase Chain Reaction | Cell Transformation, Viral - genetics | Oncogene Proteins, Viral - genetics | Health aspects | Genomics | Lymphomas
Journal Article
JOURNAL OF GENERAL VIROLOGY, ISSN 0022-1317, 12/2018, Volume 99, Issue 12, pp. 1705 - 1716
Codon pair bias deoptimization (CPBD) has been successfully used to attenuate several RNA viruses. CPBD involves recoding a viral protein-coding sequence to...
CELLS | attenuation | codon pair bias deoptimization | PROTEIN | GENOME | DELETION | synthetic attenuated virus engineering | Marek's disease virus | VIROLOGY | GENE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | herpesvirus | meq | OPTIMIZATION | INFLUENZA-VIRUS | large-scale recoding | EXPRESSION | VACCINES | Recombinant Proteins - metabolism | Cell Line | Virulence | Recombinant Proteins - genetics | Animals | Codon | Virus Replication | Herpesvirus 1, Meleagrid - growth & development | Chickens | Epithelial Cells - virology | Oncogene Proteins, Viral - genetics | Virus Cultivation | Herpesvirus 1, Meleagrid - genetics | Oncogene Proteins, Viral - metabolism
CELLS | attenuation | codon pair bias deoptimization | PROTEIN | GENOME | DELETION | synthetic attenuated virus engineering | Marek's disease virus | VIROLOGY | GENE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | herpesvirus | meq | OPTIMIZATION | INFLUENZA-VIRUS | large-scale recoding | EXPRESSION | VACCINES | Recombinant Proteins - metabolism | Cell Line | Virulence | Recombinant Proteins - genetics | Animals | Codon | Virus Replication | Herpesvirus 1, Meleagrid - growth & development | Chickens | Epithelial Cells - virology | Oncogene Proteins, Viral - genetics | Virus Cultivation | Herpesvirus 1, Meleagrid - genetics | Oncogene Proteins, Viral - metabolism
Journal Article
Virology, ISSN 0042-6822, 2010, Volume 399, Issue 2, pp. 312 - 321
Abstract Marek' disease virus serotype-1, also know as Gallid herpesvirus 2 (GaHV-2), elicits T-cell lymphomas in chickens. The GaHV-2 genome encodes an...
Infectious Disease | Marek's disease virus | bZIP | T-cell lymphomas | Meq | Leucine zipper | Oncogenesis | Chicken | GaHV-2 | Dimerization | Herpesvirus | TRANSCRIPTION FACTORS | EMBRYO FIBROBLASTS | CELLS | DNA-BINDING | JUN | FOS | NUCLEAR-LOCALIZATION | HERPESVIRUS BZIP ONCOPROTEIN | VIROLOGY | MDV CDNAS | Q GENE MEQ | Leucine Zippers | Protein Multimerization | Cells, Cultured | Chickens - virology | Marek Disease - virology | Herpesvirus 2, Gallid - metabolism | Animals | Herpesvirus 2, Gallid - genetics | Lymphocytes - virology | Oncogene Proteins, Viral - genetics | Mutation | Cell Transformation, Viral | Oncogene Proteins, Viral - metabolism | Virus diseases | DNA binding proteins | Non-Hodgkin's lymphomas | T cells
Infectious Disease | Marek's disease virus | bZIP | T-cell lymphomas | Meq | Leucine zipper | Oncogenesis | Chicken | GaHV-2 | Dimerization | Herpesvirus | TRANSCRIPTION FACTORS | EMBRYO FIBROBLASTS | CELLS | DNA-BINDING | JUN | FOS | NUCLEAR-LOCALIZATION | HERPESVIRUS BZIP ONCOPROTEIN | VIROLOGY | MDV CDNAS | Q GENE MEQ | Leucine Zippers | Protein Multimerization | Cells, Cultured | Chickens - virology | Marek Disease - virology | Herpesvirus 2, Gallid - metabolism | Animals | Herpesvirus 2, Gallid - genetics | Lymphocytes - virology | Oncogene Proteins, Viral - genetics | Mutation | Cell Transformation, Viral | Oncogene Proteins, Viral - metabolism | Virus diseases | DNA binding proteins | Non-Hodgkin's lymphomas | T cells
Journal Article
Journal of Virology, ISSN 0022-538X, 09/2006, Volume 80, Issue 17, pp. 8778 - 8786
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley...
ICP4 HOMOLOG GENE | HERPESVIRUS | VIROLOGY | RNAI ENZYME COMPLEX | PROTEIN MEQ | MDV CDNAS | LYMPHOBLASTOID CELL-LINES | LYTICALLY INFECTED-CELLS | IDENTIFICATION | VIRAL-INFECTION | BAMHI-H | Fibroblasts - virology | Amino Acid Sequence | Herpesvirus 2, Gallid - physiology | Molecular Sequence Data | Viral Proteins - genetics | MicroRNAs - metabolism | Chromosome Mapping | Chick Embryo | Viral Proteins - metabolism | Marek Disease - virology | Virus Latency - physiology | Herpesvirus 2, Gallid - metabolism | Herpesvirus 2, Gallid - pathogenicity | Animals | RNA, Viral - genetics | Herpesvirus 2, Gallid - genetics | Base Sequence | Cell Line, Tumor | Oncogene Proteins, Viral - genetics | MicroRNAs - genetics | RNA, Viral - metabolism | Oncogene Proteins, Viral - metabolism | Virus Latency - genetics | Genome and Regulation of Viral Gene Expression
ICP4 HOMOLOG GENE | HERPESVIRUS | VIROLOGY | RNAI ENZYME COMPLEX | PROTEIN MEQ | MDV CDNAS | LYMPHOBLASTOID CELL-LINES | LYTICALLY INFECTED-CELLS | IDENTIFICATION | VIRAL-INFECTION | BAMHI-H | Fibroblasts - virology | Amino Acid Sequence | Herpesvirus 2, Gallid - physiology | Molecular Sequence Data | Viral Proteins - genetics | MicroRNAs - metabolism | Chromosome Mapping | Chick Embryo | Viral Proteins - metabolism | Marek Disease - virology | Virus Latency - physiology | Herpesvirus 2, Gallid - metabolism | Herpesvirus 2, Gallid - pathogenicity | Animals | RNA, Viral - genetics | Herpesvirus 2, Gallid - genetics | Base Sequence | Cell Line, Tumor | Oncogene Proteins, Viral - genetics | MicroRNAs - genetics | RNA, Viral - metabolism | Oncogene Proteins, Viral - metabolism | Virus Latency - genetics | Genome and Regulation of Viral Gene Expression
Journal Article
Basic & Clinical Pharmacology & Toxicology, ISSN 1742-7835, 05/2019, Volume 124, Issue 5, pp. 607 - 614
Glycyrrhizin is used to treat chronic hepatitis, but it also plays an important role in pseudoaldosteronism. Multidrug resistance‐associated protein 2 is...
pseudoaldosteronism | chronic hepatitis | glycyrrhetinic acid | multidrug resistance‐associated protein 2 | hypokalaemia | glycyrrhizin | multidrug resistance-associated protein 2 | ACID | LICORICE-INDUCED PSEUDOALDOSTERONISM | SERUM | PLASMA | ROLES | PHARMACOLOGY & PHARMACY | TOXICOLOGY | Medical research | Drug resistance in microorganisms | Medicine, Experimental | Bilirubin | Hepatitis C | Health aspects | Risk factors | Drugs | Glycyrrhizin | Excretion | Multidrug resistance | Viruses | MEQ protein | Risk analysis | Patients | Proteins | Serum levels | Hepatitis | Synergistic effects | Metabolites | Interferon | Hepatitis C virus | Potassium | Transporter | Age
pseudoaldosteronism | chronic hepatitis | glycyrrhetinic acid | multidrug resistance‐associated protein 2 | hypokalaemia | glycyrrhizin | multidrug resistance-associated protein 2 | ACID | LICORICE-INDUCED PSEUDOALDOSTERONISM | SERUM | PLASMA | ROLES | PHARMACOLOGY & PHARMACY | TOXICOLOGY | Medical research | Drug resistance in microorganisms | Medicine, Experimental | Bilirubin | Hepatitis C | Health aspects | Risk factors | Drugs | Glycyrrhizin | Excretion | Multidrug resistance | Viruses | MEQ protein | Risk analysis | Patients | Proteins | Serum levels | Hepatitis | Synergistic effects | Metabolites | Interferon | Hepatitis C virus | Potassium | Transporter | Age
Journal Article
Journal of Virology, ISSN 0022-538X, 08/2012, Volume 86, Issue 16, pp. 8536 - 8545
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley...
HERPESVIRUS | IN-VITRO | VIRUS | REPLICATION | VIROLOGY | PROTEIN-KINASE | CHICKEN | MEQ | INFECTION | VIL-8 | MODEL | CD4-Positive T-Lymphocytes - chemistry | Sequence Deletion | Virulence Factors - genetics | B-Lymphocytes - physiology | CD4-Positive T-Lymphocytes - physiology | Chemotaxis | Mardivirus - pathogenicity | Marek Disease - virology | Marek Disease - immunology | Marek Disease - pathology | Animals | Protein Sorting Signals - genetics | Chickens | Interleukin-2 Receptor alpha Subunit - analysis | Lymphoma - pathology | Oncogene Proteins, Viral - genetics | Virulence Factors - metabolism | Lymphoma - virology | Oncogene Proteins, Viral - metabolism | Transformation and Oncogenesis
HERPESVIRUS | IN-VITRO | VIRUS | REPLICATION | VIROLOGY | PROTEIN-KINASE | CHICKEN | MEQ | INFECTION | VIL-8 | MODEL | CD4-Positive T-Lymphocytes - chemistry | Sequence Deletion | Virulence Factors - genetics | B-Lymphocytes - physiology | CD4-Positive T-Lymphocytes - physiology | Chemotaxis | Mardivirus - pathogenicity | Marek Disease - virology | Marek Disease - immunology | Marek Disease - pathology | Animals | Protein Sorting Signals - genetics | Chickens | Interleukin-2 Receptor alpha Subunit - analysis | Lymphoma - pathology | Oncogene Proteins, Viral - genetics | Virulence Factors - metabolism | Lymphoma - virology | Oncogene Proteins, Viral - metabolism | Transformation and Oncogenesis
Journal Article
12.
Full Text
Characterization of Meq proteins from field isolates of Marek's disease virus in Japan
Infection, Genetics and Evolution, ISSN 1567-1348, 06/2013, Volume 16, pp. 137 - 143
Serotype 1 strains of Marek's disease virus (MDV-1) cause malignant lymphomas in chickens (Marek's disease; MD). Although MD has been controlled by...
Transactivation activity | Meq | Marek's disease virus | Distinct diversity | TRANSFORMED T-CELLS | INFECTIOUS DISEASES | ANTISENSE | VIRULENCE | IDENTIFICATION | TUMORS | ONCOPROTEIN MEQ | GENE | MDV CDNAS | SEROTYPE-1 | LYMPHOCYTES | Viral Proteins - chemistry | Japan | Transcriptional Activation | Viral Proteins - genetics | Viral Proteins - metabolism | Marek Disease - virology | Point Mutation | Animals | Mardivirus - genetics | Analysis of Variance | Chickens | Mardivirus - metabolism | Amino Acid Substitution - genetics | Mardivirus - classification | Virus diseases
Transactivation activity | Meq | Marek's disease virus | Distinct diversity | TRANSFORMED T-CELLS | INFECTIOUS DISEASES | ANTISENSE | VIRULENCE | IDENTIFICATION | TUMORS | ONCOPROTEIN MEQ | GENE | MDV CDNAS | SEROTYPE-1 | LYMPHOCYTES | Viral Proteins - chemistry | Japan | Transcriptional Activation | Viral Proteins - genetics | Viral Proteins - metabolism | Marek Disease - virology | Point Mutation | Animals | Mardivirus - genetics | Analysis of Variance | Chickens | Mardivirus - metabolism | Amino Acid Substitution - genetics | Mardivirus - classification | Virus diseases
Journal Article
Vaccine, ISSN 0264-410X, 2012, Volume 30, Issue 34, pp. 5151 - 5158
Highlights ► Report the first safe gene deletion vaccine for Marek's disease in chickens. ► Elimination of lymphoid organs atrophy which make the vaccine safe....
Allergy and Immunology | Marek's disease virus | Recombinant MDV | Bursal and thymus atrophy | Cell culture passage | Vaccine safety and efficacy | Meq oncogene | Vaccine parameters | MEDICINE, RESEARCH & EXPERIMENTAL | HERPESVIRUS | CONFERS PROTECTION | EFFICACY | IMMUNOLOGY | VIRULENT PLUS STRAIN | REPLICATION | GENE | EXPANSION | MEQ | INSERTIONAL MUTAGENESIS | MATERNAL ANTIBODIES | Immunohistochemistry | Spleen - virology | Spleen - immunology | Chickens - virology | Male | Marek Disease Vaccines - immunology | Marek Disease - virology | Thymus Gland - virology | Marek Disease - immunology | Gene Deletion | Thymus Gland - pathology | Female | Oncogene Proteins, Viral - genetics | Spleen - pathology | Bursa of Fabricius - pathology | Virus Activation | Oncogene Proteins, Viral - metabolism | Virus Cultivation - methods | Recombinant Proteins - metabolism | Genome, Viral | Cells, Cultured | Organ Size | Gene Dosage | Recombinant Proteins - genetics | Marek Disease - therapy | Marek Disease Vaccines - genetics | Chickens - immunology | Bursa of Fabricius - virology | Bursa of Fabricius - immunology | Animals | Recombinant Proteins - immunology | Antibodies, Viral - immunology | Thymus Gland - immunology | Oncogene Proteins, Viral - immunology
Allergy and Immunology | Marek's disease virus | Recombinant MDV | Bursal and thymus atrophy | Cell culture passage | Vaccine safety and efficacy | Meq oncogene | Vaccine parameters | MEDICINE, RESEARCH & EXPERIMENTAL | HERPESVIRUS | CONFERS PROTECTION | EFFICACY | IMMUNOLOGY | VIRULENT PLUS STRAIN | REPLICATION | GENE | EXPANSION | MEQ | INSERTIONAL MUTAGENESIS | MATERNAL ANTIBODIES | Immunohistochemistry | Spleen - virology | Spleen - immunology | Chickens - virology | Male | Marek Disease Vaccines - immunology | Marek Disease - virology | Thymus Gland - virology | Marek Disease - immunology | Gene Deletion | Thymus Gland - pathology | Female | Oncogene Proteins, Viral - genetics | Spleen - pathology | Bursa of Fabricius - pathology | Virus Activation | Oncogene Proteins, Viral - metabolism | Virus Cultivation - methods | Recombinant Proteins - metabolism | Genome, Viral | Cells, Cultured | Organ Size | Gene Dosage | Recombinant Proteins - genetics | Marek Disease - therapy | Marek Disease Vaccines - genetics | Chickens - immunology | Bursa of Fabricius - virology | Bursa of Fabricius - immunology | Animals | Recombinant Proteins - immunology | Antibodies, Viral - immunology | Thymus Gland - immunology | Oncogene Proteins, Viral - immunology
Journal Article
Virus Research, ISSN 0168-1702, 2009, Volume 142, Issue 1, pp. 57 - 67
(GaHV-2), commonly known as Marek's disease virus serotype-1 (MDV-1), causes T cell lymphomas in chickens. Vaccines prepared from the attenuated CVI988/Rispens...
Transformation | CVI988/Rispens | T cell lymphoma | Oncoprotein | Meq | Vaccine | Marek's diseases virus | Transactivation | b-ZIP protein | TRANSFORMED T-CELLS | SEQUENCE-ANALYSIS | CONFERS PROTECTION | VIL-8 DELETION MUTANT | HERPESVIRUS ONCOPROTEIN MEQ | VIRULENT PLUS STRAIN | NUCLEAR-LOCALIZATION | VIROLOGY | DNA VACCINE | GENE | SINGLE-MINDED 2S | Cell Line | Promoter Regions, Genetic | Marek Disease - genetics | Marek Disease - metabolism | Rats | Marek Disease Vaccines - genetics | Poultry Diseases - virology | Chick Embryo | Poultry Diseases - metabolism | Marek Disease - virology | Marek Disease Vaccines - metabolism | Herpesvirus 2, Gallid - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Animals | Herpesvirus 2, Gallid - genetics | Chickens | Protein Binding | Oncogene Proteins, Viral - genetics | Mice | Proto-Oncogene Proteins c-bcl-2 - genetics | Cell Transformation, Viral | Poultry Diseases - genetics | Oncogene Proteins, Viral - metabolism | Virus diseases | Proteins | Amino acids | Lymphomas | Vaccines | T cells | Protein binding
Transformation | CVI988/Rispens | T cell lymphoma | Oncoprotein | Meq | Vaccine | Marek's diseases virus | Transactivation | b-ZIP protein | TRANSFORMED T-CELLS | SEQUENCE-ANALYSIS | CONFERS PROTECTION | VIL-8 DELETION MUTANT | HERPESVIRUS ONCOPROTEIN MEQ | VIRULENT PLUS STRAIN | NUCLEAR-LOCALIZATION | VIROLOGY | DNA VACCINE | GENE | SINGLE-MINDED 2S | Cell Line | Promoter Regions, Genetic | Marek Disease - genetics | Marek Disease - metabolism | Rats | Marek Disease Vaccines - genetics | Poultry Diseases - virology | Chick Embryo | Poultry Diseases - metabolism | Marek Disease - virology | Marek Disease Vaccines - metabolism | Herpesvirus 2, Gallid - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Animals | Herpesvirus 2, Gallid - genetics | Chickens | Protein Binding | Oncogene Proteins, Viral - genetics | Mice | Proto-Oncogene Proteins c-bcl-2 - genetics | Cell Transformation, Viral | Poultry Diseases - genetics | Oncogene Proteins, Viral - metabolism | Virus diseases | Proteins | Amino acids | Lymphomas | Vaccines | T cells | Protein binding
Journal Article
Avian Diseases, ISSN 0005-2086, 2013, Volume 57, Issue 2, pp. 555 - 561
In spite of the intensive vaccination policy against the Marek's disease virus (MDV) in Egypt, the Egyptian poultry flocks are still suffering from several...
Meq | MDV | PCR | Egypt | Polymerase chain reaction | Vaccination | DNA | Viral diseases | Gallid herpesvirus 2 | Phylogenetics | Viruses | Amino acids | Flocks | Tumors | TRANSFORMATION | STRAINS | CELLS | GLYCOPROTEIN-L | VIRULENCE | AVIAN-LEUKOSIS-VIRUS | POLYMERASE-CHAIN-REACTION | REPLICATION | MEQ GENE | VETERINARY SCIENCES | Antigens, Viral - metabolism | Oncogene Proteins, Viral - chemistry | Molecular Sequence Data | Antigens, Viral - genetics | Feathers - virology | Phylogeny | Marek Disease - virology | Herpesvirus 2, Gallid - metabolism | Neoplasms - virology | Viral Envelope Proteins - metabolism | Oncogene Proteins, Viral - genetics | Oncogene Proteins, Viral - metabolism | Amino Acid Sequence | Viral Envelope Proteins - genetics | Antigens, Viral - chemistry | Poultry Diseases - virology | Sequence Alignment - veterinary | Animals | Polymerase Chain Reaction - veterinary | Herpesvirus 2, Gallid - genetics | Chickens | Viral Envelope Proteins - chemistry | Sequence Analysis, DNA - veterinary | Herpesvirus 2, Gallid - chemistry
Meq | MDV | PCR | Egypt | Polymerase chain reaction | Vaccination | DNA | Viral diseases | Gallid herpesvirus 2 | Phylogenetics | Viruses | Amino acids | Flocks | Tumors | TRANSFORMATION | STRAINS | CELLS | GLYCOPROTEIN-L | VIRULENCE | AVIAN-LEUKOSIS-VIRUS | POLYMERASE-CHAIN-REACTION | REPLICATION | MEQ GENE | VETERINARY SCIENCES | Antigens, Viral - metabolism | Oncogene Proteins, Viral - chemistry | Molecular Sequence Data | Antigens, Viral - genetics | Feathers - virology | Phylogeny | Marek Disease - virology | Herpesvirus 2, Gallid - metabolism | Neoplasms - virology | Viral Envelope Proteins - metabolism | Oncogene Proteins, Viral - genetics | Oncogene Proteins, Viral - metabolism | Amino Acid Sequence | Viral Envelope Proteins - genetics | Antigens, Viral - chemistry | Poultry Diseases - virology | Sequence Alignment - veterinary | Animals | Polymerase Chain Reaction - veterinary | Herpesvirus 2, Gallid - genetics | Chickens | Viral Envelope Proteins - chemistry | Sequence Analysis, DNA - veterinary | Herpesvirus 2, Gallid - chemistry
Journal Article
PLOS PATHOGENS, ISSN 1553-7366, 09/2019, Volume 15, Issue 9, p. e1007999
Author summary Marek's disease virus (MDV) is an avian oncogenic herpesvirus that causes a fatal disease in poultry worldwide. Chickens infected with MDV...
TRANSFORMATION | ACTIVATION | MAREKS-DISEASE VIRUS | RECOGNITION | MICROBIOLOGY | ONCOPROTEIN MEQ | PARTNERS | RESPONSES | ANTIVIRAL DEFENSE | VIROLOGY | GENE | EXPRESSION | PARASITOLOGY | Immune response | Viral proteins | Analysis | Development and progression | Regulation | Host-virus relationships | Marek's disease | Identification and classification | Infection | DNA | Lymphomas | Interferon | Biological response modifiers | T cells | Health aspects | Veterinary colleges | Biotechnology | Disease | β-Interferon | Poultry | CD8 antigen | Genes | Viruses | Infections | Lymphocytes T | Vaccines | Kinases | Veterinary medicine | Proteins | Stimulators | Lymphocytes | Cyclic GMP | Tumorigenesis | Sensors | Deoxyribonucleic acid--DNA | Pathogens | Cytomegalovirus | AMP | MEQ protein | Gene expression | Lymphoma | Interferon regulatory factor 7 | Herpes viruses | Replication | Food safety | Laboratory animals | Tumors | Deoxyribonucleic acid
TRANSFORMATION | ACTIVATION | MAREKS-DISEASE VIRUS | RECOGNITION | MICROBIOLOGY | ONCOPROTEIN MEQ | PARTNERS | RESPONSES | ANTIVIRAL DEFENSE | VIROLOGY | GENE | EXPRESSION | PARASITOLOGY | Immune response | Viral proteins | Analysis | Development and progression | Regulation | Host-virus relationships | Marek's disease | Identification and classification | Infection | DNA | Lymphomas | Interferon | Biological response modifiers | T cells | Health aspects | Veterinary colleges | Biotechnology | Disease | β-Interferon | Poultry | CD8 antigen | Genes | Viruses | Infections | Lymphocytes T | Vaccines | Kinases | Veterinary medicine | Proteins | Stimulators | Lymphocytes | Cyclic GMP | Tumorigenesis | Sensors | Deoxyribonucleic acid--DNA | Pathogens | Cytomegalovirus | AMP | MEQ protein | Gene expression | Lymphoma | Interferon regulatory factor 7 | Herpes viruses | Replication | Food safety | Laboratory animals | Tumors | Deoxyribonucleic acid
Journal Article
17.
Full Text
Characterization of Meq proteins from field isolates of Marek’s disease virus in Japan
Infection, Genetics and Evolution, ISSN 1567-1348, 06/2013, Volume 16, pp. 137 - 143
► MDV-1 field isolates have tended to increase in virulence in some countries. ► In the gene, there are distinct diversity that correlate with the virulence. ►...
Transactivation activity | Meq | Marek’s disease virus | Distinct diversity
Transactivation activity | Meq | Marek’s disease virus | Distinct diversity
Journal Article
Avian Diseases, ISSN 0005-2086, 2013, Volume 57, Issue 2, pp. 387 - 394
In addition to tumors, Marek's disease (MD) virus (MDV) can induce a variety of syndromes linked to the central nervous system. In fact, early descriptions of...
neurovirulence | Marek's disease | MDV1 | Protein isoforms | Nervous system diseases | Exons | Chickens | Viral diseases | Nerves | Gallid herpesvirus 2 | Viruses | Lesions | Central nervous system viral diseases | Neurovirulence | ACUTE FORM | STRAINS | TRANSFORMATION | IMMEDIATE-EARLY GENE | TRANSIENT PARALYSIS | CHICKENS | NERVOUS-SYSTEM LESIONS | REPLICATION | ONCOGENICITY | VETERINARY SCIENCES | MEQ PROTEIN | Specific Pathogen-Free Organisms | Virulence Factors - genetics | RNA, Messenger - genetics | Cells, Cultured | Viral Proteins - genetics | Poultry Diseases - virology | RNA Caps - metabolism | RNA, Messenger - metabolism | Chick Embryo | Viral Proteins - metabolism | Marek Disease - virology | Herpesvirus 2, Gallid - metabolism | Herpesvirus 2, Gallid - pathogenicity | Immediate-Early Proteins - metabolism | Animals | Immediate-Early Proteins - genetics | Herpesvirus 2, Gallid - genetics | Gene Expression Regulation, Viral | Gene Deletion | Transcription, Genetic | Virulence Factors - metabolism | Nervous System - virology | RNA Caps - genetics
neurovirulence | Marek's disease | MDV1 | Protein isoforms | Nervous system diseases | Exons | Chickens | Viral diseases | Nerves | Gallid herpesvirus 2 | Viruses | Lesions | Central nervous system viral diseases | Neurovirulence | ACUTE FORM | STRAINS | TRANSFORMATION | IMMEDIATE-EARLY GENE | TRANSIENT PARALYSIS | CHICKENS | NERVOUS-SYSTEM LESIONS | REPLICATION | ONCOGENICITY | VETERINARY SCIENCES | MEQ PROTEIN | Specific Pathogen-Free Organisms | Virulence Factors - genetics | RNA, Messenger - genetics | Cells, Cultured | Viral Proteins - genetics | Poultry Diseases - virology | RNA Caps - metabolism | RNA, Messenger - metabolism | Chick Embryo | Viral Proteins - metabolism | Marek Disease - virology | Herpesvirus 2, Gallid - metabolism | Herpesvirus 2, Gallid - pathogenicity | Immediate-Early Proteins - metabolism | Animals | Immediate-Early Proteins - genetics | Herpesvirus 2, Gallid - genetics | Gene Expression Regulation, Viral | Gene Deletion | Transcription, Genetic | Virulence Factors - metabolism | Nervous System - virology | RNA Caps - genetics
Journal Article