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index medicus (222) 222
humans (147) 147
animals (130) 130
mice (97) 97
matrix metalloproteinases (84) 84
macrophage metalloelastase (79) 79
metalloelastase (75) 75
male (73) 73
expression (71) 71
female (61) 61
inflammation (48) 48
matrix metalloproteinase 12 - metabolism (47) 47
metalloelastase mmp-12 (46) 46
matrix metalloproteinase 12 (45) 45
matrix metalloproteinase 12 - genetics (44) 44
biochemistry & molecular biology (37) 37
macrophage metalloelastase mmp-12 (37) 37
macrophages (37) 37
matrix metalloproteinase (37) 37
obstructive pulmonary-disease (37) 37
disease models, animal (36) 36
mmp-12 (35) 35
immunohistochemistry (34) 34
middle aged (34) 34
mice, inbred c57bl (33) 33
gene-expression (32) 32
emphysema (31) 31
necrosis-factor-alpha (31) 31
analysis (30) 30
cell biology (30) 30
abridged index medicus (29) 29
matrix metalloproteinases - metabolism (29) 29
oncology (29) 29
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aged (28) 28
respiratory system (28) 28
tissue inhibitor (28) 28
cancer (27) 27
chronic obstructive pulmonary disease (26) 26
matrix metalloproteinase inhibitors (24) 24
matrix metalloproteinase-12 (24) 24
mice, knockout (24) 24
pharmacology & pharmacy (24) 24
metalloendopeptidases - genetics (23) 23
cells (22) 22
metalloendopeptidases - metabolism (22) 22
metastasis (22) 22
extracellular-matrix (21) 21
human macrophage metalloelastase (21) 21
immunology (21) 21
angiogenesis (20) 20
elastase (20) 20
pathology (20) 20
up-regulation (20) 20
article (19) 19
inhibitors (19) 19
angiostatin (18) 18
gene expression (18) 18
localization (18) 18
rna, messenger - metabolism (18) 18
dermatology (17) 17
invasion (17) 17
macrophages - enzymology (17) 17
metalloproteinase (17) 17
proteins (17) 17
alveolar macrophages (16) 16
apoptosis (16) 16
lung - pathology (16) 16
macrophage elastase (16) 16
macrophages - metabolism (16) 16
reverse transcriptase polymerase chain reaction (16) 16
smoking - adverse effects (16) 16
cells, cultured (15) 15
enzymes (15) 15
extracellular matrix (15) 15
gastroenterology & hepatology (15) 15
lung (15) 15
atherosclerosis (14) 14
cigarette smoke (14) 14
cigarette-smoke (14) 14
connective-tissue breakdown (14) 14
copd (14) 14
inflammatory-bowel-disease (14) 14
macrophage (14) 14
prognosis (14) 14
proteases (14) 14
research (14) 14
activation (13) 13
airway inflammation (13) 13
carcinoma (13) 13
cell line, tumor (13) 13
chemistry, medicinal (13) 13
genetic aspects (13) 13
inhibitor (13) 13
macrophages - pathology (13) 13
matrix metalloproteinases - genetics (13) 13
medicine, research & experimental (13) 13
risk factors (13) 13
smoke-induced emphysema (13) 13
cell line (12) 12
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Macrophage elastase (MMP-12): a pro-inflammatory mediator?, 12/2005
As many metalloproteinases (MMPs), macrophage elastase (MMP-12) is able to degrade extracellular matrix components such as elastin and is involved in tissue... 
matrix metalloproteianse - metalloelastase - airway inflammation - chronic obstructive pulmonary disease
Journal
NATURE REVIEWS CANCER, ISSN 1474-175X, 10/2007, Volume 7, Issue 10, pp. 800 - 808
Proteases have long been associated with cancer progression because of their ability to degrade extracellular matrices, which facilitates invasion and... 
CELL LUNG-CANCER | MATRIX METALLOPROTEINASES | PROMOTER HYPERMETHYLATION | ONCOLOGY | HUMAN MACROPHAGE METALLOELASTASE | PROSTATE-SPECIFIC ANTIGEN | GENE-EXPRESSION | SERINE-PROTEASE | HUMAN BREAST-CANCER | NF-KAPPA-B | DIPEPTIDYL PEPTIDASE-IV
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 12/2017, Volume 199, Issue 12, pp. 4023 - 4035
Irreversible tissue recession in chronic inflammatory diseases is associated with dysregulated immune activation and production of tissue degradative enzymes.... 
ACTIVATION | MACROPHAGES | ORGANOTYPIC MODEL | RECEPTOR | KERATINOCYTES | INDUCTION | SPECTRUM | IMMUNOLOGY | METALLOELASTASE | EXPRESSION | INSIGHTS
Journal Article
NATURE, ISSN 0028-0836, 03/2003, Volume 422, Issue 6928, pp. 169 - 173
Integrins are heterodimeric cell-surface proteins that regulate cell growth, migration and survival. We have shown previously that the epithelial-restricted... 
CYTOPLASMIC DOMAIN | LOCALIZATION | MACROPHAGE METALLOELASTASE | INHIBITION | MULTIDISCIPLINARY SCIENCES | MICE | FOCAL CONTACTS | EXPRESSION | LUNG INFLAMMATION | SUBUNIT | REVEALS
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 11/2018, Volume 119, Issue 11, pp. 8694 - 8712
Metastasis is known to be one of the important factors associated with cancer‐related deaths worldwide. Several cellular and molecular targets are involved in... 
micro‐RNAs | cancer | metastasis | matrix metalloproteinases | micro-RNAs | CIRCULATING MICRORNAS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLIOMA-CELL INVASION | HUMAN LUNG-CANCER | TUMOR-SUPPRESSOR GENE | DOWN-REGULATION | CELL BIOLOGY | BREAST-CANCER | HEPATOCELLULAR-CARCINOMA | HUMAN MACROPHAGE METALLOELASTASE | GASTRIC-CANCER | UP-REGULATION | Metastasis | Cancer
Journal Article
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, ISSN 1044-1549, 04/2009, Volume 40, Issue 4, pp. 482 - 490
Interleukin-1 beta (IL-1 beta), a proinflammatory cytokine, is elevated in cigarette smokers. To determine whether IL-1 beta plays a role in the pathogenesis... 
LUNG | MACROPHAGE METALLOELASTASE | TNF-alpha | BIOCHEMISTRY & MOLECULAR BIOLOGY | apoptosis | INDUCED INFLAMMATION | IL-1 beta | NECROSIS-FACTOR-ALPHA | CELL APOPTOSIS | cigarette smoke | emphysema | BETA | CELL BIOLOGY | OBSTRUCTIVE PULMONARY-DISEASE | CONNECTIVE-TISSUE BREAKDOWN | RESPIRATORY SYSTEM | IL-1-BETA | EXPRESSION
Journal Article
JOURNAL OF HEPATOLOGY, ISSN 0168-8278, 04/2017, Volume 66, Issue 4, pp. 787 - 797
Journal Article
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, ISSN 0022-2828, 06/2019, Volume 131, pp. 41 - 52
Background: Various immune cells are involved in different phases of cardiac repair after myocardial infarction (MI). Especially, Ly6C(low )M2-like macrophages... 
Myocardial infarction | Myocardial fibrosis | Myocardial inflammation | M2 MACROPHAGES | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | CELL BIOLOGY | HEART | INHIBITION | CARDIAC RUPTURE | INFLAMMATION | MMP-12 | ISCHEMIA-REPERFUSION | TARGETED DELETION | METALLOELASTASE | T-CELLS
Journal Article
Cellular Signalling, ISSN 0898-6568, 02/2019, Volume 54, pp. 191 - 199
Photodamage in chronically sun-exposed skin manifests clinically as deep wrinkles and histologically as extensive remodelling of the dermal extracellular... 
Atomic force microscopy (AFM) | Photoageing | Fibrillin microfibrils | Gel electrophoresis | Ultraviolet radiation (UVR) | Reactive oxygen species (ROS) | Matrix metalloproteinase (MMP) | Extracellular matrix | COLLAGEN | HUMAN SKIN | FIBRILLIN | MICROFIBRILS | CELL BIOLOGY | PATHOGENESIS | IRRADIATION | METALLOELASTASE MMP-12 | DEGRADATION | DISSOLVED-OXYGEN
Journal Article
JOURNAL OF CELL SCIENCE, ISSN 0021-9533, 09/2013, Volume 126, Issue 17, pp. 3948 - 3960
Corneal scarring due to injury is a leading cause of blindness worldwide and results from dysregulated inflammation and angiogenesis during wound healing. Here... 
Matrix metalloproteinases | BONE-MARROW | MACROPHAGE | MOUSE | Corneal inflammation | CELL BIOLOGY | Wound repair | EPITHELIAL-CELLS | GENE-EXPRESSION | MMP-12 | MICE | NEOVASCULARIZATION | METALLOELASTASE | TUMOR-GROWTH
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 08/2006, Volume 66, Issue 16, pp. 7968 - 7975
We used a customized Affymetrix protease microarray (Hu/Mu ProtIn chip) designed to distinguish human and mouse genes to analyze the expression of proteases... 
ANGIOGENESIS | ONCOLOGY | CATHEPSIN-K | ANGIOSTATIN | INTEGRIN | MICE | PROTEOLYSIS | METALLOELASTASE | METALLOPROTEINASES | EXPRESSION | CARCINOMA
Journal Article
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 07/2015, Volume 35, Issue 7, pp. 1723 - 1731
Journal Article
The Journal of Thoracic and Cardiovascular Surgery, ISSN 0022-5223, 05/2018, Volume 155, Issue 5, pp. 2164 - 2175.e1
Past studies are inconsistent with regard to the role of matrix metalloproteinase 12 in lung tumorigenesis. This is due, in part, to differential tumorigenesis... 
lung | non–small cell lung cancer | orthotopic animal model | tumor microenvironment | non-small cell lung cancer | MACROPHAGE METALLOELASTASE MMP-12 | SURGERY | CARDIAC & CARDIOVASCULAR SYSTEMS | METASTASIS | ADENOCARCINOMA | CANCER | INVASION | RESPIRATORY SYSTEM | GROWTH | SQUAMOUS-CELL CARCINOMA | GENE-EXPRESSION | Index Medicus | Abridged Index Medicus
Journal Article
Scientific reports, ISSN 2045-2322, 08/2019, Volume 9, Issue 1, pp. 11579 - 13
Journal Article
Journal of Biomolecular Structure and Dynamics, ISSN 0739-1102, 07/2019, Volume 37, Issue 10, pp. 2627 - 2640
Journal Article
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