Gastroenterology Clinics of North America, ISSN 0889-8553, 09/2016, Volume 45, Issue 3, pp. 487 - 507
Neuroendocrine tumors are increasingly diagnosed, either incidentally as part of screening processes, or for symptoms, which have commonly been mistaken for...
Therapy | Tumor | Carcinoid | Diagnostics | Multimodal | Neuroendocrine | METASTATIC CARCINOID-TUMORS | SOMATOSTATIN ANALOGS | PROGNOSTIC-FACTORS | LONG-TERM OUTCOMES | GASTROINTESTINAL-TRACT | HEPATIC ARTERIAL CHEMOEMBOLIZATION | CHROMOGRANIN-A | LIVER METASTASES | PHASE-II TRIAL | RECEPTOR RADIONUCLIDE THERAPY | GASTROENTEROLOGY & HEPATOLOGY | Pancreatic Neoplasms - metabolism | Pancreatic Neoplasms - diagnosis | Humans | Tomography, X-Ray Computed | Antineoplastic Agents - therapeutic use | Liver Neoplasms - therapy | Neuroendocrine Tumors - diagnosis | Embolization, Therapeutic | Organometallic Compounds | Gastrointestinal Neoplasms - pathology | Antineoplastic Agents, Hormonal - therapeutic use | Chromogranin A - metabolism | Receptors, Somatostatin - metabolism | Liver Neoplasms - secondary | Radiopharmaceuticals | Gastrointestinal Neoplasms - metabolism | Neuroendocrine Tumors - metabolism | Pancreatic Neoplasms - pathology | Hepatic Artery | Hydroxyindoleacetic Acid - metabolism | Gastrointestinal Neoplasms - diagnosis | Gastrointestinal Neoplasms - therapy | Octreotide - therapeutic use | Malignant Carcinoid Syndrome - therapy | Positron Emission Tomography Computed Tomography | Magnetic Resonance Imaging | Metastasectomy | Digestive System Surgical Procedures | Neuroendocrine Tumors - secondary | Serotonin - metabolism | Gallium Radioisotopes | Fluorodeoxyglucose F18 | Neuroendocrine Tumors - therapy | Neoplasm Staging | Pancreatic Neoplasms - therapy
Therapy | Tumor | Carcinoid | Diagnostics | Multimodal | Neuroendocrine | METASTATIC CARCINOID-TUMORS | SOMATOSTATIN ANALOGS | PROGNOSTIC-FACTORS | LONG-TERM OUTCOMES | GASTROINTESTINAL-TRACT | HEPATIC ARTERIAL CHEMOEMBOLIZATION | CHROMOGRANIN-A | LIVER METASTASES | PHASE-II TRIAL | RECEPTOR RADIONUCLIDE THERAPY | GASTROENTEROLOGY & HEPATOLOGY | Pancreatic Neoplasms - metabolism | Pancreatic Neoplasms - diagnosis | Humans | Tomography, X-Ray Computed | Antineoplastic Agents - therapeutic use | Liver Neoplasms - therapy | Neuroendocrine Tumors - diagnosis | Embolization, Therapeutic | Organometallic Compounds | Gastrointestinal Neoplasms - pathology | Antineoplastic Agents, Hormonal - therapeutic use | Chromogranin A - metabolism | Receptors, Somatostatin - metabolism | Liver Neoplasms - secondary | Radiopharmaceuticals | Gastrointestinal Neoplasms - metabolism | Neuroendocrine Tumors - metabolism | Pancreatic Neoplasms - pathology | Hepatic Artery | Hydroxyindoleacetic Acid - metabolism | Gastrointestinal Neoplasms - diagnosis | Gastrointestinal Neoplasms - therapy | Octreotide - therapeutic use | Malignant Carcinoid Syndrome - therapy | Positron Emission Tomography Computed Tomography | Magnetic Resonance Imaging | Metastasectomy | Digestive System Surgical Procedures | Neuroendocrine Tumors - secondary | Serotonin - metabolism | Gallium Radioisotopes | Fluorodeoxyglucose F18 | Neuroendocrine Tumors - therapy | Neoplasm Staging | Pancreatic Neoplasms - therapy
Journal Article
Pancreas, ISSN 0885-3177, 08/2010, Volume 39, Issue 6, pp. 753 - 766
Well-differentiated neuroendocrine tumors (NETs) of the jejunum, ileum, and appendix are also collectively known as midgut carcinoids. Similar to NETs in...
ileum | jejunum | cecum | appendix | neuroendocrine tumors | METASTATIC CARCINOID-TUMORS | RISK-FACTORS | ENDOCRINE TUMORS | PHASE-II | CHROMOGRANIN-A | SMALL-INTESTINAL CANCER | ANESTHETIC MANAGEMENT | 5-HYDROXYINDOLEACETIC ACID | SOMATOSTATIN RECEPTOR SCINTIGRAPHY | RECOMBINANT INTERFERON-ALPHA | GASTROENTEROLOGY & HEPATOLOGY | Cecum - pathology | Ileum - pathology | Jejunum - pathology | Appendix - pathology | Humans | Neuroendocrine Tumors - diagnosis | Intestinal Neoplasms - diagnosis
ileum | jejunum | cecum | appendix | neuroendocrine tumors | METASTATIC CARCINOID-TUMORS | RISK-FACTORS | ENDOCRINE TUMORS | PHASE-II | CHROMOGRANIN-A | SMALL-INTESTINAL CANCER | ANESTHETIC MANAGEMENT | 5-HYDROXYINDOLEACETIC ACID | SOMATOSTATIN RECEPTOR SCINTIGRAPHY | RECOMBINANT INTERFERON-ALPHA | GASTROENTEROLOGY & HEPATOLOGY | Cecum - pathology | Ileum - pathology | Jejunum - pathology | Appendix - pathology | Humans | Neuroendocrine Tumors - diagnosis | Intestinal Neoplasms - diagnosis
Journal Article
Pancreas, ISSN 0885-3177, 08/2010, Volume 39, Issue 6, pp. 775 - 783
Pheochromocytomas, intra-adrenal paraganglioma, and extra-adrenal sympathetic and parasympathetic paragangliomas are neuroendocrine tumors derived from adrenal...
medullary thyroid cancer | pheochromocytoma | neuroendocrine tumors | paraganglioma | LYMPH-NODE DISSECTION | MALIGNANT PHEOCHROMOCYTOMAS | METASTATIC PHEOCHROMOCYTOMA | GENOTYPE-PHENOTYPE CORRELATIONS | I-123 METAIODOBENZYLGUANIDINE | ENDOCRINE NEOPLASIA TYPE-2 | BIOCHEMICAL-DIAGNOSIS | POSITRON-EMISSION-TOMOGRAPHY | FUNCTIONAL PARAGANGLIOMA | LOCALIZING PHEOCHROMOCYTOMAS | GASTROENTEROLOGY & HEPATOLOGY | Thyroid Neoplasms - therapy | Thyroid Neoplasms - diagnosis | Paraganglioma - therapy | Pheochromocytoma - diagnosis | Humans | Neuroendocrine Tumors - diagnosis | Neuroendocrine Tumors - therapy | Paraganglioma - diagnosis | Pheochromocytoma - therapy
medullary thyroid cancer | pheochromocytoma | neuroendocrine tumors | paraganglioma | LYMPH-NODE DISSECTION | MALIGNANT PHEOCHROMOCYTOMAS | METASTATIC PHEOCHROMOCYTOMA | GENOTYPE-PHENOTYPE CORRELATIONS | I-123 METAIODOBENZYLGUANIDINE | ENDOCRINE NEOPLASIA TYPE-2 | BIOCHEMICAL-DIAGNOSIS | POSITRON-EMISSION-TOMOGRAPHY | FUNCTIONAL PARAGANGLIOMA | LOCALIZING PHEOCHROMOCYTOMAS | GASTROENTEROLOGY & HEPATOLOGY | Thyroid Neoplasms - therapy | Thyroid Neoplasms - diagnosis | Paraganglioma - therapy | Pheochromocytoma - diagnosis | Humans | Neuroendocrine Tumors - diagnosis | Neuroendocrine Tumors - therapy | Paraganglioma - diagnosis | Pheochromocytoma - therapy
Journal Article
Nature Medicine, ISSN 1078-8956, 06/2017, Volume 23, Issue 6, pp. 664 - 673
Neuroendocrine (NE) cancers are a diverse group of neoplasms typically diagnosed and treated on the basis of their site of origin. This Perspective focuses on...
MOLECULAR CHARACTERIZATION | MEDICINE, RESEARCH & EXPERIMENTAL | PANCREATIC ENDOCRINE NEOPLASMS | TRANSGENIC MOUSE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTIANDROGEN RESISTANCE | CONDITIONAL MOUSE MODEL | AURORA KINASE | METASTATIC PROSTATE-CANCER | T-ANTIGEN | CELL BIOLOGY | CELL LUNG-CANCER | N-MYC | Lung Neoplasms - drug therapy | Colonic Neoplasms - genetics | Carcinoma, Small Cell - genetics | Colonic Neoplasms - drug therapy | Epigenesis, Genetic | Humans | Male | Antineoplastic Agents - therapeutic use | Molecular Targeted Therapy | Tumor Suppressor Protein p53 - genetics | Ovarian Neoplasms - genetics | Neoplasms, Glandular and Epithelial - genetics | Prostatic Neoplasms - genetics | Urinary Bladder Neoplasms - genetics | Female | Cell Differentiation | Retinoblastoma Binding Proteins - genetics | Ovarian Neoplasms - drug therapy | Prostatic Neoplasms - drug therapy | Triazoles - therapeutic use | Lung Neoplasms - genetics | Antibodies, Monoclonal, Humanized - therapeutic use | Carcinoma, Neuroendocrine - drug therapy | Carcinoma, Small Cell - drug therapy | Carcinogenesis - genetics | Head and Neck Neoplasms - drug therapy | Carcinoma, Neuroendocrine - genetics | Uterine Cervical Neoplasms - drug therapy | Urinary Bladder Neoplasms - drug therapy | Uterine Cervical Neoplasms - genetics | Disease Progression | Azepines - therapeutic use | Neuroendocrine Tumors - genetics | Proto-Oncogene Proteins c-met - genetics | Cell Lineage | Cell Plasticity - genetics | Esophageal Neoplasms - genetics | Pyrimidines - therapeutic use | Neuroendocrine Tumors - drug therapy | Head and Neck Neoplasms - genetics | Proto-Oncogene Proteins c-myc - genetics | Ubiquitin-Protein Ligases - genetics | Benzodiazepines - therapeutic use | Esophageal Neoplasms - drug therapy | Proteins | Research | Health aspects | Carcinogenesis | Gastrin
MOLECULAR CHARACTERIZATION | MEDICINE, RESEARCH & EXPERIMENTAL | PANCREATIC ENDOCRINE NEOPLASMS | TRANSGENIC MOUSE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTIANDROGEN RESISTANCE | CONDITIONAL MOUSE MODEL | AURORA KINASE | METASTATIC PROSTATE-CANCER | T-ANTIGEN | CELL BIOLOGY | CELL LUNG-CANCER | N-MYC | Lung Neoplasms - drug therapy | Colonic Neoplasms - genetics | Carcinoma, Small Cell - genetics | Colonic Neoplasms - drug therapy | Epigenesis, Genetic | Humans | Male | Antineoplastic Agents - therapeutic use | Molecular Targeted Therapy | Tumor Suppressor Protein p53 - genetics | Ovarian Neoplasms - genetics | Neoplasms, Glandular and Epithelial - genetics | Prostatic Neoplasms - genetics | Urinary Bladder Neoplasms - genetics | Female | Cell Differentiation | Retinoblastoma Binding Proteins - genetics | Ovarian Neoplasms - drug therapy | Prostatic Neoplasms - drug therapy | Triazoles - therapeutic use | Lung Neoplasms - genetics | Antibodies, Monoclonal, Humanized - therapeutic use | Carcinoma, Neuroendocrine - drug therapy | Carcinoma, Small Cell - drug therapy | Carcinogenesis - genetics | Head and Neck Neoplasms - drug therapy | Carcinoma, Neuroendocrine - genetics | Uterine Cervical Neoplasms - drug therapy | Urinary Bladder Neoplasms - drug therapy | Uterine Cervical Neoplasms - genetics | Disease Progression | Azepines - therapeutic use | Neuroendocrine Tumors - genetics | Proto-Oncogene Proteins c-met - genetics | Cell Lineage | Cell Plasticity - genetics | Esophageal Neoplasms - genetics | Pyrimidines - therapeutic use | Neuroendocrine Tumors - drug therapy | Head and Neck Neoplasms - genetics | Proto-Oncogene Proteins c-myc - genetics | Ubiquitin-Protein Ligases - genetics | Benzodiazepines - therapeutic use | Esophageal Neoplasms - drug therapy | Proteins | Research | Health aspects | Carcinogenesis | Gastrin
Journal Article
Annals of Surgery, ISSN 0003-4932, 05/2013, Volume 257, Issue 5, pp. 807 - 815
Objective: The purpose of this study was to assess outcomes and indications in a large cohort of patients who underwent liver transplantation (LT) for liver...
multivariate analysis | liver transplantation | neuroendocrine tumors | prognostic study | SURVIVAL | SURGERY | MANAGEMENT | PROGNOSTIC-FACTORS | EXPERIENCE | METASTATIC ENDOCRINE TUMORS | Multivariate Analysis | Liver Transplantation | Prognosis | Follow-Up Studies | Europe | Humans | Middle Aged | Liver Neoplasms - surgery | Male | Treatment Outcome | Liver Neoplasms - mortality | Patient Selection | Young Adult | Neuroendocrine Tumors - secondary | Adolescent | Neuroendocrine Tumors - mortality | Survival Analysis | Adult | Female | Neuroendocrine Tumors - surgery | Registries | Aged | Retrospective Studies | Liver Neoplasms - secondary
multivariate analysis | liver transplantation | neuroendocrine tumors | prognostic study | SURVIVAL | SURGERY | MANAGEMENT | PROGNOSTIC-FACTORS | EXPERIENCE | METASTATIC ENDOCRINE TUMORS | Multivariate Analysis | Liver Transplantation | Prognosis | Follow-Up Studies | Europe | Humans | Middle Aged | Liver Neoplasms - surgery | Male | Treatment Outcome | Liver Neoplasms - mortality | Patient Selection | Young Adult | Neuroendocrine Tumors - secondary | Adolescent | Neuroendocrine Tumors - mortality | Survival Analysis | Adult | Female | Neuroendocrine Tumors - surgery | Registries | Aged | Retrospective Studies | Liver Neoplasms - secondary
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 03/2011, Volume 29, Issue 7, pp. 934 - 943
Neuroendocrine tumors (NETs) arise from a variety of anatomic sites and share the capacity for production of hormones and vasoactive peptides. Because of their...
METASTATIC CARCINOID-TUMORS | GRADING SYSTEM | NUCLEOTIDE POLYMORPHISM ANALYSIS | PANCREATIC ENDOCRINE TUMORS | SOMATOSTATIN ANALOG | ALLELIC ALTERATIONS | PROGNOSTIC-FACTORS | PROGRESSION-FREE SURVIVAL | PHASE-II | OCTREOTIDE LAR | ONCOLOGY | Neuroendocrine Tumors - pathology | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | United States | Humans | National Cancer Institute (U.S.) | Male | Treatment Outcome | Forecasting | Randomized Controlled Trials as Topic | Clinical Trials, Phase III as Topic | Neuroendocrine Tumors - mortality | Survival Analysis | Neuroendocrine Tumors - drug therapy | Female | Practice Guidelines as Topic | Endo2 | Rare | Special | Bios4 | Bios3 | Endo7 | Endo5 | Medical and Health Sciences | MEDICINE | Medicin och hälsovetenskap | MEDICIN
METASTATIC CARCINOID-TUMORS | GRADING SYSTEM | NUCLEOTIDE POLYMORPHISM ANALYSIS | PANCREATIC ENDOCRINE TUMORS | SOMATOSTATIN ANALOG | ALLELIC ALTERATIONS | PROGNOSTIC-FACTORS | PROGRESSION-FREE SURVIVAL | PHASE-II | OCTREOTIDE LAR | ONCOLOGY | Neuroendocrine Tumors - pathology | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | United States | Humans | National Cancer Institute (U.S.) | Male | Treatment Outcome | Forecasting | Randomized Controlled Trials as Topic | Clinical Trials, Phase III as Topic | Neuroendocrine Tumors - mortality | Survival Analysis | Neuroendocrine Tumors - drug therapy | Female | Practice Guidelines as Topic | Endo2 | Rare | Special | Bios4 | Bios3 | Endo7 | Endo5 | Medical and Health Sciences | MEDICINE | Medicin och hälsovetenskap | MEDICIN
Journal Article
Endocrinology and Metabolism Clinics of North America, ISSN 0889-8529, 09/2018, Volume 47, Issue 3, pp. 603 - 614
The role of chemotherapy in neuroendocrine tumors (NETs) has evolved with the development of other effective systemic therapies. At the same time, the evolving...
Chemotherapy | Metastatic | Neuroendocrine tumors | STREPTOZOCIN PLUS FLUOROURACIL | ENETS CONSENSUS GUIDELINES | DOXORUBICIN | ADVANCED CARCINOID-TUMORS | TEMOZOLOMIDE | CELL LUNG-CANCER | PHASE-III TRIAL | CAPECITABINE | HIGH-GRADE | CISPLATIN | ENDOCRINOLOGY & METABOLISM | Neuroendocrine Tumors - drug therapy | Neuroendocrine Tumors - surgery | Antineoplastic Agents - therapeutic use | Chemotherapy, Adjuvant | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Humans
Chemotherapy | Metastatic | Neuroendocrine tumors | STREPTOZOCIN PLUS FLUOROURACIL | ENETS CONSENSUS GUIDELINES | DOXORUBICIN | ADVANCED CARCINOID-TUMORS | TEMOZOLOMIDE | CELL LUNG-CANCER | PHASE-III TRIAL | CAPECITABINE | HIGH-GRADE | CISPLATIN | ENDOCRINOLOGY & METABOLISM | Neuroendocrine Tumors - drug therapy | Neuroendocrine Tumors - surgery | Antineoplastic Agents - therapeutic use | Chemotherapy, Adjuvant | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Humans
Journal Article
Peptides, ISSN 0196-9781, 11/2011, Volume 32, Issue 11, pp. 2340 - 2347
► We examine ghrelin expression in neuroendocrine tumors (NETs). ► We review ghrelin's expression in NETs patients with carcinoids, type A chronic atrophic...
Cancer cachexia | Orexigenic | Endogenous | Ghrelin | Metastatic neuroendocrine tumors | SOMATOSTATIN ANALOGS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GASTROINTESTINAL-TRACT | ENDOCRINE TUMORS | CHROMOGRANIN-A | DES-ACYL GHRELIN | AGOUTI-RELATED PROTEIN | GROWTH-HORMONE SECRETAGOGUE | MESSENGER-RNA | CARCINOID-TUMORS | PHARMACOLOGY & PHARMACY | HELICOBACTER-PYLORI | Immunohistochemistry | Body Weight | Central Nervous System - metabolism | Humans | Gene Expression Regulation, Neoplastic | Male | Carcinoid Tumor - blood | Gastric Mucosa - metabolism | Gastritis, Atrophic - blood | Ghrelin - biosynthesis | Receptors, Ghrelin - genetics | Liver Neoplasms - blood | Gastrointestinal Neoplasms - pathology | In Situ Hybridization | Gastrointestinal Neoplasms - blood | Polymerase Chain Reaction | Receptors, Ghrelin - metabolism | Liver Neoplasms - secondary | Gastritis, Atrophic - pathology | Acylation | Ghrelin - genetics | Carcinoid Tumor - pathology | Ghrelin - metabolism | Multiple Endocrine Neoplasia Type 1 - pathology | Multiple Endocrine Neoplasia Type 1 - blood | Appetite Regulation - physiology | Chronic Disease | Peptides | Liver cancer | Metastasis
Cancer cachexia | Orexigenic | Endogenous | Ghrelin | Metastatic neuroendocrine tumors | SOMATOSTATIN ANALOGS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GASTROINTESTINAL-TRACT | ENDOCRINE TUMORS | CHROMOGRANIN-A | DES-ACYL GHRELIN | AGOUTI-RELATED PROTEIN | GROWTH-HORMONE SECRETAGOGUE | MESSENGER-RNA | CARCINOID-TUMORS | PHARMACOLOGY & PHARMACY | HELICOBACTER-PYLORI | Immunohistochemistry | Body Weight | Central Nervous System - metabolism | Humans | Gene Expression Regulation, Neoplastic | Male | Carcinoid Tumor - blood | Gastric Mucosa - metabolism | Gastritis, Atrophic - blood | Ghrelin - biosynthesis | Receptors, Ghrelin - genetics | Liver Neoplasms - blood | Gastrointestinal Neoplasms - pathology | In Situ Hybridization | Gastrointestinal Neoplasms - blood | Polymerase Chain Reaction | Receptors, Ghrelin - metabolism | Liver Neoplasms - secondary | Gastritis, Atrophic - pathology | Acylation | Ghrelin - genetics | Carcinoid Tumor - pathology | Ghrelin - metabolism | Multiple Endocrine Neoplasia Type 1 - pathology | Multiple Endocrine Neoplasia Type 1 - blood | Appetite Regulation - physiology | Chronic Disease | Peptides | Liver cancer | Metastasis
Journal Article
9.
Full Text
Gastrointestinal neuroendocrine tumors (NETs): new diagnostic and therapeutic challenges
Cancer and Metastasis Reviews, ISSN 0167-7659, 3/2014, Volume 33, Issue 1, pp. 353 - 359
This paper summarizes the current understanding of the biology of somatostatin receptor (sst), role of immunotherapy in neuroendocrine tumor (NET), new agents...
RECIST, SWOG, WHO criteria | Somatostatin receptor | Splicing | GIPR | Oncology | Interferon (IFN) | Biomedicine general | sst5TMD4 | Biomedicine | Incretin receptor (GLP-1R | Cancer Research | Somatostatin | Functional NET imaging | PET | Peptide receptor radionucleotide therapy (PRRT) | Incretin receptor (GLP-1R; GIPR) | SURVIVAL | SOMATOSTATIN ANALOGS | RESPONSE CRITERIA | INTERFERON-ALPHA | PITUITARY-TUMORS | ONCOLOGY | MIDGUT CARCINOID-TUMORS | METASTATIC BREAST-CANCER | GASTROENTEROPANCREATIC TUMORS | LEUKOCYTE INTERFERON | RECEPTOR SUBTYPE 5 | Immunotherapy - methods | Reproducibility of Results | Somatostatin - analogs & derivatives | Neuroendocrine Tumors - metabolism | Humans | Treatment Outcome | Neuroendocrine Tumors - diagnosis | Gastrointestinal Neoplasms - diagnosis | Gastrointestinal Neoplasms - therapy | Diagnostic Imaging - methods | Sensitivity and Specificity | Neuroendocrine Tumors - therapy | Receptors, Somatostatin - metabolism | Somatostatin - therapeutic use | Gastrointestinal Neoplasms - metabolism | Peptides | Immunotherapy | Diagnosis | Biological response modifiers | Health aspects | Cells | Tumors | WHO criteria | RECIST | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Clinical Medicine | SWOG | Cancer and Oncology | Cancer och onkologi
RECIST, SWOG, WHO criteria | Somatostatin receptor | Splicing | GIPR | Oncology | Interferon (IFN) | Biomedicine general | sst5TMD4 | Biomedicine | Incretin receptor (GLP-1R | Cancer Research | Somatostatin | Functional NET imaging | PET | Peptide receptor radionucleotide therapy (PRRT) | Incretin receptor (GLP-1R; GIPR) | SURVIVAL | SOMATOSTATIN ANALOGS | RESPONSE CRITERIA | INTERFERON-ALPHA | PITUITARY-TUMORS | ONCOLOGY | MIDGUT CARCINOID-TUMORS | METASTATIC BREAST-CANCER | GASTROENTEROPANCREATIC TUMORS | LEUKOCYTE INTERFERON | RECEPTOR SUBTYPE 5 | Immunotherapy - methods | Reproducibility of Results | Somatostatin - analogs & derivatives | Neuroendocrine Tumors - metabolism | Humans | Treatment Outcome | Neuroendocrine Tumors - diagnosis | Gastrointestinal Neoplasms - diagnosis | Gastrointestinal Neoplasms - therapy | Diagnostic Imaging - methods | Sensitivity and Specificity | Neuroendocrine Tumors - therapy | Receptors, Somatostatin - metabolism | Somatostatin - therapeutic use | Gastrointestinal Neoplasms - metabolism | Peptides | Immunotherapy | Diagnosis | Biological response modifiers | Health aspects | Cells | Tumors | WHO criteria | RECIST | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Clinical Medicine | SWOG | Cancer and Oncology | Cancer och onkologi
Journal Article
Surgical Clinics of North America, ISSN 0039-6109, 06/2013, Volume 93, Issue 3, pp. 675 - 691
Pancreatic neuroendocrine tumors account for 1% to 2% of pancreatic neoplasms and may occur sporadically or as part of a hereditary syndrome. Patients may...
Pancreatic neuroendocrine tumors | Chemotherapy | Metastatic neuroendocrine tumors | Targeted therapy | Surgery | LONG-TERM SURVIVAL | HEPATIC ARTERIAL CHEMOEMBOLIZATION | ENDOCRINE TUMORS | PHASE-II | CHROMOGRANIN-A | SURGICAL-TREATMENT | LIVER METASTASES | CONSENSUS GUIDELINES | LOW-GRADE | RADIOFREQUENCY ABLATION | Neuroendocrine Tumors - pathology | Liver Transplantation | Pancreatic Neoplasms - diagnosis | Humans | Pancreatic Neoplasms - pathology | Pancreatectomy | Ablation Techniques | Combined Modality Therapy | Liver Neoplasms - therapy | Neuroendocrine Tumors - diagnosis | Embolization, Therapeutic | Pancreaticoduodenectomy | Hepatectomy | Neuroendocrine Tumors - secondary | Neuroendocrine Tumors - therapy | Liver Neoplasms - secondary | Neoplasm Staging | Pancreatic Neoplasms - therapy
Pancreatic neuroendocrine tumors | Chemotherapy | Metastatic neuroendocrine tumors | Targeted therapy | Surgery | LONG-TERM SURVIVAL | HEPATIC ARTERIAL CHEMOEMBOLIZATION | ENDOCRINE TUMORS | PHASE-II | CHROMOGRANIN-A | SURGICAL-TREATMENT | LIVER METASTASES | CONSENSUS GUIDELINES | LOW-GRADE | RADIOFREQUENCY ABLATION | Neuroendocrine Tumors - pathology | Liver Transplantation | Pancreatic Neoplasms - diagnosis | Humans | Pancreatic Neoplasms - pathology | Pancreatectomy | Ablation Techniques | Combined Modality Therapy | Liver Neoplasms - therapy | Neuroendocrine Tumors - diagnosis | Embolization, Therapeutic | Pancreaticoduodenectomy | Hepatectomy | Neuroendocrine Tumors - secondary | Neuroendocrine Tumors - therapy | Liver Neoplasms - secondary | Neoplasm Staging | Pancreatic Neoplasms - therapy
Journal Article
Journal of Hepato‐Biliary‐Pancreatic Sciences, ISSN 1868-6974, 08/2015, Volume 22, Issue 8, pp. 578 - 585
Pancreatic neuroendocrine tumors (PNETs), also known as islet cell tumors, are rare neoplasms that arise in the endocrine tissues of the pancreas. Most of...
Pancreatic neuroendocrine tumors | Metastatic | Functioning | SURGERY | DIAGNOSIS | WATERY DIARRHEA | MANAGEMENT | ISLET CELL TUMOR | ZOLLINGER-ELLISON-SYNDROME | ENDOCRINE NEOPLASIA TYPE-1 | SURGICAL-TREATMENT | GLUCAGONOMA SYNDROME | HYPOGLYCEMIA | EXPERIENCE | GASTROENTEROLOGY & HEPATOLOGY | Neuroendocrine Tumors | Adenoma, Islet Cell | Proteoglycans | Humans | Zollinger-Ellison Syndrome | Vipoma | Pancreatic Neoplasms | Somatostatinoma
Pancreatic neuroendocrine tumors | Metastatic | Functioning | SURGERY | DIAGNOSIS | WATERY DIARRHEA | MANAGEMENT | ISLET CELL TUMOR | ZOLLINGER-ELLISON-SYNDROME | ENDOCRINE NEOPLASIA TYPE-1 | SURGICAL-TREATMENT | GLUCAGONOMA SYNDROME | HYPOGLYCEMIA | EXPERIENCE | GASTROENTEROLOGY & HEPATOLOGY | Neuroendocrine Tumors | Adenoma, Islet Cell | Proteoglycans | Humans | Zollinger-Ellison Syndrome | Vipoma | Pancreatic Neoplasms | Somatostatinoma
Journal Article
Seminars in Liver Disease, ISSN 0272-8087, 11/2018, Volume 38, Issue 4, pp. 351 - 356
Abstract Neuroendocrine tumors are slow-growing tumors and associated with prolonged overall survival even in the presence of untreated liver metastases. The...
Review Article | liver metastases | liver transplantation | neuroendocrine tumors | SURVIVAL | PROGNOSTIC-FACTORS | RESECTION | DEBULKING | OUTCOMES | GASTROENTEROLOGY & HEPATOLOGY | METASTATIC ENDOCRINE TUMORS | Liver Transplantation | Outcome Assessment (Health Care) | Humans | Neoplasm Recurrence, Local | Carcinoma, Hepatocellular - surgery | Liver Neoplasms - surgery | Palliative Care | Carcinoma, Hepatocellular - secondary | Liver Neoplasms - mortality | Transplant Recipients | Hepatectomy | Disease-Free Survival | Quality of Life | Neuroendocrine Tumors - surgery | Liver Neoplasms - secondary
Review Article | liver metastases | liver transplantation | neuroendocrine tumors | SURVIVAL | PROGNOSTIC-FACTORS | RESECTION | DEBULKING | OUTCOMES | GASTROENTEROLOGY & HEPATOLOGY | METASTATIC ENDOCRINE TUMORS | Liver Transplantation | Outcome Assessment (Health Care) | Humans | Neoplasm Recurrence, Local | Carcinoma, Hepatocellular - surgery | Liver Neoplasms - surgery | Palliative Care | Carcinoma, Hepatocellular - secondary | Liver Neoplasms - mortality | Transplant Recipients | Hepatectomy | Disease-Free Survival | Quality of Life | Neuroendocrine Tumors - surgery | Liver Neoplasms - secondary
Journal Article
European Journal of Cancer, ISSN 0959-8049, 2014, Volume 50, Issue 5, pp. 902 - 911
Abstract Background Cytotoxic chemotherapy is widely used for advanced, unresectable pancreatic and other gastrointestinal foregut neuroendocrine tumours...
Hematology, Oncology and Palliative Medicine | Chemotherapy | Neuroendocrine tumour | Randomised clinical trial | Capecitabine | Streptozocin | Phase II | Cisplatin | ISLET-CELL CARCINOMA | PHASE-III | DOXORUBICIN | OXALIPLATIN | METASTATIC COLORECTAL-CANCER | TEMOZOLOMIDE | 5-FLUOROURACIL | ONCOLOGY | PANCREATIC ENDOCRINE CARCINOMAS | PLUS FLUOROURACIL | Gastrointestinal Neoplasms - drug therapy | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Fatigue - chemically induced | Diarrhea - chemically induced | Cisplatin - administration & dosage | Pancreatic Neoplasms - drug therapy | Fluorouracil - administration & dosage | Fluorouracil - adverse effects | Aged, 80 and over | Adult | Deoxycytidine - adverse effects | Female | Surveys and Questionnaires | Streptozocin - adverse effects | Drug Administration Schedule | Fluorouracil - analogs & derivatives | Deoxycytidine - administration & dosage | Anemia - chemically induced | Treatment Outcome | Streptozocin - administration & dosage | Disease-Free Survival | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Cisplatin - adverse effects | Neuroendocrine Tumors - drug therapy | Quality of Life | Aged | Deoxycytidine - analogs & derivatives | Tumors
Hematology, Oncology and Palliative Medicine | Chemotherapy | Neuroendocrine tumour | Randomised clinical trial | Capecitabine | Streptozocin | Phase II | Cisplatin | ISLET-CELL CARCINOMA | PHASE-III | DOXORUBICIN | OXALIPLATIN | METASTATIC COLORECTAL-CANCER | TEMOZOLOMIDE | 5-FLUOROURACIL | ONCOLOGY | PANCREATIC ENDOCRINE CARCINOMAS | PLUS FLUOROURACIL | Gastrointestinal Neoplasms - drug therapy | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Fatigue - chemically induced | Diarrhea - chemically induced | Cisplatin - administration & dosage | Pancreatic Neoplasms - drug therapy | Fluorouracil - administration & dosage | Fluorouracil - adverse effects | Aged, 80 and over | Adult | Deoxycytidine - adverse effects | Female | Surveys and Questionnaires | Streptozocin - adverse effects | Drug Administration Schedule | Fluorouracil - analogs & derivatives | Deoxycytidine - administration & dosage | Anemia - chemically induced | Treatment Outcome | Streptozocin - administration & dosage | Disease-Free Survival | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Cisplatin - adverse effects | Neuroendocrine Tumors - drug therapy | Quality of Life | Aged | Deoxycytidine - analogs & derivatives | Tumors
Journal Article
Endocrine-Related Cancer, ISSN 1351-0088, 03/2018, Volume 25, Issue 3, pp. R115 - R130
Small intestinal neuroendocrine tumours (SI-NETs) are neoplasms characterized by their ability to secrete biogenic amines and peptides. These cause distinct...
Neuroendocrine tumour | Targeted therapy | Growth factors | Tumour microenvironment | Fibrosis | METASTATIC CARCINOID-TUMOR | targeted therapy | neuroendocrine tumour | SIGNALING PATHWAYS | growth factors | STELLATE CELLS | FACTOR-ALPHA | TAMOXIFEN THERAPY | EPITHELIAL-MESENCHYMAL TRANSITION | GROWTH-FACTOR RECEPTOR | SEROTONIN SYNTHESIS | ONCOLOGY | ENDOCRINOLOGY & METABOLISM | CONSENSUS GUIDELINES UPDATE | fibrosis | tumour microenvironment | SUBSTANCE-P | Mesentery - metabolism | Neuroendocrine Tumors - pathology | Intestine, Small - pathology | Neuroendocrine Tumors - metabolism | Humans | Intestinal Neoplasms - metabolism | Tumor Microenvironment | Intestinal Neoplasms - pathology | Animals | Mesentery - pathology | Neuroendocrine Tumors - drug therapy | Intestine, Small - metabolism | Intestinal Neoplasms - drug therapy
Neuroendocrine tumour | Targeted therapy | Growth factors | Tumour microenvironment | Fibrosis | METASTATIC CARCINOID-TUMOR | targeted therapy | neuroendocrine tumour | SIGNALING PATHWAYS | growth factors | STELLATE CELLS | FACTOR-ALPHA | TAMOXIFEN THERAPY | EPITHELIAL-MESENCHYMAL TRANSITION | GROWTH-FACTOR RECEPTOR | SEROTONIN SYNTHESIS | ONCOLOGY | ENDOCRINOLOGY & METABOLISM | CONSENSUS GUIDELINES UPDATE | fibrosis | tumour microenvironment | SUBSTANCE-P | Mesentery - metabolism | Neuroendocrine Tumors - pathology | Intestine, Small - pathology | Neuroendocrine Tumors - metabolism | Humans | Intestinal Neoplasms - metabolism | Tumor Microenvironment | Intestinal Neoplasms - pathology | Animals | Mesentery - pathology | Neuroendocrine Tumors - drug therapy | Intestine, Small - metabolism | Intestinal Neoplasms - drug therapy
Journal Article