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Neuro-oncology (Charlottesville, Va.), ISSN 1523-5866, 2013, Volume 15, Issue 1, pp. 4 - 27
Journal Article
Experimental cell research, ISSN 0014-4827, 05/2016, Volume 343, Issue 2, pp. 148 - 158
The aim of this study was to investigate the effect of downregulation of HIF-1α gene on human U251 glioma cells and examine the consequent changes of TMZ... 
Notch1 pathway | Brain glioma | O6-methylguanine DNA methyltransferase (MGMT) | HIF-1α | Temozolomide | Drug resistance | methylguanine DNA methyltransferase (MGMT) | O-6-methylguanine DNA methyltransferase (MGMT) | HIF-1 alpha | STABILITY | MGMT EXPRESSION | HYDROXYLATION | NOTCH | HYPOXIA | CANCER STEM-CELLS | CELL BIOLOGY | ONCOLOGY | RESISTANCE | HIF-1-ALPHA | CONTRIBUTES | GLIOBLASTOMA CELLS | Apoptosis - drug effects | Dacarbazine - therapeutic use | Humans | Brain Neoplasms - pathology | Neoplasm Proteins - metabolism | Glioma - genetics | Transfection | Dacarbazine - pharmacology | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Glioma - pathology | Dacarbazine - analogs & derivatives | Gene Expression Regulation, Neoplastic - drug effects | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Neoplasm Invasiveness | Brain Neoplasms - genetics | Brain Neoplasms - drug therapy | Down-Regulation - drug effects | Down-Regulation - genetics | Cell Movement - drug effects | Signal Transduction - drug effects | Cell Differentiation - drug effects | Cell Line, Tumor | Cell Proliferation - drug effects | Glioma - drug therapy | RNA, Small Interfering - metabolism | Antimitotic agents | Nervous system diseases | Antineoplastic agents | Gliomas | Brain tumors | Transferases | Studies | Cellular biology | Genes | Deoxyribonucleic acid--DNA | APOPTOSIS | DMSO | BLOOD-BRAIN BARRIER | 60 APPLIED LIFE SCIENCES | BROMIDES | TETRAZOLIUM | SKELETON | REPAIR | POLYMERASE CHAIN REACTION | MESSENGER-RNA | ESTERS | GENES | GUANINE | BRAIN | BLOOD | GLIOMAS | GLYCINE | COLONY FORMATION | CELL PROLIFERATION | HEALING | ANOXIA | DNA | WOUNDS | STEM CELLS | MAGNESIUM OXIDES
Journal Article
Acta neuropathologica, ISSN 1432-0533, 2018, Volume 135, Issue 4, pp. 601 - 615
textabstractThe optimal treatment for patients with low-grade glioma (LGG) WHO grade II remains controversial. Overall survival ranges from 2 to over 15 years... 
TMZ | DNA methylation | DDR genes | MGMT-STP27 | Randomized trial | Low-grade glioma | Pathology | Neurosciences | Medicine & Public Health | CELLS | METHYLATION | MGMT | SENSITIVITY | MISMATCH REPAIR | PATHOLOGY | TUMORS | NEUROSCIENCES | CLINICAL NEUROLOGY | TEMOZOLOMIDE | GLIOBLASTOMA | RADIOTHERAPY | EXPRESSION | Epigenesis, Genetic | Humans | Brain Neoplasms - pathology | DNA Repair Enzymes - genetics | Male | Glioma - genetics | Temozolomide - therapeutic use | Neoplasm Grading | DNA Methylation - radiation effects | Glioma - pathology | Tumor Suppressor Proteins - genetics | Glioma - therapy | Adult | Female | Promoter Regions, Genetic | Discoidin Domain Receptors - genetics | Brain Neoplasms - genetics | Isocitrate Dehydrogenase - genetics | Treatment Outcome | Antineoplastic Agents, Alkylating - therapeutic use | DNA Modification Methylases - genetics | DNA | Progression-Free Survival | Brain Neoplasms - therapy | CpG Islands | DNA Methylation - drug effects | Medical colleges | Medical research | Care and treatment | DNA damage | Genes | Medicine, Experimental | Genetic aspects | Radiotherapy | Methylation | Cancer | Preservation | Brain tumors | Genotoxicity | Cognitive ability | Genomes | Radiation therapy | Survival | Quality of life | Glioma | Temozolomide | Isocitrate dehydrogenase | Deoxyribonucleic acid--DNA | CpG islands | Original Paper
Journal Article
Journal Article
Immunologic Research, ISSN 0257-277X, 7/2009, Volume 44, Issue 1, pp. 112 - 126
Current approaches for hematopoietic stem cell (HSC) and organ transplantation are limited by donor and host-mediated immune responses to allo-antigens.... 
Major histocompatibility complex (MHC) | O 6 -methylguanine-DNA-methyltransferase (MGMT) | Internal Medicine | Human leukocyte antigen (HLA) | Medicine/Public Health, general | Lentivirus | Allergology | Busulfan (BU) | RNA interference (RNAi) | MGMT P140K -2A-GFP lentivirus vector (MAG) | Immunology | 1,3-bis(2-chloroethyl)-1-nitroso-urea (BCNU) | Medicine & Public Health | Benzylguanine (BG) | Short hairpin-type RNAi (shRNA) | MGMT | 2A-GFP lentivirus vector (MAG) | methylguanine- DNA-methyltransferase (MGMT) | UNRELATED DONOR | O-6-methylguanine-DNA-methyltransferase (MGMT) | CHEMOPROTECTION | TRANSDUCTION | IMMUNOLOGY | LARGE-ANIMAL MODEL | THERAPY | BONE-MARROW TRANSPLANTATION | MGMT(P140K)-2A-GFP lentivirus vector (MAG) | SELECTION | DRUG-RESISTANCE GENE | RETROVIRAL VECTOR | LYMPHOCYTES | Hematopoietic Stem Cells - drug effects | Gene Transfer Techniques | RNA, Small Interfering - genetics | DNA Modification Methylases - metabolism | Humans | Gene Silencing | Histocompatibility Antigens Class I - immunology | Histocompatibility Antigens Class I - genetics | Carmustine - pharmacology | Gene Knockdown Techniques | Hematopoietic Stem Cells - immunology | Animals | Transfection | Mice | Hematopoietic Stem Cell Transplantation - methods | Genetic Vectors | Immunohistochemistry | Leucocytes | Transplants & implants | Ribonucleic acid--RNA | Stem cells | Index Medicus | RNAi – RNA interference | MAG - MGMTP140K-2A-GFP lentivirus vector | MGMT - O6-methylguanine-DNA-methyltransferase | BU - Busulfan | BG - Benzylguanine | BCNU - 1,3-bis(2-chloroethyl1-nitrosourea) | MHC – Major Histocompability Complex | shRNA - short hairpin-type RNAi | HLA – Human Leukocyte Antigen
Journal Article
Biochimica et biophysica acta. Reviews on cancer, ISSN 0304-419X, 08/2012, Volume 1826, Issue 1, pp. 71 - 82
Gliomas are the most frequent adult primary brain tumor, and are invariably fatal. The most common diagnosis glioblastoma multiforme (GBM) afflicts 12,500 new... 
Biomarker | Chemotherapy resistance | Glioma | MGMT | Alkylating agents | Glioblastoma
Journal Article