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microembolization (224) 224
cardiac & cardiovascular systems (174) 174
index medicus (167) 167
animals (163) 163
male (154) 154
coronary microembolization (153) 153
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tnf-alpha (49) 49
inflammation (45) 45
stents (44) 44
physiology (42) 42
medicine & public health (41) 41
rats (41) 41
infarction (40) 40
heart-failure (39) 39
treatment outcome (39) 39
dysfunction (38) 38
microspheres (38) 38
endarterectomy (37) 37
myocardial infarction (37) 37
myocardium - pathology (37) 37
heart (36) 36
myocardium - metabolism (35) 35
necrosis-factor-alpha (34) 34
time factors (34) 34
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analysis (30) 30
cell biology (30) 30
risk factors (30) 30
stroke (28) 28
acute myocardial-infarction (26) 26
expression (26) 26
injury (26) 26
microcirculation (25) 25
nitric-oxide (25) 25
reperfusion (25) 25
aged, 80 and over (24) 24
disease (24) 24
intervention (24) 24
mice (24) 24
microvascular obstruction (24) 24
myocardial infarction - pathology (24) 24
tumor-necrosis-factor (24) 24
coronary circulation (23) 23
embolism - pathology (23) 23
embolization (23) 23
pharmacology & pharmacy (23) 23
abridged index medicus (22) 22
adenosine (22) 22
myocardial infarction - physiopathology (22) 22
perfusion (22) 22
radiology, nuclear medicine & medical imaging (22) 22
stent (22) 22
echocardiography (21) 21
embolism - physiopathology (21) 21
no-reflow phenomenon (21) 21
tumor necrosis factor-alpha - metabolism (21) 21
blood-flow (20) 20
cardiovascular (20) 20
embolism - etiology (20) 20
cardioprotection (19) 19
carotid stenosis - therapy (19) 19
cerebral protection (19) 19
magnetic resonance imaging (19) 19
myocardial-infarction (19) 19
rats, sprague-dawley (19) 19
hemodynamics (18) 18
prospective studies (18) 18
risk (18) 18
stenosis (18) 18
adult (17) 17
mortality (17) 17
oxidative stress (17) 17
protection (17) 17
research (17) 17
cardiomyocytes (16) 16
carotid artery stenting (16) 16
medicine, research & experimental (16) 16
swine, miniature (16) 16
unstable angina (16) 16
apoptosis - drug effects (15) 15
hematology (15) 15
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1. Purtscher-like retinopathy after placental abruption
by Connery, Sheila A
Journal of Reproductive Medicine, ISSN 0024-7758, 02/2017, Volume 62, Issue 1, pp. 79 - 81
BACKGROUND: Pregnant women are susceptible to visual disturbances, particularly with hypertension. Vision generally recovers postpartum within hours to days. A... 
Vasculopathy | Microembolization | Retinopathy
Journal Article
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2. Purtscher-like Retinopathy After Placental Abruption A Case Report
by Connery, SA
JOURNAL OF REPRODUCTIVE MEDICINE, ISSN 0024-7758, 01/2017, Volume 62, Issue 1-2, pp. 79 - 81
BACKGROUND: Pregnant women are susceptible to visual disturbances, particularly with hypertension. Vision generally recovers postpartum within hours to days. A... 
retinopathy | vasculopathy | microembolization | OBSTETRICS & GYNECOLOGY
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3. Full Text Egr-1 is involved in coronary microembolization-induced myocardial injury via Bim/Beclin-1 pathway-mediated autophagy inhibition and apoptosis activation
by Wang, Xian-tao and Wu, Xiao-dan and Lu, Yuan-xi and Sun, Yu-han and Zhu, Han-hua and Liang, Jia-bao and He, Wen-kai and Li, Lang
Aging, ISSN 1945-4589, 11/2018, Volume 10, Issue 11, pp. 3136 - 3147
Coronary microembolization (CME) substantially reduces the clinical benefits of myocardial reperfusion therapy. Autophagy and apoptosis participate in the... 
Egr-1 | Coronary microembolization | Autophagy | Apoptosis | Myocardial injury
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4. Full Text Effects of nicorandil on PI3K/Akt signaling pathway and its antiapoptotic mechanisms in coronary microembolization in rats
by Su, Qiang and Li, Lang and Zhao, Jinmin and Sun, Yuhan and Yang, Huafeng
Oncotarget, 2017, Volume 8, Issue 59, pp. 99347 - 99358
Coronary microembolization | Nicorandil | Apoptosis | Myocardial injury | PI3K/Akt
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5. Full Text Risk factors associated with microembolization after carotid intervention
by Sabat, Joseph, MD, PhD and Bock, Diane, BS and Hsu, Chiu-Hsieh, PhD and Tan, Tze-Woei, MD and Weinkauf, Craig, MD, PhD and Trouard, Theodore, PhD and Perez-Carrillo, Gloria Guzman, MD and Zhou, Wei, MD
Journal of Vascular Surgery, ISSN 0741-5214, 2019
AbstractBackgroundMicroembolization after carotid artery stenting (CAS) and carotid endarterectomy (CEA) has been documented and may confer risk for... 
Surgery
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6. Full Text Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injury
by Kawaguchi, Masanori and Takahashi, Masafumi and Hata, Takeki and Kashima, Yuichiro and Usui, Fumitake and Morimoto, Hajime and Izawa, Atsushi and Takahashi, Yasuko and Masumoto, Junya and Koyama, Jun and Hongo, Minoru and Noda, Tetsuo and Nakayama, Jun and Sagara, Junji and Taniguchi, Shun'Ichiro and Ikeda, Uichi
Circulation, ISSN 0009-7322, 02/2011, Volume 123, Issue 6, pp. 594 - 604
Background-Inflammation plays a key role in the pathophysiology of myocardial ischemia/reperfusion (I/R) injury; however, the mechanism by which myocardial I/R... 
cytokine | hypoxia | inflammation | heart | leukocyte | APOPTOSIS | CELLS | CARDIAC & CARDIOVASCULAR SYSTEMS | SPECK-LIKE PROTEIN | CONTRACTILE DYSFUNCTION | CORONARY MICROEMBOLIZATION | NALP3 INFLAMMASOME | ASC | INFARCTION | PERIPHERAL VASCULAR DISEASE | MICE | Potassium - metabolism | Inflammasomes - metabolism | Reactive Oxygen Species - metabolism | Humans | Mice, Inbred C57BL | Middle Aged | Caspase 1 - metabolism | Male | Myocardial Infarction - metabolism | Myocardial Reperfusion Injury - metabolism | Inflammation - metabolism | Animals | Myocardium - metabolism | Myocytes, Cardiac - metabolism | Interleukin-1beta - biosynthesis | Mice | Cytokines - biosynthesis | Fibroblasts - metabolism | Mediators | Physiological aspects | Myocardial ischemia | Development and progression | Inflammation | Research | Reperfusion injury
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7. Full Text The PROFI study (Prevention of cerebral embolization by proximal balloon occlusion compared to filter protection during carotid artery stenting): A prospective randomized trial
by Bijuklic, Klaudija and Wandler, Andreas and Hazizi, Fadia and Schofer, Joachim
Journal of the American College of Cardiology, ISSN 0735-1097, 04/2012, Volume 59, Issue 15, pp. 1383 - 1389
Objectives: The objective of this study was to compare the cerebral embolic load of filter-protected versus proximal balloonprotected carotid artery stenting... 
carotid artery stenting | diffusion-weighted magnetic resonance imaging | cerebral embolic protection | DIFFUSION-WEIGHTED MRI | CARDIAC & CARDIOVASCULAR SYSTEMS | EMBOLIC PROTECTION | ISCHEMIA | ENDARTERECTOMY | MICROEMBOLIZATION | STROKE | ANGIOPLASTY | HIGH-RISK | DEVICES | UPDATE | Prospective Studies | Follow-Up Studies | Humans | Male | Treatment Outcome | Intracranial Embolism - epidemiology | Carotid Stenosis - complications | Balloon Occlusion - methods | Incidence | Intraoperative Complications | Carotid Stenosis - diagnosis | Intraoperative Care - methods | Diffusion Magnetic Resonance Imaging | Aged, 80 and over | Female | Aged | Intracranial Embolism - prevention & control | Intracranial Embolism - etiology | Stents | Carotid Stenosis - surgery
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8. Full Text Divergent tumor necrosis factor receptor-related remodeling responses in heart failure:Role of nuclear factor-κB and inflammatory activation
by Hamid, Tariq and Gu, Yan and Ortines, Roger V and Bhattacharya, Chhandashri and Wang, Guangwu and Xuan, Yu-Ting and Prabhu, Sumanth D
Circulation, ISSN 0009-7322, 03/2009, Volume 119, Issue 10, pp. 1386 - 1397
Background - Although preclinical data suggested that tumor necrosis factor-alpha (TNF) neutralization in heart failure (HF) would be beneficial, clinical... 
Heart failure | Inflammation | Remodeling | Tumor necrosis factor | CARDIAC-FUNCTION | PATHWAYS | heart failure | remodeling | OXIDATIVE STRESS | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | CORONARY MICROEMBOLIZATION | FACTOR-ALPHA | MURINE MODEL | INHIBITION | tumor necrosis factor | LEFT-VENTRICULAR DYSFUNCTION | inflammation | PERIPHERAL VASCULAR DISEASE | TNF-ALPHA
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9. Full Text Carotid StentingWithout Protection: When is it Worth the Risk?
by Levy, EI
NEUROSURGERY, ISSN 0148-396X, 01/2017, Volume 80, Issue 1, pp. 65 - 65
SURGERY | DISTAL | DEVICE | RANDOMIZED-TRIAL | PROXIMAL CEREBRAL PROTECTION | CLINICAL NEUROLOGY | MICROEMBOLIZATION
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10. Full Text Cardioprotection: Nitric oxide, protein kinases, and mitochondria
by Keusch, Gerd and Boengler, Kerstin and Schulz, Rainer
Circulation, ISSN 0009-7322, 11/2008, Volume 118, Issue 19, pp. 1915 - 1919
Signal transduction | Nitric oxide synthase | Editorials | Reperfusion | Ischemia | Nitric oxide | CARDIAC & CARDIOVASCULAR SYSTEMS | ATP CHANNELS | MYOCARDIAL-INFARCTION | LATE-PHASE | HIBERNATING MYOCARDIUM | NECROSIS-FACTOR-ALPHA | CORONARY MICROEMBOLIZATION | PERMEABILITY TRANSITION | ISCHEMIA-REPERFUSION INJURY | SENSITIVE K+ CHANNEL | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | MOUSE HEARTS | Protein Kinases - metabolism | Myocardial Stunning - metabolism | Animals | Ischemic Preconditioning, Myocardial | Humans | Mitochondria - metabolism | Nitric Oxide - metabolism | Prevention | Mitochondria | Physiological aspects | Research | Protein kinases | Heart attack
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11. The observation of phosphatase and tensin homolog deleted on chromosome ten (PTEN) activation and its dynamic changes following the coronary microembolization
by Wang, Jiangyou and Li, Lang and Su, Qiang and Zhou, You and Ma, Guotian and Liu, Tao and Tang, Zhongli and Liu, Yangchun
Experimental and Clinical Cardiology, ISSN 1205-6626, 2014, Volume 20, Issue 1, pp. 2246 - 2274
Coronary microembolization | Troponin | PTEN | Apoptosis
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12. Full Text Liraglutide attenuates NLRP3 inflammasome-dependent pyroptosis via regulating SIRT1/NOX4/ROS pathway in H9c2 cells
by Chen, Zhangwei and Chen, Ao and Xia, Yan and Lu, Danbo and Yang, Xiangdong and Sun, Aijun and Zou, Yunzeng and Qian, Juying and Ge, Junbo
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 05/2018, Volume 499, Issue 2, pp. 267 - 272
The glucagon-like peptide-1 analog liraglutide has been proved to exert cardioprotective role via activating prosurvival pathways and suppressing inflammation.... 
Pyroptosis | NLRP3 inflammasome | SIRT1 | Liraglutide | H9c2 cells | APOPTOSIS | ACTIVATION | MYOCARDIAL-INFARCTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEART-FAILURE | ACUTE LUNG INJURY | CORONARY MICROEMBOLIZATION | PROTECTS | BIOPHYSICS | DISEASE | MICE | OUTCOMES | Glucagon | Cardiology
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13. Structural, functional and histological features of a novel ischemic heart failure model
by Cui, YC and Luo, FL and Li, B and Jia, LJ and Peng, P and Luo, CL and Wang, X and Tang, Y
FRONTIERS IN BIOSCIENCE-LANDMARK, ISSN 1093-9946, 01/2019, Volume 24, pp. 723 - 734
There is still no satisfactory large-animal model of ischemic heart failure (IHF) with ideal survival rate and model time. The aim of this study is to explore... 
MYOCARDIUM | Chronic Heart Failure | LARGE ANIMAL-MODEL | Animal Model | BIOCHEMISTRY & MOLECULAR BIOLOGY | CARDIOMYOPATHY | SEQUENTIAL CORONARY MICROEMBOLIZATION | OVINE MODEL | Coronary Ligation | Miniature Pig | CELL BIOLOGY
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14. Full Text Aloperine Activates the PI3K/Akt Pathway and Protects Against Coronary Microembolisation-Induced Myocardial Injury in Rats
by Mao, Qing and Guo, Fenfen and Liang, Xiulin and Wu, Yufu and Lu, Yongxiang
Pharmacology, ISSN 0031-7012, 06/2019, Volume 104, Issue 1-2, pp. 90 - 97
Background: Coronary microembolisation (CME)-induced myocardial apoptosis is a key factor in progressive cardiac dysfunction. Aloperine (ALO) plays a... 
Research Article | Coronary microembolisation | Aloperine | Apoptosis | Myocardial injury | PI3K/Akt | CARDIOMYOCYTE APOPTOSIS | SIGNALING PATHWAY | SWINE | PHARMACOLOGY & PHARMACY | NICORANDIL | MICROEMBOLIZATION
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15. Full Text Activation of the protective Survivor Activating Factor Enhancement (SAFE) pathway against reperfusion injury: Does it go beyond the RISK pathway?
by Lecour, Sandrine
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2009, Volume 47, Issue 1, pp. 32 - 40
Abstract Lethal reperfusion injury is now recognized as a major limitation of current reperfusion therapy by primary percutaneous coronary intervention for... 
Cardiovascular | Signal transducer and activator of transcription | Tumor necrosis factor alpha | Ischemia | Protective signaling pathways | Reperfusion injury | PERMEABILITY TRANSITION PORE | CARDIAC & CARDIOVASCULAR SYSTEMS | HEART-FAILURE | MYOCARDIAL ISCHEMIA/REPERFUSION INJURY | CARDIAC MYOCYTE | CORONARY MICROEMBOLIZATION | CELL BIOLOGY | TUMOR-NECROSIS-FACTOR | INDUCED CARDIOPROTECTION | TNF-ALPHA | ISCHEMIA-REPERFUSION | SIGNAL TRANSDUCER | Tumor Necrosis Factor-alpha - metabolism | Myocardial Reperfusion Injury - metabolism | Animals | Models, Biological | Humans | Tumor Necrosis Factor-alpha - physiology | Signal Transduction - physiology | STAT3 Transcription Factor - metabolism
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16. Full Text Lessons from human coronary aspirate
by Kleinbongard, Petra and Konorza, Thomas and Böse, Dirk and Baars, Theodor and Haude, Michael and Erbel, Raimund and Heusch, Gerd
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2011, Volume 52, Issue 4, pp. 890 - 896
Abstract The interventional implantation of a stent into an atherosclerotic coronary artery is a unique and paradigmatic scenario of plaque rupture in humans.... 
Cardiovascular | Coronary microembolization | Plaque rupture | TNFα | Serotonin | No reflow phenomenon | Thromboxane | Protection device | Coronary aspirate | MICROVASCULAR OBSTRUCTION | CARDIAC & CARDIOVASCULAR SYSTEMS | TNF alpha | PERCUTANEOUS INTERVENTION | NO-REFLOW PHENOMENON | EUROPEAN-SOCIETY | MICROEMBOLIZATION | CELL BIOLOGY | STENT IMPLANTATION | TASK-FORCE | THROMBUS ASPIRATION | ACUTE MYOCARDIAL-INFARCTION | DISTAL EMBOLIZATION | Coronary Vessels - pathology | Coronary Artery Disease - therapy | Coronary Artery Disease - physiopathology | Coronary Circulation - physiology | Humans | Coronary Artery Disease - pathology | Stents | Angioplasty, Balloon, Coronary
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17. Full Text Regulatory T cells ameliorate cardiac remodeling after myocardial infarction
by Tang, Ting-Ting and Tang, Ting-Ting and Yuan, Jing and Yuan, Jing and Zhu, Zheng-Feng and Zhu, Zheng-Feng and Zhang, Wen-Cai and Zhang, Wen-Cai and Xiao, Hong and Xiao, Hong and Xia, Ni and Xia, Ni and Yan, Xin-Xin and Yan, Xin-Xin and Nie, Shao-Fang and Nie, Shao-Fang and Liu, Juan and Liu, Juan and Zhou, Su-Feng and Zhou, Su-Feng and Li, Jing-Jing and Li, Jing-Jing and Yao, Rui and Yao, Rui and Liao, Meng-Yang and Liao, Meng-Yang and Tu, Xin and Tu, Xin and Liao, Yu-Hua and Liao, Yu-Hua and Cheng, Xiang and Cheng, Xiang
Basic Research in Cardiology, ISSN 0300-8428, 1/2012, Volume 107, Issue 1, pp. 1 - 17
Persistent inflammatory responses participate in the pathogenesis of adverse ventricular remodeling after myocardial infarction (MI). We hypothesized that... 
Myocardial infarction | Cardiac remodeling | Medicine & Public Health | Cardiology | Regulatory T cells | CD28 superagonists | CARDIAC & CARDIOVASCULAR SYSTEMS | TROPONIN I-AUTOANTIBODIES | CONTRACTILE DYSFUNCTION | HEART-FAILURE | NECROSIS-FACTOR-ALPHA | CORONARY MICROEMBOLIZATION | ISCHEMIC CARDIOMYOPATHY | MICE | TNF-ALPHA | INFLAMMATORY RESPONSE | EXPRESSION | Interleukins | Genetic research | Inflammation | Universities and colleges | T cells | Macrophages | Heart attack
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18. Full Text MicroRNA-486-5p targeting PTEN Protects Against Coronary Microembolization-Induced Cardiomyocyte Apoptosis in Rats by activating the PI3K/AKT pathway
by Zhu, Han-hua and Wang, Xian-tao and Sun, Yu-han and He, Wen-kai and Liang, Jia-bao and Mo, Bing-hai and Li, Lang
European Journal of Pharmacology, ISSN 0014-2999, 07/2019, Volume 855, pp. 244 - 251
Coronary microembolization (CME) is responsible for a substantial fraction of microvascular obstruction (MVO), which are strongly associated with mortality and... 
PTEN | Coronary microembolization | Cardiomyocyte | miR-486 | Apoptosis | MICROVASCULAR OBSTRUCTION | MYOCARDIAL-INFARCTION | SIGNALING PATHWAY | INJURY | NO-REFLOW PHENOMENON | CELL-SIZE | PHARMACOLOGY & PHARMACY | Transluminal angioplasty | Heart | Phosphatases | MicroRNA | Luciferase | Mortality | Genetic research | Cardiology | Health aspects
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19. Full Text Toll-like receptor 4 mediates maladaptive left ventricular remodeling and impairs cardiac function after myocardial infarction
by Timmers, Leo and Sluijter, Joost P. G and van Keulen, J. Karlijn and Hoefer, Imo E and Nederhoff, Marcel G. J and Goumans, Marie-Jose and Doevendans, Pieter A and van Echteld, Cees J. A and Joles, Jaap A and Quax, Paul H and Piek, Jan J and Pasterkamp, Gerard and de kleijn, Dominique P. V
Circulation research, ISSN 0009-7330, 2008, Volume 102, Issue 2, pp. 257 - 264
Left ventricular (LV) remodeling leads to congestive heart failure and is a main determinant of morbidity and mortality following myocardial infarction.... 
Myocardial infarction | Remodeling | Toll-like receptor 4 | remodeling | CARDIAC & CARDIOVASCULAR SYSTEMS | CONTRACTILE DYSFUNCTION | myocardial infarction | HEART-FAILURE | CORONARY MICROEMBOLIZATION | TOLL-LIKE RECEPTOR-4 | FIBRONECTIN | PERIPHERAL VASCULAR DISEASE | TNF-ALPHA | TARGETED DELETION | HEMATOLOGY | MATRIX-METALLOPROTEINASE INHIBITION | EXPRESSION | 4-DEFICIENT MICE | Heart - physiopathology | Stroke Volume | Toll-Like Receptor 4 - physiology | Heart Failure - therapy | Ventricular Remodeling | Animals | Toll-Like Receptor 4 - deficiency | Gene Expression Regulation | Myocardial Infarction - physiopathology | Mice | Cytokines - genetics
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20. Full Text Myocardial ischemia: lack of coronary blood flow, myocardial oxygen supply-demand imbalance, or what?
by Heusch, G
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, ISSN 0363-6135, 06/2019, Volume 316, Issue 6, pp. H1439 - H1446
This opinionated article reviews current concepts of myocardial ischemia. Specifically, the historical background is briefly presented. Then, the prevailing... 
MECHANICAL REPERFUSION | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | myocardial infarction | REGIONAL DYSFUNCTION | hibernation | stunning | EXERCISE | MICROEMBOLIZATION | INFARCT SIZE | HEART | RESERVE | BETA-BLOCKADE | PERIPHERAL VASCULAR DISEASE | myocardial ischemia | coronary blood flow | PERFUSION-PRESSURE | CARDIOPROTECTION | reperfusion
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