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udp-glucuronosyltransferase inducers (26) 26
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cytochrome p-450 enzyme system - metabolism (23) 23
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enzymes (23) 23
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rna, messenger - metabolism (22) 22
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enzyme induction - drug effects (20) 20
polychlorinated biphenyls (20) 20
glucuronidation (19) 19
phenobarbital - pharmacology (19) 19
rat-liver (19) 19
receptors, cytoplasmic and nuclear - metabolism (19) 19
thyroid hormones - metabolism (19) 19
polychlorinated biphenyls - toxicity (18) 18
thyrotropin - blood (18) 18
thyroxine - metabolism (18) 18
glucuronosyltransferase - genetics (17) 17
organ size - drug effects (17) 17
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endocrine disruptors - toxicity (13) 13
gene-expression (13) 13
microsomal enzymes (13) 13
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rodents (13) 13
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cytochrome p-450 (12) 12
cytochrome p-450 enzyme system - biosynthesis (12) 12
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Journal Article
Journal Article
Toxicological Sciences, ISSN 1096-6080, 2014, Volume 138, Issue 2, pp. 425 - 445
Journal Article
Journal Article
Environmental Health Perspectives, ISSN 0091-6765, 10/2007, Volume 115, Issue 10, pp. 1490 - 1496
Background: Studies have reported that prenatal exposure to polychlorinated biphenyls (PCBs) may alter neurodevelopment in both humans and animals.... 
Chemical hazards | Pregnancy | Enzymes | Congeners | Environmental health | Polychlorinated biphenyls | Rats | Thyroid hormones | Blood | Gestational age | Children's Health | Prenatal | Microsomal enzymes | Neonatal | UDP-glucuronosyltransferase | Enzyme inducers | Cytochrome P450 | TSH | Thyroid hormone | In utero | SUBCHRONIC TOXICITY | HUMAN-SERUM | IN-UTERO | in utero | enzyme inducers | thyroid hormone | PSYCHOMOTOR DEVELOPMENT | neonatal | cytochrome P450 | polychlorinated | microsomal enzymes | UDP-GLUCURONOSYLTRANSFERASE INDUCERS | ENVIRONMENTAL SCIENCES | DIETARY EXPOSURE | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | prenatal | ORGANOCHLORINE COMPOUNDS | biphenyls | MICROSOMAL-ENZYME INDUCERS | PERINATAL PCB EXPOSURE | RISK-ASSESSMENT | Mexican Americans | Glucuronosyltransferase - drug effects | Prenatal Exposure Delayed Effects - epidemiology | California - epidemiology | Humans | Middle Aged | Prenatal Exposure Delayed Effects - metabolism | Thyrotropin - drug effects | Environmental Exposure - adverse effects | Cytochrome P-450 Enzyme System - drug effects | Polychlorinated Biphenyls - chemistry | Polychlorinated Biphenyls - toxicity | Adolescent | Prenatal Exposure Delayed Effects - blood | Adult | Female | Polychlorinated Biphenyls - classification | Infant, Newborn | Cohort Studies | Thyrotropin - blood | Evaluation | Prenatal influences | Neonatology | Research | Health aspects | Index Medicus | polychlorinated biphenyls
Journal Article
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 07/2012, Volume 40, Issue 7, pp. 1366 - 1379
The transcription factors aryl hydrocarbon receptor (AhR), constitutive androstane receptor (CAR), pregnane X receptor (PXR), peroxisome proliferator-activated... 
TRANSCRIPTION FACTORS | PRIMARY HUMAN HEPATOCYTES | ANTIOXIDANT RESPONSE ELEMENT | MESSENGER-RNA EXPRESSION | CONSTITUTIVE ANDROSTANE RECEPTOR | BILIARY-EXCRETION | PROLIFERATOR-ACTIVATED RECEPTOR | MOUSE-LIVER | PHARMACOLOGY & PHARMACY | MICROSOMAL-ENZYME INDUCERS | PREGNANE-X-RECEPTOR | Inactivation, Metabolic | Receptors, Steroid - metabolism | Cytochrome P-450 Enzyme System - metabolism | Male | NAD(P)H Dehydrogenase (Quinone) - genetics | Organic Anion Transporters - metabolism | Glucuronosyltransferase - genetics | Organic Anion Transporters - genetics | Glutathione Transferase - genetics | Receptors, Aryl Hydrocarbon - metabolism | Female | NF-E2-Related Factor 2 - genetics | Sulfotransferases - metabolism | Aldehyde Dehydrogenase - metabolism | Sulfotransferases - genetics | Liver - metabolism | Mice, Inbred C57BL | RNA, Messenger - genetics | Receptors, Aryl Hydrocarbon - genetics | Glutathione Transferase - metabolism | Aldehyde Dehydrogenase - genetics | PPAR alpha - genetics | Receptors, Cytoplasmic and Nuclear - genetics | Transcription Factors - genetics | Mice, Knockout | Gene Expression Regulation, Enzymologic | Transcription Factors - metabolism | Animals | Glucuronosyltransferase - metabolism | Receptors, Steroid - genetics | NF-E2-Related Factor 2 - metabolism | Cytochrome P-450 Enzyme System - genetics | NAD(P)H Dehydrogenase (Quinone) - metabolism | Mice | PPAR alpha - metabolism | Multidrug Resistance-Associated Proteins | Receptors, Cytoplasmic and Nuclear - metabolism | Index Medicus
Journal Article
Toxicology, ISSN 0300-483X, 2014, Volume 328, pp. 21 - 28
Abstract Xenobiotics may interfere with the hypothalamic-pituitary-thyroid endocrine axis by inducing enzymes that inactivate thyroid hormones and thereby... 
Emergency | Endocrine disruption | Thyroid hormone | UDP-glucuronosyltransferase | Aryl-hydrocarbon receptor | Cyp2b1 | Xenobesity | ACTIVATION | RAT HEPATOCYTES | GLUCURONIDATION | MOUSE-LIVER | ALPHA | PREGNANE-X-RECEPTOR | NUCLEAR RECEPTOR | UDP-GLUCURONOSYLTRANSFERASES | GLUCURONOSYLTRANSFERASE MESSENGER-RNA | PHARMACOLOGY & PHARMACY | TOXICOLOGY | MICROSOMAL-ENZYME INDUCERS | Transcription, Genetic - drug effects | Up-Regulation | Rats, Wistar | Transcriptional Activation - drug effects | Half-Life | Male | Hepatocytes - metabolism | Promoter Regions, Genetic - drug effects | Dose-Response Relationship, Drug | Glucuronides - metabolism | Transfection | Basic Helix-Loop-Helix Transcription Factors - metabolism | Proteolysis | Phenobarbital - toxicity | Receptors, Aryl Hydrocarbon - metabolism | Hepatocytes - drug effects | Cytochrome P-450 CYP2B1 - biosynthesis | Basic Helix-Loop-Helix Transcription Factors - agonists | Benzo(a)pyrene - toxicity | Basic Helix-Loop-Helix Transcription Factors - genetics | Cells, Cultured | Receptors, Aryl Hydrocarbon - genetics | Enzyme Induction | Rats | Receptors, Cytoplasmic and Nuclear - agonists | Receptors, Cytoplasmic and Nuclear - genetics | Endocrine Disruptors - toxicity | Receptors, Aryl Hydrocarbon - agonists | Drug Synergism | Animals | Thyroid Hormones - metabolism | Glucuronosyltransferase - biosynthesis | Cytochrome P-450 Enzyme Inducers - toxicity | Receptors, Cytoplasmic and Nuclear - metabolism | Enzymes | Phenobarbital | Thyroid hormones | Benzopyrene | Xenobiotics | Food contamination | Cytochrome P-450 | Liquid chromatography | Mass spectrometry | Index Medicus | Receptors | Contaminants | Genes | Breakdown | Ligands | Foods | Hormones | Culture
Journal Article