X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (734) 734
microtubule-binding (546) 546
humans (474) 474
animals (374) 374
biochemistry & molecular biology (327) 327
phosphorylation (306) 306
paired helical filaments (284) 284
tau proteins - metabolism (275) 275
neurosciences (239) 239
alzheimers-disease (232) 232
alzheimer's disease (218) 218
cell biology (206) 206
microtubules - metabolism (172) 172
neurofibrillary tangles (165) 165
proteins (150) 150
tau (144) 144
tau proteins - genetics (134) 134
protein binding (130) 130
protein-tau (129) 129
tau proteins - chemistry (128) 128
alzheimer disease - metabolism (125) 125
microtubule-binding domain (117) 117
mice (115) 115
amino acid sequence (107) 107
molecular sequence data (104) 104
microtubules (102) 102
biophysics (99) 99
tau protein (94) 94
pathology (91) 91
in-vitro (88) 88
article (86) 86
protein (85) 85
brain (84) 84
cytoplasmic dynein (84) 84
dynein (82) 82
research (81) 81
abnormal phosphorylation (80) 80
brain - metabolism (80) 80
male (79) 79
binding sites (77) 77
microtubule-associated proteins - metabolism (75) 75
mutation (75) 75
alzheimer disease - pathology (71) 71
female (71) 71
analysis (68) 68
frontotemporal dementia (67) 67
neurons - metabolism (66) 66
protein structure, tertiary (62) 62
rats (62) 62
transgenic mice (62) 62
clinical neurology (61) 61
multidisciplinary sciences (60) 60
aggregation (59) 59
dyneins - metabolism (59) 59
protein conformation (56) 56
aged (55) 55
macromolecular substances (55) 55
models, molecular (55) 55
cells (54) 54
immunohistochemistry (54) 54
neurodegeneration (54) 54
physiological aspects (54) 54
isoforms (53) 53
mitosis (52) 52
cytoskeleton (50) 50
dyneins - chemistry (50) 50
microtubule-associated proteins - genetics (50) 50
kinesin (49) 49
identification (48) 48
middle aged (48) 48
tau-protein (48) 48
expression (47) 47
localization (47) 47
cells, cultured (46) 46
microscopy, electron (46) 46
tubulin (46) 46
blotting, western (45) 45
disease (44) 44
polymerization (44) 44
tubulin - metabolism (44) 44
microtubule (43) 43
alzheimers disease (42) 42
neurons (42) 42
neurons - pathology (42) 42
progressive supranuclear palsy (41) 41
brain - pathology (40) 40
mental disorders (40) 40
aged, 80 and over (38) 38
cell line (38) 38
glycogen-synthase kinase-3 (38) 38
microtubule binding (38) 38
cell division (37) 37
genetic aspects (37) 37
models, biological (37) 37
neurodegenerative diseases (37) 37
neurofibrillary tangles - metabolism (37) 37
disease models, animal (36) 36
neurology (36) 36
protein structure, secondary (36) 36
mice, transgenic (35) 35
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


NATURE, ISSN 0028-0836, 04/2012, Volume 484, Issue 7394, pp. 345 - U81
Dyneins are microtubule-based AAA(+) motor complexes that power ciliary beating, cell division, cell migration and intracellular transport. Here we report the... 
CYTOPLASMIC DYNEIN | DICTYOSTELIUM | AAA | ATP HYDROLYSIS | TRANSPORT | MECHANISM | MULTIDISCIPLINARY SCIENCES | COILED-COIL | PROTEINS | MICROTUBULE-BINDING DOMAIN | ATPASES
Journal Article
SCIENCE, ISSN 0036-8075, 08/2001, Volume 293, Issue 5534, pp. 1491 - 1495
beta -Amyloid plaques and neurofibrillary tangles (NFTs) are the defining neuropathological hallmarks of Alzheimer's disease, but their pathophysiological... 
PROTEIN | ISOFORMS | MICROTUBULE-BINDING | PHOSPHORYLATION | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | PAIRED HELICAL FILAMENTS | PATHOLOGY | NEUROTOXICITY | AMYOTROPHY | BRAIN
Journal Article
CURRENT ALZHEIMER RESEARCH, ISSN 1567-2050, 12/2010, Volume 7, Issue 8, pp. 656 - 664
Journal Article
European Journal of Cell Biology, ISSN 0171-9335, 06/2019, Volume 98, Issue 2-4, pp. 103 - 115
Spermiogenesis in is a highly conserved process and essential for male fertility. In this haploid phase of spermatogenesis, motile sperm are assembled from... 
THEG | microtubule-binding protein | Proteasome Assembly Chaperone 1 | nuclear shaping | transition-like protein | Y chromosome
Journal Article
by Yang, HD and Zhang, FX and Huang, CJ and Liao, J and Han, Y and Hao, PL and Chu, YJ and Lu, XA and Li, WS and Yu, HT and Kang, JS
MOLECULAR BIOLOGY OF THE CELL, ISSN 1059-1524, 04/2019, Volume 30, Issue 9, pp. 1060 - 1068
Accurate partitioning of chromosomes during mitosis is essential for genetic stability and requires the assembly of the dynamic mitotic spindle and proper... 
MITOSIS | LOCALIZATION | KINETOCHORES | KIF2A | MICROTUBULE-BINDING | CHECKPOINT | BUB1 | MSP58 | 58-KDA MICROSPHERULE PROTEIN | AURORA-B | CELL BIOLOGY | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 02/2012, Volume 482, Issue 7384, pp. 216 - U107
Our understanding of Alzheimer's disease pathogenesis is currently limited by difficulties in obtaining live neurons from patients and the inability to model... 
AMYLOID BETA-PROTEIN | APP | MICROTUBULE-BINDING | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | DOWN-SYNDROME | MOUSE MODEL | TAU | DYSFUNCTION | FIBROBLASTS | SENILE PLAQUES | Neurons - pathology | Coculture Techniques | Humans | Middle Aged | Amyloid beta-Peptides - secretion | tau Proteins - metabolism | Male | Phosphoproteins - metabolism | Endosomes - metabolism | Synapsins - metabolism | Alzheimer Disease - pathology | Cellular Reprogramming | Protease Inhibitors - pharmacology | Amyloid beta-Protein Precursor - secretion | Proteolysis | Amyloid beta-Peptides - metabolism | Amyloid beta-Protein Precursor - metabolism | Aged, 80 and over | Female | Neurons - metabolism | Phosphorylation - drug effects | Neurons - drug effects | Fibroblasts - metabolism | Induced Pluripotent Stem Cells - metabolism | Astrocytes - cytology | Biomarkers - metabolism | Induced Pluripotent Stem Cells - pathology | Peptide Fragments - metabolism | Cells, Cultured | Peptide Fragments - secretion | Glycogen Synthase Kinase 3 - metabolism | Amyloid Precursor Protein Secretases - metabolism | Amyloid beta-Protein Precursor - genetics | Models, Biological | Alzheimer Disease - metabolism | Fibroblasts - cytology | Amyloid Precursor Protein Secretases - antagonists & inhibitors | Enzyme Activation | Messenger RNA | Synthesis | Glycogen | Stem cells | Physiological aspects | Research | Alzheimer's disease | Proteins | Phosphorylation | Neurons | Efficiency | Genomes | Mutation | Alzheimers disease | Index Medicus
Journal Article
Current Biology, ISSN 0960-9822, 09/2018, Volume 28, Issue 17, pp. R943 - R946
A new study finds that a spindle motor makes an unexpected contribution to kinetochore–microtubule attachments and chromosome segregation. A new study finds... 
PP1 | MICROTUBULE-BINDING | KINETOCHORE | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | DYNAMICS | SPINDLE ASSEMBLY CHECKPOINT | CELL BIOLOGY | Chromosomes | Kinesin
Journal Article
Current Biology, ISSN 0960-9822, 02/2017, Volume 27, Issue 4, pp. R150 - R152
Construction of the cell plate during plant cell division requires the precise insertion of materials around the circumferentially growing phragmoplast. New... 
CYTOKINESIS | PROTEIN | MICROTUBULE-BINDING | PRC1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | MIDZONE | CELL BIOLOGY | Cells | Index Medicus
Journal Article
JOURNAL OF CELL BIOLOGY, ISSN 0021-9525, 04/2019, Volume 218, Issue 4, pp. 1298 - 1318
Kinesin-1 is responsible for microtubule-based transport of numerous cellular cargoes. Here, we explored the regulation of kinesin-1 by MAP7 proteins. We found... 
CARGO TRANSPORT | ENSCONSIN | VESICLES | IN-VIVO | TRAFFICKING | MOVEMENT | TAU | MOTORS | SPECIFICATION | MICROTUBULE-BINDING PROTEIN | CELL BIOLOGY | Proteins | Binding | Allosteric properties | Microtubules | Affinity | Kinesin | Recruitment
Journal Article
Nature Genetics, ISSN 1061-4036, 06/2013, Volume 45, Issue 6, pp. 639 - 647
Journal Article
JOURNAL OF CELL SCIENCE, ISSN 0021-9533, 07/2019, Volume 132, Issue 14, p. jcs229054
Microtubule-associated protein tau, an integral component of neurofibrillary tangles, interacts with a variety of signaling molecules. Previously, our... 
MICROTUBULE-BINDING | PHOSPHORYLATION | PROTEIN-KINASE | Tau | NGF | TYROSINE-PHOSPHATASE | CELL BIOLOGY | Tau phosphorylation | SHP2 | GROWTH | PAIRED HELICAL FILAMENTS | CELL-CYCLE | FYN | Alzheimer's disease | CONTRIBUTES | IN-SITU
Journal Article
Journal of cell science, ISSN 0021-9533, 06/2019, Volume 132, Issue 10
Microtubule-associated protein tau, an integral component of neurofibrillary tangles, interacts with a variety of signaling molecules. Previously, our... 
PROTEIN | MICROTUBULE-BINDING | PHOSPHORYLATION | KINASE | tau | NGF | TYROSINE-PHOSPHATASE | CELL BIOLOGY | SHP2 | NEURITE OUTGROWTH | GROWTH | PAIRED HELICAL FILAMENTS | CELL-CYCLE | tau phosphorylation | Alzheimer's disease | IN-SITU
Journal Article
BIOPOLYMERS, ISSN 0006-3525, 08/2016, Volume 105, Issue 8, pp. 557 - 567
Dyneins are multiprotein complexes that move cargo along microtubules in the minus end direction. The largest individual component of the dynein complex is the... 
CYTOPLASMIC DYNEIN | DOMAIN | MICROTUBULE-BINDING | ATPase | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | HYDROLYSIS | NUCLEOTIDE-BINDING | AAA PLUS RING | dynein | microtubule | TRANSPORT | BIOPHYSICS | mechanism | COILED-COIL | POWER STROKE
Journal Article
Nature Cell Biology, ISSN 1465-7392, 03/2012, Volume 14, Issue 3, pp. 224 - 230
In performing its multiple cellular functions, the cytoplasmic dynein motor is subject to complex regulation involving allosteric mechanisms within the dynein... 
NEURONAL MIGRATION | NEURAL STEM-CELLS | DYNACTIN COMPLEX | MOTOR DOMAIN | NUCLEAR-ENVELOPE BREAKDOWN | BETA-III-SPECTRIN | ORGANELLE TRANSPORT | COILED-COIL | MICROTUBULE-BINDING DOMAIN | AAA PLUS RING | CELL BIOLOGY | 1-Alkyl-2-acetylglycerophosphocholine Esterase - metabolism | Animals | Carrier Proteins - metabolism | <