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Toxicology and Applied Pharmacology, ISSN 0041-008X, 2006, Volume 216, Issue 1, pp. 44 - 54
Several pesticides and fungicides commonly used to control agricultural and indoor pests are highly suspected to display endocrine-disrupting effects in... 
Vinclozolin | Mineralocorticoid receptor | Androgen receptor | Glucocorticoid receptor | Estrogen receptors | Progesterone receptor | Fungicide | Reporter cell lines | REPORTER CELL-LINES | glucocorticoid receptor | ANTIANDROGENIC ACTIVITY | MALE-RAT | FUNGICIDE VINCLOZOLIN | PROGESTERONE-RECEPTORS | mineralocorticoid receptor | GENE ASSAYS | vinclozolin | estrogen receptors | progesterone receptor | ENVIRONMENTAL ESTROGENS | IN-VITRO | ENDOCRINE DISRUPTORS | androgen receptor | SEXUAL-DIFFERENTIATION | PHARMACOLOGY & PHARMACY | TOXICOLOGY | reporter cell lines | fungicide | Receptors, Mineralocorticoid - genetics | Androgen Receptor Antagonists | Receptors, Glucocorticoid - antagonists & inhibitors | Luciferases - metabolism | Receptors, Steroid - metabolism | Gene Expression - drug effects | Receptors, Mineralocorticoid - metabolism | Humans | Receptors, Androgen - metabolism | Anilides - chemistry | Tritium | Receptors, Glucocorticoid - metabolism | Receptors, Progesterone - genetics | Receptors, Steroid - antagonists & inhibitors | Receptors, Progesterone - antagonists & inhibitors | Luciferases - genetics | Receptors, Progesterone - metabolism | Dose-Response Relationship, Drug | Dexamethasone - pharmacology | Progesterone Congeners - pharmacology | Metribolone - pharmacology | Mineralocorticoid Receptor Antagonists | Estradiol - pharmacology | Carbamates - pharmacology | Cell Survival - drug effects | Oxazoles - metabolism | Androgen Antagonists - pharmacology | Anilides - metabolism | Aldosterone - pharmacology | Testosterone Congeners - pharmacology | Binding, Competitive - drug effects | Receptors, Androgen - genetics | Receptors, Steroid - genetics | Receptors, Glucocorticoid - genetics | Cell Line, Tumor | Promegestone - pharmacology | Oxazoles - pharmacology | Corticosteroids | Progesterone | Fungicides | Plant metabolites | Estrogen | Index Medicus | ANIMALS | ESTROGENS | METABOLITES | FUNGICIDES | GLUCOCORTICOIDS | PROGESTERONE | ERBIUM SULFIDES | 60 APPLIED LIFE SCIENCES | LUCIFERASE | RISK ASSESSMENT | LIGANDS | ANDROGENS | RECEPTORS
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 7, pp. e11717 - e11717
Background: Tetratricopeptide repeat (TPR) motif containing co-chaperones of the chaperone Hsp90 are considered control modules that govern activity and... 
TRANSCRIPTIONAL ACTIVITY | GLUCOCORTICOID-RECEPTOR | FK506-BINDING IMMUNOPHILIN FKBP51 | MEDIATED TRANSCRIPTION | MOLECULAR CHAPERONES | MULTIDISCIPLINARY SCIENCES | IN-VIVO | X-ASSOCIATED PROTEIN-2 | MAMMALIAN-CELLS | HEAT-SHOCK-PROTEIN | NEGATIVE REGULATOR | Receptors, Mineralocorticoid - genetics | Receptors, Estrogen - metabolism | Immunoprecipitation | Receptors, Steroid - metabolism | Receptors, Mineralocorticoid - metabolism | Humans | Phosphoprotein Phosphatases - metabolism | Receptors, Androgen - metabolism | Immunoblotting | Cyclophilins - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Receptors, Glucocorticoid - metabolism | Receptors, Progesterone - genetics | Tacrolimus Binding Proteins - metabolism | Receptors, Progesterone - metabolism | Nuclear Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Cell Line | HSP40 Heat-Shock Proteins - metabolism | Receptors, Estrogen - genetics | HSP40 Heat-Shock Proteins - genetics | Ubiquitin-Protein Ligases - metabolism | Nuclear Proteins - metabolism | Cyclophilins - genetics | Tacrolimus Binding Proteins - genetics | Animals | Phosphoprotein Phosphatases - genetics | Receptors, Androgen - genetics | Receptors, Steroid - genetics | Receptors, Glucocorticoid - genetics | Cell Line, Tumor | Mice | Ubiquitin-Protein Ligases - genetics | Phosphatases | Corticosteroids | Estrogen | Physiological aspects | Heat shock proteins | Progesterone | Genetic transcription | Comparative analysis | Binding proteins | Cells | Protein binding | Hsp90 protein | Physiological effects | Transcription factors | Transcription | Estrogens | Estrogen receptors | Viruses | Hormones | Chaperones | Phosphatase | Cofactors | Proteins | Hepatitis | Receptors | Reporter gene | Transfection | Physiology | Deoxyribonucleic acid--DNA | Hsp70 protein | C-Terminus | Gene expression | Clients | Progesterone receptors | Tacrolimus | Steroid hormone receptors | Protein phosphatase | Psychiatry | Combinatorial analysis | Binding sites | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 2013, Volume 304, Issue 6, pp. C532 - C540
Gros R, Ding Q, Liu B, Chorazyczewski J, Feldman RD. Aldosterone mediates its rapid effects in vascular endothelial cells through GPER activation. Am J Physiol... 
G protein-coupled estrogen receptor | Proliferation | Aldosterone | Endothelial cells | Vasodilation | Apoptosis | ERK | G protein-coupled receptor 30 | endothelial cells | PHYSIOLOGY | proliferation | STEROIDS | vasodilation | aldosterone | REACTIVITY | apoptosis | RELAXATION | MINERALOCORTICOID RECEPTORS | DILATION | CELL BIOLOGY | COUPLED RECEPTOR 30 | SMOOTH-MUSCLE | REQUIRES | ARTERIOLES | EXPRESSION | Phosphorylation | Receptors, Estrogen - metabolism | Muscle, Smooth, Vascular - metabolism | Receptors, G-Protein-Coupled - metabolism | Apoptosis - drug effects | Receptors, Mineralocorticoid - metabolism | Aorta - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Vasoconstriction - physiology | Aldosterone - metabolism | Phenylephrine - pharmacology | Vasodilation - physiology | Mineralocorticoid Receptor Antagonists | Endothelial Cells - physiology | Muscle, Smooth, Vascular - physiology | Muscle, Smooth, Vascular - drug effects | Vasoconstrictor Agents - pharmacology | Gene Transfer Techniques | Receptors, Estrogen - genetics | Rats | Cardiotonic Agents - pharmacology | Animals | Endothelium-Dependent Relaxing Factors - metabolism | Signal Transduction - drug effects | Cell Proliferation - drug effects | Receptors, G-Protein-Coupled - genetics | Aorta - physiology | Cell proliferation | Receptors | Estrogen | Physiological aspects | G proteins | Research | Health aspects | Endothelium | Cell growth | T cell receptors | Hormones | Index Medicus
Journal Article
Journal of Biomolecular Screening, ISSN 1087-0571, 09/2008, Volume 13, Issue 8, pp. 755 - 765
A major focus in the current discovery of drugs targeting nuclear receptors (NRs) is identifying drugs with reduced side effects by improving selectivity, not... 
Beta-lactamase | High-throughput screening | Cell-based assay | Steroid nuclear hormone receptor | CHEMISTRY, ANALYTICAL | steroid nuclear hormone receptor | high-throughput screening | BIOCHEMICAL RESEARCH METHODS | ALPHA | BETA | REPORTER | POTENT | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | cell-based assay | LINE | beta-lactamase | ANTAGONISTS | MODULATOR | AGONIST | Receptors, Mineralocorticoid - genetics | Receptors, Mineralocorticoid - metabolism | Humans | Receptors, Androgen - metabolism | Estrogen Receptor beta - chemistry | Receptors, Glucocorticoid - metabolism | Receptors, Progesterone - genetics | Recombinant Fusion Proteins - metabolism | Receptors, Progesterone - metabolism | Estrogen Receptor beta - metabolism | Estrogen Receptor beta - genetics | Estrogen Receptor alpha - metabolism | Receptors, Androgen - chemistry | Drug Evaluation, Preclinical | Genes, Reporter | Receptors, Mineralocorticoid - chemistry | Cell Line | Reproducibility of Results | Estrogen Receptor alpha - chemistry | Biological Assay - methods | Receptors, Cytoplasmic and Nuclear - genetics | Estrogen Receptor alpha - genetics | Receptors, Androgen - genetics | Hormones - metabolism | Receptors, Glucocorticoid - genetics | Recombinant Fusion Proteins - genetics | Ligands | Receptors, Glucocorticoid - chemistry | Receptors, Cytoplasmic and Nuclear - metabolism | Receptors, Progesterone - chemistry | Drugs | Usage | Physiological aspects | Product/Service Evaluations | Research | Biological assay | DNA-ligand interactions | Methods | Index Medicus
Journal Article
Circulation, ISSN 0009-7322, 04/2008, Volume 117, Issue 17, pp. 2253 - 2261
Background - In obesity, decreases in adiponectin and increases in proinflammatory adipokines are associated with heart disease. Because adipocytes express... 
Obesity | Adipose tissue | Mineralocorticoid receptor | Diabetes mellitus | Inflammation | Aldosterone | Aldosterone antagonists | MACROPHAGE INFILTRATION | METABOLIC SYNDROME | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | aldosterone | adipose tissue | diabetes mellitus | mineralocorticoid receptor | inflammation | INSULIN-RESISTANCE | CARDIOVASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | aldosterone antagonists | HEMATOLOGY | TYPE-2 DIABETES-MELLITUS | TRANSCRIPTIONAL REGULATION | obesity | ADIPOSE-TISSUE | Diabetes Mellitus, Experimental - drug therapy | Body Weight | Myocardium - immunology | Obesity - drug therapy | Obesity - immunology | Receptors, Mineralocorticoid - metabolism | Male | PPAR gamma - immunology | Adipose Tissue - immunology | RNA, Messenger - metabolism | Inflammation - complications | Inflammation - drug therapy | Mice, Mutant Strains | Adipokines - genetics | Adiponectin - genetics | Diabetes Mellitus, Experimental - complications | Leptin - immunology | Mineralocorticoid Receptor Antagonists | PPAR gamma - genetics | Obesity - complications | Homeostasis - immunology | Aldosterone - pharmacology | Adipokines - immunology | Inflammation - immunology | Leptin - genetics | 3T3-L1 Cells | Diabetes Mellitus, Experimental - immunology | Animals | Triglycerides - blood | Biomarkers | Mice | Adiponectin - immunology | Adipose Tissue - drug effects | Index Medicus | Abridged Index Medicus
Journal Article
Molecular Endocrinology, ISSN 0888-8809, 02/2013, Volume 27, Issue 2, pp. 192 - 202
Journal Article
Kidney International, ISSN 0085-2538, 06/2018, Volume 93, Issue 6, pp. 1344 - 1355
Acute kidney injury induced by ischemia/reperfusion is an independent risk factor for chronic kidney disease. Macrophage recruitment plays an essential role... 
inflammation | macrophage polarization | ischemic injury | ACUTE KIDNEY INJURY | ACTIVATION | CONTRIBUTE | HYPERKALEMIA | REPAIR | SPIRONOLACTONE | DISEASE | UROLOGY & NEPHROLOGY | POLARIZATION | PLASTICITY | AKI | Receptors, Mineralocorticoid - genetics | Kidney - pathology | Receptors, Mineralocorticoid - metabolism | Macrophages, Peritoneal - pathology | Male | Acute Kidney Injury - genetics | Receptors, Mineralocorticoid - drug effects | Kidney - metabolism | Inflammation Mediators - metabolism | Mineralocorticoid Receptor Antagonists - pharmacology | Macrophages, Peritoneal - drug effects | Reperfusion Injury - genetics | Reperfusion Injury - metabolism | Disease Models, Animal | Kidney - drug effects | Reperfusion Injury - pathology | Signal Transduction | Acute Kidney Injury - pathology | Mice, Inbred C57BL | Cells, Cultured | Receptors, Cell Surface - metabolism | Acute Kidney Injury - prevention & control | Mice, Knockout | Phenotype | Animals | Reperfusion Injury - prevention & control | Fibrosis | Acute Kidney Injury - metabolism | Macrophages, Peritoneal - metabolism | Sus scrofa | Naphthyridines - pharmacology | Plasma | Flow cytometry | CD11b antigen | Phenotypes | Kidneys | Dendritic cells | Cytokines | Smooth muscle | Inflammation | Gene expression | Macrophages | Variance analysis | Interleukin 4 | Cell activation | Reperfusion | Ischemia | Granulocytes | Rodents | Kidney diseases | Growth factors | Index Medicus | Life Sciences | Human health and pathology
Journal Article
Journal of Endocrinology, ISSN 0022-0795, 08/2008, Volume 198, Issue 2, pp. 403 - 417
Journal Article
Journal Article