Hematological Oncology, ISSN 0278-0232, 09/2017, Volume 35, Issue 3, pp. 310 - 316
The macrophage inflammatory protein 1α (MIP‐1α) is anticipated to have a role in extranodal natural killer (NK)/T‐cell lymphoma (ENKTL) because the expression...
chemokine | MIP‐1α | extranodal NK/T‐cell lymphoma | extranodal NK/T-cell lymphoma | MIP-1α | extranodal NK | CHEMOKINES | MIP-1 | DIAGNOSED STAGE IV | MIP-1-ALPHA | CANCER | ONCOLOGY | NASAL-TYPE | CCL3 | HEMATOLOGY | EXPRESSION | SMILE | T-cell lymphoma | Cell Proliferation | Prognosis | Humans | Middle Aged | Male | Biomarkers, Tumor | Young Adult | Neoplasm Metastasis | Adolescent | Chemokine CCL3 - blood | Receptors, CCR1 - metabolism | Survival Analysis | Lymphoma, Extranodal NK-T-Cell - mortality | Adult | Chemokine CCL3 - metabolism | Female | Aged | Lymphoma, Extranodal NK-T-Cell - diagnosis | Neoplasm Staging | Lymphoma, Extranodal NK-T-Cell - metabolism | Medical research | Care and treatment | Analysis | Patient outcomes | Medicine, Experimental | Non-Hodgkin's lymphomas | T cells | Macrophages | Cell culture | CC chemokine receptors | Media (culture) | Viruses | Lymphocytes T | Multivariate analysis | CCR1 protein | Bone marrow | Natural killer cells | Deoxyribonucleic acid--DNA | CCR5 protein | Inflammation | Macrophage inflammatory protein 1 | Patients | Survival | Lymphoma | Latency | Serum levels | Medical prognosis | Culture media | Lymphomas | Macrophage inflammatory protein | In vitro methods and tests | Tumors
chemokine | MIP‐1α | extranodal NK/T‐cell lymphoma | extranodal NK/T-cell lymphoma | MIP-1α | extranodal NK | CHEMOKINES | MIP-1 | DIAGNOSED STAGE IV | MIP-1-ALPHA | CANCER | ONCOLOGY | NASAL-TYPE | CCL3 | HEMATOLOGY | EXPRESSION | SMILE | T-cell lymphoma | Cell Proliferation | Prognosis | Humans | Middle Aged | Male | Biomarkers, Tumor | Young Adult | Neoplasm Metastasis | Adolescent | Chemokine CCL3 - blood | Receptors, CCR1 - metabolism | Survival Analysis | Lymphoma, Extranodal NK-T-Cell - mortality | Adult | Chemokine CCL3 - metabolism | Female | Aged | Lymphoma, Extranodal NK-T-Cell - diagnosis | Neoplasm Staging | Lymphoma, Extranodal NK-T-Cell - metabolism | Medical research | Care and treatment | Analysis | Patient outcomes | Medicine, Experimental | Non-Hodgkin's lymphomas | T cells | Macrophages | Cell culture | CC chemokine receptors | Media (culture) | Viruses | Lymphocytes T | Multivariate analysis | CCR1 protein | Bone marrow | Natural killer cells | Deoxyribonucleic acid--DNA | CCR5 protein | Inflammation | Macrophage inflammatory protein 1 | Patients | Survival | Lymphoma | Latency | Serum levels | Medical prognosis | Culture media | Lymphomas | Macrophage inflammatory protein | In vitro methods and tests | Tumors
Journal Article
British Journal of Haematology, ISSN 0007-1048, 10/2003, Volume 123, Issue 1, pp. 106 - 109
The role of serum macrophage inflammatory protein-1 alpha (MIP-1) in bone disease and survival was evaluated in 85 newly diagnosed multiple myeloma (MM)...
receptor activator of nuclear factor | multiple myeloma | macrophage inflammatory protein-1 alpha (MIP-1 | bone disease | macrophage inflammatory protein‐1 alpha (MIP‐1α) | receptor activator of nuclear factor κB | Receptor activator of nuclear factor κB | Bone disease | Macrophage inflammatory protein-1 alpha (MIP-1α) | Multiple myeloma | 1-ALPHA | MM CELLS | RECEPTOR ACTIVATOR | macrophage inflammatory protein-1 alpha (MIP-1 alpha) | HEMATOLOGY | LESIONS | KAPPA-B LIGAND | Carrier Proteins - blood | Bone Resorption | Chemokine CCL4 | Chemokine CCL3 | Receptor Activator of Nuclear Factor-kappa B | Multiple Myeloma - mortality | Humans | Middle Aged | Membrane Glycoproteins - blood | Probability | Male | RANK Ligand | Survival Rate | Biomarkers, Tumor - blood | Stem Cell Transplantation | Multiple Myeloma - pathology | Adult | Female | Macrophage Inflammatory Proteins - blood | Aged | Multiple Myeloma - blood
receptor activator of nuclear factor | multiple myeloma | macrophage inflammatory protein-1 alpha (MIP-1 | bone disease | macrophage inflammatory protein‐1 alpha (MIP‐1α) | receptor activator of nuclear factor κB | Receptor activator of nuclear factor κB | Bone disease | Macrophage inflammatory protein-1 alpha (MIP-1α) | Multiple myeloma | 1-ALPHA | MM CELLS | RECEPTOR ACTIVATOR | macrophage inflammatory protein-1 alpha (MIP-1 alpha) | HEMATOLOGY | LESIONS | KAPPA-B LIGAND | Carrier Proteins - blood | Bone Resorption | Chemokine CCL4 | Chemokine CCL3 | Receptor Activator of Nuclear Factor-kappa B | Multiple Myeloma - mortality | Humans | Middle Aged | Membrane Glycoproteins - blood | Probability | Male | RANK Ligand | Survival Rate | Biomarkers, Tumor - blood | Stem Cell Transplantation | Multiple Myeloma - pathology | Adult | Female | Macrophage Inflammatory Proteins - blood | Aged | Multiple Myeloma - blood
Journal Article
Liver International, ISSN 1478-3223, 02/2011, Volume 31, Issue 2, pp. 245 - 253
Background/aims: To clarify the primary biliary cirrhosis (PBC)‐specific antigen‐presenting mechanism, we examined the distribution and phenotypic...
innate immunity | Langerhans cell | MIP‐3α | biliary epithelial cells | primary biliary cirrhosis | Primary biliary cirrhosis | Innate immunity | MIP-3α | Biliary epithelial cells | DENDRITIC CELLS | INCREASED EXPRESSION | HUMAN LYMPH-NODES | MIP-3 alpha | PROTEIN 3-ALPHA | BILE-DUCTS | INTERFERON | DISEASES | LIVER | ANTIGEN-PRESENTING CELLS | GASTROENTEROLOGY & HEPATOLOGY | IN-SITU | Immunohistochemistry | Mannose-Binding Lectins - metabolism | Chemokine CCL20 - metabolism | Liver Cirrhosis, Biliary - physiopathology | Cytokines - metabolism | Humans | Middle Aged | Cells, Cultured | Male | DNA Primers - genetics | Reverse Transcriptase Polymerase Chain Reaction | Antigens, CD - metabolism | Cell Movement - immunology | Chemokine CCL20 - immunology | Lectins, C-Type - metabolism | Liver Cirrhosis, Biliary - immunology | Langerhans Cells - immunology | Female | Aged | Bile Ducts - immunology
innate immunity | Langerhans cell | MIP‐3α | biliary epithelial cells | primary biliary cirrhosis | Primary biliary cirrhosis | Innate immunity | MIP-3α | Biliary epithelial cells | DENDRITIC CELLS | INCREASED EXPRESSION | HUMAN LYMPH-NODES | MIP-3 alpha | PROTEIN 3-ALPHA | BILE-DUCTS | INTERFERON | DISEASES | LIVER | ANTIGEN-PRESENTING CELLS | GASTROENTEROLOGY & HEPATOLOGY | IN-SITU | Immunohistochemistry | Mannose-Binding Lectins - metabolism | Chemokine CCL20 - metabolism | Liver Cirrhosis, Biliary - physiopathology | Cytokines - metabolism | Humans | Middle Aged | Cells, Cultured | Male | DNA Primers - genetics | Reverse Transcriptase Polymerase Chain Reaction | Antigens, CD - metabolism | Cell Movement - immunology | Chemokine CCL20 - immunology | Lectins, C-Type - metabolism | Liver Cirrhosis, Biliary - immunology | Langerhans Cells - immunology | Female | Aged | Bile Ducts - immunology
Journal Article
Pediatric Blood & Cancer, ISSN 1545-5009, 11/2008, Volume 51, Issue 5, pp. 662 - 668
Background Hemophagocytic lymphohistiocytosis (HLH) is characterized by hypercytokinemia caused by macrophage and T cell activation. We analyzed the serum...
cytokine | interleukin (IL)‐8 | macrophage inflammatory protein‐1β (MIP‐1β) | hemophagocytic lymphohistiocytosis (HLH) | monocyte chemoattractant protein‐1 (MCP‐1) | Hemophagocytic lymphohistiocytosis (HLH) | Interleukin (IL)-8 | Macrophage inflammatory protein-1β (MIP-1β) | Cytokine | Monocyte chemoattractant protein-1 (MCP-1) | interleukin (IL)-8 | CYTOKINES | ACTIVATION | VIRUS | CHEMOKINES | MACROPHAGES | macrophage inflammatory protein-1 beta (MIP-1 beta) | PATHOGENESIS | KAWASAKI-DISEASE | INTERFERON-GAMMA | ONCOLOGY | SEQUENCE | PEDIATRICS | HEMATOLOGY | monocyte chemoattractant protein-1 (MCP-1) | EXPRESSION
cytokine | interleukin (IL)‐8 | macrophage inflammatory protein‐1β (MIP‐1β) | hemophagocytic lymphohistiocytosis (HLH) | monocyte chemoattractant protein‐1 (MCP‐1) | Hemophagocytic lymphohistiocytosis (HLH) | Interleukin (IL)-8 | Macrophage inflammatory protein-1β (MIP-1β) | Cytokine | Monocyte chemoattractant protein-1 (MCP-1) | interleukin (IL)-8 | CYTOKINES | ACTIVATION | VIRUS | CHEMOKINES | MACROPHAGES | macrophage inflammatory protein-1 beta (MIP-1 beta) | PATHOGENESIS | KAWASAKI-DISEASE | INTERFERON-GAMMA | ONCOLOGY | SEQUENCE | PEDIATRICS | HEMATOLOGY | monocyte chemoattractant protein-1 (MCP-1) | EXPRESSION
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 12/2010, Volume 111, Issue 6, pp. 1661 - 1672
Multiple myeloma (MM) is a bone disease that affects many individuals. It was recently reported that macrophage inflammatory protein (MIP)‐1α is constitutively...
ERK1/2 | MIP‐1α | IFN‐β | osteoclast | p38MAPK | IFN-β | MIP-1α | IFN-beta | MULTIPLE-MYELOMA | CELLS | C-FOS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BONE-MARROW | INTERFERON-BETA | INDUCTION | CELL BIOLOGY | OSTEOCLAST | P38MAPK | RECEPTOR ACTIVATOR | ERK 1/2 | TRANSCRIPTION FACTOR | EXPRESSION | MIP-1 alpha | KAPPA-B LIGAND | Cell Line | Butadienes - pharmacology | Nitriles - pharmacology | Enzyme Inhibitors - pharmacology | Proto-Oncogene Proteins c-fos - metabolism | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Chemokine CCL3 - pharmacology | Imidazoles - pharmacology | Signal Transduction - genetics | Extracellular Signal-Regulated MAP Kinases - metabolism | Osteoclasts - cytology | Reverse Transcriptase Polymerase Chain Reaction | Osteoclasts - metabolism | Blotting, Western | Mitogen-Activated Protein Kinase Kinases - metabolism | Animals | Interferon-beta - metabolism | Signal Transduction - drug effects | Interferon Regulatory Factor-3 - metabolism | Mice | Pyridines - pharmacology | p38 Mitogen-Activated Protein Kinases - metabolism | Osteoclasts - drug effects
ERK1/2 | MIP‐1α | IFN‐β | osteoclast | p38MAPK | IFN-β | MIP-1α | IFN-beta | MULTIPLE-MYELOMA | CELLS | C-FOS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BONE-MARROW | INTERFERON-BETA | INDUCTION | CELL BIOLOGY | OSTEOCLAST | P38MAPK | RECEPTOR ACTIVATOR | ERK 1/2 | TRANSCRIPTION FACTOR | EXPRESSION | MIP-1 alpha | KAPPA-B LIGAND | Cell Line | Butadienes - pharmacology | Nitriles - pharmacology | Enzyme Inhibitors - pharmacology | Proto-Oncogene Proteins c-fos - metabolism | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Chemokine CCL3 - pharmacology | Imidazoles - pharmacology | Signal Transduction - genetics | Extracellular Signal-Regulated MAP Kinases - metabolism | Osteoclasts - cytology | Reverse Transcriptase Polymerase Chain Reaction | Osteoclasts - metabolism | Blotting, Western | Mitogen-Activated Protein Kinase Kinases - metabolism | Animals | Interferon-beta - metabolism | Signal Transduction - drug effects | Interferon Regulatory Factor-3 - metabolism | Mice | Pyridines - pharmacology | p38 Mitogen-Activated Protein Kinases - metabolism | Osteoclasts - drug effects
Journal Article
Immunology, ISSN 0019-2805, 06/2006, Volume 118, Issue 2, pp. 153 - 163
Summary CXCL2 (macrophage inflammatory protein‐2 (MIP‐2)), a critical chemokine for neutrophils, has been shown to be produced in the rat intestine in response...
CXCL2 (MIP‐2) | chemokine | intestine | nuclear factor‐κB | TNF | LPS | Chemokine | CXCL2 (MIP-2) | Nuclear factor-κB | Intestine | BOWEL INJURY | RAT INTESTINE | NEUTROPHIL | EOSINOPHILS | MACROPHAGES | KINASE | ENDOTOXIN | nuclear factor-kappa B | IMMUNOLOGY | INTESTINAL EPITHELIAL-CELLS | TUMOR-NECROSIS-FACTOR | MICE | nuclear factor-κB | Original
CXCL2 (MIP‐2) | chemokine | intestine | nuclear factor‐κB | TNF | LPS | Chemokine | CXCL2 (MIP-2) | Nuclear factor-κB | Intestine | BOWEL INJURY | RAT INTESTINE | NEUTROPHIL | EOSINOPHILS | MACROPHAGES | KINASE | ENDOTOXIN | nuclear factor-kappa B | IMMUNOLOGY | INTESTINAL EPITHELIAL-CELLS | TUMOR-NECROSIS-FACTOR | MICE | nuclear factor-κB | Original
Journal Article
British Journal of Haematology, ISSN 0007-1048, 01/2003, Volume 120, Issue 1, pp. 53 - 55
Macrophage inflammatory protein-1 alpha (MIP-1) is a chemokine primarily associated with bone absorption. We examined whether MIP-1 was produced by purified...
chemokine | multiple myeloma | bone lesions | plasma cell purification | MIP-1 | MIP‐1α | Chemokine | Bone lesions | MIP-1α | Multiple myeloma | Plasma cell purification | CHEMOKINES | HEMATOLOGY | MIP-1 alpha | Bone Marrow Cells - chemistry | Cytoplasm - chemistry | Immunohistochemistry | Chemokine CCL4 | Chemokine CCL3 | Humans | Middle Aged | Biomarkers - analysis | RNA, Messenger - analysis | Male | Bone Diseases - metabolism | Chi-Square Distribution | Multiple Myeloma - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Macrophage Inflammatory Proteins - genetics | Female | Aged | Macrophage Inflammatory Proteins - analysis | Tumor Cells, Cultured
chemokine | multiple myeloma | bone lesions | plasma cell purification | MIP-1 | MIP‐1α | Chemokine | Bone lesions | MIP-1α | Multiple myeloma | Plasma cell purification | CHEMOKINES | HEMATOLOGY | MIP-1 alpha | Bone Marrow Cells - chemistry | Cytoplasm - chemistry | Immunohistochemistry | Chemokine CCL4 | Chemokine CCL3 | Humans | Middle Aged | Biomarkers - analysis | RNA, Messenger - analysis | Male | Bone Diseases - metabolism | Chi-Square Distribution | Multiple Myeloma - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Macrophage Inflammatory Proteins - genetics | Female | Aged | Macrophage Inflammatory Proteins - analysis | Tumor Cells, Cultured
Journal Article
Clinical & Experimental Immunology, ISSN 0009-9104, 11/2010, Volume 162, Issue 2, pp. 372 - 378
Summary Infection with Chlamydia pneumoniae (Cp) accounts for around 10% of community acquired bacterial pneumonia and has been associated with other chronic...
lung | CXCL2/MIP‐2 | Chlamydia pneumoniae | epithelium | lymphocytes | CXCL2/MIP-2 | Epithelium | Lymphocytes | Lung | CELLS | SYNDECAN | MIP-2 | ROXITHROMYCIN | IMMUNOLOGY | CHLAMYDOPHILA-PNEUMONIAE | CXCL2 | MULTIPLE-SCLEROSIS | REINFECTION | ASTHMA | PSITTACI | ANTIBIOTIC-TREATMENT | Inflammation - pathology | Lung - microbiology | Epithelial Cells - metabolism | DNA, Bacterial - metabolism | Gene Expression - drug effects | Immunoglobulin G - blood | Gene Expression - genetics | Epithelial Cells - drug effects | Bronchoalveolar Lavage Fluid - immunology | Chlamydophila Infections - pathology | Lipopolysaccharides - immunology | Lymphoid Tissue - immunology | Respiratory Mucosa - pathology | Time Factors | Immunoglobulin G - immunology | Chemokine CXCL2 - genetics | Bronchoalveolar Lavage Fluid - cytology | Lung - metabolism | Chlamydophila Infections - microbiology | Chemokine CXCL2 - metabolism | Chlamydophila pneumoniae | Neutrophils - pathology | Cell Line | Lung - pathology | Immunoglobulin A - metabolism | Mice, Inbred C57BL | Chlamydophila Infections - metabolism | Choristoma - immunology | Lymphoid Tissue - pathology | Lymphocytes - pathology | Animals | Immunoglobulin A - immunology | Lipopolysaccharides - pharmacology | Mice | Bronchoalveolar Lavage Fluid - chemistry | Choristoma - pathology | Respiratory Mucosa - metabolism | Viral antibodies | Pneumonia | Chlamydia | Analysis | Bacterial pneumonia | Antibodies | Macrophages | Mitogens | Lungs | Infections | Animal models | Epithelial cells | Mucosa | Helper cells | Inflammation | Leukocytes (neutrophilic) | Lymphocytes T | Lymphoid tissue | Antibody response | Lipopolysaccharides | DNA | Neutrophilia | Macrophage inflammatory protein | Animal Models
lung | CXCL2/MIP‐2 | Chlamydia pneumoniae | epithelium | lymphocytes | CXCL2/MIP-2 | Epithelium | Lymphocytes | Lung | CELLS | SYNDECAN | MIP-2 | ROXITHROMYCIN | IMMUNOLOGY | CHLAMYDOPHILA-PNEUMONIAE | CXCL2 | MULTIPLE-SCLEROSIS | REINFECTION | ASTHMA | PSITTACI | ANTIBIOTIC-TREATMENT | Inflammation - pathology | Lung - microbiology | Epithelial Cells - metabolism | DNA, Bacterial - metabolism | Gene Expression - drug effects | Immunoglobulin G - blood | Gene Expression - genetics | Epithelial Cells - drug effects | Bronchoalveolar Lavage Fluid - immunology | Chlamydophila Infections - pathology | Lipopolysaccharides - immunology | Lymphoid Tissue - immunology | Respiratory Mucosa - pathology | Time Factors | Immunoglobulin G - immunology | Chemokine CXCL2 - genetics | Bronchoalveolar Lavage Fluid - cytology | Lung - metabolism | Chlamydophila Infections - microbiology | Chemokine CXCL2 - metabolism | Chlamydophila pneumoniae | Neutrophils - pathology | Cell Line | Lung - pathology | Immunoglobulin A - metabolism | Mice, Inbred C57BL | Chlamydophila Infections - metabolism | Choristoma - immunology | Lymphoid Tissue - pathology | Lymphocytes - pathology | Animals | Immunoglobulin A - immunology | Lipopolysaccharides - pharmacology | Mice | Bronchoalveolar Lavage Fluid - chemistry | Choristoma - pathology | Respiratory Mucosa - metabolism | Viral antibodies | Pneumonia | Chlamydia | Analysis | Bacterial pneumonia | Antibodies | Macrophages | Mitogens | Lungs | Infections | Animal models | Epithelial cells | Mucosa | Helper cells | Inflammation | Leukocytes (neutrophilic) | Lymphocytes T | Lymphoid tissue | Antibody response | Lipopolysaccharides | DNA | Neutrophilia | Macrophage inflammatory protein | Animal Models
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 03/2019, Volume 120, Issue 3, pp. 2994 - 3000
Objective We aimed to investigate the association of macrophage inflammatory protein (MIP)‐1α (CCL3) expression with the severity of acute pancreatitis (AP)....
macrophage inflammatory protein‐1α (MIP‐1α) | CCR1/CCR5 | JNK/p38 MAPK signaling pathway | interleukin‐6 (IL‐6) | acute pancreatitis (AP) | interleukin-6 (IL-6) | macrophage inflammatory protein-1α (MIP-1α) | EARLY ENTERAL NUTRITION | FRACTALKINE | CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | INJURY | MAP KINASES | KAPPA-B | MODEL | CELL BIOLOGY | P38 | macrophage inflammatory protein-1 alpha (MIP-1 alpha) | EXPRESSION | CCR5 protein | Interleukin | Pancreatitis | MAP kinase | CCL3 protein | Activation | Inflammation | siRNA | Ribonucleic acid--RNA | Kinases | Patients | Proteins | Time dependence | Signaling | Signal transduction | Protein kinase | Tumor necrosis factor | Biomarkers | Tumor necrosis factor-TNF | Inhibition | Pancreas | Macrophage inflammatory protein | Chemokines | Recombinant
macrophage inflammatory protein‐1α (MIP‐1α) | CCR1/CCR5 | JNK/p38 MAPK signaling pathway | interleukin‐6 (IL‐6) | acute pancreatitis (AP) | interleukin-6 (IL-6) | macrophage inflammatory protein-1α (MIP-1α) | EARLY ENTERAL NUTRITION | FRACTALKINE | CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | INJURY | MAP KINASES | KAPPA-B | MODEL | CELL BIOLOGY | P38 | macrophage inflammatory protein-1 alpha (MIP-1 alpha) | EXPRESSION | CCR5 protein | Interleukin | Pancreatitis | MAP kinase | CCL3 protein | Activation | Inflammation | siRNA | Ribonucleic acid--RNA | Kinases | Patients | Proteins | Time dependence | Signaling | Signal transduction | Protein kinase | Tumor necrosis factor | Biomarkers | Tumor necrosis factor-TNF | Inhibition | Pancreas | Macrophage inflammatory protein | Chemokines | Recombinant
Journal Article
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Full Text
Neutrophil cell surface receptors and their intracellular signal transduction pathways
International Immunopharmacology, ISSN 1567-5769, 11/2013, Volume 17, Issue 3, pp. 638 - 650
Neutrophils play a critical role in the host defense against bacterial and fungal infections, but their inappropriate activation also contributes to tissue...
Signaling | Receptors | Inflammation | Kinases | Neutrophils | ACTIVATED PROTEIN-KINASE | COLONY-STIMULATING FACTOR | LEUKOCYTE ADHESION DEFICIENCY | IMMUNOLOGY | SRC-FAMILY KINASES | HUMAN POLYMORPHONUCLEAR LEUKOCYTES | HIGH-AFFINITY RECEPTOR | TUMOR-NECROSIS-FACTOR | TOLL-LIKE RECEPTORS | PHARMACOLOGY & PHARMACY | BETA-GAMMA-SUBUNITS | NF-KAPPA-B | Signal Transduction - immunology | Animals | Receptors, Cell Surface - immunology | Humans | Neutrophils - immunology | Selectins - immunology | Mycoses | Lectins | Fc receptors | Integrins | FcR, Fc-receptor | GPI, glycosylphosphatidylinositol anchor | CLEC, C-type lectin | OSCAR, osteoclast-associated receptor | PKB, protein kinase B | DAG, diacyl-glycerol | Tyk2, tyrosine protein kinase 2 | VCAM-1, vascular cell adhesion molecule 1 | ICAM-1, intercellular adhesion molecule 1 | FADD, Fas-associated protein with death domain | IκB, inhibitor of NF-κB | GM-CSF, granulocyte | MyD88, myeloid differentiation protein 88 | TNF, tumor necrosis factor | LTβ, lymphotoxin β | TRADD, TNFR1-associated death domain protein | Abl, Abelson leukemia proto-oncogene | SLP-76, SH2 domain-containing leukocyte protein of 76 kDa | CALDAG-GEFI, calcium and DAG-regulated guanine nucleotide exchange factor I | IL, interleukin | Src, Rous sarcoma virus proto-oncogene | IRF, IFN regulatory factor | RIG, retinoic acid-inducible gene | PLC, phospholipase C | TCR, T-cell receptor | IKK, IκB kinase | ITAM, immunoreceptor tyrosine-based activation motif | CARD, caspase activation and recruitment domain | IP3, inositol-tris-phosphate | CHO, Chinese hamster ovary cells | MKK, MAP kinase kinase | fMLP, formly-Met-Leu-Phe | TRAF, TNF receptor-associated factor | MIP, macrophage inflammatory protein | Rac, Ras-related C3 botulinum toxin substrate | monocyte colony-stimulating factor | PIP3, phosphatidylinositol-3-phosphate | VLA-4, very late antigen 4 (α4β1 integrin) | PAF, platelet activating factor | STAT, signal transducer and activator of transcription | TAK, TGFβ-activated kinase 1 | Mac-1, macrophage antigen 1 (αMβ2 integrin) | FcRγ, Fc-receptor γ-chain | Asc, apoptosis-associated speck-like protein containing a CARD | cIAP, cellular inhibitor of apoptosis | BCR, B-cell receptor | Fgr, Gardner–Rasheed feline sarcoma proto-oncogene | VASP, vasodilator-stimulated phosphoprotein | Hck, hematopoietic cell kinase | TGFβ, transforming growth factor β | Rap, Ras-related protein | SHP-1, SH2 domain-containing protein tyrosine phosphatase 1 | Syk, spleen tyrosine kinase | GPCR, G protein-coupled receptor | G-CSF, granulocyte colony-stimulating factor | TREM, triggering receptor expressed on myeloid cells | DISC, death-inducing signaling complex | MDL-1, myeloid DAP12-associating lectin 1 | C3G, Crk SH3 domain-binding guanine nucleotide exchange factor (RapGEF1) | NF-κB, nuclear factor κB | ERM, ezrin-radixin-moesin | Epac1, exchange protein activated by cyclic AMP 1 | LTB4, leukotriene B4 | Mcl, macrophage C-type lectin | SAP130, Sin3A-associated protein of 130 kDa | SH2, Src-homology 2 domain | MAP kinase, mitogen-activated protein kinase | PSGL-1, P-selectin glycoprotein ligand | PI3K, phoshoinositide-3-kinase | ADAP, adhesion and degranulation promoting adapter protein (Fyb, SLAP-130) | NLRP3, NOD-like receptor family, pyrin domain containing 3 | MDA5, melanoma differentiation-associated protein 5 | TLR, Toll-like receptor | GRK, GPCR kinase | LAD, leukocyte adhesion deficiency | MAPKAP-kinase, MAP kinase-associated protein kinase | ZAP-70, ζ-chain-associated protein of 70 kDa | TRAIL, TNF-related apoptosis-inducing ligand | JNK, c-Jun N-terminal kinase | LFA-1, lymphocyte function-associated receptor 1 (αLβ2 integrin) | ROS, reactive oxygen species | RIP3, receptor-interacting serine-threonine protein kinase 3 | DAP12, DNAX activating protein 12 | IFN, interferon | PIR, paired immunoglobulin-like receptor | PKC, protein kinase C | PAK, p21-activated kinase | ESL-1, E-selectin ligand 1 | GAP, GTPase activating protein | ERK, extracellular signal-regulated kinase | SOCS, suppressor of cytokine signaling | JAK, Janus kinase | RANK, receptor activator of NF-κB | IRAK, IL-1 receptor-associated kinase | NOD, nucleotide-binding oligomerization domain containing protein | CEACAM3, carcinoembryonic antigen-related cell adhesion molecule 3 (CD66b)
Signaling | Receptors | Inflammation | Kinases | Neutrophils | ACTIVATED PROTEIN-KINASE | COLONY-STIMULATING FACTOR | LEUKOCYTE ADHESION DEFICIENCY | IMMUNOLOGY | SRC-FAMILY KINASES | HUMAN POLYMORPHONUCLEAR LEUKOCYTES | HIGH-AFFINITY RECEPTOR | TUMOR-NECROSIS-FACTOR | TOLL-LIKE RECEPTORS | PHARMACOLOGY & PHARMACY | BETA-GAMMA-SUBUNITS | NF-KAPPA-B | Signal Transduction - immunology | Animals | Receptors, Cell Surface - immunology | Humans | Neutrophils - immunology | Selectins - immunology | Mycoses | Lectins | Fc receptors | Integrins | FcR, Fc-receptor | GPI, glycosylphosphatidylinositol anchor | CLEC, C-type lectin | OSCAR, osteoclast-associated receptor | PKB, protein kinase B | DAG, diacyl-glycerol | Tyk2, tyrosine protein kinase 2 | VCAM-1, vascular cell adhesion molecule 1 | ICAM-1, intercellular adhesion molecule 1 | FADD, Fas-associated protein with death domain | IκB, inhibitor of NF-κB | GM-CSF, granulocyte | MyD88, myeloid differentiation protein 88 | TNF, tumor necrosis factor | LTβ, lymphotoxin β | TRADD, TNFR1-associated death domain protein | Abl, Abelson leukemia proto-oncogene | SLP-76, SH2 domain-containing leukocyte protein of 76 kDa | CALDAG-GEFI, calcium and DAG-regulated guanine nucleotide exchange factor I | IL, interleukin | Src, Rous sarcoma virus proto-oncogene | IRF, IFN regulatory factor | RIG, retinoic acid-inducible gene | PLC, phospholipase C | TCR, T-cell receptor | IKK, IκB kinase | ITAM, immunoreceptor tyrosine-based activation motif | CARD, caspase activation and recruitment domain | IP3, inositol-tris-phosphate | CHO, Chinese hamster ovary cells | MKK, MAP kinase kinase | fMLP, formly-Met-Leu-Phe | TRAF, TNF receptor-associated factor | MIP, macrophage inflammatory protein | Rac, Ras-related C3 botulinum toxin substrate | monocyte colony-stimulating factor | PIP3, phosphatidylinositol-3-phosphate | VLA-4, very late antigen 4 (α4β1 integrin) | PAF, platelet activating factor | STAT, signal transducer and activator of transcription | TAK, TGFβ-activated kinase 1 | Mac-1, macrophage antigen 1 (αMβ2 integrin) | FcRγ, Fc-receptor γ-chain | Asc, apoptosis-associated speck-like protein containing a CARD | cIAP, cellular inhibitor of apoptosis | BCR, B-cell receptor | Fgr, Gardner–Rasheed feline sarcoma proto-oncogene | VASP, vasodilator-stimulated phosphoprotein | Hck, hematopoietic cell kinase | TGFβ, transforming growth factor β | Rap, Ras-related protein | SHP-1, SH2 domain-containing protein tyrosine phosphatase 1 | Syk, spleen tyrosine kinase | GPCR, G protein-coupled receptor | G-CSF, granulocyte colony-stimulating factor | TREM, triggering receptor expressed on myeloid cells | DISC, death-inducing signaling complex | MDL-1, myeloid DAP12-associating lectin 1 | C3G, Crk SH3 domain-binding guanine nucleotide exchange factor (RapGEF1) | NF-κB, nuclear factor κB | ERM, ezrin-radixin-moesin | Epac1, exchange protein activated by cyclic AMP 1 | LTB4, leukotriene B4 | Mcl, macrophage C-type lectin | SAP130, Sin3A-associated protein of 130 kDa | SH2, Src-homology 2 domain | MAP kinase, mitogen-activated protein kinase | PSGL-1, P-selectin glycoprotein ligand | PI3K, phoshoinositide-3-kinase | ADAP, adhesion and degranulation promoting adapter protein (Fyb, SLAP-130) | NLRP3, NOD-like receptor family, pyrin domain containing 3 | MDA5, melanoma differentiation-associated protein 5 | TLR, Toll-like receptor | GRK, GPCR kinase | LAD, leukocyte adhesion deficiency | MAPKAP-kinase, MAP kinase-associated protein kinase | ZAP-70, ζ-chain-associated protein of 70 kDa | TRAIL, TNF-related apoptosis-inducing ligand | JNK, c-Jun N-terminal kinase | LFA-1, lymphocyte function-associated receptor 1 (αLβ2 integrin) | ROS, reactive oxygen species | RIP3, receptor-interacting serine-threonine protein kinase 3 | DAP12, DNAX activating protein 12 | IFN, interferon | PIR, paired immunoglobulin-like receptor | PKC, protein kinase C | PAK, p21-activated kinase | ESL-1, E-selectin ligand 1 | GAP, GTPase activating protein | ERK, extracellular signal-regulated kinase | SOCS, suppressor of cytokine signaling | JAK, Janus kinase | RANK, receptor activator of NF-κB | IRAK, IL-1 receptor-associated kinase | NOD, nucleotide-binding oligomerization domain containing protein | CEACAM3, carcinoembryonic antigen-related cell adhesion molecule 3 (CD66b)
Journal Article
Contact Dermatitis, ISSN 0105-1873, 04/2008, Volume 58, Issue 4, pp. 193 - 198
Background: Worldwide restrictions in animal use for research have driven efforts to develop alternative methods. Objective: The study aimed to test the...
contact dermatitis | MIP‐1β | THP‐1 cell line | skin‐sensitizing chemicals | Skin-sensitizing chemicals | Contact dermatitis | MIP-1β | THP-1 cell line | ALLERGY | MIP-1 beta | LINE | TEST H-CLAT | LYMPH-NODE ASSAY | skin-sensitizing chemicals | DERMATOLOGY
contact dermatitis | MIP‐1β | THP‐1 cell line | skin‐sensitizing chemicals | Skin-sensitizing chemicals | Contact dermatitis | MIP-1β | THP-1 cell line | ALLERGY | MIP-1 beta | LINE | TEST H-CLAT | LYMPH-NODE ASSAY | skin-sensitizing chemicals | DERMATOLOGY
Journal Article
Virology, ISSN 0042-6822, 2003, Volume 316, Issue 2, pp. 202 - 212
Cytomegaloviruses encode homologs of cellular immune effector proteins, including chemokines (CKs) and CK receptor-like G protein-coupled receptors (GPCRs)....
Viral chemokine | Guinea pig cytomegalovirus | Immune evasion | Amino Acid Sequence | Guinea Pigs | Calcium - metabolism | Viral Proteins - chemistry | Macrophage Inflammatory Proteins - physiology | Molecular Sequence Data | Viral Proteins - genetics | Macrophage Inflammatory Proteins - chemistry | Macrophage Inflammatory Proteins - genetics | Animals | Receptors, Chemokine - physiology | Roseolovirus - genetics | Viral Proteins - physiology | Roseolovirus - immunology | Signal Transduction - physiology | Receptors, CCR1 | Cell Movement | GPCMV-MIP protein
Viral chemokine | Guinea pig cytomegalovirus | Immune evasion | Amino Acid Sequence | Guinea Pigs | Calcium - metabolism | Viral Proteins - chemistry | Macrophage Inflammatory Proteins - physiology | Molecular Sequence Data | Viral Proteins - genetics | Macrophage Inflammatory Proteins - chemistry | Macrophage Inflammatory Proteins - genetics | Animals | Receptors, Chemokine - physiology | Roseolovirus - genetics | Viral Proteins - physiology | Roseolovirus - immunology | Signal Transduction - physiology | Receptors, CCR1 | Cell Movement | GPCMV-MIP protein
Journal Article
Experimental Dermatology, ISSN 0906-6705, 12/2003, Volume 12, Issue 6, pp. 755 - 760
: The inducible epidermal β‐defensins and the chemokine macrophage inflammatory protein‐3α (MIP‐3α/CCL20) are important mediators involved in innate and...
cytokine | calcium | keratinocyte | MIP‐3α/CCL20 | l‐isoleucine | β‐defensin | Keratinocyte | MIP-3α/CCL20 | L-isole ucine | Calcium | β-Defensin | Cytokine | CELLS | IMMUNITY | ANTIBIOTICS | HUMAN SKIN | INNATE | MIP-3 alpha/CCL20 | ANTIMICROBIAL PEPTIDES | PROTEIN 3-ALPHA | DERMATOLOGY | beta-defensin | HUMAN BETA-DEFENSIN-3 | HOST-DEFENSE | DIFFERENTIATION | L-isoleucine | Tumor Necrosis Factor-alpha - metabolism | Up-Regulation | Calcium - metabolism | Skin - metabolism | Humans | Macrophage Inflammatory Proteins - metabolism | Cells, Cultured | Chemokine CCL20 | Interferon-gamma - metabolism | RNA, Messenger - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Dose-Response Relationship, Drug | Isoleucine - pharmacology | Time Factors | Keratinocytes - metabolism | Epidermal Cells | beta-Defensins - metabolism | Cell Culture Techniques | Chemokines, CC - metabolism
cytokine | calcium | keratinocyte | MIP‐3α/CCL20 | l‐isoleucine | β‐defensin | Keratinocyte | MIP-3α/CCL20 | L-isole ucine | Calcium | β-Defensin | Cytokine | CELLS | IMMUNITY | ANTIBIOTICS | HUMAN SKIN | INNATE | MIP-3 alpha/CCL20 | ANTIMICROBIAL PEPTIDES | PROTEIN 3-ALPHA | DERMATOLOGY | beta-defensin | HUMAN BETA-DEFENSIN-3 | HOST-DEFENSE | DIFFERENTIATION | L-isoleucine | Tumor Necrosis Factor-alpha - metabolism | Up-Regulation | Calcium - metabolism | Skin - metabolism | Humans | Macrophage Inflammatory Proteins - metabolism | Cells, Cultured | Chemokine CCL20 | Interferon-gamma - metabolism | RNA, Messenger - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Dose-Response Relationship, Drug | Isoleucine - pharmacology | Time Factors | Keratinocytes - metabolism | Epidermal Cells | beta-Defensins - metabolism | Cell Culture Techniques | Chemokines, CC - metabolism
Journal Article
Clinical & Experimental Immunology, ISSN 0009-9104, 06/2002, Volume 128, Issue 3, pp. 548 - 554
SUMMARY The regulatory role of chemokines and chemokine receptors on specific lymphocyte recruitment into periodontal diseased tissue is poorly characterized....
MIP‐3α | periodontal disease | CCR6 | MIP-3α | Periodontal disease | IMMUNITY | BACTERIA | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | SUBSETS | HEALTHY | IMMUNOLOGY | IMMUNOHISTOLOGICAL ANALYSIS | MIP-3 alpha | LESIONS | INFLAMED HUMAN GINGIVA | SELECTIVE RECRUITMENT | INDUCIBLE EXPRESSION | Original
MIP‐3α | periodontal disease | CCR6 | MIP-3α | Periodontal disease | IMMUNITY | BACTERIA | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | SUBSETS | HEALTHY | IMMUNOLOGY | IMMUNOHISTOLOGICAL ANALYSIS | MIP-3 alpha | LESIONS | INFLAMED HUMAN GINGIVA | SELECTIVE RECRUITMENT | INDUCIBLE EXPRESSION | Original
Journal Article