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Cell, ISSN 0092-8674, 2006, Volume 126, Issue 2, pp. 297 - 308
Half of hereditary nonpolyposis colon cancer kindreds harbor mutations that inactivate MutLα (MLH1•PMS2 heterodimer). MutLα is required for mismatch repair,... 
PCNA | MECHANISM | INITIATION | DNA MISMATCH | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMPLEXES | EXCISION | HETERODIMER | PROTEINS | RECONSTITUTION | RNA-POLYMERASE | CELL BIOLOGY
Journal Article
Genome Medicine, ISSN 1756-994X, 11/2018, Volume 10, Issue 1, pp. 91 - 3
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 03/2018, Volume 24, Issue 6, pp. 1326 - 1336
Purpose: Immune checkpoint inhibition has been shown to generate profound and durable responses in mismatch repair deficient (MMR-D) solid tumors and has... 
COLORECTAL-CANCER PATIENTS | K-RAS | ONCOLOGY | DUCTAL ADENOCARCINOMA | PD-1 BLOCKADE | NORMAL DNA | MUTATIONAL LANDSCAPE | MICROSATELLITE INSTABILITY DETECTION | GENERATION |