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Cancer Cell, ISSN 1535-6108, 07/2015, Volume 28, Issue 1, pp. 11 - 13
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 03/2018, Volume 36, Issue 8, pp. 773 - 779
PurposeNivolumab provides clinical benefit (objective response rate [ORR], 31%; 95% CI, 20.8 to 42.9; disease control rate, 69%; 12-month overall survival... 
CRITERIA | MULTICENTER | MELANOMA | SOLID TUMORS | ONCOLOGY | PD-1 BLOCKADE | OPEN-LABEL | QUALITY-OF-LIFE | DEFICIENCY | GUIDELINE
Journal Article
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 04/2018, Volume 140, Issue 16, pp. 5612 - 5624
Rhodium metalloinsertors are a unique set of metal complexes that bind specifically to DNA base pair mismatches in vitro and kill mismatch repair... 
BASE MISMATCHES | DIIMINE COMPLEXES | RECOGNITION | METALLOINSERTORS | MICROSATELLITE INSTABILITY | DNA | TUMOR-CELLS | BINDING | CHEMISTRY, MULTIDISCIPLINARY | FLUORESCENT-PROBE | CHEMOTHERAPY | Cell proliferation | Rhodium | Analysis | Ligands | Research | Chemical properties | DNA-ligand interactions | Index Medicus
Journal Article
Thyroid, ISSN 1050-7256, 05/2019, Volume 29, Issue 5, pp. 666 - 673
Background: Prior studies have reported mutations in mismatch repair (MMR) genes in a small subset of anaplastic thyroid carcinomas (ATC). The aim of this... 
Thyroid Cancer and Nodules | anaplastic thyroid carcinoma | SURVIVAL | LYNCH-SYNDROME | PROGNOSTIC-FACTORS | MICROSATELLITE INSTABILITY | MUTATION | ENDOCRINOLOGY & METABOLISM | mismatch repair | CANCER | ASSOCIATION | TUMORS
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2017, Volume 12, Issue 8, p. e0182175
Whereas transformation events in hematopoietic malignancies may occur at different developmental stages, the initial mutation originates in hematopoietic stem... 
GENOMIC INSTABILITY | NONPOLYPOSIS COLON-CANCER | MUTATION FREQUENCY | TARGET GENES | HEMATOLOGICAL MALIGNANCY | MICROSATELLITE INSTABILITY | COLORECTAL-CANCER | MULTIDISCIPLINARY SCIENCES | MYELOGENOUS LEUKEMIA | ACUTE MYELOID-LEUKEMIA | MSH2 GENE | Lymphoma - genetics | Thymus Neoplasms - genetics | Tumor Microenvironment | Hematopoietic Stem Cells - metabolism | Thymus Neoplasms - metabolism | Lymphoma - metabolism | Animals | Neoplastic Stem Cells - metabolism | T-Lymphocytes - cytology | Hematopoietic Stem Cells - cytology | MutS Homolog 2 Protein - deficiency | Thymus Neoplasms - pathology | Bone Marrow Transplantation | Neoplastic Stem Cells - pathology | Lymphoma - pathology | Mice | T-Lymphocytes - pathology | Disease Models, Animal | Lymphomas | Genetic aspects | Research | Hematopoietic stem cells | Cell proliferation | Flow cytometry | Transformation | Leukemia | Genes | Irradiated | Stem cell transplantation | Transplantation | Lymphocytes T | DNA repair | Defects | Thymus | Allografts | Developmental stages | Lymphocytes | Hematopoiesis | Mismatch repair | Rodents | Bone marrow | Tumorigenesis | Repair | Deoxyribonucleic acid--DNA | Maturation | MSH2 protein | Lymphoma | Hemopoiesis | Progeny | Thymocytes | Stem cells | Regulatory mechanisms (biology) | Mutation | Tumors | Cancer | Deoxyribonucleic acid | DNA
Journal Article
European Journal of Human Genetics, ISSN 1018-4813, 2015, Volume 23, Issue 8, pp. 1080 - 1084
Journal Article
Biochemistry, ISSN 0006-2960, 12/2011, Volume 50, Issue 50, pp. 10919 - 10928
Journal Article
The American Journal of Surgical Pathology, ISSN 0147-5185, 03/2017, Volume 41, Issue 3, pp. 326 - 333
Mismatch repair (MMR)-deficient endometrial carcinomas (ECs) bearing Lynch syndrome (LS)-associated germline mutations or sporadic MLH1 promoter... 
PD-L1 | mismatch repair | endometrial carcinoma | MLH1 hypermethylation | immunotherapy | Lynch syndrome | SURGERY | MICROSATELLITE INSTABILITY | INFILTRATING LYMPHOCYTES | IMMUNOSCORE | PATHOLOGY | LUNG-CANCER | PROGNOSTIC-FACTOR | IMMUNE-SYSTEM | MICROENVIRONMENT | COLORECTAL-CANCER | BLOCKADE | Immunohistochemistry | Neoplastic Syndromes, Hereditary - pathology | Prognosis | Follow-Up Studies | Endometrial Neoplasms - mortality | Colorectal Neoplasms - genetics | Colorectal Neoplasms, Hereditary Nonpolyposis - pathology | Humans | Middle Aged | Brain Neoplasms - pathology | Endometrial Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Neoplastic Syndromes, Hereditary - metabolism | Brain Neoplasms - metabolism | Neoplastic Syndromes, Hereditary - mortality | Colorectal Neoplasms, Hereditary Nonpolyposis - mortality | DNA Methylation | Endometrial Neoplasms - genetics | DNA Mismatch Repair | Biomarkers, Tumor - metabolism | Female | Neoplastic Syndromes, Hereditary - genetics | Brain Neoplasms - mortality | Colorectal Neoplasms - metabolism | Colorectal Neoplasms - mortality | Promoter Regions, Genetic | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | Brain Neoplasms - genetics | Colorectal Neoplasms, Hereditary Nonpolyposis - metabolism | B7-H1 Antigen - metabolism | MutL Protein Homolog 1 - genetics | Endometrial Neoplasms - pathology | Aged | Biomarkers, Tumor - genetics | Colorectal Neoplasms - pathology
Journal Article
MODERN PATHOLOGY, ISSN 0893-3952, 08/2019, Volume 32, Issue 8, pp. 1168 - 1179
The checkpoint molecule TIM-3 is a target for emerging immunotherapies and has been identified on a variety of malignancies. Mismatch repair-deficient... 
TUMOR-INFILTRATING LYMPHOCYTES | RESPONSES | GERMLINE | INSTABILITY | PD-1 BLOCKADE | DEATH | COLON | LYNCH SYNDROME | PATHOLOGY | UP-REGULATION | NIVOLUMAB PLUS IPILIMUMAB | Immunohistochemistry | MSH6 protein | Yeast | Carcinoma | Immune response | Immune checkpoint | Endometrial cancer | MLH1 protein | Mismatch repair | Immunotherapy | Endometrium | Tumors
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2012, Volume 13, Issue 6, pp. 598 - 606
Journal Article
The American Journal of Surgical Pathology, ISSN 0147-5185, 12/2018, Volume 42, Issue 12, pp. 1686 - 1692
Intestinal-type colorectal adenocarcinomas are graded based on extent of glandular differentiation, although mucinous, signet-ring cell, and solid cancers are,... 
microsatellite instability | mismatch repair deficiency | colorectal carcinoma | COLON-CANCER | SURVIVAL | SURGERY | NUCLEAR MORPHOMETRY | MUCINOUS ADENOCARCINOMA | MICROSATELLITE-INSTABILITY STATUS | PATHOLOGY | Prognosis | Lymphocytes | Analysis | Oncology, Experimental | Colorectal cancer | Outcome and process assessment (Health Care) | Research | Cancer
Journal Article