Molecular Cell, ISSN 1097-2765, 2008, Volume 29, Issue 3, pp. 291 - 301
MutS homologs function in several cellular pathways including mismatch repair (MMR), the process by which mismatches introduced during DNA replication are...
DNA | MICROBIO | SYSTEM | ESCHERICHIA-COLI MUTS | REPLICATION | PROTEIN | PCNA | SLIDING-CLAMP | DNA MISMATCH | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | MUTATOR GENE | IDENTIFICATION | CELL BIOLOGY | MutS DNA Mismatch-Binding Protein - chemistry | Amino Acid Sequence | Green Fluorescent Proteins - metabolism | MutS DNA Mismatch-Binding Protein - metabolism | MutS DNA Mismatch-Binding Protein - analysis | Models, Molecular | Molecular Sequence Data | MutS DNA Mismatch-Binding Protein - isolation & purification | Base Pair Mismatch | Amino Acid Motifs | Bacillus subtilis - genetics | DNA Mismatch Repair | MutS DNA Mismatch-Binding Protein - genetics | Mutation | MutS | MutL | Bacillus subtilis | β-clamp | replication factory | mismatch repair | 2-aminopurine
DNA | MICROBIO | SYSTEM | ESCHERICHIA-COLI MUTS | REPLICATION | PROTEIN | PCNA | SLIDING-CLAMP | DNA MISMATCH | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | MUTATOR GENE | IDENTIFICATION | CELL BIOLOGY | MutS DNA Mismatch-Binding Protein - chemistry | Amino Acid Sequence | Green Fluorescent Proteins - metabolism | MutS DNA Mismatch-Binding Protein - metabolism | MutS DNA Mismatch-Binding Protein - analysis | Models, Molecular | Molecular Sequence Data | MutS DNA Mismatch-Binding Protein - isolation & purification | Base Pair Mismatch | Amino Acid Motifs | Bacillus subtilis - genetics | DNA Mismatch Repair | MutS DNA Mismatch-Binding Protein - genetics | Mutation | MutS | MutL | Bacillus subtilis | β-clamp | replication factory | mismatch repair | 2-aminopurine
Journal Article
IEEE Transactions on Circuits and Systems I: Regular Papers, ISSN 1549-8328, 06/2015, Volume 62, Issue 6, pp. 1508 - 1517
To further enhance the dynamic performance of time-interleaved analog-to-digital converters (TI-ADCs), both linear and nonlinear mismatches should be estimated...
Estimation | analog-to-digital converter | Calibration | Approximation methods | Adaptive calibration | linear mismatches | Convergence | cascaded structure | Nonlinear distortion | mixed mismatches | nonlinear mismatches | time interleaving | Joints | Gain | joint calibration | ERRORS | A/D CONVERTERS | COMPENSATION | RECONSTRUCTION | DIFFERENTIATOR | LEAST-SQUARES | ENGINEERING, ELECTRICAL & ELECTRONIC | TO-DIGITAL CONVERTERS | INTEGRAL NONLINEARITY | SYSTEMS | BAND-LIMITED SIGNALS | Models | Methods | Analog to digital converters | Teknik och teknologier | Engineering and Technology | Elektroteknik och elektronik | Adaptive calibration; analog-to-digital converter; cascaded structure; joint calibration; linear mismatches; mixed mismatches; nonlinear mismatches; time interleaving | Electrical Engineering, Electronic Engineering, Information Engineering
Estimation | analog-to-digital converter | Calibration | Approximation methods | Adaptive calibration | linear mismatches | Convergence | cascaded structure | Nonlinear distortion | mixed mismatches | nonlinear mismatches | time interleaving | Joints | Gain | joint calibration | ERRORS | A/D CONVERTERS | COMPENSATION | RECONSTRUCTION | DIFFERENTIATOR | LEAST-SQUARES | ENGINEERING, ELECTRICAL & ELECTRONIC | TO-DIGITAL CONVERTERS | INTEGRAL NONLINEARITY | SYSTEMS | BAND-LIMITED SIGNALS | Models | Methods | Analog to digital converters | Teknik och teknologier | Engineering and Technology | Elektroteknik och elektronik | Adaptive calibration; analog-to-digital converter; cascaded structure; joint calibration; linear mismatches; mixed mismatches; nonlinear mismatches; time interleaving | Electrical Engineering, Electronic Engineering, Information Engineering
Journal Article
Progress in Biophysics and Molecular Biology, ISSN 0079-6107, 03/2015, Volume 117, Issue 2-3, pp. 149 - 156
DNA mismatch repair (MMR) is a conserved pathway that safeguards genome integrity by correcting replication errors. The coordinated actions of two proteins...
MutL | Processivity sliding clamp and PCNA binding partners | Sequence-unspecific nucleases | Mismatch repair | Lynch syndrome | NUCLEAR IMPORT | SINGLE-MOLECULE | DNA MISMATCH | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | REPAIR PROTEIN MUTS | DISTINCT ROLES | ENDONUCLEASE DOMAIN | BIOPHYSICS | ESCHERICHIA-COLI MUTL | IN-VIVO | C-TERMINAL DOMAIN | Escherichia coli - genetics | MutL Proteins | DNA Damage - genetics | Escherichia coli Proteins - genetics | Adenosine Triphosphatases - chemistry | Adenosine Triphosphatases - genetics | DNA Mismatch Repair - genetics | Escherichia coli Proteins - chemistry | Base Pair Mismatch - genetics | Proteins | Analysis | Discrimination | Atomic force microscopy | Nucleases | DNA binding proteins | Genomics | Life Sciences | Escherichia coli Proteins | Adenosine Triphosphatases | DNA Mismatch Repair | Escherichia coli | Base Pair Mismatch | DNA Damage
MutL | Processivity sliding clamp and PCNA binding partners | Sequence-unspecific nucleases | Mismatch repair | Lynch syndrome | NUCLEAR IMPORT | SINGLE-MOLECULE | DNA MISMATCH | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | REPAIR PROTEIN MUTS | DISTINCT ROLES | ENDONUCLEASE DOMAIN | BIOPHYSICS | ESCHERICHIA-COLI MUTL | IN-VIVO | C-TERMINAL DOMAIN | Escherichia coli - genetics | MutL Proteins | DNA Damage - genetics | Escherichia coli Proteins - genetics | Adenosine Triphosphatases - chemistry | Adenosine Triphosphatases - genetics | DNA Mismatch Repair - genetics | Escherichia coli Proteins - chemistry | Base Pair Mismatch - genetics | Proteins | Analysis | Discrimination | Atomic force microscopy | Nucleases | DNA binding proteins | Genomics | Life Sciences | Escherichia coli Proteins | Adenosine Triphosphatases | DNA Mismatch Repair | Escherichia coli | Base Pair Mismatch | DNA Damage
Journal Article
The EMBO Journal, ISSN 0261-4189, 05/2012, Volume 31, Issue 11, pp. 2528 - 2540
MutS protein recognizes mispaired bases in DNA and targets them for mismatch repair. Little is known about the transient conformations of MutS as it signals...
sliding clamp | MMR | MutS | protein conformational change | DNA mismatch repair | COMPLEX | ATPASE ACTIVITY | MECHANISM | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | HYDROLYSIS | NUCLEOTIDE-BINDING | CELL BIOLOGY | MSH2 | PROTEIN MUTS | MSH2-MSH6 | MODULATION | MutS DNA Mismatch-Binding Protein - chemistry | DNA Mismatch Repair - physiology | MutS DNA Mismatch-Binding Protein - metabolism | Fluorescence Resonance Energy Transfer | MutS DNA Mismatch-Binding Protein - genetics | Protein Conformation | Adenosine Diphosphate - chemistry | Adenosine Triphosphate - chemistry | DNA Mismatch Repair - genetics | Proteins | Signal transduction | Biophysics | Molecular biology | DNA repair | DNA damage
sliding clamp | MMR | MutS | protein conformational change | DNA mismatch repair | COMPLEX | ATPASE ACTIVITY | MECHANISM | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | HYDROLYSIS | NUCLEOTIDE-BINDING | CELL BIOLOGY | MSH2 | PROTEIN MUTS | MSH2-MSH6 | MODULATION | MutS DNA Mismatch-Binding Protein - chemistry | DNA Mismatch Repair - physiology | MutS DNA Mismatch-Binding Protein - metabolism | Fluorescence Resonance Energy Transfer | MutS DNA Mismatch-Binding Protein - genetics | Protein Conformation | Adenosine Diphosphate - chemistry | Adenosine Triphosphate - chemistry | DNA Mismatch Repair - genetics | Proteins | Signal transduction | Biophysics | Molecular biology | DNA repair | DNA damage
Journal Article
Pacific Conservation Biology, ISSN 1038-2097, 2015, Volume 21, Issue 2, pp. 105 - 107
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 07/2012, Volume 40, Issue 12, pp. 5448 - 5464
textabstractMismatch repair (MMR) corrects replication errors such as mismatched bases and loops in DNA. The evolutionarily conserved dimeric MMR protein MutS...
SLIDING CLAMP | RECOGNITION COMPLEX | ATPASE ACTIVITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | HYDROLYSIS | RESONANCE ENERGY-TRANSFER | PROBABILITY-DISTRIBUTION ANALYSIS | TETRAMERIZATION DOMAIN | MSH2-MSH6 | REPAIR PROTEIN MUTS | FRET | MutS DNA Mismatch-Binding Protein - chemistry | MutS DNA Mismatch-Binding Protein - metabolism | Models, Molecular | Spectrometry, Fluorescence | Escherichia coli Proteins - metabolism | Base Pair Mismatch | DNA - metabolism | Nucleotides - chemistry | DNA - chemistry | DNA Mismatch Repair | Fluorescence Resonance Energy Transfer | Protein Binding | Escherichia coli Proteins - chemistry | Fluorescence Polarization | Fluorescent Dyes | Genome Integrity, Repair and | Biological Sciences | Msh2-Msh6 | Repair Protein Muts | Resonance Energy-Transfer | Probability-Distribution Analysis | Hydrolysis | Recognition Complex | Naturvetenskap | Biokemi och molekylärbiologi | Sliding Clamp | Biologiska vetenskaper | Atpase Activity | Biochemistry and Molecular Biology | Tetramerization Domain | Fret | Natural Sciences
SLIDING CLAMP | RECOGNITION COMPLEX | ATPASE ACTIVITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | HYDROLYSIS | RESONANCE ENERGY-TRANSFER | PROBABILITY-DISTRIBUTION ANALYSIS | TETRAMERIZATION DOMAIN | MSH2-MSH6 | REPAIR PROTEIN MUTS | FRET | MutS DNA Mismatch-Binding Protein - chemistry | MutS DNA Mismatch-Binding Protein - metabolism | Models, Molecular | Spectrometry, Fluorescence | Escherichia coli Proteins - metabolism | Base Pair Mismatch | DNA - metabolism | Nucleotides - chemistry | DNA - chemistry | DNA Mismatch Repair | Fluorescence Resonance Energy Transfer | Protein Binding | Escherichia coli Proteins - chemistry | Fluorescence Polarization | Fluorescent Dyes | Genome Integrity, Repair and | Biological Sciences | Msh2-Msh6 | Repair Protein Muts | Resonance Energy-Transfer | Probability-Distribution Analysis | Hydrolysis | Recognition Complex | Naturvetenskap | Biokemi och molekylärbiologi | Sliding Clamp | Biologiska vetenskaper | Atpase Activity | Biochemistry and Molecular Biology | Tetramerization Domain | Fret | Natural Sciences
Journal Article
Hippocampus, ISSN 1050-9631, 03/2012, Volume 22, Issue 3, pp. 389 - 398
The hippocampus is proposed to switch between memory encoding and retrieval by continually computing the overlap between what is expected and what is...
area CA1 | comparator | fMRI | mismatch/mismatch signal | hippocampus | human | Human | Area CA1 | FMRI | Hippocampus | Mismatch/mismatch signal | Comparator | NOVELTY DETECTION | DISTINCT | NEUROSCIENCES | REGION | PATTERN SEPARATION | EPISODIC MEMORY | RESPONSES | mismatch | MEDIAL TEMPORAL-LOBE | DYNAMICS | SYSTEMS | mismatch signal | RECOGNITION MEMORY | Neuropsychological Tests | Magnetic Resonance Imaging | CA1 Region, Hippocampal - physiology | Humans | Brain Mapping | Adult | Female | Male | Memory - physiology | Mismatch signal | Mismatch
area CA1 | comparator | fMRI | mismatch/mismatch signal | hippocampus | human | Human | Area CA1 | FMRI | Hippocampus | Mismatch/mismatch signal | Comparator | NOVELTY DETECTION | DISTINCT | NEUROSCIENCES | REGION | PATTERN SEPARATION | EPISODIC MEMORY | RESPONSES | mismatch | MEDIAL TEMPORAL-LOBE | DYNAMICS | SYSTEMS | mismatch signal | RECOGNITION MEMORY | Neuropsychological Tests | Magnetic Resonance Imaging | CA1 Region, Hippocampal - physiology | Humans | Brain Mapping | Adult | Female | Male | Memory - physiology | Mismatch signal | Mismatch
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2011, Volume 108, Issue 43, pp. 17644 - 17648
Even though high-fidelity polymerases copy DNA with remarkable accuracy, some base-pair mismatches are incorporated at low frequency, leading to spontaneous...
Base pair mismatch | DNA replication | Active sites | Mutagenesis | Hydrogen bonds | DNA | Chemical bases | Crystals | Nucleotides | Tautomers | Polymerase structure | Replication fidelity | Mispair | Crystal structure | TRANSLOCATION | MECHANISM | ACTIVE-SITE | DNA-POLYMERASE-I | NUCLEOTIDE SELECTION | LARGE FRAGMENT | MULTIDISCIPLINARY SCIENCES | CRYSTAL-STRUCTURES | mispair | MISMATCH | REPLICATION | polymerase structure | FIDELITY | replication fidelity | crystal structure | Protons | Hydrogen Bonding | Mass Spectrometry | Mutagenesis - genetics | Models, Molecular | Crystallography, X-Ray | Models, Genetic | Molecular Structure | Mutagenesis - physiology | Base Pair Mismatch - physiology | DNA-Directed DNA Polymerase - metabolism | Base Pair Mismatch - genetics | Research | Chemical properties | Structure | Index Medicus | Biological Sciences
Base pair mismatch | DNA replication | Active sites | Mutagenesis | Hydrogen bonds | DNA | Chemical bases | Crystals | Nucleotides | Tautomers | Polymerase structure | Replication fidelity | Mispair | Crystal structure | TRANSLOCATION | MECHANISM | ACTIVE-SITE | DNA-POLYMERASE-I | NUCLEOTIDE SELECTION | LARGE FRAGMENT | MULTIDISCIPLINARY SCIENCES | CRYSTAL-STRUCTURES | mispair | MISMATCH | REPLICATION | polymerase structure | FIDELITY | replication fidelity | crystal structure | Protons | Hydrogen Bonding | Mass Spectrometry | Mutagenesis - genetics | Models, Molecular | Crystallography, X-Ray | Models, Genetic | Molecular Structure | Mutagenesis - physiology | Base Pair Mismatch - physiology | DNA-Directed DNA Polymerase - metabolism | Base Pair Mismatch - genetics | Research | Chemical properties | Structure | Index Medicus | Biological Sciences
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 05/2012, Volume 40, Issue 9, pp. 3929 - 3938
Mismatch repair (MMR) is an evolutionarily conserved DNA repair system, which corrects mismatched bases arising during DNA replication. MutS recognizes and...
SYSTEM | VISUALIZATION | INACTIVATION | RECOMBINATION | COMPLEX | RECOGNITION | DNA MISMATCH | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI K-12 | PROTEINS | SATURATION | MutL Proteins | MutS DNA Mismatch-Binding Protein - analysis | Recombinant Fusion Proteins - analysis | Base Pair Mismatch | DNA - metabolism | DNA - chemistry | Adenosine Triphosphatases - analysis | Escherichia coli - genetics | DNA Mismatch Repair | Escherichia coli Proteins - genetics | Luminescent Proteins - genetics | MutS DNA Mismatch-Binding Protein - genetics | Adenosine Triphosphatases - genetics | Escherichia coli Proteins - analysis | Fluorescent Dyes | DNA biosynthesis | MMR protein | MutL protein | Base pairs | Fluorescence | Evolution | Replication | mismatch repair | Endonuclease | DNA repair | Communication | Genome Integrity, Repair and
SYSTEM | VISUALIZATION | INACTIVATION | RECOMBINATION | COMPLEX | RECOGNITION | DNA MISMATCH | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI K-12 | PROTEINS | SATURATION | MutL Proteins | MutS DNA Mismatch-Binding Protein - analysis | Recombinant Fusion Proteins - analysis | Base Pair Mismatch | DNA - metabolism | DNA - chemistry | Adenosine Triphosphatases - analysis | Escherichia coli - genetics | DNA Mismatch Repair | Escherichia coli Proteins - genetics | Luminescent Proteins - genetics | MutS DNA Mismatch-Binding Protein - genetics | Adenosine Triphosphatases - genetics | Escherichia coli Proteins - analysis | Fluorescent Dyes | DNA biosynthesis | MMR protein | MutL protein | Base pairs | Fluorescence | Evolution | Replication | mismatch repair | Endonuclease | DNA repair | Communication | Genome Integrity, Repair and
Journal Article
IEEE Transactions on Circuits and Systems II: Express Briefs, ISSN 1549-7747, 01/2016, Volume 63, Issue 1, pp. 29 - 33
The interesting concept of employing in-phase/quadrature (I/Q) downconversion together with time-interleaved analog-to-digital converters allows digitizing...
Radio frequency | Frequency response mismatches | I/Q mismatches | Receivers | wideband analog I/Q downconversion | Distortion | Frequency response | Mirrors | time-interleaved ADCs | digitally assisted analog/RF | Wideband | Digitally assisted analog/radio frequency (RF) | in-phase/quadrature (I/Q) mismatches | 5G radio communication | MISMATCH | time-interleaved analog-to-digital converters (TI-ADCs) | COMPENSATION | frequency response mismatches (FRMs) | wideband (WB) analog I/Q downconversion | ENGINEERING, ELECTRICAL & ELECTRONIC | Frequency response (Electrical engineering) | Research | Digital broadcasting | Radio communications | System dynamics | Architecture | Converters | Devices | Performance degradation | Blinds
Radio frequency | Frequency response mismatches | I/Q mismatches | Receivers | wideband analog I/Q downconversion | Distortion | Frequency response | Mirrors | time-interleaved ADCs | digitally assisted analog/RF | Wideband | Digitally assisted analog/radio frequency (RF) | in-phase/quadrature (I/Q) mismatches | 5G radio communication | MISMATCH | time-interleaved analog-to-digital converters (TI-ADCs) | COMPENSATION | frequency response mismatches (FRMs) | wideband (WB) analog I/Q downconversion | ENGINEERING, ELECTRICAL & ELECTRONIC | Frequency response (Electrical engineering) | Research | Digital broadcasting | Radio communications | System dynamics | Architecture | Converters | Devices | Performance degradation | Blinds
Journal Article
Nature Structural and Molecular Biology, ISSN 1545-9993, 01/2012, Volume 19, Issue 1, pp. 72 - 79
DNA mismatch repair corrects replication errors, thus reducing mutation rates and microsatellite instability. Genetic defects in this pathway cause Lynch...
COMPLEX | ATPASE ACTIVITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | HYDROLYSIS | HMUTS-BETA | REPAIR PROTEIN MUTS | CELL BIOLOGY | MSH6 | BIOPHYSICS | REPEAT INSTABILITY | MSH2-MSH6 | MUTATIONS | BINDING | MutS DNA Mismatch-Binding Protein - chemistry | MutS DNA Mismatch-Binding Protein - metabolism | Humans | Protein Multimerization | Molecular Sequence Data | Substrate Specificity | Crystallography, X-Ray | Adenosine Diphosphate - chemistry | MutS Homolog 2 Protein - metabolism | DNA-Binding Proteins - metabolism | Adenosine Triphosphate - metabolism | DNA Mismatch Repair | MutS DNA Mismatch-Binding Protein - genetics | MutS Homolog 3 Protein | Binding, Competitive | Protein Structure, Tertiary | Amino Acid Sequence | Adenosine Triphosphatases - metabolism | Models, Molecular | MutS Homolog 2 Protein - genetics | DNA - metabolism | DNA-Binding Proteins - genetics | DNA-Binding Proteins - chemistry | MutS Homolog 2 Protein - chemistry | DNA - genetics | Sequence Homology, Amino Acid | DNA - chemistry | Protein Binding | Adenosine Triphosphatases - chemistry | Protein Conformation | Models, Genetic | Adenosine Diphosphate - metabolism | Adenosine Triphosphate - chemistry
COMPLEX | ATPASE ACTIVITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | HYDROLYSIS | HMUTS-BETA | REPAIR PROTEIN MUTS | CELL BIOLOGY | MSH6 | BIOPHYSICS | REPEAT INSTABILITY | MSH2-MSH6 | MUTATIONS | BINDING | MutS DNA Mismatch-Binding Protein - chemistry | MutS DNA Mismatch-Binding Protein - metabolism | Humans | Protein Multimerization | Molecular Sequence Data | Substrate Specificity | Crystallography, X-Ray | Adenosine Diphosphate - chemistry | MutS Homolog 2 Protein - metabolism | DNA-Binding Proteins - metabolism | Adenosine Triphosphate - metabolism | DNA Mismatch Repair | MutS DNA Mismatch-Binding Protein - genetics | MutS Homolog 3 Protein | Binding, Competitive | Protein Structure, Tertiary | Amino Acid Sequence | Adenosine Triphosphatases - metabolism | Models, Molecular | MutS Homolog 2 Protein - genetics | DNA - metabolism | DNA-Binding Proteins - genetics | DNA-Binding Proteins - chemistry | MutS Homolog 2 Protein - chemistry | DNA - genetics | Sequence Homology, Amino Acid | DNA - chemistry | Protein Binding | Adenosine Triphosphatases - chemistry | Protein Conformation | Models, Genetic | Adenosine Diphosphate - metabolism | Adenosine Triphosphate - chemistry
Journal Article
Frontiers in immunology, ISSN 1664-3224, 2019, Volume 10, p. 880
HLA-mismatches in hematopoietic stem-cell transplantation are associated with an impaired overall survival (OS). The aim of this study is to explore whether...
HLA mismatch | PIRCHE | HSCT-hematopoietic stem cell transplant | HLA | Non-permissible mismatch | RECIPIENT | ANTIBODIES | HISTOCHECK | ACUTE GVHD | UNRELATED-DONOR | IMMUNOLOGY | VERSUS-HOST-DISEASE | MOLECULES | DETERMINES NONPERMISSIVE MISMATCHES | CLASS-I MISMATCHES | HLA-DPB1 | HSCT—hematopoietic stem cell transplant
HLA mismatch | PIRCHE | HSCT-hematopoietic stem cell transplant | HLA | Non-permissible mismatch | RECIPIENT | ANTIBODIES | HISTOCHECK | ACUTE GVHD | UNRELATED-DONOR | IMMUNOLOGY | VERSUS-HOST-DISEASE | MOLECULES | DETERMINES NONPERMISSIVE MISMATCHES | CLASS-I MISMATCHES | HLA-DPB1 | HSCT—hematopoietic stem cell transplant
Journal Article
Nature Reviews Cancer, ISSN 1474-175X, 02/2012, Volume 12, Issue 2, pp. 104 - 120
Alkylating agents constitute a major class of frontline chemotherapeutic drugs that inflict cytotoxic DNA damage as their main mode of action, in addition to...
METHYL-N-NITROSOUREA | IN-VIVO SELECTION | PHASE-II TRIAL | O-6-METHYLGUANINE-DNA METHYLTRANSFERASE MGMT | BASE EXCISION-REPAIR | ONCOLOGY | APURINIC/APYRIMIDINIC ENDONUCLEASE APE1 | HAMSTER OVARY CELLS | SMALL-MOLECULE INHIBITORS | MISMATCH REPAIR | RETROVIRUS-MEDIATED EXPRESSION | Base Pair Mismatch | DNA Damage | Alkylating Agents - toxicity | DNA Repair | Humans | Care and treatment | Cell death | Alkylating agents | Patient outcomes | DNA damage | Dosage and administration | Genetic aspects | DNA mismatch repair | Cancer | Toxicity | Cytotoxicity | mismatch repair | Mutation | Base excision repair | Alkylation | epigenetics | Index Medicus
METHYL-N-NITROSOUREA | IN-VIVO SELECTION | PHASE-II TRIAL | O-6-METHYLGUANINE-DNA METHYLTRANSFERASE MGMT | BASE EXCISION-REPAIR | ONCOLOGY | APURINIC/APYRIMIDINIC ENDONUCLEASE APE1 | HAMSTER OVARY CELLS | SMALL-MOLECULE INHIBITORS | MISMATCH REPAIR | RETROVIRUS-MEDIATED EXPRESSION | Base Pair Mismatch | DNA Damage | Alkylating Agents - toxicity | DNA Repair | Humans | Care and treatment | Cell death | Alkylating agents | Patient outcomes | DNA damage | Dosage and administration | Genetic aspects | DNA mismatch repair | Cancer | Toxicity | Cytotoxicity | mismatch repair | Mutation | Base excision repair | Alkylation | epigenetics | Index Medicus
Journal Article