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2011, Methods in molecular biology, ISBN 1617792721, Volume 782., x, 307
Book
Nature Cell Biology, ISSN 1465-7392, 11/2013, Volume 15, Issue 11, pp. 1370 - 1377
The mitotic spindle assembly checkpoint (SAC) delays anaphase onset until all chromosomes have attached to both spindle poles(1,2). Here, we investigated SAC... 
CDC20 | ANEUPLOIDY | ANAPHASE | SATISFY | ROLES | DRIVES | CDK1 | MITOTIC CHECKPOINT | CHROMOSOMAL INSTABILITY | REVEALS | CELL BIOLOGY | M Phase Cell Cycle Checkpoints | Chromosomes, Human | Signal Transduction | Humans | Kinetochores | Spindle Apparatus | Spindle (Cell division) | Cell division | Aneuploidy | Genetic aspects | Cellular signal transduction | Properties | Testing | Index Medicus
Journal Article
Nature Cell Biology, ISSN 1465-7392, 11/2014, Volume 16, Issue 12, pp. 1257 - 1264
Journal Article
BioEssays, ISSN 0265-9247, 03/2015, Volume 37, Issue 3, pp. 257 - 266
Journal Article
Nature Cell Biology, ISSN 1465-7392, 07/2015, Volume 17, Issue 7, pp. 868 - 879
The spindle assembly checkpoint (SAC) is a unique signalling mechanism that responds to the state of attachment of the kinetochore to spindle microtubules. SAC... 
NDC80 COMPLEX | RECRUITMENT | BUDDING YEAST | MPS1 | PHOSPHORYLATION | CHROMOSOME CONGRESSION | KINASE | MICROTUBULE ATTACHMENT | MITOTIC SPINDLE | PROTEIN ARCHITECTURE | CELL BIOLOGY | Phosphorylation | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Saccharomyces cerevisiae - genetics | Tubulin Modulators - pharmacology | Nocodazole - pharmacology | Saccharomyces cerevisiae - drug effects | Saccharomyces cerevisiae - metabolism | Microtubules - metabolism | Spindle Apparatus - metabolism | Cell Cycle Proteins - genetics | Cell Cycle Checkpoints - genetics | Time-Lapse Imaging - methods | Nuclear Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Aurora Kinases - metabolism | Kinetochores - metabolism | Aurora Kinases - genetics | Cell Cycle Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | Cell Cycle Checkpoints - physiology | Nuclear Proteins - metabolism | Signal Transduction - genetics | Saccharomyces cerevisiae Proteins - genetics | Sirolimus - pharmacology | Signal Transduction - drug effects | Cell Cycle Checkpoints - drug effects | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Luminescent Proteins - genetics | Signal Transduction - physiology | Microscopy, Fluorescence | Luminescent Proteins - metabolism | Spindle (Cell division) | Cellular signal transduction | Genetic aspects | Properties | Kinetochores | Index Medicus
Journal Article
Journal Article
Nature Cell Biology, ISSN 1465-7392, 05/2007, Volume 9, Issue 5, pp. 565 - 572
Mad2 has a key role in the spindle-assembly checkpoint (SAC) - the mechanism delaying anaphase onset until all chromosomes correctly attach to the spindle.... 
MITOSIS | CDC20 | ROUGH DEAL | MAD2 | KINETOCHORE | CYCLIN-B | CHROMOSOME MISSEGREGATION | MITOTIC CHECKPOINT | DROSOPHILA | REVEALS | CELL BIOLOGY | Drosophila - drug effects | Anaphase-Promoting Complex-Cyclosome | Colchicine - pharmacology | Microtubule-Associated Proteins - metabolism | Tubulin Modulators - pharmacology | Homeodomain Proteins - metabolism | Drosophila Proteins - metabolism | Drosophila - physiology | Spindle Apparatus - metabolism | Time Factors | Cell Cycle Proteins - genetics | Drosophila - embryology | Mad2 Proteins | Drosophila - genetics | Chromosome Segregation | Kinetochores - metabolism | Cell Cycle Proteins - metabolism | Anaphase - physiology | Phenotype | Animals | Mitosis - drug effects | Ubiquitin-Protein Ligase Complexes - metabolism | Mitosis - physiology | Drosophila Proteins - deficiency | Cyclin B - metabolism | Spindle Apparatus - drug effects | Drosophila Proteins - genetics | Larva - physiology | Mutation | Spindle (Cell division) | Chromosome abnormalities | Mitosis | Drosophila | Lethal mutation | Genetic aspects | Research | Index Medicus | Animal genetics | Tubulin Modulators | Kinetochores | Cellular Biology | Ubiquitin-Protein Ligase Complexes | Life Sciences | Cyclin B | Genetics | Subcellular Processes | Drosophila Proteins | Biochemistry, Molecular Biology | Microtubule-Associated Proteins | Larva | Mitotic Spindle Apparatus | Homeodomain Proteins | Colchicine | Anaphase | Cell Cycle Proteins
Journal Article
Current Biology, ISSN 0960-9822, 02/2019, Volume 29, Issue 3, pp. 449 - 460.e2
During meiosis, diploid progenitor cells undergo one round of DNA replication followed by two rounds of chromosome segregation to form haploid gametes. Once... 
MITOSIS | RECOMBINATION | PROTEIN | BUDDING YEAST | BIOCHEMISTRY & MOLECULAR BIOLOGY | MEIOSIS | MITOTIC EXIT | GAP COMPLEX | DOUBLE-STRAND BREAKS | CELL-CYCLE | SYNAPTONEMAL COMPLEX-FORMATION | CELL BIOLOGY | Genetic research | DNA replication | DNA damage | DNA
Journal Article
New Phytologist, ISSN 0028-646X, 1/2015, Volume 205, Issue 1, pp. 202 - 215
The spindle assembly checkpoint (SAC) is a refined surveillance mechanism which ensures that chromosomes undergoing mitosis do not segregate until they are... 
Proteins | Full papers | Yeasts | Mitosis | Kinetochores | Cell cycle | Giant cells | Plants | Chromosomes | Mitotic spindle apparatus | Plant cells | checkpoint | kinetochore | nematode | giant cell | mitosis | cell cycle | Nematode | Checkpoint | Kinetochore | Giant cell | MAD2 | LOCALIZATION | HISTONE H3 VARIANT | MICROTUBULE-ASSOCIATED PROTEIN | SACCHAROMYCES-CEREVISIAE | PLANT SCIENCES | KINETOCHORES | CHROMOSOME MISSEGREGATION | CELL-CYCLE | MITOTIC CHECKPOINT | LIVING CELLS | M Phase Cell Cycle Checkpoints | Mad2 Proteins - metabolism | Genes, Plant | Microtubule-Associated Proteins - metabolism | Molecular Sequence Data | Protein Subunits - metabolism | Spindle Apparatus | Arabidopsis Proteins - metabolism | Microtubules - metabolism | Metaphase | Gene Expression Regulation, Plant | Cell Cycle Proteins - genetics | Nematoda | Plant Roots - growth & development | Green Fluorescent Proteins - metabolism | Arabidopsis Proteins - genetics | Plant Roots - metabolism | Arabidopsis - cytology | Cell Cycle Proteins - metabolism | Subcellular Fractions - metabolism | Arabidopsis - metabolism | Protein Transport | Arabidopsis - genetics | Two-Hybrid System Techniques | Phenotype | Animals | Mad2 Proteins - genetics | Protein Binding | Arabidopsis - parasitology | Mutation | Anaphase | Arabidopsis thaliana | Analysis | Index Medicus | Life Sciences | Molecular biology | Cellular Biology | Biochemistry, Molecular Biology
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2015, Volume 290, Issue 4, pp. 2431 - 2443
The spindle checkpoint ensures accurate chromosome segregation by monitoring kinetochore-microtubule attachment. Unattached or tensionless ki