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Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2017, Volume 140, Issue 6, pp. 1632 - 1642
Background Eosinophils are a subset of granulocytes that can be involved in the pathogenesis of different diseases, including allergy. Their effector functions... 
Allergy and Immunology | necrosis | eosinophilic disease | reactive oxygen species | non-apoptotic cell death | RIP kinase | Autophagy | mixed lineage kinase-like | eosinophil cytolysis | necroptosis | ACTIVATION | PROGRAMMED NECROSIS | DOMAIN-LIKE | NECROTIC DEATH | EXTRACELLULAR DNA TRAPS | RELEASE | IMMUNOLOGY | CELL-DEATH | ALLERGY | IN-VIVO | PIECEMEAL DEGRANULATION | RIP3 | Protein Kinases - metabolism | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Signal Transduction | Humans | Cells, Cultured | Hypersensitivity - immunology | Molecular Targeted Therapy | Cell Adhesion | Eosinophils - immunology | Immunoglobulins, Intravenous - metabolism | Complement C3b - metabolism | Eosinophilic Esophagitis - immunology | Cytotoxicity, Immunologic | Skin - immunology | Skin diseases | Cell death | Mitogens | Protein kinases | Fluorescence microscopy | TOR protein | Immunohistochemistry | Cytolysis | Cell culture | Reactive oxygen species | Phosphorylation | Intravenous administration | Pathogenesis | Fluorescence | Cytotoxicity | Activation | Kinases | Experiments | Proteins | Signal transduction | Cell activation | Gangrene | Immunoglobulins | Oxygen | Blood & organ donations | Leukocytes (eosinophilic) | Hypersensitivity | Esophagitis | MAP kinase | Rapamycin | Pharmacology | Electron microscopy | Adhesion | Asthma | Signaling | Microscopy | Granular materials | Protein kinase | Morphology | Degranulation | Granules | Skin | Leukocytes (granulocytic) | Phagocytosis | Apoptosis | Eosinophils
Journal Article
Cancer, ISSN 0008-543X, 09/2013, Volume 119, Issue 17, pp. 3148 - 3155
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 2013, Volume 56, Issue 20, pp. 8032 - 8048
Journal Article
International journal of molecular sciences, ISSN 1422-0067, 08/2019, Volume 20, Issue 17, p. 4254
Modern molecular medicine demands techniques to efficiently deliver molecules directly into mammalian cells. As proteins are the final mediators of most... 
necroptotic cell death | mixed-lineage kinase domain-like | apoptotic cell death | protein delivery | caspases | vapor nanobubble photoporation
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 07/2014, Volume 34, Issue 7, pp. 1429 - 1436
OBJECTIVE—Mitogen-activated protein kinase pathways play an important role in neointima formation secondary to vascular injury, in part by promoting... 
neointima | mitogen-activated protein kinase kinase kinase | MLK3 | PROTEIN-KINASE | DOWN-REGULATION | PROLIFERATION | HYPERPLASIA | APOLIPOPROTEIN-E | IN-VIVO | NUCLEOTIDE EXCHANGE FACTOR | PERIPHERAL VASCULAR DISEASE | GENE-TRANSFER | HEMATOLOGY | SIGNAL-REGULATED KINASE | Cell Proliferation | Hyperplasia | Myocytes, Smooth Muscle - pathology | JNK Mitogen-Activated Protein Kinases - metabolism | Neointima | MAP Kinase Kinase Kinases - deficiency | Time Factors | rho-Associated Kinases - metabolism | Carotid Arteries - enzymology | Carotid Artery Injuries - genetics | Rho Guanine Nucleotide Exchange Factors - metabolism | Myocytes, Smooth Muscle - drug effects | Carotid Artery Injuries - pathology | Disease Models, Animal | Muscle, Smooth, Vascular - drug effects | JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors | Signal Transduction | MAP Kinase Kinase Kinases - genetics | Myocytes, Smooth Muscle - enzymology | Mice, Inbred C57BL | Cells, Cultured | Mice, Knockout | Muscle, Smooth, Vascular - pathology | Animals | Carotid Artery Injuries - enzymology | rho GTP-Binding Proteins - metabolism | Carotid Arteries - pathology | Mice | Protein Kinase Inhibitors - pharmacology | Muscle, Smooth, Vascular - enzymology | cJun NH2-terminal kinase | p63RhoGEF | Rho-kinase | vascular smooth muscle cell | mixed-lineage kinase | RhoA
Journal Article
Journal of Neuroimmune Pharmacology, ISSN 1557-1890, 3/2019, Volume 14, Issue 1, pp. 44 - 51
Journal Article
Journal Article
Toxicological Sciences, ISSN 1096-6080, 2012, Volume 126, Issue 1, pp. 162 - 172
The explosive development of nanotechnology has caused an increase in unintended biohazards in humans and in the ecosystem. Similar to particulate matter,... 
Nanoparticles | Zinc oxide | Mixed lineage kinase | Intercellular adhesion molecule | Endothelial cells | endothelial cells | ICAM-1 EXPRESSION | PROTEIN-KINASE | ATHEROSCLEROSIS | KAPPA-B | zinc oxide | MEMBER | nanoparticles | VASCULAR INFLAMMATION | TOXICOLOGY | JNK PATHWAY | STRESS | intercellular adhesion molecule | mixed lineage kinase | EXPOSURE | BRAIN | Gene Expression Regulation, Enzymologic - drug effects | Human Umbilical Vein Endothelial Cells - metabolism | Humans | cdc42 GTP-Binding Protein - metabolism | RNA, Messenger - metabolism | Zinc Oxide - adverse effects | Dose-Response Relationship, Drug | Endothelial Cells - ultrastructure | Endocytosis | Zinc Oxide - chemistry | cdc42 GTP-Binding Protein - antagonists & inhibitors | Aorta, Thoracic - drug effects | Metal Nanoparticles - ultrastructure | Human Umbilical Vein Endothelial Cells - ultrastructure | Cell Survival - drug effects | Human Umbilical Vein Endothelial Cells - drug effects | Endothelial Cells - metabolism | Metal Nanoparticles - chemistry | Cells, Cultured | Enzyme Inhibitors - pharmacology | Metal Nanoparticles - adverse effects | Zinc Oxide - pharmacology | Mice, Transgenic | MAP Kinase Kinase Kinases - metabolism | Particle Size | Aorta, Thoracic - cytology | Intercellular Adhesion Molecule-1 - metabolism | Animals | MAP Kinase Signaling System - drug effects | Intercellular Adhesion Molecule-1 - genetics | rac1 GTP-Binding Protein - antagonists & inhibitors | Mice | rac1 GTP-Binding Protein - metabolism | Endothelial Cells - drug effects | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2011, Volume 286, Issue 43, pp. 37470 - 37482
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 10/2007, Volume 362, Issue 2, pp. 307 - 312
It has been reported that genipin, the aglycone of geniposide, induces apoptotic cell death in human hepatoma cells via a NADPH oxidase-reactive oxygen species... 
Mixed lineage kinase 3 | Reactive oxygen species | terminal kinase | c-Jun NH | Apoptosis | Genipin | NEURONAL APOPTOSIS | c-Jun NH2-terminal kinase | ACTIVATION | HUMAN-DISEASE | MECHANISM | genipin | JNK | BIOCHEMISTRY & MOLECULAR BIOLOGY | apoptosis | HEPATOMA-CELLS | DEATH | FREE-RADICALS | BIOPHYSICS | PATHWAY | reactive oxygen species | mixed lineage kinase 3 | GENIPOSIDE | Prostatic Neoplasms - metabolism | Reactive Oxygen Species - metabolism | Nitriles - pharmacology | Apoptosis - drug effects | Humans | JNK Mitogen-Activated Protein Kinases - metabolism | Male | Green Fluorescent Proteins - genetics | Membrane Potential, Mitochondrial - drug effects | Recombinant Fusion Proteins - metabolism | Dose-Response Relationship, Drug | Flow Cytometry | Transfection | MAP Kinase Kinase Kinases - antagonists & inhibitors | Green Fluorescent Proteins - metabolism | Prostatic Neoplasms - pathology | Butadienes - pharmacology | MAP Kinase Kinase Kinases - genetics | Enzyme Inhibitors - pharmacology | Imidazoles - pharmacology | MAP Kinase Kinase Kinases - metabolism | Mitochondria - metabolism | Mitochondria - drug effects | Enzyme Activation - drug effects | Blotting, Western | Signal Transduction - drug effects | Iridoids - pharmacology | Cell Line, Tumor | Iridoid Glycosides | Recombinant Fusion Proteins - genetics | Mitochondria - physiology
Journal Article
Experimental and Therapeutic Medicine, ISSN 1792-0981, 10/2018, Volume 16, Issue 4, pp. 3317 - 3324
Journal Article
BMC Cancer, ISSN 1471-2407, 07/2018, Volume 18, Issue 1, pp. 736 - 10
Journal Article