X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
mll-rearranged leukemia (59) 59
index medicus (52) 52
humans (44) 44
animals (31) 31
acute myeloid-leukemia (26) 26
leukemia (23) 23
oncology (22) 22
cancer (19) 19
cell biology (18) 18
hemic and lymphatic diseases (18) 18
mice (17) 17
acute lymphoblastic-leukemia (16) 16
mixed-lineage leukemia (16) 16
article (15) 15
cell line, tumor (15) 15
chromatin (15) 15
epigenetics (15) 15
h3k79 methylation (15) 15
leukemia, myeloid, acute - genetics (14) 14
myeloid-lymphoid leukemia protein - genetics (14) 14
dot1l (13) 13
hematology (12) 12
methylation (12) 12
acute myeloid leukemia (11) 11
biochemistry & molecular biology (11) 11
gene expression (11) 11
neoplasms (11) 11
histone-lysine n-methyltransferase - genetics (10) 10
research (10) 10
gene-expression (9) 9
methyltransferases - metabolism (9) 9
proteins (9) 9
transcription factors (9) 9
antineoplastic agents - pharmacology (8) 8
apoptosis (8) 8
dna methylation (8) 8
genetics & heredity (8) 8
histones - metabolism (8) 8
hox gene-expression (8) 8
analysis (7) 7
care and treatment (7) 7
enzymes (7) 7
epigenesis, genetic (7) 7
epigenetic inheritance (7) 7
fusion proteins (7) 7
leukemia, myeloid, acute - drug therapy (7) 7
leukemia, myeloid, acute - pathology (7) 7
methyltransferases - antagonists & inhibitors (7) 7
oncogene proteins, fusion - genetics (7) 7
stem-cells (7) 7
transcription (7) 7
abridged index medicus (6) 6
antineoplastic agents - therapeutic use (6) 6
cells (6) 6
gene expression regulation, leukemic (6) 6
histone-lysine n-methyltransferase - antagonists & inhibitors (6) 6
histone-lysine n-methyltransferase - metabolism (6) 6
histones (6) 6
leukemia, myeloid, acute - metabolism (6) 6
leukemogenesis (6) 6
methyltransferase (6) 6
methyltransferases - genetics (6) 6
mice, inbred c57bl (6) 6
molecular targeted therapy (6) 6
repressive complex 2 (6) 6
research paper (6) 6
review (6) 6
signal transduction (6) 6
transcription factors - metabolism (6) 6
cell proliferation (5) 5
deoxyribonucleic acid--dna (5) 5
development and progression (5) 5
drug discovery (5) 5
enzyme inhibitors - pharmacology (5) 5
female (5) 5
gene rearrangement (5) 5
genetic aspects (5) 5
health aspects (5) 5
hematopoietic stem-cells (5) 5
histone demethylases - antagonists & inhibitors (5) 5
histone demethylases - metabolism (5) 5
infant (5) 5
inhibition (5) 5
lysine (5) 5
mll (5) 5
multidisciplinary sciences (5) 5
mutation (5) 5
myeloid leukemia (5) 5
neoplasms - genetics (5) 5
prognosis (5) 5
proto-oncogene proteins - metabolism (5) 5
rna-polymerase-ii (5) 5
transformation (5) 5
acute myelogenous leukemia (4) 4
aml (4) 4
binding sites (4) 4
blotting, western (4) 4
cell cycle (4) 4
cell proliferation - drug effects (4) 4
cell transformation, neoplastic - genetics (4) 4
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Cold Spring Harbor Perspectives in Medicine, ISSN 2157-1422, 11/2017, Volume 7, Issue 11, p. a026658
Journal Article
Blood, ISSN 0006-4971, 03/2014, Volume 123, Issue 12, pp. 1870 - 1882
Journal Article
Cancer Letters, ISSN 0304-3835, 2015, Volume 372, Issue 2, pp. 157 - 165
Highlights • miR-26a is significantly down-regulated in MLL -rearranged AML. • miR-26a plays a critical anti-leukemic function both in vitro and in vivo. •... 
Hematology, Oncology and Palliative Medicine | Post-transcription regulation | TET1 | MLL-rearranged leukemia | miR-26a | MYC | MiR-26a | TRANSFORMATION | STEM-CELLS | MAMMALIAN DNA | ACUTE MYELOID-LEUKEMIA | MICRORNA EXPRESSION PROFILES | ONCOLOGY | CELL SELF-RENEWAL | MIXED-LINEAGE-LEUKEMIA | IN-VIVO | TARGETS | HUMAN CANCERS | Myeloid-Lymphoid Leukemia Protein - metabolism | Cell Proliferation | Humans | MicroRNAs - metabolism | DNA-Binding Proteins - metabolism | Mixed Function Oxygenases | Leukemia, Myeloid, Acute - enzymology | Transfection | Time Factors | Cell Transformation, Neoplastic - genetics | Bone Marrow Transplantation | Transcription, Genetic | 3' Untranslated Regions | Binding Sites | Proto-Oncogene Proteins - metabolism | Histone-Lysine N-Methyltransferase - genetics | Signal Transduction | Cell Survival | Leukemia, Myeloid, Acute - pathology | Mice, Inbred C57BL | Gene Fusion | Proto-Oncogene Proteins - genetics | Gene Expression Regulation, Leukemic | DNA-Binding Proteins - genetics | Cell Transformation, Neoplastic - metabolism | Proto-Oncogene Proteins c-myc - metabolism | Gene Expression Regulation, Enzymologic | Animals | Histone-Lysine N-Methyltransferase - metabolism | Myeloid-Lymphoid Leukemia Protein - genetics | Gene Rearrangement | Cell Line, Tumor | MicroRNAs - genetics | Proto-Oncogene Proteins c-myc - genetics | Cell Transformation, Neoplastic - pathology | Leukemia, Myeloid, Acute - genetics | Proteins | Nanoparticles | Medical research | Pathogenesis | Genes | Leukemia | Cancer | post-transcription regulation
Journal Article
Genes & Development, ISSN 0890-9369, 06/2016, Volume 30, Issue 11, pp. 1278 - 1288
Acute myeloid leukemias (AMLs) with a rearrangement of the mixed-linage leukemia (MLL) gene are aggressive hematopoietic malignancies. Here, we explored the... 
Epigenetics | Histone demethylase | JMJD2 | Interleukin 3 | Acute myeloid leukemia | H3K9 methylation | STEM-CELLS | ACUTE MYELOGENOUS LEUKEMIA | RECEPTOR-ALPHA CHAIN | DOT1L | HISTONE DEMETHYLASES | DEVELOPMENTAL BIOLOGY | IDENTIFICATION | histone demethylase | CANCER | epigenetics | MLL-REARRANGED LEUKEMIA | FAMILY | CELL BIOLOGY | TRIMETHYLATION | acute myeloid leukemia | interleukin 3 | GENETICS & HEREDITY | Cell Survival - drug effects | Cell Survival - genetics | Jumonji Domain-Containing Histone Demethylases - genetics | Mice, Knockout | Leukemia, Myeloid, Acute - enzymology | Animals | Cell Differentiation - drug effects | Interleukin-3 Receptor alpha Subunit - genetics | Jumonji Domain-Containing Histone Demethylases - antagonists & inhibitors | Tamoxifen - therapeutic use | Tamoxifen - pharmacology | Cell Line, Tumor | Leukemia, Myeloid, Acute - drug therapy | Protein Binding | Tamoxifen - analogs & derivatives | Cell Proliferation - drug effects | Mice | Gene Expression Regulation, Neoplastic - drug effects | Interleukin-3 Receptor alpha Subunit - metabolism | Methylation | Jumonji Domain-Containing Histone Demethylases - metabolism | Leukemia, Myeloid, Acute - physiopathology | Disease Models, Animal | Leukemia, Myeloid, Acute - genetics | Genetic aspects | Nonlymphoid leukemia | Research | Myelocytic leukemia | Methyltransferases | Gene expression | Research Paper
Journal Article
Journal Article
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 2099 - 13
Effective therapy of acute myeloid leukemia (AML) remains an unmet need. DNA methyl-cytosine dioxygenase Ten-eleven translocation 1 (TET1) is a critical... 
STEM-CELLS | ACTIVATION | B-CELL | SIGNALING PATHWAY | MULTIDISCIPLINARY SCIENCES | STAT3 | RESISTANCE | ADULTS | TET1 | CANCER | MLL-REARRANGED LEUKEMIA | Humans | Leukemia, Myeloid, Acute - metabolism | Mixed Function Oxygenases - metabolism | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Enzyme Inhibitors - administration & dosage | STAT5 Transcription Factor - genetics | STAT5 Transcription Factor - metabolism | RNA Interference | STAT5 Transcription Factor - antagonists & inhibitors | Leukemia, Myeloid, Acute - drug therapy | Daunorubicin - administration & dosage | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Leukemia, Experimental - genetics | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Leukemia, Experimental - drug therapy | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Kaplan-Meier Estimate | THP-1 Cells | Gene Expression Regulation, Leukemic - drug effects | Proto-Oncogene Proteins - genetics | Mixed Function Oxygenases - antagonists & inhibitors | Animals | Cell Line, Tumor | Mixed Function Oxygenases - genetics | STAT3 Transcription Factor - antagonists & inhibitors | Leukemia, Experimental - metabolism | Leukemia, Myeloid, Acute - genetics | Translocation | Dioxygenase | Data analysis | Transcription factors | Transcription | Myeloid leukemia | Leukemia | Stat3 protein | Data processing | Drug screening | Synergistic effects | Chemotherapy | Acute myeloid leukemia | Viability | Deoxyribonucleic acid--DNA
Journal Article