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Matrix metalloproteinases: the most important pathway involved with periodontal destruction, 12/2005
Periodontitis is an infectious disease estimated to occur in approximately a third of adults over the age of 35, being the major cause of adult tooth loss. The... 
MMP, cytokine, periodontitis, genes polymorphisms
Journal
Genes & Diseases, ISSN 2352-3042, 03/2015, Volume 2, Issue 1, pp. 26 - 34
Since the identification of matrix metalloproteinases (MMPs), a family of zinc-dependent endopeptidases, as being a driving factor for cancer progression and... 
Inhibitors | Matrix metalloproteinases | Metastasis | MMPs | Cancer
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2018, Volume 13, Issue 11, pp. e0207240 - e0207240
Irreversible cartilage collagen breakdown by the collagenolytic matrix metalloproteinases (MMPs)-1 and MMP-13 represents a key event in pathologies associated... 
TRANSCRIPTION FACTORS | INTERLEUKIN-1 | DE-NOVO SYNTHESIS | ONCOSTATIN-M | C-FOS | CARTILAGE COLLAGEN BREAKDOWN | MATRIX-METALLOPROTEINASE | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | PROINFLAMMATORY CYTOKINES | AP-1 | Interleukin-1 - metabolism | Promoter Regions, Genetic | Humans | Cells, Cultured | Proto-Oncogene Proteins c-fos - metabolism | Activating Transcription Factor 3 - metabolism | Apoptosis Regulatory Proteins - metabolism | Matrix Metalloproteinase 13 - metabolism | Gene Expression Regulation, Enzymologic | Cell Nucleus - metabolism | Time Factors | Computer Simulation | Transcription, Genetic | Interleukin-1 - administration & dosage | Matrix Metalloproteinase 1 - metabolism | Chondrocytes - metabolism | Matrix Metalloproteinase 1 - genetics | Cysteine | Cellular signal transduction | Research | Cytokines | Cartilage cells | Gene expression | Regulators | Chromatin | Transcription factors | Matrix metalloproteinases | Immunoprecipitation | Wnt protein | Genes | Gene regulation | Serine | Arthritis | Kinases | Proteins | Cartilage | Signal transduction | Biomedical materials | Tumor necrosis factor-TNF | Biocompatibility | Deoxyribonucleic acid--DNA | Binding | RNA-mediated interference | Activating transcription factor 3 | Activator protein 1 | Inflammation | siRNA | Collagenase 3 | Medicine | Ribonucleic acids | Rheumatoid arthritis | Collagen | Chondrocytes | Regulation | Osteoarthritis | Cartilage diseases | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 09/2012, Volume 109, Issue 38, pp. 15431 - 15436
Journal Article
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 6/2014, Volume 34, Issue 6, pp. 1179 - 1186
Journal Article
Biochemical Journal, ISSN 0264-6021, 05/2007, Volume 403, Issue 3, pp. 553 - 563
We previously reported that CS (chondroitin sulfate) GAG (glycosaminoglycan), expressed on MCSP (melanoma-specific CS proteoglycan), is important for... 
Proteoglycan | Matrix metalloproteinase (MMP) | Chondroitin sulfate | Membrane-type 3 MMP (MT3-MMP) | Tissue inhibitor of metalloproteinases-2 (TIMP-2) | Sulfation | membrane-type 3 MMP (MT3-MMP) | TUMOR PROGRESSION | chondroitin sulfate | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEMOPEXIN-LIKE DOMAIN | MEMBRANE-TYPE-1 MATRIX-METALLOPROTEINASE | NG2 PROTEOGLYCAN | proteoglycan | PROGELATINASE-A | tissue inhibitor of metalloproteinases-2 (TIMP-2) | matrix metalloproteinase (MMP) | CDNA LIBRARY | sulfation | EXTRACELLULAR-MATRIX | MT-MMPS | EXPRESSION | AUTOPROTEOLYTIC ACTIVATION | Melanoma - metabolism | Protein Structure, Tertiary | Humans | Chondroitin Sulfate Proteoglycans - metabolism | Metalloendopeptidases - metabolism | Chondroitin Sulfates - physiology | Enzyme Precursors - metabolism | Matrix Metalloproteinase 16 - physiology | Gelatinases - metabolism | Tissue Inhibitor of Metalloproteinase-2 - pharmacology | Matrix Metalloproteinase Inhibitors | Membrane Proteins - metabolism | Tumor Cells, Cultured | Index Medicus | βDX, p-nitro-β-D-xylopyranoside | MCSP, melanoma-specific CS proteoglycan | ECM, extracellular matrix | GAG, glycosaminoglycan | APMA, 4-aminophenylmercuric acetate | MT-MMP, membrane-type MMP | TIMP-2, tissue inhibitor of metalloproteinases-2 | CDMMP-2, C-terminal domain of MMP-2 | BAP, Escherichia coli bacterial alkaline phosphatase | HRP, horseradish peroxidase | ECL, enhanced chemiluminescence | HA, hyaluronan | IDV, individual values | IPTG, isopropyl β-D-thiogalactoside | C4S, chondroitin 4-sulfate | ConA, concanavalin A | MMP, matrix metalloproteinase | CS, chondroitin sulfate
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2016, Volume 11, Issue 3, pp. e0152474 - e0152474
Aims Mice deficient in IL-1 receptor 1 (hence unresponsive to both IL-1 isoforms a and beta) have impaired expansive arterial remodeling due to diminished... 
COLLAGEN ACCUMULATION | RHEUMATOID-ARTHRITIS | MATRIX METALLOPROTEINASES | ATHEROSCLEROTIC PLAQUES | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | HEART-FAILURE | INTERLEUKIN-1-BETA INHIBITION | GENE-EXPRESSION | SMOOTH-MUSCLE-CELLS | ANAKINRA | Immunohistochemistry | Muscle, Smooth, Vascular - metabolism | Humans | Immunoblotting | RNA, Messenger - metabolism | Arteries - metabolism | Matrix Metalloproteinase 9 - metabolism | Matrix Metalloproteinase 9 - genetics | Matrix Metalloproteinase 1 - genetics | Enzyme-Linked Immunosorbent Assay | Interleukin-1 - analysis | Cells, Cultured | Matrix Metalloproteinase 3 - metabolism | Protein Isoforms - analysis | Matrix Metalloproteinase 3 - analysis | Muscle, Smooth, Vascular - cytology | Interleukin-1 - pharmacology | Protein Isoforms - pharmacology | Cell Movement - drug effects | Animals | Cathepsins - genetics | Signal Transduction - drug effects | Cathepsins - metabolism | Mice | Matrix Metalloproteinase 1 - metabolism | Matrix Metalloproteinase 3 - genetics | Interleukin-1 | Analysis | Influence | Cellular signal transduction | Inflammation | Research | Risk factors | Matrix metalloproteinases | Smooth muscle | Cardiovascular disease | Interleukin 1 receptors | Matrix metalloproteinase | Remodeling | Medical schools | Proteins | Actin | Rodents | Atherosclerosis | Interleukin 1 | Extracellular matrix | Expansion | Plaques | Enzyme-linked immunosorbent assay | Interstitial collagenase | Enzymes | Medical research | Cytokines | Redundancy | Muscles | Principal components analysis | Cathepsin S | Regression analysis | Gelatinase B | Medicine | Studies | Signaling | Hospitals | Womens health | Rheumatoid arthritis | Arteriosclerosis | Coronary vessels | Isoforms | Cardiovascular diseases | Index Medicus
Journal Article
Biomolecules & Therapeutics(구 응용약물학회지), ISSN 1976-9148, 2018, Volume 26, Issue 6, p. 560
In the present study, we tried to examine whether resveratrol regulates the expression of matrix metalloproteinases (MMPs) through affecting nuclear... 
Resveratrol | Chondrocytes | MMPs | Osteoarthritis
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2018, Volume 13, Issue 12, pp. e0208800 - e0208800
Journal Article
Frontiers in Bioscience - Scholar, ISSN 1945-0516, 06/2015, Volume 7S, Issue 1, pp. 125 - 149
Journal Article
Biomolecules and Therapeutics, ISSN 1976-9148, 11/2018, Volume 26, Issue 6, pp. 560 - 567
Journal Article
Life Sciences, ISSN 0024-3205, 09/2019, Volume 232, pp. 116614 - 116614
SRY-box 18 (SOX18) is a transcription factor known for its role in regulating cell differentiation and lymphatic and blood vessel development. It has been... 
Cell invasion | SOX18 | Bladder cancer | Cell cycle | MMPs
Journal Article
Japanese Journal of Infectious Diseases, ISSN 1344-6304, 2015
Disease severities following Dengue virus (DV) infection are caused by increased vascular permeability leading to hypovolemic shock. Matrix metalloproteinases... 
Dengue | MMPs | TIMPs
Journal Article
Anatomical Record, ISSN 1932-8486, 2019
It is now widely appreciated that members of the matrix metalloproteinase (MMP) family of enzymes play a key role in cancer development and progression along... 
biofluids | cancer | urine | biomarkers | extracellular matrix | MMPs
Journal Article
Journal of Basic and Clinical Physiology and Pharmacology, ISSN 0792-6855, 05/2019, Volume 30, Issue 3
The etiology of gingival overgrowth due to cyclosporine A (CsA) is still unknown. The aim of this study was to determine the possible role of matrix... 
Fibroblasts
Journal Article
Turkish Nephrology, Dialysis and Transplantation Journal, ISSN 1300-7718, 2018, Volume 27, Issue 1, pp. 49 - 56
Journal Article
Nutrition, ISSN 0899-9007, 01/2017, Volume 33, pp. 1 - 13
Osteoarthritis (OA) is characterized by cartilage degradation in the affected joints. Pomegranate fruit extract (PFE) inhibits cartilage degradation in vitro.... 
Rabbit | PGE2 | ACLT | Osteoarthritis | Pomegranate | MMPs | PGE | Index Medicus
Journal Article
Turkish Journal of Gastroenterology, ISSN 1300-4948, 01/2018, Volume 29, Issue 1, pp. 13 - 20
Journal Article
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