Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (72956) 72956
Newsletter (7780) 7780
Publication (7741) 7741
Newspaper Article (1989) 1989
Book Chapter (666) 666
Book Review (593) 593
Magazine Article (426) 426
Conference Proceeding (209) 209
Reference (119) 119
Book / eBook (94) 94
Trade Publication Article (54) 54
Transcript (29) 29
Dissertation (13) 13
Data Set (6) 6
Paper (6) 6
Report (1) 1
Technical Report (1) 1
Web Resource (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (35174) 35174
animals (22443) 22443
genetically modified organisms (20397) 20397
genetic engineering (18121) 18121
analysis (14652) 14652
plant sciences (14286) 14286
humans (13306) 13306
research (12497) 12497
biochemistry & molecular biology (11115) 11115
plants, genetically modified (11008) 11008
proteins (10595) 10595
animals, genetically modified (10003) 10003
gene expression (9909) 9909
plants (9601) 9601
genes (9446) 9446
expression (8785) 8785
cell biology (7950) 7950
biotechnology & applied microbiology (7569) 7569
biotechnology (7554) 7554
life sciences (7422) 7422
physiological aspects (7406) 7406
mice (7267) 7267
genetic aspects (7051) 7051
genetic research (7026) 7026
gene expression regulation, plant (6805) 6805
arabidopsis - genetics (6443) 6443
female (6108) 6108
molecular sequence data (6090) 6090
transgenic plants (5791) 5791
plants, genetically modified - genetics (5786) 5786
male (5636) 5636
mutation (5479) 5479
plant proteins - genetics (5344) 5344
enzymes (4894) 4894
research article (4877) 4877
multidisciplinary sciences (4725) 4725
gene (4701) 4701
arabidopsis thaliana (4664) 4664
arabidopsis (4574) 4574
plant proteins - metabolism (4568) 4568
amino acid sequence (4377) 4377
electrochemistry (4252) 4252
article (4187) 4187
plants, genetically modified - metabolism (4129) 4129
chemistry, analytical (4096) 4096
cancer (4060) 4060
gene-expression (4040) 4040
protein (3952) 3952
arabidopsis proteins - genetics (3945) 3945
arabidopsis-thaliana (3844) 3844
base sequence (3781) 3781
fungi (3761) 3761
dna (3726) 3726
phenotype (3692) 3692
health aspects (3683) 3683
arabidopsis proteins - metabolism (3656) 3656
food and beverages (3583) 3583
genomics (3535) 3535
biology (3528) 3528
developmental biology (3491) 3491
arabidopsis - metabolism (3419) 3419
cells (3304) 3304
tobacco - genetics (3288) 3288
medicine (3278) 3278
chemistry (3264) 3264
rna (3207) 3207
growth (3167) 3167
genetics (3134) 3134
signal transduction (3119) 3119
microbiology (3084) 3084
science (3055) 3055
neurosciences (3036) 3036
biosynthesis (3033) 3033
biochemistry, general (2976) 2976
genetics & heredity (2927) 2927
rice (2796) 2796
genetically modified plants (2714) 2714
reports (2685) 2685
food (2665) 2665
genomes (2657) 2657
rats (2648) 2648
molecular biology (2620) 2620
drosophila (2601) 2601
transcription factors - genetics (2580) 2580
biochemical research methods (2575) 2575
nanoparticles (2566) 2566
food science & technology (2531) 2531
identification (2474) 2474
universities and colleges (2457) 2457
agriculture (2426) 2426
genes, plant (2414) 2414
biophysics (2395) 2395
phylogeny (2348) 2348
fluorescence (2345) 2345
transcription factors (2342) 2342
chemistry, physical (2326) 2326
disease models, animal (2326) 2326
electrodes (2307) 2307
stem cells (2305) 2305
genetically modified animals (2304) 2304
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (33) 33
UofT at Mississauga - Stacks (28) 28
UofT at Scarborough - Stacks (23) 23
Collection Dvlpm't (Acquisitions) - Vendor file (14) 14
Engineering & Comp. Sci. - Stacks (13) 13
Robarts - Stacks (13) 13
Collection Dvlpm't (Acquisitions) - Closed Orders (9) 9
St. Michael's College (John M. Kelly) - 2nd Floor (7) 7
Law (Bora Laskin) - Stacks (6) 6
Earth Sciences (Noranda) - Stacks (5) 5
Trinity College (John W Graham) - Stacks (3) 3
Online Resources - Online (2) 2
University College (Laidlaw) - Stacks (2) 2
UofT at Mississauga - Missing (2) 2
New College (Ivey) - Stacks (1) 1
St. Michael's Hospital - Stacks (1) 1
UTL at Downsview - May be requested (1) 1
UofT at Mississauga - Not Returned (1) 1
Victoria University Emmanuel College - Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (83744) 83744
Chinese (32) 32
French (24) 24
German (19) 19
Japanese (19) 19
Portuguese (8) 8
Spanish (8) 8
Polish (5) 5
Russian (2) 2
Hebrew (1) 1
Korean (1) 1
Turkish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text DEVELOPING AN 'ON AND OFF' SWITCH FOR BREAST CANCER TREATMENT
States News Service, 08/2018
Genetically modified organisms | Breast cancer | Genetic engineering | Research | Drug therapy | T cells
Newspaper Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text FDA APPROVES 'LIVING DRUG' FOR TREATMENT OF AGGRESSIVE BLOOD CANCER
States News Service, 10/2017
Medical colleges | Immunotherapy | Genetically modified organisms | Genetic engineering | Non-Hodgkin's lymphomas | Drug therapy | T cells | Cancer
Newspaper Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Tumor necrosis factor (TNF) receptor superfamily member 1b on CD8+ T cells and TNF receptor superfamily member 1a on non-CD8+ T cells contribute significantly to upper genital tract pathology following chlamydial infection
by Manam, Srikanth and Thomas, Joshua D and Li, Weidang and Maladore, Allison and Schripsema, Justin H and Ramsey, Kyle H and Murthy, Ashlesh K
Journal of Infectious Diseases, ISSN 0022-1899, 06/2015, Volume 211, Issue 12, pp. 2014 - 2022
Background. We demonstrated previously that tumor necrosis factor a (TNF-alpha)- producing Chlamydia-specific CD8(+) T cells cause oviduct pathological... 
Chlamydia | genital infection | CD8 | oviduct pathology | T cells | TNF receptor 2 | TNF receptor 1 | INFECTIOUS DISEASES | ALPHA | MICROBIOLOGY | IMMUNOLOGY | PATHOGENESIS | PROTECTIVE IMMUNITY | MODELS | UROGENITAL INFECTION | DEFICIENT | CD8(+) T cells | CHRONIC DISEASE MANIFESTATIONS | MICE | MURIDARUM INFECTION | CD8-Positive T-Lymphocytes - chemistry | Chlamydia Infections - pathology | Receptors, Tumor Necrosis Factor, Type II - analysis | Animals | Reproductive Tract Infections - pathology | Mice, Inbred C57BL | Female | Receptors, Tumor Necrosis Factor, Type I - analysis | Mice, Knockout | Chlamydia infections | Prevention | Genetically modified mice | Usage | Care and treatment | Tumor necrosis factor | Research | Major and Brief Reports | CD8+ T cells
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Chimeric Antigen Receptor T-Cells (CAR T-Cells) for Cancer Immunotherapy – Moving Target for Industry?
by Salmikangas, Paula and Kinsella, Niamh and Chamberlain, Paul
Pharmaceutical Research, ISSN 0724-8741, 8/2018, Volume 35, Issue 8, pp. 1 - 8
The first CD19 CAR T-cell products, Kymriah and Yescarta, are entering the US market and also being evaluated for marketing authorization in the EU. This... 
Biochemistry, general | Biomedical Engineering | T-cells | Biomedicine | Pharmacy | CAR T | antigen receptor | immunotherapy | Medical Law | genetic modification | Pharmacology/Toxicology | THERAPY | B-CELL | METABOLISM | KINETICS | PHARMACOLOGY & PHARMACY | LEUKEMIA | CHEMISTRY, MULTIDISCIPLINARY | Genetic Engineering - methods | Receptors, Chimeric Antigen - therapeutic use | Immunotherapy, Adoptive - methods | Neoplasms - therapy | Animals | Neoplasms - immunology | Humans | Receptors, Chimeric Antigen - immunology | Receptors, Chimeric Antigen - genetics | T-Lymphocytes - immunology | T-Lymphocytes - transplantation | Antigens | Care and treatment | Immunotherapy | Genetically modified organisms | Drug therapy | T cells | Cancer | CD19 antigen | Hematology | Toxicity | Medical services | T cell receptors | Lymphocytes T | Patients | Industrial development | Manufacturing | Solid tumors | Genetic modification | Expert Review
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Adoptively Transferred Effector Cells Derived from Naïve Rather than Central Memory CD8⁺ T Cells Mediate Superior Antitumor Immunity
by Christian S. Hinrichs and Zachary A. Borman and Lydie Cassard and Luca Gattinoni and Rosanne Spolski and Zhiya Yu and Luis Sanchez-Perez and Pawel Muranski and Steven J. Kern and Carol Logun and Douglas C. Palmer and Yun Ji and Robert N. Reger and Warren J. Leonard and Robert L. Danner and Steven A. Rosenberg and Nicholas P. Restifo and Philippa Marrack
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2009, Volume 106, Issue 41, pp. 17469 - 17474
Effector cells derived from central memory CD8⁺ T cells were reported to engraft and survive better than those derived from effector memory populations,... 
T lymphocytes | Phenotypes | Memory | Stem cells | Cell lines | Immunity | Adoptive transfer | Cells | Tumors | T cell antigen receptors | THERAPY | PROTECTION | IMMUNOTHERAPY | AUTOIMMUNITY | MULTIDISCIPLINARY SCIENCES | TUMOR-REGRESSION | DIFFERENTIATION | CANCER | VIRAL-INFECTION | ANTIGEN | LYMPHOCYTES | Immunotherapy, Adoptive - methods | Animals, Genetically Modified | Humans | Immunophenotyping | Survival Rate | Adoptive Transfer | Animals | Neoplasms - immunology | Autoantigens - immunology | Neoplasms, Experimental - immunology | Primates - immunology | Immunologic Memory | Receptors, Antigen, T-Cell - immunology | Receptors, Antigen, T-Cell - genetics | CD8-Positive T-Lymphocytes - immunology | Biological Sciences
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Adoptive T‐cell therapy for cancer: The era of engineered T cells
by Bonini, Chiara and Mondino, Anna
European Journal of Immunology, ISSN 0014-2980, 09/2015, Volume 45, Issue 9, pp. 2457 - 2469
Tumors originate from a number of genetic events that deregulate homeostatic mechanisms controlling normal cell behavior. The immune system, devoted to patrol... 
Genetic engineering | T‐cell receptor | Chimeric antigen receptor | T cells | Immunotherapy | Adoptive T‐cell therapy | T-cell receptor | Adoptive T-cell therapy | TARGETS TUMOR | IMMUNOLOGY | ANTITUMOR-ACTIVITY | VERSUS-HOST-DISEASE | SUICIDE-GENE | MOUSE MODELS | TUMOR-INFILTRATING LYMPHOCYTES | METASTATIC MELANOMA | HEMATOPOIETIC STEM-CELLS | DONOR LYMPHOCYTES | Antigens, Neoplasm - genetics | Cell- and Tissue-Based Therapy - methods | Gene Expression | Immunotherapy, Adoptive - methods | Genes, Transgenic, Suicide | Antigens, Neoplasm - immunology | Humans | Mutant Chimeric Proteins - genetics | Forecasting | Immunotherapy, Adoptive - trends | T-Lymphocytes - transplantation | Neoplasms - therapy | Cell Engineering - methods | Neoplasms - genetics | T-Lymphocytes - metabolism | Neoplasms - immunology | Mutant Chimeric Proteins - immunology | Receptors, Antigen, T-Cell - immunology | T-Lymphocytes - immunology | Receptors, Antigen, T-Cell - genetics | Neoplasms - pathology | Genetic Therapy - methods | Care and treatment | Health aspects | Genetically modified organisms | Cancer
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Regulatory T cells selectively control CD8+ T cell effector pool size via IL-2 restriction
by Kastenmuller, Wolfgang and Gasteiger, Georg and Subramanian, Naeha and Sparwasser, Tim and Busch, Dirk H and Belkaid, Yasmine and Drexler, Ingo and Germain, Ronald N
Journal of Immunology, ISSN 0022-1767, 09/2011, Volume 187, Issue 6, pp. 3186 - 3197
Regulatory T cells (Treg) are key players in maintaining immune homeostasis but have also been shown to regulate immune responses against infectious pathogens.... 
INTERLEUKIN-2 | RESPONSES | DENDRITIC CELLS | MEMORY | TOLERANCE | MODIFIED VACCINIA VIRUS | IN-VIVO | IMMUNE REGULATION | INFECTION | CTLA-4 | IMMUNOLOGY | T-Lymphocyte Subsets - immunology | Mice, Inbred C57BL | Mice, Transgenic | Reverse Transcriptase Polymerase Chain Reaction | Vaccinia virus - immunology | Mice, Knockout | T-Lymphocytes, Regulatory - immunology | Animals | Interleukin-2 - immunology | Female | Mice | CD8-Positive T-Lymphocytes - immunology | Viral Vaccines - immunology | Immunologic Memory - immunology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Genetically induced tumors in the oncopig model invoke an antitumor immune response dominated by cytotoxic CD8β+ T cells and differentiated γδ T cells alongside a regulatory response mediated by foxp3+ t cells and immunoregulatory molecules
by Overgaard, Nana H and Principe, Daniel R and Schachtschneider, Kyle M and Jakobsen, Jeanne Toft and Rund, Laurie A and Grippo, Paul J and Schook, Lawrence B and Jungersen, Gregers
Frontiers in Immunology, ISSN 1664-3224, 06/2018, Volume 9, p. 1301
In recent years, immunotherapy has shown considerable promise in the management of several malignancies. However, the majority of preclinical studies have been... 
Comparative oncology | Antitumor immunity | T cells | Translational immunology | Porcine cancer model | Immunotherapy | Neoplasms - metabolism | T-Lymphocyte Subsets - immunology | Neoplasms - etiology | Proto-Oncogene Proteins p21(ras) - genetics | Biomarkers, Tumor | Tumor Microenvironment - genetics | Forkhead Transcription Factors - metabolism | Swine | Lymphocytes, Tumor-Infiltrating - metabolism | Disease Models, Animal | T-Lymphocytes, Cytotoxic - immunology | Gene Expression | Genetic Predisposition to Disease | Receptors, Antigen, T-Cell, gamma-delta - metabolism | Animals, Genetically Modified | Immunomodulation | Tumor Microenvironment - immunology | Animals | Lymphocytes, Tumor-Infiltrating - pathology | T-Lymphocytes, Cytotoxic - metabolism | T-Lymphocyte Subsets - metabolism | Biomarkers | Neoplasms - pathology | Cytotoxicity, Immunologic | Lymphocytes, Tumor-Infiltrating - immunology | translational immunology | antitumor immunity | porcine cancer model | immunotherapy | comparative oncology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Soluble c receptor attenuates anti-tumor responses of CD8(+) T cells in T cell immunotherapy
by Kim, G and Hwang, H and Jo, Y and Lee, B and Lee, YH and Kim, CH and Hong, C
INTERNATIONAL JOURNAL OF CANCER, ISSN 0020-7136, 09/2018, Volume 143, Issue 5, pp. 1212 - 1223
Previous studies have shown that soluble common -chain (sc) modulates CD4(+) T cell immunity with antagonistic functions in c cytokine signaling. However, the... 
cytokine | INTERLEUKIN-2 | NATURAL-KILLER | HOMEOSTASIS | ACTIVATION | PHENOTYPE | IL-15 | IL-2 | NAIVE | adoptive T cell transfer | soluble common gamma chain receptor | ONCOLOGY | cancer immunotherapy | IN-VIVO | COMMON GAMMA-CHAIN | EXPRESSION | Antigens | Oncology, Experimental | Immunotherapy | Genetically modified organisms | Research | T cells | Cancer | Tumors
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Human CD8<>+<> T-Cell Responses Against the 4 Dengue Virus Serotypes Are Associated with Distinct Patterns of Protein Targets
by Weiskopf, Daniela and Cerpas, Cristhiam and Angelo, Michael A and Bangs, Derek J and Sidney, John and Paul, Sinu and Peters, Bjoern and Sanches, Françoise P and Silvera, Cassia G. T and Costa, Priscilla R and Kallas, Esper G and Gresh, Lionel and De Silva, Aruna D and Balmaseda, Angel and Harris, Eva and Sette, Alessandro
Journal of Infectious Diseases, ISSN 0022-1899, 2015, Volume 212, Issue 10, pp. 1743 - 1751
Background. All 4 dengue virus (DENV) serotypes are now simultaneously circulating worldwide and responsible for up to 400 million human infections each year.... 
Serotype specific | Nicaragua | Sri Lanka | CD8 | Brazil | Dengue virus | T cells | sup | INFECTIOUS DISEASES | EFFICACY | dengue virus | VACCINE | CLASS-I SUPERTYPES | MICROBIOLOGY | IMMUNOLOGY | serotype specific | INHIBITION | SECONDARY INFECTION | PROTECTIVE ROLE | CD8(+) T cells | EPIDEMIC | Dengue Virus - classification | Dengue Virus - immunology | Humans | Dengue - epidemiology | Serogroup | Viral Proteins - immunology | CD8-Positive T-Lymphocytes - immunology | Dengue - immunology | Genetically modified mice | Research | Children | Health aspects | Dengue viruses | Major and Brief Reports | CD8+ T cells
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Designer T-cells and T-cell receptors for customized cancer immunotherapies
by Legut, Mateusz and Sewell, Andrew K
Current Opinion in Pharmacology, ISSN 1471-4892, 08/2018, Volume 41, pp. 96 - 103
T-cell receptors (TCRs) can be used to re-direct patients’ immune system to cancer. Directed evolution can enhance TCR affinity towards cancer antigens.... 
REGRESSION | BINDING-AFFINITY | REACTIVITY | PHARMACOLOGY & PHARMACY | PERIPHERAL-BLOOD | GENE-THERAPY | GENERATION | TOXICITY | IDENTIFICATION | ANTIGEN RECEPTOR | LYMPHOCYTES | Immunotherapy - methods | Neoplasms - therapy | Antigens, Neoplasm - immunology | Neoplasms - immunology | Humans | Protein Engineering | Receptors, Antigen, T-Cell - immunology | T-Lymphocytes - immunology | Receptors, Antigen, T-Cell - genetics | Medical colleges | Care and treatment | Immunotherapy | Genomics | Genetically modified organisms | Genetic engineering | Drug therapy | T cells | Cancer
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text Human asymptomatic epitope peptide/ CXCL10-based prime/pull vaccine induces herpes simplex virus-specific gamma interferon-positive CD107+ CD8+ T cells that infiltrate the corneas and trigeminal ganglia of humanized HLA transgenic rabbits and protect against ocular herpes challenge
by Khan, Arif A and Srivastava, Ruchi and Vahed, Hawa and Roy, Soumyabrata and Walia, Sager S and Kim, Grace J and Fouladi, Mona A and Yamada, Taikun and Ly, Vincent T and Lam, Cynthia and Lou, Anthony and Nguyen, Vivianna and Boldbaatar, Undariya and Geertsema, Roger and Fraser, Nigel W and BenMohamed, Lbachir
Journal of Virology, ISSN 0022-538X, 08/2018, Volume 92, Issue 16
Herpes simplex virus 1 (HSV-1) is a prevalent human pathogen that infects the cornea, causing potentially blinding herpetic disease. A clinical herpes vaccine... 
CXCL10 | HSV-1 | HLA transgenic rabbit | Ocular | Prime/pull vaccine | CD8 | T cell | Prime/pull | Herpes | Herpes simplex | GLYCOPROTEIN B | EYE DISEASE | CD8(+) T cell | prime/pull vaccine | PERIOCULAR VACCINATION | ocular | herpes simplex | EFFECTOR | STROMAL KERATITIS | VIROLOGY | herpes | prime/pull | GENITAL HERPES | SYSTEMIC VACCINATION | ANIMAL-MODELS | INFECTION | TYPE-1 LATENCY | T-Lymphocyte Subsets - immunology | Humans | Cornea - immunology | HLA Antigens - genetics | Herpes Simplex Virus Vaccines - immunology | Viral Load | Epitopes - immunology | Keratitis, Herpetic - pathology | Herpes Simplex Virus Vaccines - administration & dosage | Disease Models, Animal | Rabbits | Keratitis, Herpetic - virology | Animals, Genetically Modified | Keratitis, Herpetic - prevention & control | Vaccines, Subunit - immunology | HLA Antigens - metabolism | Trigeminal Ganglion - immunology | Lysosomal-Associated Membrane Protein 1 - analysis | Chemokine CXCL10 - administration & dosage | Interferon-gamma - analysis | Animals | Vaccines, Subunit - administration & dosage | Simplexvirus - isolation & purification | Simplexvirus - immunology | CD8-Positive T-Lymphocytes - immunology | Chemokine CXCL10 - metabolism
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text Modified vaccinia Ankara‐expressing Ag85A, a novel tuberculosis vaccine, is safe in adolescents and children, and induces polyfunctional CD4+ T cells
by Scriba, Thomas J and Tameris, Michele and Mansoor, Nazma and Smit, Erica and van der Merwe, Linda and Isaacs, Fatima and Keyser, Alana and Moyo, Sizulu and Brittain, Nathaniel and Lawrie, Alison and Gelderbloem, Sebastian and Veldsman, Ashley and Hatherill, Mark and Hawkridge, Anthony and Hill, Adrian V. S and Hussey, Gregory D and Mahomed, Hassan and McShane, Helen and Hanekom, Willem A
European Journal of Immunology, ISSN 0014-2980, 01/2010, Volume 40, Issue 1, pp. 279 - 290
Modified vaccinia Ankara‐expressing Ag85A (MVA85A) is a new tuberculosis (TB) vaccine aimed at enhancing immunity induced by BCG. We investigated the safety... 
Vaccine | Tuberculosis | IL‐17 | Polyfunctional | Modified vaccinia Ankara‐expressing Ag85A | Modified vaccinia ankara-expressing Ag85A | IL-17 | MYCOBACTERIUM-TUBERCULOSIS | IMMUNE-RESPONSE | Modified vaccinia Ankara-expressing Ag85A | BCG | CYTOKINE | IMMUNOLOGY | VIRUS ANKARA | TUMOR-NECROSIS-FACTOR | IMMUNOGENICITY | RECOMBINANT | INFECTION | ANTIGEN 85A | Tuberculosis Vaccines - adverse effects | Humans | Antigens, Bacterial - immunology | Child, Preschool | Acyltransferases - immunology | Infant | Male | Acyltransferases - genetics | Antigens, Bacterial - genetics | Vaccinia virus - genetics | CD4-Positive T-Lymphocytes - immunology | Tuberculosis - immunology | Tuberculosis - prevention & control | Adolescent | Female | Immunologic Memory | Tuberculosis Vaccines - immunology | Child
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
14. Full Text Plant-based oral tolerance to hemophilia therapy employs a complex immune regulatory response including LAP + CD4 + T cells
by Wang, Xiaomei and Su, Jin and Sherman, Alexandra and Rogers, Geoffrey L and Liao, Gongxian and Hoffman, Brad E and Leong, Kam W and Terhorst, Cox and Daniell, Henry and Herzog, Roland W
Blood, ISSN 0006-4971, 04/2015, Volume 125, Issue 15, pp. 2418 - 2427
Coagulation factor replacement therapy for the X-linked bleeding disorder hemophilia is severely complicated by antibody ("inhibitor") formation. We previously... 
INHIBITOR FORMATION | B-CELL | DENDRITIC CELLS | LETTUCE CHLOROPLASTS | FACTOR-IX | FACTOR-VIII | LONG-TERM TOLERANCE | ANTIGEN-SPECIFIC EFFECTOR | GENE-TRANSFER | HEMATOLOGY | IMMUNOLOGICAL-TOLERANCE | Hemophilia B - therapy | Recombinant Fusion Proteins - immunology | Transforming Growth Factor beta - immunology | Factor IX - administration & dosage | Hemophilia B - immunology | Factor IX - immunology | Plants, Genetically Modified - genetics | Administration, Oral | Factor IX - therapeutic use | Humans | Recombinant Fusion Proteins - therapeutic use | Factor IX - genetics