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Vaccine, ISSN 0264-410X, 10/2017, Volume 35, Issue 42, pp. 5714 - 5721
Hepatitis B core Antigen (HBcAg) assembled into Capsid-Like Particles (CLPs) is investigated as a therapeutic vaccine in treatment of chronic hepatitis B (CHB)... 
HBcAg | Immune response | Plant-derived biopharmaceuticals | Chronic hepatitis B | Therapeutic vaccine | IgG isotypes | SYSTEM | MEDICINE, RESEARCH & EXPERIMENTAL | VACCINE | IMMUNOLOGY | CORE ANTIGEN | HIGH-LEVEL PRODUCTION | CAPSID PROTEINS | GENOTYPES | SURFACE | VIRUS-LIKE PARTICLES | HEPATITIS-B | EXPRESSION | Plants, Genetically Modified - genetics | Immunization - methods | Vaccines - immunology | Th2 Cells - immunology | Th1 Cells - immunology | Hepatitis B Core Antigens - genetics | Hepatitis B Core Antigens - immunology | Epitopes - immunology | Vaccines - genetics | Animals | Escherichia coli - genetics | Immunoglobulin G - immunology | Tobacco - genetics | Hepatitis B virus - genetics | Female | Mice | Mice, Inbred BALB C | Hepatitis B Antibodies - immunology | Hepatitis B virus - immunology | Biotechnology | Genetic engineering | Genetically engineered foods | Food | Medical research | Biological products | Immunoglobulin G | Escherichia coli | Plant genetics | Hepatitis | Analysis | Medicine, Experimental | Antigenic determinants | Yeast | Sucrose | Centrifugation | Viruses | Lymphocytes T | Vaccines | Transgenic plants | Proteins | Isotypes | Antigenicity | Life sciences | Hepatitis B virus | Sugars | Enzyme-linked immunosorbent assay | Polyclonal antibodies | Immune system | Antigens | Purification | Hepatitis B core antigen | Epitopes | Plants | Tobacco | Core protein | Diagnostic systems
Journal Article
Vaccine, ISSN 0264-410X, 2011, Volume 29, Issue 38, pp. 6532 - 6539
Journal Article
Developmental and Comparative Immunology, ISSN 0145-305X, 05/2012, Volume 37, Issue 1, pp. 107 - 114
► We have successfully expressed a viral protein on the surface of Saccharomyces yeast. ► This delivery system stimulates naïve T cells even when using... 
BVD | Dectin-1 | Cattle | Saccharomyces cerevisiae | TLR2 | IMMUNE-RESPONSE | DENDRITIC CELLS | MACROPHAGES | VIRAL DIARRHEA VIRUS | IMMUNOLOGY | LIVE | TOLL-LIKE RECEPTOR-2 | REACTIVE OXYGEN | ZOOLOGY | INFECTION | VACCINES | Th1 Cells - physiology | Cell Proliferation | Reactive Oxygen Species - metabolism | Th2 Cells - physiology | Saccharomyces cerevisiae - genetics | Viral Vaccines - genetics | Viral Vaccines - metabolism | Male | Th2 Cells - immunology | Interferon-gamma - metabolism | Th1 Cells - immunology | Th2 Cells - microbiology | Saccharomyces cerevisiae - metabolism | Viral Envelope Proteins - metabolism | Membrane Proteins - metabolism | Interleukin-8 - metabolism | Organisms, Genetically Modified | Recombinant Proteins - metabolism | Vaccines, Subunit | Viral Envelope Proteins - genetics | Saccharomyces cerevisiae - immunology | Membrane Proteins - genetics | Interleukin-4 - metabolism | Cells, Cultured | Membrane Proteins - immunology | Recombinant Proteins - genetics | Diarrhea Viruses, Bovine Viral - immunology | Macrophages - metabolism | Th1 Cells - microbiology | Animals | Recombinant Proteins - immunology | Viral Envelope Proteins - immunology | Viral Vaccines - immunology | Viral proteins | T cells | Cell culture | Reactive oxygen species | Immune response | Helper cells | Diarrhea | Envelope protein | Heat inactivation | Lymphocytes T | Pattern recognition | Vaccines | Macrophages | Immunity (cell-mediated) | CD4 antigen | Interleukin 4 | E2 protein | Immunogenicity | Antigen-presenting cells | TLR2 protein | Interleukin 10 | Toll-like receptors | gamma -Interferon | Chemokines
Journal Article
Journal Article
Journal of Clinical Immunology, ISSN 0271-9142, 8/2011, Volume 31, Issue 4, pp. 666 - 680
We examined the role of macrophage migration inhibitory factor (MIF) in the generation of the Th2 response using MIF-deficient mice in a model of epicutaneous... 
Medical Microbiology | Biomedicine | Immunology | macrophage migration inhibitory factor | Atopic inflammation | Infectious Diseases | Internal Medicine | Th2 response | Macrophage migration inhibitory factor | FACTOR MIF | INTERLEUKIN-4 RECEPTOR | ALLERGIC AIRWAY INFLAMMATION | IMMUNOLOGY | CYTOKINE GENE-EXPRESSION | DELAYED-TYPE HYPERSENSITIVITY | ATOPIC-DERMATITIS | EOSINOPHIL RECRUITMENT | REGULATORY ROLE | NF-KAPPA-B | T-CELLS | Intramolecular Oxidoreductases - immunology | Cell Proliferation | Ovalbumin - immunology | Macrophage Migration-Inhibitory Factors - immunology | Pneumonia - pathology | Hypersensitivity, Immediate | Th2 Cells - immunology | Administration, Cutaneous | Macrophages | Interleukin-2 - immunology | Macrophage Migration-Inhibitory Factors - deficiency | Macrophage Migration-Inhibitory Factors - genetics | Antigens, Differentiation, B-Lymphocyte - immunology | Pneumonia - immunology | Female | Histocompatibility Antigens Class II - metabolism | Cytokines - immunology | Antigens, Differentiation, B-Lymphocyte - genetics | Immunization | Lung - pathology | Intramolecular Oxidoreductases - deficiency | Lymph Nodes - immunology | Administration, Intranasal | Antigen-Presenting Cells - immunology | Mice, Knockout | Animals | Bone Marrow Cells | Histocompatibility Antigens Class II - immunology | Ovalbumin - administration & dosage | Intramolecular Oxidoreductases - genetics | Antibodies, Monoclonal - administration & dosage | CD3 Complex - immunology | Mice | Mice, Inbred BALB C | Antigens, Differentiation, B-Lymphocyte - metabolism | Histocompatibility Antigens Class II - genetics | Interleukin-2 - biosynthesis | Cytokines - biosynthesis | Lung - immunology | Genetically modified animals | Medical colleges | Antigens | Analysis | Albumin | Animal genetic engineering | Inflammation | T cells | atopic inflammation
Journal Article
International Archives of Allergy and Immunology, ISSN 1018-2438, 03/2001, Volume 124, Issue 1-3, pp. 126 - 129
Exposure to foreign antigens is an essential element of all immune responses, including allergic sensitization. For some allergens (e.g. mite and cockroach),... 
Environmental and Genetic Risk Factors | Tolerance | Mite | Cat allergen | Modified Th2 | Asthma
Journal Article
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, ISSN 0091-6749, 02/2016, Volume 137, Issue 2, pp. 388 - 389
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2013, Volume 123, Issue 4, pp. 1457 - 1474
Journal Article
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, ISSN 0091-6749, 12/2015, Volume 136, Issue 6, pp. 1627 - U302
Background: In human subjects, allergen tolerance has been observed after high-dose allergen exposure or after completed allergen immunotherapy, which is... 
CD154 | IGE | T(H)2 cells | Cat allergy | IgG4 | Fel d 4 | asthma | class II tetramer | INDUCTION | IMMUNOLOGY | Fel d 1 | allergen tolerance | IMMUNOGLOBULIN G4 | allergen exposure | B-CELLS | ALLERGY | POLLEN IMMUNOTHERAPY | SWITCH | DIFFERENTIATION | MODIFIED TH2 RESPONSE | IMMUNE TOLERANCE
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2009, Volume 124, Issue 2, pp. 292 - 300.e97
Journal Article
NATURE REVIEWS IMMUNOLOGY, ISSN 1474-1733, 03/2007, Volume 7, Issue 3, pp. 220 - 230
There is no immunological mechanism to adequately explain the sudden epidemic in allergies noted in the last 30 years in developed countries. The reduction in... 
SCHOOL-AGE-CHILDREN | ALTERNATIVELY ACTIVATED MACROPHAGES | HYGIENE HYPOTHESIS | CAT ALLERGEN | SELECTIVE UP-REGULATION | SCHISTOSOMA-MANSONI INFECTION | REGULATORY T-CELLS | TRICHURIS-SUIS THERAPY | IMMUNOLOGY | MODIFIED TH2 RESPONSE | MURINE SCHISTOSOMIASIS
Journal Article
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, ISSN 1018-2438, 01/2001, Volume 124, Issue 1-3, pp. 126 - 129
Exposure to foreign antigens is an essential element of all immune responses, including allergic sensitization. For some allergens (e.g. mite and cockroach),... 
ENVIRONMENT | RISK | asthma | ALLERGEN | IMMUNOLOGY | SMOOTH-MUSCLE | ALLERGY | SENSITIZATION | modified Th2 | ASSOCIATION | cat allergen | mite | tolerance | INNER-CITY CHILDREN
Journal Article