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Journal Article
Molecular Cell, ISSN 1097-2765, 08/2017, Volume 67, Issue 3, pp. 387 - 399.e5
The DNA-mediated innate immune response underpins anti-microbial defenses and certain autoimmune diseases. Here we used immunoprecipitation, mass spectrometry,... 
HEXIM1 | DNA-PK | innate immune response | herpesvirus | paraspeckles | cGAS | NEAT1 | interferon stimulatory DNA | DEFENSE | PROTEIN | INHIBITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | SENSOR | POLYMERASE-II | 7SK RNA | BINDING | GMP-AMP SYNTHASE | P-TEFB | CELL BIOLOGY | Human Umbilical Vein Endothelial Cells - metabolism | Humans | Octamer Transcription Factors - immunology | Intracellular Signaling Peptides and Proteins - metabolism | Herpesvirus 8, Human - immunology | RNA, Long Noncoding - immunology | PTB-Associated Splicing Factor - genetics | RNA Interference | Calcium-Binding Proteins - immunology | Octamer Transcription Factors - genetics | Nucleotidyltransferases - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Signal Transduction | Membrane Proteins - genetics | RNA-Binding Proteins - immunology | PTB-Associated Splicing Factor - metabolism | Nuclear Matrix-Associated Proteins - metabolism | PTB-Associated Splicing Factor - immunology | DNA - metabolism | Host-Pathogen Interactions | Nuclear Matrix-Associated Proteins - genetics | HeLa Cells | RNA-Binding Proteins - metabolism | Calcium-Binding Proteins - genetics | RNA-Binding Proteins - genetics | Multiprotein Complexes | Human Umbilical Vein Endothelial Cells - immunology | Intracellular Signaling Peptides and Proteins - immunology | Human Umbilical Vein Endothelial Cells - virology | Interferon Regulatory Factor-3 - genetics | Ku Autoantigen - genetics | Transfection | HEK293 Cells | Membrane Proteins - metabolism | Nuclear Proteins - genetics | Octamer Transcription Factors - metabolism | Interferon Regulatory Factor-3 - immunology | Calcium-Binding Proteins - metabolism | DNA - immunology | Nuclear Matrix-Associated Proteins - immunology | Ku Autoantigen - immunology | Membrane Proteins - immunology | Nuclear Proteins - metabolism | Ku Autoantigen - metabolism | RNA, Long Noncoding - genetics | Immunity, Innate | Nuclear Proteins - immunology | DNA - genetics | Interferon Regulatory Factor-3 - metabolism | Nucleotidyltransferases - genetics | Protein Binding | Nucleotidyltransferases - immunology | RNA, Long Noncoding - metabolism | RNA sequencing | Immune response | RNA | DNA | Genetic research | Interferon | Biological response modifiers | Mass spectrometry | Human Umbilical Vein Endothelial Cells | Nuclear Matrix-Associated Proteins | Herpesvirus 8, Human | RNA-Binding Proteins | Life Sciences | Interferon Regulatory Factor-3 | Genetics | Calcium-Binding Proteins | Intracellular Signaling Peptides and Proteins | PTB-Associated Splicing Factor | Nuclear Proteins | Membrane Proteins | Nucleotidyltransferases | Ku Autoantigen | Octamer Transcription Factors | RNA, Long Noncoding
Journal Article
Vaccine, ISSN 0264-410X, 2013, Volume 32, Issue 2, pp. 223 - 229
Journal Article
Journal Article
Frontiers in Physiology, ISSN 1664-042X, 04/2016, Volume 7, p. 142
Glutathione (GSH) deficits have been observed in several mental or degenerative illness, and so has the metabolic syndrome. The impact of a decreased glucose... 
Resident-intruder stress | GCLM knockout | Glycogen | Cortisol | Insulin | Glycemia | Glutathione | OXIDATIVE STRESS | PHYSIOLOGY | insulin | glutathione | MODIFIER SUBUNIT | SCHIZOPHRENIA | glycogen | BIPOLAR DISORDER | cortisol | GLUCOSE-HOMEOSTASIS | REACTIVE OXYGEN | resident-intruder stress | DISEASE | glycemia | NEURONS | MICE | Cysteine | Ligases | Health aspects | Liver | Resident-intruder paradigm
Journal Article
The EMBO Journal, ISSN 0261-4189, 08/2010, Volume 29, Issue 15, pp. 2611 - 2622
Journal Article
Immunology, ISSN 0019-2805, 09/2009, Volume 128, Issue 1pt2, pp. e816 - e825
Summary Interleukin‐27 (IL‐27) is a new IL‐12‐related heterodimeric cytokine comprising a novel p28 molecule and the Epstein–Barr‐virus‐induced gene 3 (EBI3)... 
cytokines | cytokine receptors | T cells | tolerance | anergy | Cytokine receptors | Tolerance | Anergy | Cytokines | IL-12 P40 HOMODIMER | CARCINOMA-CELLS | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | TH1 RESPONSES | DENDRITIC CELLS | CD4(+) T-CELLS | CYTOKINE | INDUCED GENE-3 | IMMUNOLOGY | INDUCED ARTHRITIS | EXPRESSION | Receptors, Interleukin-12 - immunology | Cell Adhesion Molecules - agonists | Graft Survival - immunology | Phosphorylation | Protein Subunits - pharmacology | Protein Subunits - immunology | Minor Histocompatibility Antigens | Interferon-gamma - drug effects | Interleukin-17 - immunology | Cercopithecus aethiops | Cell Adhesion Molecules - immunology | Interleukin-17 - pharmacology | Th1 Cells - immunology | CD4-Positive T-Lymphocytes - immunology | Th1 Cells - metabolism | Myoblasts - metabolism | STAT1 Transcription Factor - metabolism | STAT1 Transcription Factor - agonists | Female | Receptors, Cytokine - genetics | Protein Subunits - genetics | T-Lymphocytes, Cytotoxic - immunology | Transduction, Genetic | Mice, Inbred C57BL | Interleukin-17 - genetics | Receptors, Interleukin-12 - agonists | Cell Adhesion Molecules - metabolism | STAT1 Transcription Factor - immunology | Myoblasts - immunology | Animals | Receptors, Interleukin-12 - metabolism | T-Lymphocytes, Cytotoxic - metabolism | Neoplasms - immunology | Interferon-gamma - immunology | Cell Line, Tumor | Receptors, Cytokine - immunology | Mice | Mice, Inbred BALB C | COS Cells | CD4-Positive T-Lymphocytes - drug effects | Interferon-gamma - biosynthesis | Immune response | Interleukins | Oncology, Experimental | Research | Biological response modifiers | Health aspects | Interferon gamma | Cancer | Original
Journal Article
JOURNAL OF PHYSIOLOGY-LONDON, ISSN 0022-3751, 08/2019, Volume 597, Issue 16, pp. 4293 - 4307
Key points Dravet syndrome mice (Scn1a(+/-)) demonstrate a marked strain dependence for the severity of seizures which is correlated with GABA(A) receptor... 
LOCALIZATION | SODIUM | PHYSIOLOGY | GENETIC MODIFIER | SUBTYPES | GABA receptor | CURRENTS | NEUROSCIENCES | Dravet syndrome | BENZODIAZEPINE | EPILEPSY | alpha subunit | ANTIEPILEPTIC DRUG | HIPPOCAMPAL PYRAMIDAL CELLS | MODULATION
Journal Article