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Cell (Cambridge), ISSN 0092-8674, 2010, Volume 141, Issue 6, pp. 1068 - 1079
Elucidation of molecular mechanisms that regulate synapse formation is required for the understanding of neural wiring, higher brain functions, and mental... 
PROTEINS | MOLNEURO | Proteins | Molneuro
Journal Article
Neuron (Cambridge, Mass.), ISSN 0896-6273, 2007, Volume 53, Issue 5, pp. 703 - 717
Glycogen synthase kinase-3 (GSK3) has been implicated in major neurological disorders, but its role in normal neuronal function is largely unknown. Here we... 
CELLBIO | MOLNEURO
Journal Article
Molecular cell, ISSN 1097-2765, 2006, Volume 22, Issue 6, pp. 795 - 806
The inositol 1,4,5-trisphosphate (IP 3) receptors (IP 3Rs) are IP 3-gated intracellular Ca 2+ channels. We previously identified an IP 3R binding protein,... 
MOLNEURO | SIGNALING
Journal Article
Neuron (Cambridge, Mass.), ISSN 0896-6273, 06/2007, Volume 54, Issue 5, pp. 713 - 720
The apolipoprotein E (APOE) ε4 allele is the best established genetic risk factor for late-onset Alzheimer's disease (LOAD). We conducted genome-wide surveys... 
HUMDISEASE | MOLNEURO
Journal Article
Cell (Cambridge), ISSN 0092-8674, 2009, Volume 139, Issue 2, pp. 380 - 392
Synapses are asymmetric cellular adhesions that are critical for nervous system development and function, but the mechanisms that induce their formation are... 
MOLNEURO
Journal Article
Neuron (Cambridge, Mass.), ISSN 0896-6273, 2008, Volume 58, Issue 5, pp. 749 - 762
At synapses, cell adhesion molecules (CAMs) provide the molecular framework for coordinating signaling events across the synaptic cleft. Among synaptic CAMs,... 
CELLBIO | MOLNEURO
Journal Article
Cell (Cambridge), ISSN 0092-8674, 2007, Volume 129, Issue 2, pp. 397 - 410
Spatial working memory (WM; i.e., “scratchpad” memory) is constantly updated to guide behavior based on representational knowledge of spatial position. It is... 
MOLNEURO
Journal Article
Neuron (Cambridge, Mass.), ISSN 0896-6273, 06/2007, Volume 54, Issue 5, pp. 755 - 770
Ca2+ signaling plays a central role in activity-dependent regulation of dendritic arborization, but key molecular mechanisms downstream of calcium elevation... 
CELLBIO | DEVBIO | MOLNEURO
Journal Article
Neuron (Cambridge, Mass.), ISSN 0896-6273, 2008, Volume 60, Issue 1, pp. 123 - 136
α6-containing (α6 ∗) nicotinic ACh receptors (nAChRs) are selectively expressed in dopamine (DA) neurons and participate in cholinergic transmission. We... 
SYSNEURO | MOLNEURO
Journal Article
Developmental cell, ISSN 1534-5807, 2007, Volume 12, Issue 4, pp. 587 - 602
Neural activity regulates dendrite and synapse development, but the underlying molecular mechanisms are unclear. Ca 2+/calmodulin-dependent protein kinase II... 
PROTEINS | MOLNEURO
Journal Article
Neuron (Cambridge, Mass.), ISSN 0896-6273, 2007, Volume 53, Issue 3, pp. 439 - 452
Hallucinogens, including mescaline, psilocybin, and lysergic acid diethylamide (LSD), profoundly affect perception, cognition, and mood. All known drugs of... 
HUMDISEASE | MOLNEURO | SIGNALING
Journal Article
Neuron (Cambridge, Mass.), ISSN 0896-6273, 2008, Volume 59, Issue 2, pp. 214 - 225
Alzheimer's disease is characterized by the deposition of senile plaques and progressive dementia. The molecular mechanisms that couple plaque deposition to... 
HUMDISEASE | MOLNEURO | SIGNALING | AMYLOID DEPOSITION | CORTICAL-NEURONS | CA2 | ALZHEIMERS-DISEASE | MOUSE MODEL | MUTANT PRESENILIN-1 | HIPPOCAMPAL-NEURONS | CHANNEL ACTIVITY | NEUROSCIENCES | TRANSGENIC MICE | SYNAPTIC DEPRESSION
Journal Article
Current biology, ISSN 0960-9822, 2009, Volume 19, Issue 5, pp. 386 - 390
Sleep is regulated by a circadian clock that times sleep and wake to specific times of day and a homeostat that drives sleep as a function of prior wakefulness... 
MOLNEURO
Journal Article
Neuron (Cambridge, Mass.), ISSN 0896-6273, 2008, Volume 58, Issue 5, pp. 681 - 693
Apolipoprotein E is associated with age-related risk for Alzheimer's disease and plays critical roles in Aβ homeostasis. We report that ApoE plays a role in... 
CELLBIO | HUMDISEASE | MOLNEURO | INSULIN-DEGRADING ENZYME | ALZHEIMERS-DISEASE | HUMAN APOLIPOPROTEIN-E | IN-VIVO | CHOLESTEROL EFFLUX | DENSITY-LIPOPROTEIN | CENTRAL-NERVOUS-SYSTEM | AMYLOID PRECURSOR PROTEIN | TRANSGENIC MOUSE MODEL | NEUROSCIENCES | LIVER-X-RECEPTOR
Journal Article
Neuron (Cambridge, Mass.), ISSN 0896-6273, 2007, Volume 55, Issue 6, pp. 859 - 873
NF-κB signaling has been implicated in neurodegenerative disease, epilepsy, and neuronal plasticity. However, the cellular and molecular activity of NF-κB... 
DEVBIO | MOLNEURO | SIGNALING
Journal Article